American Journal of Ophthalmology Case Reports最新文献_第4页

Surgical management of two cases with macular exudation from retinal macroaneurysms refractory to focal photocoagulation 视网膜大动脉瘤黄斑渗出灶性光凝治疗难治性的手术治疗2例

American Journal of Ophthalmology Case Reports Pub Date : 2025-08-26 DOI: 10.1016/j.ajoc.2025.102414

Yuta Usami , Masayo Kimura , Atsuki Matsumoto , Aoi Kominami , Hiroshi Morita , Tsutomu Yasukawa

{"title":"Surgical management of two cases with macular exudation from retinal macroaneurysms refractory to focal photocoagulation","authors":"Yuta Usami , Masayo Kimura , Atsuki Matsumoto , Aoi Kominami , Hiroshi Morita , Tsutomu Yasukawa","doi":"10.1016/j.ajoc.2025.102414","DOIUrl":"10.1016/j.ajoc.2025.102414","url":null,"abstract":"<div><h3>Purpose</h3><div>To report two cases of macular exudations resulting from retinal arterial macroaneurysms (MaAs) refractory to focal photocoagulations that were treated with a new surgical technique including subretinal balanced saline solution (BSS) injection to dilute lipid-rich subretinal fluid (SRF) and facilitate absorption of the SRF, intentional retinal hole formation to direct SRF into the vitreous cavity, and laser photocoagulation posterior to the MaAs to prevent intraretinal fluid and SRF from reaching the fovea.</div></div><div><h3>Observations</h3><div>A 70-year-old man with macular edema (ME) refractory to anti-vascular endothelial growth factor (VEGF) therapy was referred to our hospital. Fundus examination showed retinal arterial MaAs and hard exudations. He underwent laser photocoagulation, sub-Tenon injections of triamcinolone acetonide (STTA), and anti-VEGF therapies; the ME recured despite all treatments. Subretinal lipid-rich exudatoins from retinal arterial MaAs involved the macula, which led to severe vision loss. Therefore, vitrectomy with the new technique was planned to flush out the lipid-rich SRF and prevent new exudations from reaching the macula. Postoperatively, the SRF resolved completely and the ME has not reccured until 59 months postoperatively at his latest visit. The second patient was a 77-year-old woman with an epiretinal membrane and ME with sarcoidosis. She underwent anti-VEGF therapy, STTA injection, and focal laser photocoagulation. The vision-threatening ME persisted. She underwent vitrectomy with the new technique, and the macular exudation resolved promptly. The ME has not recurred 27 months postoperatively.</div></div><div><h3>Conclusions</h3><div>Vitrectomy with this technique may be considered in cases with vision-threatening ME due to retinal MaAs resistant to combined multiple conventional treatments.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"39 ","pages":"Article 102414"},"PeriodicalIF":0.0,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144907751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suture stent insertion into an over draining tube shunt lumen via single paracentesis 缝合线支架通过单次穿刺插入过引流管分流管腔

American Journal of Ophthalmology Case Reports Pub Date : 2025-08-23 DOI: 10.1016/j.ajoc.2025.102412

Sukriti Mohan , Jessie Wang , Jonathan Eisengart , Mary Qiu

引用次数: 0

Chronic Progressive External Ophthalmoplegia (CPEO): Rehabilitation utilizing scleral contact lenses 慢性进行性外眼肌麻痹（CPEO）：巩膜隐形眼镜的康复

American Journal of Ophthalmology Case Reports Pub Date : 2025-08-21 DOI: 10.1016/j.ajoc.2025.102411

