American Journal of Ophthalmology Case Reports最新文献_第10页

Development of posterior staphyloma in a child with retinitis pigmentosa and high myopia detected by Ultra-widefield Optical Coherence Tomography: A 4-year follow-up 超宽视场光学相干断层扫描检测色素性视网膜炎和高度近视儿童后葡萄肿的发展：4年随访

American Journal of Ophthalmology Case Reports Pub Date : 2025-03-05 DOI: 10.1016/j.ajoc.2025.102301

Changyu Chen, Kyoko Ohno-Matsui

引用次数: 0

Presumed Ocular tuberculosis masquerading as autoimmune retinopathy 假定的眼结核伪装成自身免疫性视网膜病变

American Journal of Ophthalmology Case Reports Pub Date : 2025-03-05 DOI: 10.1016/j.ajoc.2025.102296

Si-meng Hou , Qian Liu , Xiao-hui Zhang , Xiao-yan Peng , Hui-yang Zeng

引用次数: 0

Vogt-Koyanagi-Harada disease in a patient with retinitis pigmentosa in one eye and pigmented paravenous retinochoroidal atrophy in the other eye Vogt-Koyanagi-Harada病患者单眼色素性视网膜炎，另眼色素性静脉视网膜脉络膜萎缩

American Journal of Ophthalmology Case Reports Pub Date : 2025-03-05 DOI: 10.1016/j.ajoc.2025.102298

Junya Sato, Kouhei Hashizume, Yasuhiro Nishida, Shigenori Miyoshi, Mana Nagasawa, Daijiro Kurosaka

{"title":"Vogt-Koyanagi-Harada disease in a patient with retinitis pigmentosa in one eye and pigmented paravenous retinochoroidal atrophy in the other eye","authors":"Junya Sato, Kouhei Hashizume, Yasuhiro Nishida, Shigenori Miyoshi, Mana Nagasawa, Daijiro Kurosaka","doi":"10.1016/j.ajoc.2025.102298","DOIUrl":"10.1016/j.ajoc.2025.102298","url":null,"abstract":"<div><h3>Purpose</h3><div>To report a case of Vogt-Koyanagi-Harada (VKH) disease in a patient with retinitis pigmentosa (RP) in the right eye and pigmented paravenous retinochoroidal atrophy (PPRCA) in the left eye.</div></div><div><h3>Observations</h3><div>A 32-year-old woman with a history of RP visited our hospital with blurred vision in the left eye. She had a headache for four days before the onset of vision loss. Slit-lamp examination revealed bilateral inflammation of the anterior chamber and vitreous. Fundus examination revealed atrophy of the retinal pigment epithelium (RPE) and diffuse bone spicule pigmentation in the right eye, as well as retinochoroidal atrophy in the peripapillary region and extending along the retinal veins, accompanied by bone spicule pigmentation in the left eye. Optical coherence tomography (OCT) demonstrated serous retinal detachment (SRD) with hyperreflective material only in the left eye and increased choroidal thickness (CT) around the fovea in both eyes. Cerebrospinal fluid (CSF) analysis showed lymphocytic pleocytosis. The patient was diagnosed with incomplete VKH disease. After treatment with methylprednisolone, SRD in the left eye completely disappeared, and CT decreased bilaterally.</div></div><div><h3>Conclusions and Importance</h3><div>SRD, one of the major characteristic symptoms of VKH disease, may not be common in patients with both RP and VKH disease. VKH disease is associated with meningitis, vitiligo, and hearing loss, but signs other than meningitis are less frequent. However, in RP patients with uveitis, examination of the patient for these non-ocular signs may be needed to diagnose VKH disease.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"38 ","pages":"Article 102298"},"PeriodicalIF":0.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143593586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Basal cell carcinoma and squamous cell carcinoma of the conjunctiva in a single lesion 结膜基底细胞癌和鳞状细胞癌的单一病变

American Journal of Ophthalmology Case Reports Pub Date : 2025-03-05 DOI: 10.1016/j.ajoc.2025.102300

