S. Cagnoni , G. Coppini , M. Rucci , D. Caramella , G. Valli
{"title":"Neural network segmentation of magnetic resonance spin echo images of the brain","authors":"S. Cagnoni , G. Coppini , M. Rucci , D. Caramella , G. Valli","doi":"10.1016/0141-5425(93)90071-6","DOIUrl":"10.1016/0141-5425(93)90071-6","url":null,"abstract":"<div><p>This paper describes a neural network system to segment magnetic resonance (MR) spin echo images of the brain. Our approach relies on the analysis of MR signal decay and on anatomical knowledge; the system processes two early echoes of a standard multislice sequence. Three main subsystems can be distinguished. The first implements a model of MR signal decay; it synthesizes a four-echo multiecho sequence, in order to add images characterized by long echo-times to the input sequence. The second subsystem exploits <em>a priori</em> anatomical knowledge by producing an image, in which pixels belonging to brain parenchyma are highlighted. Such anatomical information allows the following submodule to distinguish biologically different tissues with similar water content, and hence similar appearance, which might produce misclassifications. The grey levels of the reconstructed sequence and the output of the second module are processed by the third subsystem, which performs the segmentation of the sequence. Each pixel is assigned to one of five different tissue classes that can be revealed with brain MR spin echo imaging. With a suitable encoding, a five-level segmented image can then be produced. The system is based on feed-forward networks trained with the back-propagation algorithm; experiments to assess its performance have been carried out on both simulated and clinical images.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 5","pages":"Pages 355-362"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90071-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19219703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An integrated procedure to assess knee-joint kinematics and kinetics during gait using an optoelectric system and standardized X-rays","authors":"J. Li, U.P. Wyss , P.A. Costigan , K.J. Deluzio","doi":"10.1016/0141-5425(93)90076-B","DOIUrl":"10.1016/0141-5425(93)90076-B","url":null,"abstract":"<div><p>This paper describes a 3-D gait analysis system, which combines optoelectric motion tracking and a standardized X-ray procedure, to calculate the net knee-joint forces and moments of a normal subject group during walking. The optoelectric system collects kinematic data from infra-red LED markers placed at selected skin surface locations and projecting probes attached to the lower limb. A standardized X-ray procedure is used to move surface markers into their designated bony landmarks based on individual bone structure, which reduces the error caused by uncertainty of skin-surface marker locations. Based on moved-in marker information, different joint coordinate systems are proposed for kinematic and kinetic analysis of the knee joint. Normalized data of knee angles, net reaction forces and net moments from 35 young, normal subjects are presented.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 5","pages":"Pages 392-400"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90076-B","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19219708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Machetanz, J. Forster, C. Bischoff, B.-U. Meyer, C. Isenberg, B. Conrad
{"title":"PC-based system for an objective quantification of manual movement disability for clinical and scientific purposes","authors":"J. Machetanz, J. Forster, C. Bischoff, B.-U. Meyer, C. Isenberg, B. Conrad","doi":"10.1016/0141-5425(93)90072-7","DOIUrl":"10.1016/0141-5425(93)90072-7","url":null,"abstract":"<div><p>In clinical management and research of movement disorders exact knowledge about the extent of motor impairment is essential. This paper presents a computer program which allows for an objective measurement of manual movement disability. The program was developed for standard hardware and can easily be used in a variety of clinical and research environments. The program runs on MS-DOS computers and uses a Microsoft computer mouse as the only input device. The temporal resolution is 100 Hz, the spatial resolution 400 dots per inch. The user may choose between standard test sets or he may design sets according to his individual needs from a pool of available protocols which includes tracking tasks, ballistic tasks, complex sequential tasks, and finger tapping. All tasks are implemented in a similar way in order to keep the test environment as consistent as possible for the patient. The patient must usually carry out movements which correspond to the movements of a target symbol on the computer screen. This entails the manipulation of a follower symbol, also visible on the computer screen, via the computer mouse. The program itself and the theoretical background of the protocols are described in the paper. Additionally, preliminary results from pilot experiments are presented.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 5","pages":"Pages 363-370"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90072-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19219704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new geometric description of the right ventricle","authors":"F.P. Czegledy, J. Katz","doi":"10.1016/0141-5425(93)90075-A","DOIUrl":"10.1016/0141-5425(93)90075-A","url":null,"abstract":"<div><p>An accurate model of the geometry of the right ventricle would be particularly useful for volume determination by imaging techniques, as well as for mechanical modelling. In this study, a new mathematical model for the right ventricle geometry based on its crescentic cross-sectional shape is proposed and used to calculate its volume in imaged <em>ex-vivo</em> casts. An excellent correlation (<em>r</em> = 0.97) was found between volume as derived from the model and actual volume measured by water displacement.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 5","pages":"Pages 387-391"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90075-A","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19219707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantitative analysis of four EMG amplifiers","authors":"E.J. Perreault, I.W. Hunter, R.E. Kearney","doi":"10.1016/0141-5425(93)90079-E","DOIUrl":"10.1016/0141-5425(93)90079-E","url":null,"abstract":"<div><p>Four typical EMG amplifiers were tested quantitatively to observe the diversity and specificity of available equipment. Gain, phase, common mode rejection ratio (CMRR) and noise characteristics were measured for each device. Various gain and phase responses were observed, each best suited to specific application areas. For all amplifiers, the CMRR was shown to decrease dramatically in the presence of input impedance mismatches of more than 10 kΩ between the two electrodes. Because such impedance mismatches are common on the skin surface, these results indicate that proper skin preparation is required to maximize the noise rejection capabilities of the tested amplifiers.