Nir Erdinest , Nadav Shemesh , Naomi London , David Landau , Itay Lavy

{"title":"Chronic Progressive External Ophthalmoplegia (CPEO): Rehabilitation utilizing scleral contact lenses","authors":"Nir Erdinest , Nadav Shemesh , Naomi London , David Landau , Itay Lavy","doi":"10.1016/j.ajoc.2025.102411","DOIUrl":"10.1016/j.ajoc.2025.102411","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate the use of scleral contact lenses in managing symptoms of Chronic Progressive External Ophthalmoplegia (CPEO) after failed conventional treatments.</div></div><div><h3>Observations</h3><div>A 69-year-old female with CPEO presented with persistent discomfort and blurry vision despite artificial tears and ointment treatments. Diagnosed with blepharoptosis, myogenic ptosis, dry eye syndrome, dermatochalasis, and lagophthalmos, she showed no improvement post-prolene frontalis suspension surgery. Scleral lenses provided immediate ptosis relief, improving spectacle-corrected visual acuity from 6/12 (−3) and 6/15 (−2) to 6/6 (−1) and 6/7.5 (−2) in the right and left eyes, respectively. Prior to scleral lens fitting, ocular surface staining showed an Oxford score of 3.0 in both eyes, which improved to <1 and remained stable through the four-year follow-up. The OSDI score decreased from 95.83 to 4.17, with sustained symptom relief and stable visual clarity reported throughout, without complications.</div></div><div><h3>Conclusions and importance</h3><div>Scleral contact lenses provided significant relief from ptosis, markedly improved visual acuity, substantially reduced ocular surface damage, and nearly eliminated subjective dry eye symptoms in this complex CPEO case. These lenses are recommended as a primary therapeutic option for CPEO patients with ocular surface complications when conventional treatments are ineffective, offering sustained symptom relief and enhanced visual function.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"39 ","pages":"Article 102411"},"PeriodicalIF":0.0,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144893109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-traumatic myelin oligodendrocyte glycoprotein antibody optic neuritis: A case report 外伤性髓鞘少突胶质细胞糖蛋白抗体视神经炎1例

American Journal of Ophthalmology Case Reports Pub Date : 2025-08-20 DOI: 10.1016/j.ajoc.2025.102409

Saif A. Hamdan , Jamie A. Nassur , Sarah Thornton

{"title":"Post-traumatic myelin oligodendrocyte glycoprotein antibody optic neuritis: A case report","authors":"Saif A. Hamdan , Jamie A. Nassur , Sarah Thornton","doi":"10.1016/j.ajoc.2025.102409","DOIUrl":"10.1016/j.ajoc.2025.102409","url":null,"abstract":"<div><h3>Purpose</h3><div>Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) has recently been distinguished as its own disease entity separate from other demyelinating diseases. This case report highlights the possible association of orbital trauma with the development of MOG antibody (MOG-IgG) optic neuritis.</div></div><div><h3>Observations</h3><div>A 31-year-old male with no significant ocular history presented with blurry vision in the right eye four weeks after a motorcycle crash. Right eye examination was notable for a significant decrease in visual acuity with a relative afferent pupillary defect and circumferential disc elevation on fundoscopy. An extensive workup, including imaging and serology, revealed optic neuritis with a positive MOG-IgG antibody titer. The patient was treated with intravenous steroids followed by an oral taper, with near-complete resolution of his symptoms.</div></div><div><h3>Conclusions and importance</h3><div>MOG antibody-related optic neuritis should be considered in patients presenting with painful vision loss after trauma, as early recognition and treatment can lead to favorable outcomes.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"39 ","pages":"Article 102409"},"PeriodicalIF":0.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful treatment of stellate multiform amelanotic choroidopathy with photodynamic therapy: A case report 光动力疗法成功治疗星状多形态无色变性脉络膜病1例

American Journal of Ophthalmology Case Reports Pub Date : 2025-08-19 DOI: 10.1016/j.ajoc.2025.102410

Luuk van Gorcom , Mehmet Ikinci , Sankha Amarakoon

{"title":"Successful treatment of stellate multiform amelanotic choroidopathy with photodynamic therapy: A case report","authors":"Luuk van Gorcom , Mehmet Ikinci , Sankha Amarakoon","doi":"10.1016/j.ajoc.2025.102410","DOIUrl":"10.1016/j.ajoc.2025.102410","url":null,"abstract":"<div><h3>Purpose</h3><div>To report a case of stellate multiform amelanotic choroidopathy (SMACH) with focal hyperfluorescence on indocyanine green angiography (ICGA), successfully treated with photodynamic therapy (PDT).</div></div><div><h3>Observations</h3><div>An 18-year-old male presented with subretinal fluid (SRF) overlying an irregular lesion in the inner choroid. A diagnosis of probable idiopathic macular neovascularization was made; treatment with intravitreal injections (IVIs) of anti-vascular endothelial growth factor (VEGF) agents showed no effect. The diagnosis was later revised to SMACH due to distinctive features on optical coherence tomography (OCT) and ICGA. Typically, no focal leakage is observed on ICGA in SMACH, and no successful treatment has been previously described. However, our case presented with focal leakage on ICGA, and treatment with full-dose PDT led to complete resolution of SRF.</div></div><div><h3>Conclusions and importance</h3><div>Diagnosing and treating SMACH can be challenging. No effective treatment has been reported to date. We describe a case with focal leakage on ICGA successfully treated with full-dose PDT. We suggest full-dose PDT as the first-line treatment of SMACH with associated focal leakage on ICGA.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"39 ","pages":"Article 102410"},"PeriodicalIF":0.0,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144887584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early-onset macular drusen, a monogenic form of age-related macular degeneration 早发性黄斑变性，一种年龄相关性黄斑变性的单基因形式

