American Journal of Otolaryngology最新文献

{"title":"Characterizing radiation-related laryngotracheal stenosis","authors":"Natalia Queenan ,&nbsp;Jay Trivedi ,&nbsp;Dylan Bertoni ,&nbsp;Sana H. Siddiqui ,&nbsp;Austin Yap ,&nbsp;Kathleen M. Tibbetts","doi":"10.1016/j.amjoto.2025.104643","DOIUrl":"10.1016/j.amjoto.2025.104643","url":null,"abstract":"<div><h3>Background</h3><div>Radiation-related laryngotracheal stenosis (RLTS) develops due to fibrosis of the airway after radiotherapy. We aim to characterize the presentation, management, and outcomes of patients with RLTS and compare these to patients with iatrogenic laryngotracheal stenosis (ILTS).</div></div><div><h3>Methods</h3><div>In a single-center retrospective cohort study, patients diagnosed with RLTS between 2017 and 2022 were identified. Demographic data, risk factors, cancer history and treatment, presentation of stenosis, primary stenosis intervention, and outcomes were extracted. Patients were compared to a cohort of patients with ILTS and no history of radiation therapy. Data were analyzed using Fisher's Exact Tests and paired <em>t</em>-tests.</div></div><div><h3>Results</h3><div>Seven patients with head and neck malignancies (six laryngeal, one thyroid) who developed RLTS after radiation therapy were included. One patient had supraglottic stenosis, three glottic, five subglottic, and two tracheal. Mean time to diagnosis of RLTS from initiation of radiation was 14.8 months (range: 2–46 months). Five patients were treated with laser ablation of stenosis. The patients with RLTS were compared to a cohort of 105 patients with ILTS. Patients with RLTS were less likely to have obesity (Odds Ratio (OR) = 0.06; 95 % Confidence Interval (CI) = 0.003–0.99) and more likely to have coronary vascular disease (OR = 5.5; 95 % CI = 1.04–29.6). No significant differences in interventions or outcomes were found.</div></div><div><h3>Conclusions</h3><div>Risk factors for RLTS and ILTS differ, but management strategies and treatment outcomes are comparable.</div><div>Level of evidence: IV</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 4","pages":"Article 104643"},"PeriodicalIF":1.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143887056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of vascularization patterns in juvenile Angiofibroma and the impact of preoperative embolization on surgical excision","authors":"Hon Minh Hao Nguyen ,&nbsp;Minh Tran Quang Le ,&nbsp;Hai Thanh Nguyen ,&nbsp;Hong Viet Tran ,&nbsp;Luan Viet Tran","doi":"10.1016/j.amjoto.2025.104632","DOIUrl":"10.1016/j.amjoto.2025.104632","url":null,"abstract":"<div><h3>Background</h3><div>Juvenile nasopharyngeal angiofibroma (JNA) is a rare, highly vascular tumor posing a significant challenge for endoscopic excision due to excessive intraoperative bleeding. Exploring feeding vessels and preoperative embolization could reduce intraoperative blood loss and improve surgical outcomes for JNA. This study investigates the vascularization patterns of JNA and the impact of preoperative embolization on surgical excision.</div></div><div><h3>Methods</h3><div>This was a descriptive cross-sectional study of 30 histopathologically confirmed JNA patients who underwent preoperative embolization followed by endoscopic surgical excision from January 2019 to May 2023 at Ear Nose Throat Hospital of Ho Chi Minh City. The distribution of vascular supply of tumors, as well as the role of preoperative embolization, were analyzed.</div></div><div><h3>Results</h3><div>Most tumors received exclusive blood supply from the internal maxillary artery (IMA) accounting for 50%, with 20% of cases being supplied by bilateral IMAs. A combined supply pattern involving the IMA and other external carotid artery branches was observed in 26.6%. Three complex cases (10%) received blood from the internal carotid artery (ICA). Embolization was performed at branches originating from the external carotid artery (ECA) but not from the ICA to avoid complications. All patients achieved complete endoscopic JNA excision. The average intraoperative blood loss was 608 mL (range: 100 mL - 3000 mL), and the average Boezaart score was 2.63. No major surgical complications occurred in the perioperative period. Significant differences in blood loss were observed among different UPMC tumor stages (<em>p</em> &lt; 0.001) and tumor sizes (<em>p</em> = 0.008). Advanced-stage tumors were more likely to have an ICA blood supply (<em>p</em> = 0.038).