Melissa A. Trudrung, Cole Bacig, Brandon Vander Zee, Heather Potter

{"title":"Basal cell carcinoma and squamous cell carcinoma of the conjunctiva in a single lesion","authors":"Melissa A. Trudrung, Cole Bacig, Brandon Vander Zee, Heather Potter","doi":"10.1016/j.ajoc.2025.102300","DOIUrl":"10.1016/j.ajoc.2025.102300","url":null,"abstract":"<div><h3>Introduction</h3><div>Basal cell carcinoma (BCC) occurrences in the conjunctiva are exceptionally rare. These lesions become exceedingly rarer next to an adjacent area of squamous cell carcinoma. A collision tumor of both basal cell and squamous cell carcinoma is infrequently encountered in the literature.</div></div><div><h3>Case presentation</h3><div>An elderly male patient was evaluated for concern of ocular surface squamous neoplasia on his left conjunctiva. The lesion appeared as a tan-white elevated lesion with atypical vessels in papillary fronds. The patient underwent surgical excision of the lesion, and the tissue was sent to ocular pathology for histopathologic evaluation. The final diagnosis was basal cell carcinoma and squamous cell carcinoma. The two tumors of both basal cell carcinoma and squamous cell carcinoma were juxtaposed with an abrupt transition zone with no fluidity of differentiation. The lesion had typical features for BCC with positive stain for Bcl-2, P63, P53, CD10, and BerEP4. Additionally, the SCC region stained positive for EMA, P63, and P53.</div></div><div><h3>Conclusion</h3><div>We report a single lesion of the conjunctiva with features of both basal cell carcinoma and squamous cell carcinoma. This case report describes a unique case of two independent neoplasms of the conjunctiva. This further adds to the literature of collision tumors to characterize the lesion with appropriate immunohistochemical analysis.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"38 ","pages":"Article 102300"},"PeriodicalIF":0.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to “Neuro-ophthalmic complications following eighth cranial nerve microvascular decompression” [Am J Ophthalmol Case Rep (2025) eCollection 1–3 102258] “第八次颅神经微血管减压术后的眼神经并发症”的更正[美国眼科病例报告（2025）汇编1-3 102258]

American Journal of Ophthalmology Case Reports Pub Date : 2025-03-04 DOI: 10.1016/j.ajoc.2025.102295

Stanley M. Saju , Patrick J. Hunt , Pamela Davila-Siliezar , Noor Laylani , Andrew G. Lee

引用次数: 0

Myiasis of an exenterated orbital socket 眼窝切除后的蝇蛆病

American Journal of Ophthalmology Case Reports Pub Date : 2025-02-27 DOI: 10.1016/j.ajoc.2025.102293

Jie Cheng Song , Vivien Nguyen , Alexandra I. Manta

引用次数: 0

Third nerve palsy as first presenting symptom of Guillain-Barre Syndrome spectrum clinical variant 第三神经麻痹为格林-巴利综合征谱系临床变异的首发症状

American Journal of Ophthalmology Case Reports Pub Date : 2025-02-25 DOI: 10.1016/j.ajoc.2025.102291

Uma L. Balakrishnan , Nilesh K. Desai , Kimberly G. Yen

{"title":"Third nerve palsy as first presenting symptom of Guillain-Barre Syndrome spectrum clinical variant","authors":"Uma L. Balakrishnan , Nilesh K. Desai , Kimberly G. Yen","doi":"10.1016/j.ajoc.2025.102291","DOIUrl":"10.1016/j.ajoc.2025.102291","url":null,"abstract":"<div><h3>Purpose</h3><div>To report an unusual presentation of a Guillain-Barre Syndrome (GBS) spectrum clinical variant with an initial isolated, unilateral third nerve palsy prior to development of areflexia and lower extremity weakness.</div></div><div><h3>Observations</h3><div>A 16-month-old presented with a pupil-involving right third nerve palsy and normal lower extremity strength and reflexes. She was treated with a short oral steroid taper for presumed post-infectious cranial nerve (CN) palsy and had initial improvement. Soon after completing the taper, she developed an inability to sit, stand, or crawl with lower extremity areflexia. Magnetic resonance imaging of the spine showed diffusely thickened and enhancing cauda equina nerve roots and lumbar puncture showed isolated elevated protein, consistent with a diagnosis of a GBS spectrum disorder. She was treated with intravenous immunoglobulin and had complete resolution of ptosis as well as normal extraocular movements.</div></div><div><h3>Conclusions and importance</h3><div>Pediatric cases of acute third nerve palsy are most often traumatic, neoplastic, vascular, or demyelinating. These cases are less likely to have a post-viral etiology in contrast to the more commonly encountered acquired sixth nerve palsy. An isolated, unilateral third nerve palsy is a rare presentation of GBS and its clinical variant Miller Fisher Syndrome. This case demonstrates the importance of a high level of suspicion, particularly in the context of worsening systemic symptoms, to include these demyelinating disorders as a possible cause of unilateral CN palsy, as they can have a good prognosis if treated appropriately.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"38 ","pages":"Article 102291"},"PeriodicalIF":0.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Burkitt's lymphoma presenting as acute dacryocystitis in a 14-year-Old male with ataxia telangiectasia: A case report and review of the literature 伯基特淋巴瘤表现为急性泪囊炎的14岁男性共济失调毛细血管扩张：一个病例报告和文献复习

