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Acta vitaminologica et enzymologica最新文献

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Comparison of therapeutic usefulness of vitamin D3 analogs on osteoporosis caused by ovariectomy in rats. 维生素D3类似物对大鼠卵巢切除所致骨质疏松症的疗效比较。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
Y Izawa, K Sagara, T Kadota, T Makita
{"title":"Comparison of therapeutic usefulness of vitamin D3 analogs on osteoporosis caused by ovariectomy in rats.","authors":"Y Izawa,&nbsp;K Sagara,&nbsp;T Kadota,&nbsp;T Makita","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ovariectomy induced a remarkable reduction in the ash content of the femur and histologically a disappearance of the trabecular bone in tibial metaphysis accompanying the decrease of serum calcium level and urinary calcium excretion in young immature rats. Treatment with 1 alpha-hydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and 1,24R-dihydroxyvitamin D3 for 3 months from 7 to 9 months after the ovariectomy dose-dependently increased serum and urinary calcium, bone ash, and histologically partly improved a loss of trabeculae. The 24R,25-dihydroxyvitamin D3 doses, on the other hand, produced no therapeutic effect on the bone disorders in ovariectomized rats, except for the slight effect on the increasing activity of serum calcium.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"7 3-4","pages":"173-81"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14957200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[High resolution liquid chromatography (HPLC) analysis of the vitamin A and beta-carotene content of heat-treated precooked food]. [高分辨率液相色谱(HPLC)分析热处理预熟食品中维生素A和β -胡萝卜素的含量]。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
S Ciappellano, F Brighenti, M Porrini, G Testolin
{"title":"[High resolution liquid chromatography (HPLC) analysis of the vitamin A and beta-carotene content of heat-treated precooked food].","authors":"S Ciappellano,&nbsp;F Brighenti,&nbsp;M Porrini,&nbsp;G Testolin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Vitamin A and beta-carotene contents in 22 samples of precooked foods were determined before and after the use of various reheating techniques. The method used includes saponification by boiling with etOH and KOH, diethyl ether extraction in the presence of BHT as antioxidant, drying under controlled conditions and detection of the vitamins by HPLC. The results suggest good applicability of the procedure to food analysis and show how reheating processes can have a significant influence on the vitamin content of such foodstuffs.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"7 3-4","pages":"223-8"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15202438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The therapeutic effect of vitamins A and E in neurosensory hearing loss. 维生素A和E对神经性听力损失的治疗作用。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
G Romeo
{"title":"The therapeutic effect of vitamins A and E in neurosensory hearing loss.","authors":"G Romeo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After an anatomical and physiological outline of the organ of Corti, the pathology of the cochlea related to the sensorineural deafness is described. The role of Vitamin A on cochlear function and the effects of Vitamin E in man are then emphasized, on the base of some experimental results. Clinical and therapeutic efficacy of the combination of Vitamin A + E is shown by a number of papers, pointing out a 5-15 decibel improvement of the pure-tone threshold in patients with sensorineural hearing-loss particularly when the auditory troubles are due to presbyaccusis.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"7 Suppl ","pages":"85-92"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14958487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucocorticoid-induced bone disorders: nature and mechanisms of glucocorticoid-induced bone disorders in dogs. 糖皮质激素诱导的骨骼疾病:狗的糖皮质激素诱导的骨骼疾病的性质和机制。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
Y Izawa, T Makita, H Ichiki
