Russian Chemical Bulletin最新文献

Polyimides based on unsymmetrical 3,4′-[4,4′-(diphenyldioxy)]diphthalic anhydride: synthesis and properties 基于不对称3,4 ' -[4,4 ' -（二苯二氧基）]二苯二酸酐的聚酰亚胺：合成及性能

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4734-z

D. A. Chistyakova, A. Yu. Tsegelskaya, M. S. Piskarev, K. V. Lisenkov, R. N. Shamsutdinova, T. S. Kurkin, V. L. Baklagin, I. G. Abramov, A. E. Soldatova, A. A. Kuznetsov

{"title":"Polyimides based on unsymmetrical 3,4′-[4,4′-(diphenyldioxy)]diphthalic anhydride: synthesis and properties","authors":"D. A. Chistyakova, A. Yu. Tsegelskaya, M. S. Piskarev, K. V. Lisenkov, R. N. Shamsutdinova, T. S. Kurkin, V. L. Baklagin, I. G. Abramov, A. E. Soldatova, A. A. Kuznetsov","doi":"10.1007/s11172-025-4734-z","DOIUrl":"10.1007/s11172-025-4734-z","url":null,"abstract":"<div><p>A series of new polyetherimides (PEIs) based on unsymmetrical 3,4′-(4,4′-(diphenyldioxy)diphthalic anhydride and a number of diamines were synthesized by single-stage high-temperature catalytic polycondensation in molten benzoic acid used as the so-called “active medium”. The chemical structure and phase morphology of the polycondensation products were studied by <sup>1</sup>H NMR and IR spectroscopies and by wide-angle X-ray scattering. The molecular weight characteristics were studied by viscometry and GPC methods. The synthesized PEIs are high-molecular-weight, film-forming, amorphous polymers that are soluble in organic solvents and possess good mechanical properties. The thermal properties of the synthesized PEIs were evaluated by DSC, TMA, and TGA methods. The polymers have high thermal and thermo-oxidative stability (> 500 °C), while their glass transition temperatures lie in the range of 220–300 °C depending on the diamine used in the synthesis. The rheological properties of melts were studied for a number of thermoplastic PEIs.</p></div>","PeriodicalId":756,"journal":{"name":"Russian Chemical Bulletin","volume":"74 8","pages":"2535 - 2544"},"PeriodicalIF":1.7,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145037081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Active site as the heart of carbohydrases 活性部位作为碳水化合物酶的心脏

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4710-7

A. S. Dotsenko, A. M. Rozhkova, I. N. Zorov, O. A. Sinitsyna, S. A. Kurzeev, A. P. Sinitsyn

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Fluorene attachment to graphene and MoS2 monolayers: impact on electronic and optical properties 石墨烯和二硫化钼单层上的芴附着：对电子和光学性质的影响

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4720-5

V. A. Demin, D. G. Kvashnin

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Nanosized polymer-enzyme films based on poly(ionic liquids): design and application 基于聚离子液体的纳米聚合物酶膜：设计与应用

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4728-x

L. V. Sigolaeva, N. S. Rudakov, I. N. Kurochkin, D. V. Pergushov

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Molecular approach to evaluate the integrity of the serum albumin adsorption layer on the surface of mixed iron oxide nanoparticles 用分子方法评价混合氧化铁纳米颗粒表面血清白蛋白吸附层的完整性

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4727-y

A. V. Bychkova, M. I. Abdullina, A. V. Toroptseva, M. G. Gorobets, D. S. Khachatryan, V. N. Osipov, D. S. Tungusov, M. S. Veresova, A. I. Shalupov, M. I. Biryukova, E. A. Kostanova