American Journal of Ophthalmology Case Reports Pub Date : 2025-02-24 DOI: 10.1016/j.ajoc.2025.102288

Samin Khannejad , Sajad Mansourian , Amirhossein Aghajani , Zohreh Nozarian , Seyed Mohsen Rafizadeh

{"title":"Burkitt's lymphoma presenting as acute dacryocystitis in a 14-year-Old male with ataxia telangiectasia: A case report and review of the literature","authors":"Samin Khannejad , Sajad Mansourian , Amirhossein Aghajani , Zohreh Nozarian , Seyed Mohsen Rafizadeh","doi":"10.1016/j.ajoc.2025.102288","DOIUrl":"10.1016/j.ajoc.2025.102288","url":null,"abstract":"<div><h3>Purpose</h3><div>This report describes an atypical presentation of a case of Burkitt lymphoma in a pediatric patient with ataxia telangiectasia.</div></div><div><h3>Main observations</h3><div>A 14-year-old boy with a history of AT was referred to our hospital with lower eyelid swelling and medial canthus abscess. On physical examination, movement of the left eye was limited in downgaze and adduction. Two mm proptosis was observed on the left side. Snellen's Visual acuity in the left eye was 8/20. The rest of the examination was normal. Magnetic resonance imaging (MRI) was performed and showed an infiltrative mass in the inferior of the left orbit, left ethmoidal sinus, and maxillary sinus. The patient subsequently underwent an incisional biopsy. The biopsy specimen was sent for histopathologic evaluation. Histopathology was significant for atypical monotonous cell infiltrations in the fibroconnective tissue and the presence of pleomorphic, irregularly shaped nuclei with multiple mitoses. Immunohistochemistry (IHC) findings were consistent with Burkitt's lymphoma, and the patient was referred to the oncology department for chemotherapy and appropriate treatment.</div></div><div><h3>Conclusion</h3><div>and Significance</div><div>Orbital and lacrimal duct involvement is a rare presentation of Burkitt lymphoma especially in the pediatric population. In the new-onset nasolacrimal duct obstruction (NLDO) in a child or teenager, the differential diagnosis should include malignancies, especially leukemia/lymphoma infiltrations.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"38 ","pages":"Article 102288"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143529208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outer retinal reflectivity and visual function loss after anatomically successful macula-off rhegmatogenous retinal detachment repair 解剖上成功的黄斑孔源性视网膜脱离修复后的外视网膜反射率和视觉功能丧失

American Journal of Ophthalmology Case Reports Pub Date : 2025-02-24 DOI: 10.1016/j.ajoc.2025.102294

Ajay Kolli , Jessica Wong , Stephanie Duret , Jay M. Stewart , Thomas B. Connor Jr. , Austin Roorda , Joseph Carroll , Jacque L. Duncan

