{"title":"Dialysability of theophylline.","authors":"N D Vaziri, C H Barton, R Ness, D Clark","doi":"10.3109/08860227809080090","DOIUrl":"https://doi.org/10.3109/08860227809080090","url":null,"abstract":"<p><p>We have shown that theophylline is highly dialysable with an average dialysis clearance of 76 ml/min approaching 63% of urea clearance with hemodialysis. Implications include dose adjustment during dialysis and efficacy of dialytic technique in the treatment of theophylline intoxication.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 3","pages":"243-9"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809080090","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11922377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An outbreak of dialysis dementia due to aluminum in the dialysate.","authors":"V V Rozas, F K Port, R E Easterling","doi":"10.3109/08860227809080099","DOIUrl":"https://doi.org/10.3109/08860227809080099","url":null,"abstract":"<p><p>The dialysis dementia syndrome was observed in eight of 21 patients dialyzed in a small center during a 22-month period in which dialysate contained aluminum levels of 618 microgram/liter. This incidence of 38% was significantly higher than the zero incidence of four prior years when no aluminum was added to city water (p less than 0.05) and also when compared to the zero incidence in the 2.5 years subsequent to deionization of dialysis water which lowered its aluminum content to less than 1 microgram/liter (p less than 0.0002). Since other factors were not altered, we conclude that aluminum intoxication from the dialysate was the cause for the outbreak of this progressive encephalopathy.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 5-6","pages":"459-70"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809080099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11950372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Zelman, P Whittam, P Sullo, R Parsons, E Anzola, D Gisser
{"title":"Hyper/hypo-osmotic peritoneal dialysis.","authors":"A Zelman, P Whittam, P Sullo, R Parsons, E Anzola, D Gisser","doi":"10.3109/08860227809080101","DOIUrl":"https://doi.org/10.3109/08860227809080101","url":null,"abstract":"<p><p>This report concerns the augmentation of peritoneal dialysis using alternating hyper/hypoosmotic peritoneal dialysates, and covers a detailed examination of the longest lived, anephric goat to be maintained using this delivery system. Experimental results show that with this technique: 1) urea clearance can be increased some 200% over control values, 2) the convective transport of urea is unimportant and the increased urea clearance is due primarily to increased peritoneal permeability, 3) net ultrafiltration and electrolyte balance can be easily controlled by variation of total electrolyte and glucose about an appropriate mean. A detailed autopsy failed to demonstrate any gross or microscopic pathology.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 5-6","pages":"483-93"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809080101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11950373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Locus of control and degree of compliance in hemodialysis patients.","authors":"W J Wenerowicz, J H Riskind, P G Jenkins","doi":"10.3109/08860227809080102","DOIUrl":"https://doi.org/10.3109/08860227809080102","url":null,"abstract":"<p><p>An experiment was conducted to test the hypothesis that dialysis patients with an internal locus of control orientation will show a higher rate of compliance to medication and dietary restrictions than those patients with an external locus of control. The results strongly supported the hypothesis. The possibility of interventions to modify patient locus of control is discussed, as is the use of this widely studied personality variable in predicting patient compliance.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 5-6","pages":"495-505"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809080102","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11950374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G H Mayor, J A Keiser, T V Sanchez, S M Sprague, J B Hook
{"title":"Factors affecting tissue aluminum concentration.","authors":"G H Mayor, J A Keiser, T V Sanchez, S M Sprague, J B Hook","doi":"10.3109/08860227809080100","DOIUrl":"https://doi.org/10.3109/08860227809080100","url":null,"abstract":"<p><p>Elevated concentration of aluminum has been reported in serum, whole blood and tissue samples of patients with renal insufficiency. Evidence incriminating aluminum as a neurotoxin among the dialysis population is strong. The source of this aluminum has not been clearly defined, although both gastrointestinal and parenteral routes may be involved. Data from this laboratory suggest that an effect of parathyroid hormone on tissue aluminum burdens may, in part, explain why only certain patients exposed to high dialysate aluminum develop the dialysis encephalopathy syndrome and the occasional occurrence of this syndrome in the absence of dialysis or increased dialysate aluminum.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 5-6","pages":"471-81"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809080100","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11583496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrafiltration followed by haemodialysis. A longterm trial and acute studies.","authors":"A M Pierides, S B Kurtz, W J Johnson","doi":"10.3109/08860227809079320","DOIUrl":"https://doi.org/10.3109/08860227809079320","url":null,"abstract":"<p><p>Separate ultrafiltration followed by haemodialysis (U.F.