{"title":"Glucocorticoid-induced bone disorders: nature and mechanisms of glucocorticoid-induced bone disorders in dogs.","authors":"Y Izawa,&nbsp;T Makita,&nbsp;H Ichiki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Treatment with 5.0 mg/kg of hydrocortisone twice a week for 12 months led to the significant decreased levels of serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D. A histomorphometric evaluation of iliac cortical and trabecular bones was carried out using tetracycline double labelling method and tetrachrome staining. The excessive hydrocortisone treatment produced poor or no fluorescent labelling in the iliac cortex, indicating the absence of any newly established bone. Our present data demonstrate that excessive glucocorticoid may induce bone disorder in dogs by indirectly causing the decrease of serum 1,25-dihydroxyvitamin D3 levels or by directly inhibiting mineral apposition of bone.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"7 1-2","pages":"77-84"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14955784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biochemical and clinical study of calcium pantetheine-S-sulfonate. 泛茶碱-s -磺酸钙的生化及临床研究。
Acta vitaminologica et enzymologica Pub Date : 1985-01-01
R Hayakawa, K Matsunaga, C Ukei, K Ohiwa
{"title":"Biochemical and clinical study of calcium pantetheine-S-sulfonate.","authors":"R Hayakawa,&nbsp;K Matsunaga,&nbsp;C Ukei,&nbsp;K Ohiwa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Calcium pantetheine-S-sulfonate (PaSSO3Ca) is one of the pantothenic acid derivatives. We examined PaSSO3Ca inhibition capacity of tyrosinase activity in vitro. For the safety evaluation when it will be applied to the human skin, we tested PaSSO3Ca creams to the fifty one patients with skin diseases by 48 hours closed patch test method. And clinical evaluation of PaSSO3Ca creams were performed in fifty patients with chloasma by half side method. Results were as follow: 1, PaSSO3Ca was proved to inhibit the tyrosinase activity in vitro. 2, PaSSO3Ca cream was shown to be safe to human skin. 3, 10% PaSSO3Ca cream lightened the skin hyperpigmentation.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"7 1-2","pages":"109-14"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15014943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urinary excretion of xanthurenic acid and zinc in diabetes: 1) Separation of xanthurenic acid-Zn2+ complex by ion-exchange chromatography. 糖尿病患者尿中黄嘌呤酸和锌的排泄:1)离子交换色谱法分离黄嘌呤酸- zn2 +络合物。
Acta vitaminologica et enzymologica Pub Date : 1984-12-31 DOI: 10.1515/9783111641546-048
S. Ikeda, Y. Kotake
{"title":"Urinary excretion of xanthurenic acid and zinc in diabetes: 1) Separation of xanthurenic acid-Zn2+ complex by ion-exchange chromatography.","authors":"S. Ikeda, Y. Kotake","doi":"10.1515/9783111641546-048","DOIUrl":"https://doi.org/10.1515/9783111641546-048","url":null,"abstract":"In view of the relevance of urinary xanthurenic acid (XA) and zinc in diabetes, a chromatographic procedure has been devised which allows separation of XA from its complex with Zn2+. The procedure involves chromatography on DEAE-Sepharose CL-6B at pH 7.2 with a stepwise Tris-HCl concentration gradient. The ultraviolet absorption difference spectra due to formation of the XA-Zn2+ complex allowed the estimate of the binding molar ratio in the XA-Zn2+ complex. This corresponds to a 1:1 as estimated on the basis of the Hill plot of the experimental data.","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"23 1","pages":"23-8"},"PeriodicalIF":0.0,"publicationDate":"1984-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/9783111641546-048","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67053348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Ascorbic acid in thyroidectomized rats. II) Ascorbic acid status of the storage tissues and hepatic biosynthesis of glucuronic acid. 去甲状腺大鼠抗坏血酸。II)抗坏血酸的储存组织状态和葡萄糖醛酸的肝脏生物合成。
Acta vitaminologica et enzymologica Pub Date : 1984-01-01
N Nath, M Nath, M G Muddeshwar
{"title":"Ascorbic acid in thyroidectomized rats. II) Ascorbic acid status of the storage tissues and hepatic biosynthesis of glucuronic acid.","authors":"N Nath,&nbsp;M Nath,&nbsp;M G Muddeshwar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Depletion of ascorbic acid from adrenals, brain and epididymis along with loss in weight were noticed in the state of thyroidectomy. This decrease appears to be due to an effect of thyroidectomy on the membrane integrity since the membrane bound sialic acid was found to be significantly lowered in these tissues as a consequence of the elevated activity of sialidase. Thyroidectomy was also found to cause an adverse effect on the activities of hepatic UDP-glucuronyl transferase and beta-glucuronidase with no alteration in UDP-glucose dehydrogenase.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"6 2","pages":"91-5"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17598399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal absorption of 5-methyltetrahydrofolate in experimental uremia. 5-甲基四氢叶酸在实验性尿毒症中的肠道吸收。
