Synthesis and spectral properties of new 1,4-benzodiazepin(benzoxazepin)one derivatives

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2025-09-12 DOI:10.1007/s11172-025-4740-1

Yu. A. Kovygin, I. S. Zotova, M. V. Ser’ogin, D. V. Nikitenko, A. I. Slivkin, Kh. S. Shikhaliev

引用次数: 0

Abstract

A convenient one-step synthesis of substituted 1,4-benzoxazepin-2-ones and 1,4-benzodiazepin-2-ones by recyclization of N-arylitaconimides with o-aminophenol and o-phenylenediamines. A detailed analysis of the spectral data of the synthesized compounds unambiguously confirmed the suggested structures. It was demonstrated that 1,4-benzoxazepin-2-ones are more conformationally flexible than 1,4-benzodiazepin-2-ones.

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新型1,4-苯并二氮平（苯并恶氮平）衍生物的合成及光谱性质

以邻氨基酚和邻苯二胺为原料，一步合成取代的1,4-苯并恶氮平-2-酮和1,4-苯并二氮平-2-酮。对合成化合物的光谱数据进行了详细的分析，毫不含糊地证实了所建议的结构。结果表明，1,4-苯并恶氮平-2-酮比1,4-苯并恶氮平-2-酮具有更强的构象柔韧性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.