</div></div><div><h3>Conclusion</h3><div>Understanding the vascularization patterns of juvenile angiofibroma and the role of preoperative embolization can facilitate endoscopic excision of these tumors.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 3","pages":"Article 104632"},"PeriodicalIF":1.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extra-capsular nodal extension after surgical resection for HPV-positive oropharyngeal Cancer: Adjuvant radiation versus chemoradiation","authors":"Allen M. Chen ,&nbsp;Tjoson Tjoa ,&nbsp;William B. Armstrong","doi":"10.1016/j.amjoto.2025.104639","DOIUrl":"10.1016/j.amjoto.2025.104639","url":null,"abstract":"<div><h3>Purpose</h3><div>The prognostic significance of extra-capsular nodal extension (ECE) after surgical resection for human papillomavirus (HPV)-positive oropharyngeal cancer is controversial, and the optimal choice of adjuvant therapy is uncertain in this setting.</div></div><div><h3>Methods and materials</h3><div>A review of institutional databases identified a total of 63 patients with pathological evidence of ECE in at least 1 cervical lymph node after transoral robotic surgery and neck dissection for HPV-positive squamous cell carcinoma of the oropharynx. Clinical outcomes were compared based on whether patients received adjuvant radiation (20 patients) or chemoradiation (43 patients). The Kaplan Meier method was used to determine survival statistics with comparisons between groups conducted with the log-rank test.</div></div><div><h3>Results</h3><div>With a median follow-up of 50 months (range, 6 to 110 months), the 3-year overall survival for the entire population was 87 %. No significant difference was observed between patients treated by adjuvant radiation and chemoradiation with respect to 3-year overall survival (86 % versus 87 %, <em>p</em> = 0.45), local-regional control (91 % vs. 90 %, <em>p</em> = 0.71), and progression-free survival (83 % vs. 85 %, <em>p</em> = 0.57). Exploratory subset analysis of competing variables failed to identify any group in which the addition of chemotherapy to radiation improved outcome.</div></div><div><h3>Conclusions</h3><div>While the presence of ECE after surgical resection has historically been considered an indication for the use of concurrent chemoradiation in the adjuvant setting, these data suggest that this paradigm should be re-evaluated in the setting of HPV-positive oropharyngeal cancer.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 4","pages":"Article 104639"},"PeriodicalIF":1.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143886961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress of anti-IGE treatment for allergic rhinitis","authors":"Rongrong Lv ,&nbsp;Jie Shan ,&nbsp;Anchi Sun ,&nbsp;Zhiwei Xing ,&nbsp;Qun Xu ,&nbsp;Qianqian Shao ,&nbsp;Hui Li","doi":"10.1016/j.amjoto.2025.104646","DOIUrl":"10.1016/j.amjoto.2025.104646","url":null,"abstract":"<div><h3>Background</h3><div>Allergic rhinitis (AR) is an inflammatory reaction of the nasal mainly mediated by Immunoglobulin E(IgE). It is one of the most common chronic diseases in the world. Patients with nasal discomfort, persistent nasal itching, sneezing, runny nose and so on as the main symptoms, it is a refractory allergic disease, will seriously reduce the quality of life of patients.</div></div><div><h3>Objective</h3><div>At present, the treatment of patients with allergic rhinitis is mainly to avoid contact with allergens, drug treatment and desensitization treatment. The serum IgE level of most patients is significantly increased. By introducing monoclonal antibodies into the gene-expression environment of IgE, the levels of free IgE can be effectively suppressed, resulting in a significant reduction in the incidence of AR. Therefore, this article will explore the mechanism and clinical application of this new anti-IgE drug, omalizumab.