Aktuelle Gerontologie最新文献_第8页

[Structure of supply--homes for the aged--as exemplified by a city (Nuremberg)]. [供给结构——老年人住房——以纽伦堡为例]。

Aktuelle Gerontologie Pub Date : 1982-09-01

B Mann

引用次数: 0

[Daily variations of plasma enzymes, plasma albumin and liver glycogen in 8- and 28-month-old rats]. [8月龄和28月龄大鼠血浆酶、血浆白蛋白和肝糖原的日变化]。

Aktuelle Gerontologie Pub Date : 1982-09-01

E Pav, H Bubna-Littitz

{"title":"[Daily variations of plasma enzymes, plasma albumin and liver glycogen in 8- and 28-month-old rats].","authors":"E Pav, H Bubna-Littitz","doi":"","DOIUrl":"","url":null,"abstract":"Male Sprague-Dawley rats aged 8 and 28 months (each group 36 animals) were used in our study of the variations during the day in plasma glucose, total protein and albumin, the activities of plasma ALD, LDH, GOT, GPT and the glycogen content of the liver. The variations in these enzymes shown in rats of different ages and at different times of the day were interpreted as expressions of different metabolic conditions of the liver because when changes in the membrane permeability occur or liver cells die changes in plasma enzyme activity can be expected to follow the same direction. Lowered GOT and GPT levels in the old rats and the same glycogen content of the liver as that of the young rats indicated a decreased glucose metabolism in the old animals. The LDH activity did not follow any time pattern. Daily variations in GPT and liver glycogen (the maximum of both parameters was between 4.00 and 8.00) were shown more distinctly in the old rats, whereas the daily variations in the plasma total protein and albumin showed minima between 8.00 and 12.00 in the young animals. The authors concluded that daily rhythms, essential for the function of the organism as a whole, are accentuated with ageing. On the other hand, rhythms of minor importance are desynchronized.","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 5","pages":"187-91"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17195841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Do the elderly receive adequate dental care? Determinants of the use of dental services by 60-to 90-year-old city dwellers. II]. 老年人是否得到足够的牙齿护理?60至90岁城市居民使用牙科服务的决定因素。二)。

Aktuelle Gerontologie Pub Date : 1982-09-01

V Garms-Homolová, U Hütter, C Leibing

引用次数: 0

[Determinants of successful aging in Switzerland]. [瑞士成功老龄化的决定因素]。

Aktuelle Gerontologie Pub Date : 1982-09-01

V G Blücher

{"title":"[Determinants of successful aging in Switzerland].","authors":"V G Blücher","doi":"","DOIUrl":"","url":null,"abstract":"The research, upon which this article is based is part of a program on \"Social Integration\" sponsored by the Swiss National Science Foundation. A sample of 4500 persons aged more than 59 years were interviewed in 1978. The theoretical approach was to identify the elements of successful aging under the conditions of swiss society, which are: the quality and degrees of independence and self determination of personality, continuity of the manner of living and adequate handling of the changing conditions of life in the third age including physical, mental, communicational and economic mutations. To reach this goal the survey measured the socio-economic conditions of the investigated population, their psycho-physical ability, how old people compensate deficits: the conditions essential for life, integration in leisure, private contacts, public opinions and political participation. The results show that a great majority is satisfied with the conditions of dwelling, occupation and economic conditions. But in all dimensions of life we also found minorities oppressed, threatened or deprived. Psycho-physical fitness proved to be in good state for a great majority and only a few percent were in a physical or mental condition which did not grant them independence and self-determination. This diagnosis was assisted by the results of two newly developed tests for meaning ability.","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 5","pages":"180-3"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17195080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Use of physical therapy and ergotherapy in the day hospital]. [在日间医院使用物理疗法和麦角疗法]。

Aktuelle Gerontologie Pub Date : 1982-09-01

S Weber, A Frei

引用次数: 0

[Iatrogenic disease in old age]. [老年医源性疾病]。

Aktuelle Gerontologie Pub Date : 1982-07-01

G Hitzenberger

引用次数: 0

[Drug treatment in the elderly: special aspects of diuretics (author's transl)]. 老年人的药物治疗:利尿剂的特殊方面(作者译)。

Aktuelle Gerontologie Pub Date : 1982-07-01

W Mühlberg, D Platt

{"title":"[Drug treatment in the elderly: special aspects of diuretics (author's transl)].","authors":"W Mühlberg, D Platt","doi":"","DOIUrl":"","url":null,"abstract":"Age-dependent changes in the pharmacokinetics of two diuretics, spironolactone and triamterene, were investigated in 20 geriatric patients with multiple diseases. Average plasma concentrations of canrenone (both determined by High-Performance-Liquid-Chromatography (HPLC) and a fluorimetric method) were significantly higher in geriatric patients compared with a younger control group of healthy volunteers (p less than 0,002). There was also a significant positive correlation between age (of the geriatric patients) and the area under the plasma concentration curve of canrenone. Plasma concentrations of canrenone (measured by HPLC after 120 hours) were closely correlated with number of red cells in the geriatric patients (p less than 0,01). Maximum plasma concentrations of triamterene and its pharmacologically active phase-II-metabolite were clearly higher in the geriatric patients when compared with a younger control group of healthy volunteers. Maximum plasma concentrations of the phase-II-metabolite were inversely correlated with diastolic blood pressure (p less than 0,01). Plasma levels of triamterene and its phase-II-metabolite in the older patients seem to be influenced not only renal perfusion pressure but also by uric acid levels.","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 4","pages":"134-8"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17192323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Stroke volume and cardiac output equivalents under orthostatic load in young and elderly volunteers (author's transl)]. [年轻和老年志愿者在直立负荷下的脑卒中量和心输出当量(作者译)]。

