{"title":"Volume profiles obtained by a conductimetric method","authors":"M.C. Herrera, M.E. Valentinuzzi, J.M. Olivera","doi":"10.1016/0141-5425(93)90001-F","DOIUrl":"10.1016/0141-5425(93)90001-F","url":null,"abstract":"<div><p>One problem faced by intracardiac conductance volumetry is the non-uniform distribution of the injected current. Salo, in 1989, proposed a method to correct this undesirable effect. The objective here is to test Salo's method in known volumes of simple geometry by obtaining volume profiles. A plastic rod with 15 metallic rings simulated the conductance catheter. Five sections were used for the resistance measurements employing the upper electrode as fixed current source and the lowest one as the shifting source. This is part of Salo's procedure. The source-to-section distance was measured from the moving source to the section (linear definition) or using the equivalent distance concept (Salo's). Thereafter, each sectional resistance set of values was plotted as a function of the inverse of the source-to-section distance (either definition) elevated to an empirical exponent k to obtain the corrected sectional resistance by extrapolation back to zero of the regression line, i.e., a value produced by a source theoretically placed at infinity. In addition, a mathematical analysis was attempted, searching for an optimum k based on minimum volume error. The best volume profiles for two cylinders and a frustum were obtained with k = 2 using the linear definition of distance (errors of − 3.49%, − 1.25% and − 3.65%, respectively). Moreover, the frustum angle was determined within 0.4° (2.7%) of the real value. The theoretical analysis led to an inverse logarithmic relationship between the exponent k and the source-to-section distance. In conclusion: (1) The linear definition of source-to-section distance applying Salo's correction with k = 2 produced the smallest errors, both in volume and angle estimations; (2) there is no optimum k; (3) for very large distance, k tends to a low value (about 0.8); (4) for heart sizes, k = 2.1 can be suggested for all sections.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 267-273"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90001-F","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19346910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microcomputer-based system for automatic analysis of M-mode echocardiograms","authors":"G. Pelle, M.-Y. Belamari","doi":"10.1016/0141-5425(93)90002-G","DOIUrl":"10.1016/0141-5425(93)90002-G","url":null,"abstract":"<div><p>A microcomputer-based system has been developed for automatically analysing M-mode echocardiograms. This system can be used on images directly transferred from an echograph to the microcomputer. To obviate the major disadvantage of echocardiography, its poor signal-to-noise (S/N) level, the system conducts, first, an image restoration based on the quasi-periodicity of cardiac cycles, then border extraction is performed, using methods based on template matching using dynamic cardiac information present in the echocardiograms.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 274-278"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90002-G","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19346911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantification of soft-tissue imbalance in condylar knee arthroplasty","authors":"A. Sambatakakis , S.F. Attfield , G. Newton","doi":"10.1016/0141-5425(93)90013-O","DOIUrl":"10.1016/0141-5425(93)90013-O","url":null,"abstract":"<div><p>Soft-tissue balance has been debated in recent publications in connection with the long-term survival of the ‘condylar-type’ knee prostheses. Present methods of assessment have all assumed that the soft tissues around the knee are inelastic strings. The authors have developed two instruments to quantify soft-tissue imbalance, at the time of the operation, with the assumption that the soft tissues are viscoelastic structures. These two soft-tissue balancing devices were consequently used on 121 patients undergoing condylar knee arthroplasties at the Derbyshire Royal Infirmary and Bretby Hall Orthopaedic Hospital. The first instrument consisted of two flat plates separated by four standard compression springs and provided a qualitative measure of imbalance assuming that the soft tissues were viscoelastic. It was used on 55 patients before being replaced by the quantitative measure of the second instrument. The authors have redefined soft-tissue imbalance, to take into account the viscoelastic nature of the soft tissues, as the resultant trapezoidal geometry of the knee after the bony cuts have been made and when the knee is tensed by equal forces both medially and laterally. The second balancer eliminates the requirement to quantify the individual tensions in the medial and lateral structures by introducing to the system a low-friction, central pivot in the coronal plane. Once the pivot is situated at the centre of the knee, an equilibrium position is achieved where the clockwise and counter-clockwise moments are equal. The tensions exerted by soft tissues can be assumed to be equal and opposite as their moment arms are the same. Imbalance is quantified by the angular displacement of the top plate of the instrument in finding its equilibrium position. This instrument was subsequently used on 66 knees at the Bretby Hall Orthopaedic Hospital.