</div></div><div><h3>Conclusion</h3><div>Omalizumab can significantly relieve the condition of AR patients and reduce the dosage of corticosteroids and antihistamines, but its long-term efficacy and safety need further observation and analysis. Before use, the patient's status should be confirmed and the potential risks should be discussed with the patient in advance.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 3","pages":"Article 104646"},"PeriodicalIF":1.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of nasal surgery with olfactory function among older adults","authors":"Khamis T. Suleiman ,&nbsp;Richard G. Chiu ,&nbsp;Sharmilee M. Nyenhuis ,&nbsp;Kamal Eldeirawi ,&nbsp;Victoria S. Lee","doi":"10.1016/j.amjoto.2025.104638","DOIUrl":"10.1016/j.amjoto.2025.104638","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Olfactory Dysfunction (OD) is a prevalent condition that commonly presents in the older adult population. Various factors have been shown to contribute to OD, such as neurodegenerative disease, older age, and smoking status; however, the influence of nasal surgery on olfactory function is not well delineated. This study seeks to explore the potential effect of nose surgery on olfactory function.</div></div><div><h3>Methods</h3><div>This cross-sectional study was conducted on data for 2285 adults from Round 1 of the National Social Life, Health, and Aging Project (NSHAP), a nationally representative sample of US older adults. The 5-item Sniffin’ Sticks test was used to define olfactory function: correctly identifying <span><math><mo>≥</mo></math></span>4 odors indicated normal olfactory function, while correctly identifying 0–3 odors was considered OD Associations between prior nasal surgery and OD were assessed using multivariable logistic regression, and adjusted odds ratios (OR) were calculated. Analyses were weighted using NSHAP-provided person-level weights to account for sampling design.</div></div><div><h3>Results</h3><div>OD was present in 18.4 % of adults. The weighted average age was 67.1 ± 7.2 years among those with normal olfaction and 70.9 ± 7.9 years for those with OD. Of adults with OD, 9.8 % had a prior nasal surgery as compared to 8.1 % of those with normal olfaction, although the difference was not statistically significant. After adjusting for age, gender, race, education, prior stroke, dementia, and self-reported mental health, prior nasal surgery was not significantly associated with OD (OR: 1.14; 95 % CI: 0.77–1.70).</div></div><div><h3>Conclusion</h3><div>Prior nasal surgery was not associated with OD after controlling for covariates. While this study does provide unique insight into the relationship between nasal surgery and OD in nationally representative cohort of older adults, it was limited since the dataset utilized did not contain information on the specific surgery that participants underwent. Therefore, further research with more detailed information on the types of nasal surgeries and sinonasal conditions prior to surgery would further help elucidate the relationship between and nasal surgery and OD.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 3","pages":"Article 104638"},"PeriodicalIF":1.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143868670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reoperation for hematoma in patients on perioperative antithrombotic drugs underwent thyroidectomy","authors":"Bassam Abboud ,&nbsp;Christopher Abboud ,&nbsp;Mayssam Meouche","doi":"10.1016/j.amjoto.2025.104636","DOIUrl":"10.1016/j.amjoto.2025.104636","url":null,"abstract":"<div><h3>Backgrounds</h3><div>Evaluate the risk of reoperation for postoperative hematoma (POH) in patients on antithrombotic conditions underwent thyroidectomy.</div></div><div><h3>Methods</h3><div>Three groups: Groups 1, 2, and 3 included thyroidectomy without treatment, under antiplatelet and anticoagulation drugs, respectively. Occurrence of POH identified 2 groups: hematoma (Group A) and no hematoma (Group B).</div></div><div><h3>Results</h3><div>The overall incidence of POH was 6 %(reoperation 0.1 %, conservative 5.9 %). 