Aktuelle Gerontologie Pub Date : 1982-07-01

E Lang, R Kessel, R Woischke

{"title":"[Stroke volume and cardiac output equivalents under orthostatic load in young and elderly volunteers (author's transl)].","authors":"E Lang, R Kessel, R Woischke","doi":"","DOIUrl":"","url":null,"abstract":"With advancing age, orthostatic disturbances of regulation become clinically more relevant. They are observed in about 25% of persons older than 65 years, independent of their initial blood pressure. The stroke volume equivalents obtained by means of impedance cardiography enable the physician to differentiate between the behaviour during the early regulation phase and that during the phase of late regulation. The following conclusions can be drawn from the findings in 38 young volunteers (average age: 22 years) and 39 elderly volunteers (average age: 76 years): In elderly volunteers with normal late regulation, the stroke volume drops immediately by 16.1 ml and attains a maximum drop by 19.5 ml after ten minutes. Elderly volunteers with pathologic late regulation show a distinctly higher decrease in stroke volume by 38 to 42 ml below the initial level. With younger volunteers with normal late regulation, the stroke volume drops after positional change by 43 ml and attains an average minimum value of 55 ml after ten minutes. With the younger volunteers with pathologic late regulation, there is an average drop by 52.7 to max. 72.7 ml below the initial level. Assessment of the immediate regulation shows 2 different types of behaviour of orthostatic immediate regulation.","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 4","pages":"145-8"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17192326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The influence of persistent crowding on the spontaneous motor activity of the aging rat (author's transl)]. [持续拥挤对衰老大鼠自发性运动活动的影响[作者译]。

Aktuelle Gerontologie Pub Date : 1982-07-01

A Kment, G Hofecker, M Skalicky, H Niedermüller

{"title":"[The influence of persistent crowding on the spontaneous motor activity of the aging rat (author's transl)].","authors":"A Kment, G Hofecker, M Skalicky, H Niedermüller","doi":"","DOIUrl":"","url":null,"abstract":"In the course of a long-term cohort study of stress and aging, the spontaneous activity of 169 male Sprague-Dawley rats was measured at various ages from 9 to 30 months. 84 animals were submitted to crowding from the age of 5 months onwards by housing them in groups of 12 per Makrolon-IV cage. 85 rats, kept as usual in groups of 6 per makrolon-IV cage, served as a control. Spontaneous activity was assessed by an electronic instrument (Animex Activity Meter), which also enabled us to distinguish between total and large movements. During senescence, the spontaneous activity of the control animals decreased slightly by approximately 20% after the age of 18 months. In addition to the quantitative change, a progressive flattening of the activity rhythm was observed. The animals kept under crowded conditions did not reveal any age-related decrease in spontaneous activity. At an advanced age, this resulted in significantly higher activity values in the crowded group as compared with the controls. The differences appeared even earlier and seemed to be more pronounced in the number of large movements. However, the progressive disappearance of the endogenous rhythm was apparent in both the crowded and the control group. It can be concluded that at least two types of change in the central nervous system may be responsible for the aging-changes in spontaneous activity: one which disintegrates the \"time structure\" of the organism, and a second one which affects motivational centers. Crowded conditions seem to improve the latter, whereas they have no effect on the aging of the \"biological clock\".","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 4","pages":"128-33"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17193237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Iatrogenic diabetes mellitus (side effects and interactions of drugs during clinical diabetes mellitus (author's transl)]. [医源性糖尿病(临床糖尿病期间药物的副作用和相互作用[作者简介]]。

Aktuelle Gerontologie Pub Date : 1982-07-01

R P Königstein

{"title":"[Iatrogenic diabetes mellitus (side effects and interactions of drugs during clinical diabetes mellitus (author's transl)].","authors":"R P Königstein","doi":"","DOIUrl":"","url":null,"abstract":"After mentioning insulin deficiency diabetes in animals produced by drugs such as Alloxan, Diazoxide or Streptozotocin only drugs are discussed, which are used in elderly patients and may either provoke diabetes mellitus (or temporary hyperglycemia) or may change the clinical course of diabetes. In the first group endocrine products such as corticosteroids, estrogens, somatotrophic hormone, thyroid hormone, glucagon, somatostatin, catecholamines and hormones with anabolic effects are listed. The second group comprises saluretics, salicylates, amphetamines, pentamidine, nicotinic acid and its derivatives, beta-receptor blockers and finally laxatives. Hypopotassemia alone can also be the cause of hyperglycemia. Speaking of the sulfonylureapreparations, their interaction with alcohol, with phenylbutazone, with some sulfonamides and the effect of the sulfonylureas on peripheric insulin-receptors is discussed. In case of severe diabetic vascular disease the use of anticoagulants may lead to hemorrhages. If such an hemorrhage occurs in the eyes, it may lead to blindness. In diabetic nephropathy the use of phenacetine and its derivatives should be substituted by another medication. This review is not at all complete but should only show some of the problems in the treatment of elderly diabetic patients.","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 4","pages":"142-4"},"PeriodicalIF":0.0,"publicationDate":"1982-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17192325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0