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[Age dependency of platelet half life]. [血小板半衰期的年龄依赖性]。
Aktuelle Gerontologie Pub Date : 1982-11-01
H Sinzinger, E Jäger, C Leithner, R Höfer
{"title":"[Age dependency of platelet half life].","authors":"H Sinzinger,&nbsp;E Jäger,&nbsp;C Leithner,&nbsp;R Höfer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the last few years many reports have been published concerning shortened platelet half-life in different diseases such as atherosclerosis and hematological disorders. Up to the present moment, however, there is no information available concerning age and sex dependency in healthy people. Therefore, we evaluated platelet half-life in 106 patients, who had been examined because of a suspected atherosclerotic or hematological disorder having been excluded in the sequel. In all the patients we found negative bicycle ergometry and negative sonography of the carotid arteries and the legs. Platelets were labelled with 100 muCi of 111Indium-oxine-sulfate at 37 degrees C for 5 minutes. The mean labelling efficiency was 90%, the recovery about 70% after two hours. We found a statistically significant correlation (r = -0,5395; p less than 0,001 between age and platelet half-life. In male patients we observed a trend towards shortened platelet half-life, however, the differences were not significant.</p>","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 6","pages":"213-6"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17197437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The significance of age dependent organ changes for therapy]. [年龄依赖性器官变化对治疗的意义]。
Aktuelle Gerontologie Pub Date : 1982-11-01
D Platt
{"title":"[The significance of age dependent organ changes for therapy].","authors":"D Platt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Age dependent physiological alterations of the organs are superposed by pathological changes. The increase of the number of diseases with higher age results in difficulties in drug therapy. As the elderly patients take more medications than younger patients there is an increased incidence of adverse drug reactions in the elderly. Drug elimination occurs principally by two ways: excretion of unchanged drugs by the kidney and of metabolised drugs by the liver and/or kidney. Age dependent changes of these both organs as well as of the stomach and intestine are discussed.</p>","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 6","pages":"220-2"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17197439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
["I wanted to survive better with the help of university studies"]. [“我想在大学学习的帮助下更好地生存”]。
Aktuelle Gerontologie Pub Date : 1982-11-01
B Arnold, J Wortmann
{"title":"[\"I wanted to survive better with the help of university studies\"].","authors":"B Arnold,&nbsp;J Wortmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In West-Germany's Universities an interest in older students is emerging and the possibilities of integrating these students are discussed. This small study shows data about students born before 1937 who entered the University in the absence of special programs. The research interest was to learn something about the family and career background, the financial and social situation and the motivation of older students to continue their education at this University.</p>","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 6","pages":"223-7"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17197440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Geriatric training in Swiss medical departments]. [瑞士医疗部门的老年病学培训]。
Aktuelle Gerontologie Pub Date : 1982-11-01
J P Junod
{"title":"[Geriatric training in Swiss medical departments].","authors":"J P Junod","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Medical training in the geriatrics sector responds to a real and pressing necessity. The Swiss Gerontological Association has therefore set up a commission to investigate the basic features of a course of this nature and its implementation. The present report analyses the initial recordings.</p>","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 6","pages":"228-9"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17197441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Prostacyclin synthesis-stimulating plasma factor in different age groups]. [不同年龄组促前列环素合成血浆因子的研究]。
Aktuelle Gerontologie Pub Date : 1982-11-01
C Leithner, A Kefalides, C Hoche, H Sinzinger
{"title":"[Prostacyclin synthesis-stimulating plasma factor in different age groups].","authors":"C Leithner,&nbsp;A Kefalides,&nbsp;C Hoche,&nbsp;H Sinzinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The vascular synthesis of prostacyclin (PGI2), the most powerful endogenous inhibitor of platelet aggregation and vasodilator, plays a central role in prevention of vascular damages by uncontrolled platelet aggregation. PGI2 seems to be an important defense mechanism of vascular system against, among others, the development of atherosclerosis. The PGI2-production of blood vessels is stimulated and thereby decisively influenced by a plasma factor (PF). This PF participates in the pathogenesis of several diseases. This activity of PF is for instance increased in renal insufficiency, which explains partly the haemorrhagic diathesis occurring in this illness. On the other hand there seems to be a hereditary lack of PF in patients suffering from thrombotic-thrombocytopenic purpura or haemolytic-uraemic syndrome. The PF was estimated in 62 healthy subjects collected in 8 age groups by means of bioassays and RIA-determination of 6-oxo-PGF1 alpha, the stable PGI2-metabolite, in tissue cultures. No differences of PF in the different age groups could be demonstrated. These findings support the view, that the PF as an important regulator of vascular PGI2-synthesis is functioning absolutely normal in older age.</p>","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 6","pages":"217-9"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17197438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Retrospective follow-up study on 476 patients admitted for the first time to a nursing-home]. [对476例首次入住养老院患者的回顾性随访研究]。
Aktuelle Gerontologie Pub Date : 1982-11-01
H A Fabricius, M Martin
{"title":"[Retrospective follow-up study on 476 patients admitted for the first time to a nursing-home].","authors":"H A Fabricius,&nbsp;M Martin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During a seven-months' observation period the death-rate of 476 patients referred for the first time to a nursing home were checked up. In the first three months the rat of mortality was extremely high. With patients transferred from a hospital to a nursing-home the rate was much higher than among patients coming from their own home. The male mortality rate was higher than the female rate. The patients' age and the number of diseases diagnosed did not exercise any great influence on the mortality rate. Before admittance to the nursing-home, more males than females had been living in partnership.</p>","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 6","pages":"230-4"},"PeriodicalIF":0.0,"publicationDate":"1982-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17197442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pathological anatomy in senile dementia]. [老年痴呆的病理解剖]。
Aktuelle Gerontologie Pub Date : 1982-09-01
J Ulrich
{"title":"[Pathological anatomy in senile dementia].","authors":"J Ulrich","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 5","pages":"158-61"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17195073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Brain injuries and their sequelae in the aged. Problems of expert testimony on aged brain-injured persons]. 老年人脑损伤及其后遗症。老年脑损伤人员的专家鉴定问题[j]。
Aktuelle Gerontologie Pub Date : 1982-09-01
K Oesterreich
{"title":"[Brain injuries and their sequelae in the aged. Problems of expert testimony on aged brain-injured persons].","authors":"K Oesterreich","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 5","pages":"162-5"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17195074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Possible effects of working on the older co-worker]. [工作对年长同事的可能影响]。
Aktuelle Gerontologie Pub Date : 1982-09-01
E Abraham
{"title":"[Possible effects of working on the older co-worker].","authors":"E Abraham","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 5","pages":"184-6"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17195079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Senile Parkinsonism: its motor and psychological defects]. [老年帕金森病:运动与心理缺陷]。
Aktuelle Gerontologie Pub Date : 1982-09-01
W Birkmayer
{"title":"[Senile Parkinsonism: its motor and psychological defects].","authors":"W Birkmayer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>25% of patients with Parkinson's disease demonstrate the first symptoms with 70 years. The deficiency of Tyrosinhydroxylase is the trigger of the decreased level of Dopamin in the basal ganglia. The implications are the typical symptoms (tremor, rigor and akinesia) and the psychopathological decompensations as depression, delirs and bradyphrenie.</p>","PeriodicalId":75459,"journal":{"name":"Aktuelle Gerontologie","volume":"12 5","pages":"166-7"},"PeriodicalIF":0.0,"publicationDate":"1982-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17195075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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