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 339-343"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90013-O","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19347537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accuracy of interface pressure measurement systems","authors":"V. Allen , D.W. Ryan , N. Lomax , A. Murray","doi":"10.1016/0141-5425(93)90014-P","DOIUrl":"10.1016/0141-5425(93)90014-P","url":null,"abstract":"<div><p>Interface pressure measurement is needed to assess beds designed to prevent pressure sores, so it is therefore important to establish the accuracy of interface pressure measuring systems. In this study, the Talley SA500 pressure evaluator (with 28 mm and 100 mm sensor pads), the DIPE (with 100 mm sensor pad), and a water-filled bladder system (with 0.1 ml and 0.3 ml water) were assessed. Measurement errors were evaluated using a loading system with pressures up to 7.4 kPa (55 mm Hg) in steps of 0.9 kPa (6.9 mm Hg). All systems tested over-measured interface pressure, the error being approximately linearly proportional to the loading pressure. The repeatability for a given system was approximately constant. The mean error (± SD) (%) and repeatability (kPa) for the systems were: 28 mm Talley 12 ± 1%, ± 0.07 kPa; 100 mm Talley 15 ± 1%, ± 0.07 kPa; DIPE 27 ± 3%, ± 0.12 kPa; 0.1 ml water bladder 17 ± 1%, ± 0.13 kPa; 0.3 ml water bladder 26 ± 3%, ± 0.07 kPa. Different interfaces affected accuracy markedly, and repeatability was affected when an inhomogeneous interface was used. The study shows that the errors associated with interface pressure measurement systems can be substantial, and can vary from one system to another.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 344-348"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90014-P","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19347538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in oscillometric pulse amplitude envelope with cuff size: implications for blood pressure measurement criteria and cuff size selection","authors":"K.-G. Ng, C.F. Small","doi":"10.1016/0141-5425(93)90003-H","DOIUrl":"10.1016/0141-5425(93)90003-H","url":null,"abstract":"<div><p>Oscillometric blood pressures are derived from the amplitude envelope of oscillometric pulses generated in an occlusive cuff during cuff inflation or deflation; one factor which will affect the characteristics of these pulses is the size of the cuff bladder. Because limiting values are stipulated in recommendations and standards for bladder sizes, there is a wide variety of acceptable cuff sizes for any particular application. An experimental and theoretical study was undertaken to show the dependence of oscillometric blood pressures on bladder size. Actual cuff-arm compliance data were obtained from two subjects for two cuffs of different bladder size. Theoretical analysis was then applied to the data to predict the effects of different bladder sizes on the characteristics of the pulses. The results show that cuff-arm compliance and bladder size interact to affect the pulse amplitude and hence oscillometric blood pressure determination. These results suggest that blood pressures obtained using the oscillometric method may vary depending on cuff size, and in particular that replacement cuffs for oscillometric non-invasive blood pressure monitors should be chosen carefully.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 279-282"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90003-H","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19346912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dynamic model of the bronchial tree","authors":"I. Ginzburg , D. Elad","doi":"10.1016/0141-5425(93)90004-I","DOIUrl":"10.1016/0141-5425(93)90004-I","url":null,"abstract":"<div><p>We present a distributed model of the bronchial tree which simulates the global dynamic characteristics of the lung. Local mechanical characteristics of each airway are represented by RCL circuits and parameters of the electrical components are determined from local physiological data. The bronchi geometry is described by Weibel's symmetric model, the flow in each airway is assumed laminar and mixing effects at the bifurcations are neglected; the transpulmonary pressure is assumed to be sinusoidal. In simulations of quiet breathing the resistance to airflow is found to be dominant, the flow amplitude decreasing as breathing frequency increases, but remaining almost constant in all the generations. Simulations of ventilation through obstructed lungs show frequency dependence of the dynamic characteristics in very compliant lungs. The global resistance to airflow and the dynamic compliance of the bronchi decrease as the forced oscillation frequency increases in a pattern similar to <em>in vivo</em> measurements in diseased lungs. This may be an outcome of the RCL properties of the network rather than due to uneven distribution of mechanical properties of the lung.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 283-288"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90004-I","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19346913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stress analysis of endosseous implants using the Boundary Integral Equation (BIE) method","authors":"L.A. Wolfe","doi":"10.1016/0141-5425(93)90009-N","DOIUrl":"10.1016/0141-5425(93)90009-N","url":null,"abstract":"<div><p>The Boundary Integral Equation (BIE) method for modelling mathematically an endosseous implant within its bony surroundings is described in this study. The results are compared to those calculated by Finite Element Analysis (FEA), and the following conclusions drawn: both FEA and BIE are able to provide stress analyses of the dental implant situation and give similar numerical values of stresses and strains at the implant-bone interfaces. The BIE method does not produce a pictorial representation of the calculated stresses in the form of stress contours, as this is not applicable to boundary investigations. It is easier to alter the outline of the implant with line elements than with solid elements; therefore slight alterations in the outline form of an implant are easy to investigate with regard to their resultant interfacial stress levels. The BIE method is simpler to use than FEA, but little software is commercially available. The aim of the study was to determine whether future developments in this field could be useful in the stress analysis of endosseous implants.