American Journal of Ophthalmology Case Reports Pub Date : 2025-08-08 DOI: 10.1016/j.ajoc.2025.102408

Lisa M. George , Mathur Ranjana , Mathieu Quinodoz , Rachael W.C. Tang , Weng Khong Lim , Noa G. Gilhar , Saadia Z. Farooqui , Carlo Rivolta , Beau J. Fenner

引用次数: 0

Iris cerclage with goniosynechialysis and canalicular stent for neovascular angle closure glaucoma 虹膜环扎术联合角膜联合小管支架治疗新生血管性闭角型青光眼

American Journal of Ophthalmology Case Reports Pub Date : 2025-08-05 DOI: 10.1016/j.ajoc.2025.102393

Faria Mahjabin , Peter E. Libre

引用次数: 0

Use of a Kerato-lenticule extraction (KLEx) lenticule to protect the lens during pupilloplasty: a novel technique in phakic eyes 在瞳孔成形术中使用角膜-晶状体提取（KLEx）晶状体来保护晶状体：一种用于有晶状体眼的新技术

American Journal of Ophthalmology Case Reports Pub Date : 2025-08-05 DOI: 10.1016/j.ajoc.2025.102403

Aylin Tetik MD, Guillaume Boutillier MD, David Toubeau, Fanny Chaventre, Anaïs Vautier MD, Julie Gueudry MD, PhD, Marc Muraine MD, PhD

{"title":"Use of a Kerato-lenticule extraction (KLEx) lenticule to protect the lens during pupilloplasty: a novel technique in phakic eyes","authors":"Aylin Tetik MD, Guillaume Boutillier MD, David Toubeau, Fanny Chaventre, Anaïs Vautier MD, Julie Gueudry MD, PhD, Marc Muraine MD, PhD","doi":"10.1016/j.ajoc.2025.102403","DOIUrl":"10.1016/j.ajoc.2025.102403","url":null,"abstract":"<div><h3>Purpose</h3><div>Pupilloplasty techniques are delicate, especially in phakic patients where the risk of touching the lens with the needle during the procedure is high. We report the case of a phakic patient in whom we used an allogeneic Kerato-lenticule Extraction (KLEx) lenticule temporarily to protect the lens during the procedure.</div></div><div><h3>Observation</h3><div>This is a 43-year-old male patient with a significant post-traumatic temporal iris defect. The patient complained of permanent discomfort in the form of monocular diplopia and photophobia. Surgery was performed under local anesthesia. The first step was to position a 6.5 mm-diameter, 109 μm-thick KLEx lenticule in front of the crystalline lens. The iris defect was then repaired with greater safety by positioning prolene knots using the Siepser technique. At the end of the procedure, the lenticule was removed from the anterior chamber. Post-operative follow-up confirmed the absence of lens damage, with no cataract at 6 months post-op.</div></div><div><h3>Conclusions and importance</h3><div>We report here a new technique in pupilloplasty by using a temporary KLEx lenticule as part of the iris repair. We found the procedure much less risky when the needles were passed anterior to the crystalline lens.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"39 ","pages":"Article 102403"},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case of severe bilateral chorioretinal coccidioidomycosis in an immunocompromised pediatric patient with Takayasu Arteritis 一个罕见的病例严重的双侧绒毛膜视网膜球虫菌病在免疫功能低下的儿童患者与高须动脉炎

American Journal of Ophthalmology Case Reports Pub Date : 2025-07-28 DOI: 10.1016/j.ajoc.2025.102407