83 % of the reoperation for POH occurred within the first 24 h. Antiplatelet and anticoagulant drugs were associated with a 3.4 and 5.2 increased odds of POH respectively. Hyperthyroidism, substernal goiter, hypertension, and antithrombotic drugs were present in 32 % and 7 %, 33 % and 11 %, 52 % and 27 %, and 30 % and 9 % of patients in groups A and B respectively. Reoperation was necessary in 0.08 %, 0.23 %, and 1 % of patients in groups 1, 2, and 3 respectively.</div></div><div><h3>Conclusions</h3><div>Patients underwent thyroidectomy under antithrombotic drugs are at much higher risk for reoperation for POH.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 4","pages":"Article 104636"},"PeriodicalIF":1.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of ChatGPT for patient education involving HPV-associated oropharyngeal cancer","authors":"Terral A. Patel ,&nbsp;Gillian Michaelson ,&nbsp;Zoey Morton ,&nbsp;Alexandria Harris ,&nbsp;Brandon Smith ,&nbsp;Richard Bourguillon ,&nbsp;Eric Wu ,&nbsp;Arturo Eguia ,&nbsp;Jessica H. Maxwell","doi":"10.1016/j.amjoto.2025.104642","DOIUrl":"10.1016/j.amjoto.2025.104642","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to investigate the ability of ChatGPT to generate reliably accurate responses to patient-based queries specifically regarding oropharyngeal squamous cell carcinoma (OPSCC) of the head and neck.</div></div><div><h3>Study design</h3><div>Retrospective review of published abstracts.</div></div><div><h3>Setting</h3><div>Publicly available generative artificial intelligence.</div></div><div><h3>Methods</h3><div>ChatGPT 3.5 (May 2024) was queried with a set of 30 questions pertaining to HPV-associated oropharyngeal cancer that the average patient may ask. This set of questions was queried a total of four times preceded by a different prompt. The answer prompts for each question set were reviewed and graded on a four-part Likert scale. A Flesch-Kincaid reading level was also calculated for each prompt.</div></div><div><h3>Results</h3><div>For all answer prompts (<em>n</em> = 120), 6.6 % were graded as mostly inaccurate, 7.5 % were graded as minorly inaccurate, 41.7 % were graded as accurate, and 44.2 % were graded as accurate and helpful. The average Flesch-Kincaid reading grade level was lowest for the responses without any prompt (11.77). Understandably, the highest grade levels were found in the physician-friend prompt (12.97). Of the 30 references, 25 (83.3 %) were found to be authentic published studies. Of the 25 authentic references, the answers accurately cited information found within the original source for 14 of the references (56 %).</div></div><div><h3>Conclusion</h3><div>ChatGPT was able to produce relatively accurate responses to example patient questions, but there was a high rate of false references. In addition, the reading level of the answer prompts was well above the Centers for Disease Control and Prevention (CDC) recommendations for the average patient.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 4","pages":"Article 104642"},"PeriodicalIF":1.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143863574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Head and neck cancer trends in Ohio: Examining temporal, anatomical, and geospatial patterns across Appalachian and non-Appalachian regions","authors":"Samuel Borgemenke ,&nbsp;Milena Fabry ,&nbsp;Elizabeth A. Beverly","doi":"10.1016/j.amjoto.2025.104634","DOIUrl":"10.1016/j.amjoto.2025.104634","url":null,"abstract":"<div><h3>Purpose</h3><div>Head and neck cancer (HNC) is the seventh most common type of cancer worldwide. Compared to the rest of the United States, Appalachia has higher incidence rates of HNC. The purpose of this project is to examine the temporal, anatomical, and geospatial variances in head and neck cancers across Ohio, focusing on disparities between Appalachian and non-Appalachian regions.</div></div><div><h3>Methods</h3><div>Data was sourced from the Center for Disease Control and Prevention and Surveillance, Epidemiology, and End Results database. The incidence and mortality rates of HNC across Ohio were identified and sub classified based on anatomical site. Social determinants of health and environmental factors affecting HNC raters were compared between Appalachian and non-Appalachian regions.