{"title":"Molecular approach to evaluate the integrity of the serum albumin adsorption layer on the surface of mixed iron oxide nanoparticles","authors":"A. V. Bychkova, M. I. Abdullina, A. V. Toroptseva, M. G. Gorobets, D. S. Khachatryan, V. N. Osipov, D. S. Tungusov, M. S. Veresova, A. I. Shalupov, M. I. Biryukova, E. A. Kostanova","doi":"10.1007/s11172-025-4727-y","DOIUrl":"10.1007/s11172-025-4727-y","url":null,"abstract":"<div><p>A new approach to evaluate the stability and integrity of a protein layer coating the surface of magnetic iron oxide nanoparticles (IONPs) in an aqueous medium was described using human serum albumin (HSA) as an example. The approach envisages investigation of the catalytic (peroxidase-like) activity of IONPs characterized by the generation rate of a colored product of <i>o</i>-phenylenediamine oxidation and examination of the capability of IONPs of binding to the plasma protein immunoglobulin G (IgG) to form submicron- and micron-sized aggregates. A correlation between the generation rate of hydroxyl radicals and the integrity of the HSA coating on the IONP surface (confirmed by experiments using IgG) was established for the first time. The approach developed belongs to the methods with a gentle impact on systems (non-damaging and low-damaging methods) for <i>in situ</i> and <i>ex situ</i> applications. The approach provides new possibilities for studying the physicochemical properties of hybrid nanosystems or submicron systems at various steps of their synthesis, as well as near physiological conditions, for example, in the blood plasma.</p></div>","PeriodicalId":756,"journal":{"name":"Russian Chemical Bulletin","volume":"74 8","pages":"2466 - 2474"},"PeriodicalIF":1.7,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145037080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Synthesis and spectral properties of new 1,4-benzodiazepin(benzoxazepin)one derivatives 新型1,4-苯并二氮平（苯并恶氮平）衍生物的合成及光谱性质

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4740-1

Yu. A. Kovygin, I. S. Zotova, M. V. Ser’ogin, D. V. Nikitenko, A. I. Slivkin, Kh. S. Shikhaliev

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New functions of cholinesterases in the development of Alzheimer’s disease as a target for neuroprotective drugs 作为神经保护药物靶点的胆碱酯酶在阿尔茨海默病发展中的新功能

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4715-2

G. F. Makhaeva, V. P. Fisenko, S. O. Bachurin

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Synthesis and biological activity of 5-sulfonamide-substituted 3-hydroxyoxindoles with 3-cyanomethyl and 3-carboxymethyl groups 含3-氰甲基和3-羧甲基的5-磺酰胺取代3-羟基氧吲哚的合成及生物活性研究

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4723-2

N. A. Lozinskaya, F. G. Bukhalovsky, D. V. Vinogradova, A. M. Efremov, O. V. Beznos, T. A. Pavlenko, L. V. Naumenko, A. S. Taran, A. M. Tcheban’ko, I. M. Veselov, A. A. Spasov, E. F. Shevtsova

{"title":"Synthesis and biological activity of 5-sulfonamide-substituted 3-hydroxyoxindoles with 3-cyanomethyl and 3-carboxymethyl groups","authors":"N. A. Lozinskaya, F. G. Bukhalovsky, D. V. Vinogradova, A. M. Efremov, O. V. Beznos, T. A. Pavlenko, L. V. Naumenko, A. S. Taran, A. M. Tcheban’ko, I. M. Veselov, A. A. Spasov, E. F. Shevtsova","doi":"10.1007/s11172-025-4723-2","DOIUrl":"10.1007/s11172-025-4723-2","url":null,"abstract":"<div><p>It was shown that sulfochlorination of isatins followed by reaction with amines and then with malonic acid derivatives is an efficient and highly efficient method for the synthesis of substituted oxindoles. The synthesis of a series of new 3-cyanomethyl- and 3-carboxymethyl-3-hydroxy-2-oxoindoline-5-sulfonamides was carried out, and their biological activity was evaluated <i>in vitro</i> for their effects on mitochondrial functions, lipid peroxidation, and the activity of recombinant human carbonic anhydrase II. It was found that the new compounds have weak antioxidant activity, do not affect mitochondrial membrane potential, and have low cytotoxicity towards human neuroblastoma SH-SY5Y cells. The effect of these compounds on intraocular pressure (IOP) was tested in experiments <i>in vivo</i>. A lead compound was identified that inhibited carbonic anhydrase II esterase activity with 99% efficiency at a concentration of 10 µmol L<sup>−1</sup>, but no correlation was observed between inhibition of carbonic anhydrase II and IOP reduction. At the same time, compounds effectively reducing IOP in rabbits and rats were found. Simultaneously, it was shown that the antiglaucomatous effect of the compounds varies depending on the animal species.</p></div>","PeriodicalId":756,"journal":{"name":"Russian Chemical Bulletin","volume":"74 8","pages":"2413 - 2426"},"PeriodicalIF":1.7,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145037073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Effect of the C-terminal sequence on the catalytic properties and thermal stability of bacterial formate dehydrogenase c端序列对细菌甲酸脱氢酶催化性能和热稳定性的影响