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 319-323"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90009-N","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19347533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mathematical modelling of the enteric nervous network II: facilitation and inhibition of the cholinergic transmission","authors":"R.N Miftakhov, D.L Wingate","doi":"10.1016/0141-5425(93)90008-M","DOIUrl":"10.1016/0141-5425(93)90008-M","url":null,"abstract":"<div><p>The pharmacokinetic responses of the cholinergic enteric neurone to treatment with acetylcholinesterases, tetrodotoxin, some chloride salts of divalent cations, botulinum toxin, β -bungarotoxin and changes in the concentration of calcium ions in the external medium and repetitive stimulation are presented. The numerical results obtained reproduce quantitatively the effects of toxins and salts of divalent cations acting at different levels of acetylcholine release from the nerve-terminal. The addition of cholinergic agonists potentiates the action of acetylcholine and increases the amplitude of the generated excitatory postsynaptic potential. A decrease in the concentration of extracellular Ca<sup>2+</sup> ions reduces the amplitude of the excitatory postsynaptic potential and significantly increases synnaptic transmision time. The effect of tetrodotoxin is the blockade propagation of the action potential along the nerve axon and, as a consequence, acetylcholine release from the vesicular store. All these effects have been shown to be dose-dependent. The repetitive stimulation of the neurone reproduces the effects of accumulation and potentiation. The possible applications of the model for the analysis of the enteric nervous system function are discussed.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 311-318"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90008-M","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19381442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stresses at the meniscofemoral joint: elastostatic investigations on the applicability of interface elements","authors":"M. Lengsfeld","doi":"10.1016/0141-5425(93)90010-V","DOIUrl":"10.1016/0141-5425(93)90010-V","url":null,"abstract":"<div><p>Stress distributions at the meniscofemoral joint were analysed and the applicability of nonlinear interface elements in a finite element model (FEM) were tested. Centred and 70% off-centre load cases with a complete, a partially removed or a totally removed medial meniscus were evaluated in two dimensions. Interface width was assumed to increase linearly from almost zero to 1 mm at the inner and outer border of the femoral condyles. Maximum interface forces were found at the centre of the condyles, decreasing to zero at the peripherical and intercondylar femoral border. Simulation data concerning a removed medial meniscus or medial 70% off-centre load with complete meniscus indicated higher medial contact forces in the first case. A decrease in the elastic modulus of the articular surface tissues caused two small force transfer peaks (femoral centre and intercondylar border), which were strongly influenced by the predefined gap width.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 324-328"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90010-V","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19347534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Repeatability of subject/bed interface pressure measurements","authors":"V. Allen , D.W. Ryan , A. Murray","doi":"10.1016/0141-5425(93)90011-M","DOIUrl":"10.1016/0141-5425(93)90011-M","url":null,"abstract":"<div><p>The repeatability of a technique for measuring interface pressures has been assessed. Pressure was measured using a Talley SA500 Pressure Evaluator under six anatomical sites (occiput, scapula, elbow, sacrum, buttock, and heel) of six healthy subjects lying supine on a Clinifloat mattress (trademark, SSI). For each site of each subject, four repeat readings were taken per day on four separate days. Mean pressures varied significantly between subjects (<em>p</em> < 0.02), though differences in mean pressures between sites were greater. Pressure was not significantly related to subject mass. The overall repeatability of the technique was ± 0.77 kPa (± 5.8 mm Hg) which was much smaller than the range of pressures found under different sites (2.72 kPa or 20.4 mm Hg at the sacrum to 9.00 kPa or 67.5 mm Hg at the heel). Repeatability varied from site to site, from ± 0.47 kPa (± 3.5 mm Hg) at the buttocks to ± 1.20 kPa (± 9.0 mm Hg) at the heel. Measurements were found to vary significantly more between days than between repeats on the same day (<em>p</em> < 0.02).</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 4","pages":"Pages 329-332"},"PeriodicalIF":0.0,"publicationDate":"1993-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90011-M","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19347535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}