Arthur Brant, Hashem Ghoraba, Brian Soetikno, Prithvi Mruthyunjaya, Quan Nguyen, Darius Moshfeghi, Charles Deboer, M. Elizabeth Hartnett

{"title":"A rare case of severe bilateral chorioretinal coccidioidomycosis in an immunocompromised pediatric patient with Takayasu Arteritis","authors":"Arthur Brant, Hashem Ghoraba, Brian Soetikno, Prithvi Mruthyunjaya, Quan Nguyen, Darius Moshfeghi, Charles Deboer, M. Elizabeth Hartnett","doi":"10.1016/j.ajoc.2025.102407","DOIUrl":"10.1016/j.ajoc.2025.102407","url":null,"abstract":"<div><h3>Purpose</h3><div>To report a case of severe bilateral coccidioidomycosis chorioretinitis in an immunosuppressed pediatric patient, demonstrating significant management challenges, therapeutic interventions, and a favorable outcome.</div></div><div><h3>Observations</h3><div>A 14-year-old female with a history of 1p36 microdeletion and Takayasu Arteritis (TA), managed with adalimumab and mycophenolate, presented with acute respiratory symptoms and bilateral vision impairment. She had severe bilateral diffuse chorioretinitis and an anterior chamber sample revealed coccidioidomycosis. Over the next few months, she underwent 14 serial intravitreal injections in each eye (1 amphotericin, 13 voriconazole), intravenous amphotericin B and fluconazole, and restarted on immunosuppressants for her TA. At 8 months following initial presentation, her vision remains 20/100 in the right eye and 20/125 in the left eye.</div></div><div><h3>Conclusions and importance</h3><div>This case illustrates a rare occurrence of coccidioidomycosis with bilateral chorioretinal involvement, necessitating aggressive and prolonged antifungal therapy. The successful salvage of both globes and vision in such a severe bilateral infection highlights the potential of intensive, multi-modality treatment strategies in similar cases. Further studies are warranted to understand the optimal management of chorioretinal coccidioidomycosis and the impact of systemic immunosuppression.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"39 ","pages":"Article 102407"},"PeriodicalIF":0.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144767046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toxic posterior segment syndrome caused by silicone oil tamponade resulting in postsurgical retinal vascular occlusion: a case report 硅油填塞致视网膜血管闭塞术后中毒性后段综合征1例

American Journal of Ophthalmology Case Reports Pub Date : 2025-07-28 DOI: 10.1016/j.ajoc.2025.102404

Miho Kumoi, Satoshi Matsuda, Mai Matsumoto, Chieko Tsujino, Yasumasa Otori

{"title":"Toxic posterior segment syndrome caused by silicone oil tamponade resulting in postsurgical retinal vascular occlusion: a case report","authors":"Miho Kumoi, Satoshi Matsuda, Mai Matsumoto, Chieko Tsujino, Yasumasa Otori","doi":"10.1016/j.ajoc.2025.102404","DOIUrl":"10.1016/j.ajoc.2025.102404","url":null,"abstract":"<div><h3>Purpose</h3><div>We aimed to report a rare case of postoperative retinal vessel occlusion caused by silicone oil.</div></div><div><h3>Observations</h3><div>A 71-year-old male patient presented with decreased visual acuity and was diagnosed with macular hole retinal detachment (MHRD). The patient underwent pars plana vitrectomy (PPV) and was administered a silicone oil injection. The day after surgery, although inflammation and hyperemia within the anterior chamber were mild, fundus examination revealed evidence of retinal blood vessel occlusion. The patient was assumed to have contracted bacterial endophthalmitis and underwent PPV again, wherein the silicone oil was removed followed by antibiotic administration and steroid eye drops initiation. The inflammation improved 2 weeks after surgery; the patient underwent a second operation for MHRD and was administered a silicone oil injection. However, the same vascular occlusion findings were observed the day after surgery. Vascular occlusion was thought to be due to sterile inflammation rather than bacterial endophthalmitis; the inflammatory findings subsided after silicone oil removal.</div></div><div><h3>Conclusions</h3><div>In cases of retinal vascular occlusion occurring early after silicone oil injection, if the anterior segment inflammation is mild, the possibility of toxic posterior segment syndrome must be considered.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"39 ","pages":"Article 102404"},"PeriodicalIF":0.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0