-H.D.) using Gambro Major or Cordis-Dow hollow-fiber dialyzers were evaluated in 10 dialysis patients over a mean period of 4 1/2 months and 455 U.F.-H.D. procedures. Fluid control was facilitated in oedematous patients but the number of hypotensive episodes during the combined procedure requiring intravenous 5% saline did not significantly decrease. No significant improvement in hypertension was noted. Ultrafiltration (U.F.) alone for acutely water overloaded, azotaemic patients proved very useful. Two to five liters of oedema fluid could be removed asymptomatically in one to three hours using transmembrane pressures of 250 to 500 mmHg and U.F. rates of 10 to 42 ml/min. Two patients became acutely and symptomatically hypotensive. One was an insulin dependent diabetic in whom 3800 ml were removed in 75 minutes and the other a hypertensive patient undergoing treatment with Minoxidil and propranolol.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 4","pages":"325-45"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809079320","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11922290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y Aizawa, A Shibata, T Ohmori, A Kamimura, S Takahashi, Y Hirasawa
{"title":"Hemodynamic effects of acetate in man.","authors":"Y Aizawa, A Shibata, T Ohmori, A Kamimura, S Takahashi, Y Hirasawa","doi":"10.3109/08860227809080089","DOIUrl":"https://doi.org/10.3109/08860227809080089","url":null,"abstract":"<p><p>To determine the action of acetate in man, 1.7mEq/ml of sodium acetate was infused in 10 patients on chronic hemodialysis. It was administered intravenously in 1.5mEq/min for 5 min followed by 3.8mEq/min for another 5 min. As control, 1.71mEq/ml of sodium chloride was infused in a similar manner. Following the infusion of sodium acetate, heart rate increased slightly but significantly (p less than 0.01). Limb blood flow measured in an upper limb by the venous occlusion method, showed an increase in all of them and it was significant( p less than 0.001). The peripheral vascular resistance (=mean arterial blood pressure/limb blood flow) showed a significant fall (p less than 0.001). The analysis of systolic time interval showed a change suggestive of depression of heart function at the end of sodium acetate infusion (p less than 0.05). Such a vasodilating effect or a change in heart function was not observed following sodium chloride infusion. A depressant action of acetate upon the cardiovascular system may be, therefore, concluded.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 3","pages":"235-42"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809080089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11922375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful coronary artery bypass in hemodialysis patients.","authors":"L H Byrd","doi":"10.3109/08860227809103862","DOIUrl":"https://doi.org/10.3109/08860227809103862","url":null,"abstract":"<p><p>Cardiovascular disease is the major casue of death in maintenance hemodialysis patients. We report two chronic hemodialysis patients with unstable, disabling angina in association with severe coronary artery disease involving all three major vessels. Both successfully underwent coronary artery bypass surgery and subsequently experienced dramatic clinical improvement. Principles of management are discussed and it is suggested that hemodialysis patients should not be arbitrarily denied consideration of coronary artery bypass surgery when it is otherwise indicated.</p>","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 1","pages":"33-42"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809103862","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11520115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M A McMillen, F B Cerra, T Baliah, S Anthone, R Anthone
{"title":"Swine influenza vaccination in a dialysis and transplant population.","authors":"M A McMillen, F B Cerra, T Baliah, S Anthone, R Anthone","doi":"10.3109/08860227809080103","DOIUrl":"https://doi.org/10.3109/08860227809080103","url":null,"abstract":"Forty-one adult patients and ten pediatric patients from the Dialysis and Renal Transplant Service were immunized by the subcutaneous route with bivalent influenza vaccine (Wyeth Lab: 1976-1977 formula A/New Jersey/76 and A/Victoria/75). The acquisition of immunity was assessed by hemagglutinin-inhibition titers of antibody to A/NJ/76. Seroconversion was seen in 67% of dialysis patients and 50% of transplant patients. Within the dialysis patient groups (29 patients) there was no correlation with age or length of time on dialysis to the immunization response. The only variables important in seroconversion in the transplant group (22 patients) were age and creatinine clearance. Transplant patients 18-25 years old had a much lower response (12.5%) than did the under 18 (75%) and over 25-year-old patients (90%). All patients with a creatinine clearance greater than 65fl'J/min. responded, whereas only 44% seroconverted with a creatinine clearance less than 65 ml/min. The duration of the transplant, number of r...","PeriodicalId":75998,"journal":{"name":"Journal of dialysis","volume":"2 5-6","pages":"507-22"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/08860227809080103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11583497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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