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 5","pages":"Pages 413-419"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90079-E","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19220294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of a concentric water-displacement model lung","authors":"E.M. Williams, L.B. Gale, P.A. Oakley, M.C. Sainsbury, C.E.W. Hahn","doi":"10.1016/0141-5425(93)90080-I","DOIUrl":"10.1016/0141-5425(93)90080-I","url":null,"abstract":"<div><p>Simulation of lung ventilation using a model lung can provide a means of evaluating lung function tests, mathematical models and computer algorithms. We describe a new water-displacement lung model, which can simulate lung volumes up to 3.8 l and tidal volumes up to 1 l. Gas mixing is ensured by using a ring of venturi devices. Model compliance and airways resistance are described.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 5","pages":"Pages 420-424"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90080-I","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19220295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New method for estimating explosive anaerobic leg power","authors":"H.A.M. Al-Nashash , Z.D.M. Al-Kurdi","doi":"10.1016/0141-5425(93)90082-A","DOIUrl":"10.1016/0141-5425(93)90082-A","url":null,"abstract":"<div><p>In this article, a new technique for estimation of explosive anaerobic leg power is proposed. The method relies on accurately measuring the time duration of muscular contraction and the time spent off the ground while performing a vertical jump. Contribution of arms to leg power measurement is minimized by fixing arms at belt line during the test. Results from nine athletes are presented and discussed. A comparison with other methods is also discussed.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 5","pages":"Pages 430-434"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90082-A","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19220297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Precision and accuracy of bone landmarks in characterizing hand and wrist position","authors":"C.F. Small, D.R. Pichora, J.T. Bryant, P.M. Griffiths","doi":"10.1016/0141-5425(93)90073-8","DOIUrl":"10.1016/0141-5425(93)90073-8","url":null,"abstract":"<div><p>Characterization of the motion of the hand and wrist requires reference to the underlying bones which, for three-dimensional analyses, are assumed to be rigid bodies. Stereoradiogrammetric techniques involving the identification of prominent bone landmarks have been used as the standard against which surface markers used for <em>in vivo</em> testing have been evaluated. The precision and accuracy with which the 3D positions of bone landmarks in the hand and wrist could be determined was evaluated in a small inter-observer and inter-cadaver study and compared to the precision and accuracy with which implanted lead markers could be located. A subset of landmarks suitable for evaluating wrist and metacarpal-phalangeal joint motion was identified; the mean precison for identifying these points was better than 1.1 mm in all hand positions with a mean inter-observer accuracy of 2.3 mm. These values show that the average uncertainty in locating bone landmarks is at best roughly twice that for implanted markers.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 5","pages":"Pages 371-378"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90073-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19219705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P.F. Hübsch , J. Middleton , J.S. Rees , P.H. Jacobsen
{"title":"An adaptive finite-element approach for the analysis of dental restorations","authors":"P.F. Hübsch , J. Middleton , J.S. Rees , P.H. Jacobsen","doi":"10.1016/0141-5425(93)90077-C","DOIUrl":"10.1016/0141-5425(93)90077-C","url":null,"abstract":"<div><p>The present paper deals with the problem of stresses generated during the setting process of polymer tooth fillings. A finite element procedure capable of accurately predicting the stresses along an interface between two different materials is presented. Adaptation of the finite element mesh is carried out based on a simple error estimator. The procedure is tested against benchmark problems and then applied to polymer tooth fillings. The results of the study are relevant in understanding and improving the behaviour of dental restorations.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 5","pages":"Pages 401-408"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90077-C","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19219709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Minzly , J. Mizrahi , E. Isakov , Z. Susak , M. Verbeke
{"title":"Computer-controlled portable stimulator for paraplegic patients","authors":"J. Minzly , J. Mizrahi , E. Isakov , Z. Susak , M. Verbeke","doi":"10.1016/0141-5425(93)90012-N","DOIUrl":"10.1016/0141-5425(93)90012-N","url":null,"abstract":"<div><p>A six-channel lightweight, portable and computer-controlled stimulator for the functional activation of paraplegic patients is described. To enable programming of the various functions, the stimulator was designed to work in a remote-control mode hosted by an IBM PC or compatible computer, in addition to its normally used local mode. The stimulus parameters, including current intensity, stimulus frequency and pulse width, are individually adjustable and programmable for each channel. The power source is 12 V 500 mAh<sup>−1</sup>, from 10 rechargeable nickel cadmium batteries, with a run time of 1.5 h for a load of 200 mA in four channels. Various training programmes for the activation of paraplegics in the sitting, standing and walking positions are described. The final design of the stimulator is based on experience gained from 25 patients, treated and evaluated during the course of development. Ongoing work including clinical, biomechanical and physiological studies is carried out to evaluate performance of the activated patients and to optimize stimulation.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 333-338"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90012-N","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19347536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}