</div></div><div><h3>Results</h3><div>The incidence (<em>R</em> = 0.9, <em>P</em> &lt; 0.01) and mortality (<em>R</em> = 0.8, <em>P</em> &lt; 0.01) of head and neck cancer increased significantly from 1999 to 2021 and demonstrated a relationship with mortality (<em>R</em> = 0.3, <em>P</em> &lt; 0.01). Adult smoking (<em>R</em> = 0.5, <em>P</em> &lt; 0.001), obesity (R = 0.5, <em>P</em> &lt; 0.001), and dentist rates (R = 0.3, <em>P</em> &lt; 0.01) were associated with HNC rates. Mean mortality was significantly higher for Appalachian (mean = 10.7, SD = 2.6) than non-Appalachian (mean = 8.6, SD = 2.4) regions (<em>P</em> &lt; 0.01) communities.</div></div><div><h3>Conclusion</h3><div>These findings emphasize the importance of addressing modifiable risk factors through smoking cessation, weight management, and dietary improvements. The difference in mortality between Appalachian and non-Appalachian regions underscores the role of geographic and socioeconomic disparities in shaping health outcomes across Ohio.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 4","pages":"Article 104634"},"PeriodicalIF":1.8,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Goodbye Dr. Google, hello Dr. ChatGPT: Advancing a new frontier for ENT medical information online","authors":"Richard J. Lu ,&nbsp;Babak Azizzadeh","doi":"10.1016/j.amjoto.2025.104618","DOIUrl":"10.1016/j.amjoto.2025.104618","url":null,"abstract":"","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 3","pages":"Article 104618"},"PeriodicalIF":1.8,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of ipsilateral false vocal fold resection on swallowing following transoral laser cordectomies — A fibreoptic endoscopic evaluation of swallowing study","authors":"A. Burián ,&nbsp;K. Smatanová ,&nbsp;T. Bocskai ,&nbsp;János Girán ,&nbsp;I. Szanyi","doi":"10.1016/j.amjoto.2025.104622","DOIUrl":"10.1016/j.amjoto.2025.104622","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate early and late impact of false vocal fold removal (vestibulectomy) on swallowing using FEES following type III, IV and V transoral laser cordectomies (TLC).</div></div><div><h3>Material and method</h3><div>Fifteen transorally resectable glottic cancers (10 T1a, 2 T1b, 2 T2, 1 selected T3) necessitating TLC with vestibulectomy were included. All participants underwent TLC in the investigation period. FEES was performed preoperatively and in the early and late postoperative period establishing modified penetration-aspiration scale (mPAS) and pharyngeal residue severity scale (PRSS) to statistically assess possible differences among the investigated timepoints. Laryngeal preservation and local recurrence were also noted.</div></div><div><h3>Results</h3><div>2 type III, 9 type IV, 2 type Va and 2 type Vd cordectomies were performed. Early postoperative mPASs changed significantly compared to preoperative status (<em>p</em> = 0.046). Difference between early and late postoperative mPASs was also significant (<em>p</em> = 0.046). There was no difference between preoperative and late postoperative mPASs (<em>p</em> = 1.0). Regarding pharyngeal residue, significant changes were noted in the early postoperative period compared to preoperative values (<em>p</em> = 0.002). Regarding late postoperative PRSSs, statistically significant decline was found compared to early postoperative scores (<em>p</em> = 0.004). No remarkable difference was found between preoperative and late postoperative PRSSs (<em>p</em> = 0.317). Laryngeal preservation failed in only one case due to recurrence.</div></div><div><h3>Conclusion</h3><div>In our serie, ipsilateral vestibulectomy during TLC did not deteriorate swallowing in the long term neither by increased pharyngeal residue nor by increased aspiration risk. Investigation of cases without co-morbidities may further confirm our observations. Nevertheless, TLC provided excellent laryngeal preservation.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 3","pages":"Article 104622"},"PeriodicalIF":1.8,"publicationDate":"2025-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}