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4729-9

V. I. Tishkov, A. V. Zhadaev, D. L. Atroshenko, T. A. Chubar, A. A. Pometun, S. S. Savin

{"title":"Effect of the C-terminal sequence on the catalytic properties and thermal stability of bacterial formate dehydrogenase","authors":"V. I. Tishkov, A. V. Zhadaev, D. L. Atroshenko, T. A. Chubar, A. A. Pometun, S. S. Savin","doi":"10.1007/s11172-025-4729-9","DOIUrl":"10.1007/s11172-025-4729-9","url":null,"abstract":"<div><p>Nicotinamide adenine dinucleotide (NAD<sup>+</sup>)-dependent formate dehydrogenase (EC 1.2.1.2, FDH) from methylotrophic bacterium <i>Pseudomonas</i> sp.101 (PseFDH) is the most stable enzyme among natural orthologs and is widely used in the synthesis of chiral compounds with NAD(P)<sup>+</sup>-dependent oxidoreductases. PseFDH is a homodimer and belongs to the subfamily of classic bacterial formate dehydrogenases with a polypeptide chain length of 400 amino acids. In the apo form of PseFDH and its complex with formate (PDB_2NAC and PDB_2GUG, respectively), only 374 residues are visible in each subunit, and in the structure of the holo form (PseFDH—NAD<sup>+</sup>—azide ternary complex, PDB_2NAD), 391 and 383 residues are visible in two subunits. The amino acid sequencing of PseFDH isolated from the original strain <i>Pseudomonas</i> sp. 101, showed that the subunit in this enzyme consists of 393 residues. We prepared the full-length recombinant PseFDH consisting of 400 residues and truncated mutants consisting of 393, 383, and 374 residues (PseFDH_400, PseFDH_393, PseFDH_383, and PseFDH_374, respectively) and studied their properties. Our results and analysis of the structure of the holo form of FDH from <i>Moraxella</i> sp.C1 (PDB_2GSD) indicate that shortening of the C-terminus of PseFDH during isolation from the natural strain and the presence of 391, 383, and 374 residue subunits in the crystals are caused by proteolysis.</p></div>","PeriodicalId":756,"journal":{"name":"Russian Chemical Bulletin","volume":"74 8","pages":"2485 - 2493"},"PeriodicalIF":1.7,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145037076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Surface-enhanced Raman spectral features enrichment by selective hydrolysis of protein molecule peptide bonds 表面增强拉曼光谱特征通过选择性水解蛋白质分子肽键富集

IF 1.7 4区化学

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI: 10.1007/s11172-025-4719-y

A. D. Vasilyeva, I. A. Boginskaya, R. O. Aliev, L. V. Yurina, E. G. Evtushenko, M. I. Indeykina, K. N. Afanas’ev, M. V. Sedova, I. A. Ryzhikov, M. A. Rosenfeld, I. N. Kurochkin

引用次数: 0