{"title":"Outer retinal reflectivity and visual function loss after anatomically successful macula-off rhegmatogenous retinal detachment repair","authors":"Ajay Kolli , Jessica Wong , Stephanie Duret , Jay M. Stewart , Thomas B. Connor Jr. , Austin Roorda , Joseph Carroll , Jacque L. Duncan","doi":"10.1016/j.ajoc.2025.102294","DOIUrl":"10.1016/j.ajoc.2025.102294","url":null,"abstract":"<div><h3>Purpose</h3><div>Rhegmatogenous retinal detachment (RRD) can cause permanent photoreceptor damage with subsequent vision loss, even after prompt repair. Here we compared photoreceptor structure in retinal areas with varying levels of residual visual function loss following anatomically successful macula-off RRD repair.</div></div><div><h3>Observations</h3><div>Five eyes of four individuals (2 male, 2 female; ages 18–77 years) with successful macula-off RRD repair were included. Two were repaired via scleral buckle, one via vitrectomy, and two with both. Postoperative visual acuity measured 4–11 months after surgical repair ranged from 20/20 to 20/100. In each eye, areas of previously detached macula exhibited reduced or variable cone reflectivity on adaptive optics scanning light ophthalmoscopy (AOSLO) images. This was typically associated with reduced or variable inner segment/outer segment junction (IS/OS) band reflectivity on optical coherence tomography (OCT) images. Areas of the macula with reduced photoreceptor reflectivity also showed lower sensitivity on microperimetric testing.</div></div><div><h3>Conclusions</h3><div>Despite anatomically successful repair, RRD results in photoreceptor changes, including reduced reflectivity of cone profiles and the IS/OS band that were associated with reduced macular sensitivity. As ophthalmologic imaging progresses towards higher resolution modalities, AOSLO may be useful in monitoring outcomes after RRD repair. Low cone reflectivity, cataract, high axial length, and poor visual fixation may be barriers to quantification of cone structure in this patient population.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"38 ","pages":"Article 102294"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Allogeneic anterior lens capsule transplantation (ALCT) for the management of HSV neurotrophic keratitis 同种异体前晶状体囊移植治疗HSV神经营养性角膜炎

American Journal of Ophthalmology Case Reports Pub Date : 2025-02-23 DOI: 10.1016/j.ajoc.2025.102292

George D. Kymionis , Dionysios G. Vakalopoulos , Marina S. Chatzea, Konstantina A. Togka, Vasileios A. Tsagkogiannis, Petros C. Petrou

{"title":"Allogeneic anterior lens capsule transplantation (ALCT) for the management of HSV neurotrophic keratitis","authors":"George D. Kymionis , Dionysios G. Vakalopoulos , Marina S. Chatzea, Konstantina A. Togka, Vasileios A. Tsagkogiannis, Petros C. Petrou","doi":"10.1016/j.ajoc.2025.102292","DOIUrl":"10.1016/j.ajoc.2025.102292","url":null,"abstract":"<div><h3>Purpose</h3><div>To report a case of allogeneic anterior lens capsule transplantation (ALCT) for the management of HSV neurotrophic epithelial keratitis.</div></div><div><h3>Observations</h3><div>An 81-year-old man was referred to our department due to neurotrophic keratitis in the left eye that he had been suffering from over the past 3 months. He had recurrent episodes of HSV keratitis in the left eye over the past 3 years and despite multiple previous treatments, there was no improvement. At the time of presentation, corrected distance visual acuity (CDVA) was 20/200 in the right eye and no light perception (NLP) in the left eye. Slit-lamp examination revealed a corneal epithelial defect with underlying stromal thinning and concomitant scarring. An allogeneic anterior lens capsule (ALC) was placed over the epithelial defect to act as a biological dressing, anchored with a droplet of fibrin glue. A bandage contact lens (BCL) was placed over to prevent the slippage of the ALC. No intra or postoperative complications were observed. Two weeks later, the ALC was removed revealing complete epithelial healing, while two months later the epithelium remained completely healed with a significant reduction of corneal scarring.</div></div><div><h3>Conclusions and importance</h3><div>Anterior Lens Capsule transplantation (ALCT) seems to be a promising new treatment option for the management of corneal neurotrophic keratitis.</div></div>","PeriodicalId":7569,"journal":{"name":"American Journal of Ophthalmology Case Reports","volume":"38 ","pages":"Article 102292"},"PeriodicalIF":0.0,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143510276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0