Acta vitaminologica et enzymologica Pub Date : 1984-01-01
H M Said, N D Vaziri, R K Kariger, D Hollander
{"title":"Intestinal absorption of 5-methyltetrahydrofolate in experimental uremia.","authors":"H M Said,&nbsp;N D Vaziri,&nbsp;R K Kariger,&nbsp;D Hollander","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Folate deficiency and megaloblastic anemia occur in chronic renal failure. However, the possible role of intestinal malabsorption as a cause of the reported deficiency has not been investigated. Therefore, we examined the intestinal absorption of 5-methyltetrahydrofolate in rats made uremic by subtotal nephrectomy using in vivo perfusion technique and in vitro everted sac technique. The results were compared with those obtained in a group of sham-operated rats with normal renal function. The amount of 5-methyltetrahydrofolate absorbed in vivo was significantly lower in the uremic animals as compared to the control group. In contrast, no significant difference was found in the absorption of 5-methyltetrahydrofolate in vitro in the two groups. To mimic the uremic environment, the in vitro studies were repeated using jejunal sacs from normal animals filled with either buffer solution, or sera from uremic patients before and after dialysis. Their results showed a marked suppression of 5-methyltetrahydrofolate absorption with predialysis sera and a significant improvement with post dialysis sera. We conclude that intestinal absorption of 5-methyltetrahydrofolate is impaired in uremia. The results of the in vitro experiments suggest that the observed transport defect is due to some influence of uremic environment rather than to an acquired intrinsic defect of enterocytes in uremia.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"6 4","pages":"339-46"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17590200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Possibility of diacetyl and related compounds as the 4-carbon compound necessary for the formation of riboflavin in Ashbya gossypii. 棉蚜核黄素形成所需的4碳化合物为二乙酰基及其相关化合物的可能性。
Acta vitaminologica et enzymologica Pub Date : 1984-01-01
K Nakajima, H Mitsuda
{"title":"Possibility of diacetyl and related compounds as the 4-carbon compound necessary for the formation of riboflavin in Ashbya gossypii.","authors":"K Nakajima,&nbsp;H Mitsuda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of various compounds (0.5%) involved in the butanediol and the glycolytic pathways on riboflavin formation in whole cells of Ashbya gossypii at rest were examined. The addition of acetate, glycerol and diacetyl inhibited riboflavin formation, while the addition of acetoin had no effect on it, and the addition of ethanol, 2,3-butanediol, pyruvic acid and glucose accelerated it. The relation of diacetyl and acetoin to riboflavin formation during resting cell incubation in the presence of 0.5% ethanol and various concentrations of 2,3-butanediol was examined. The results quantitatively revealed a precursor-product relation between riboflavin formation and the formation of diacetyl and acetoin. The results obtained provide evidence that a high flavinogenic agent, ethanol, was converted to acetaldehyde, pyruvic acid, acetoin and diacetyl in this order, that a week flavinogenic agent, 2,3-butanediol, was transferred to diacetyl through acetoin, and that the diacetyl produced can be utilized as the 4-carbon compound for riboflavin formation in the flavinogenic mold, Ashbya gossypii. It remains obscure whether diacetyl is enzymatically involved in riboflavin formation.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"6 4","pages":"271-82"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17590333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urinary excretion of xanthurenic acid and zinc in diabetes: 1) Separation of xanthurenic acid-Zn2+ complex by ion-exchange chromatography. 糖尿病患者尿中黄嘌呤酸和锌的排泄:1)离子交换色谱法分离黄嘌呤酸- zn2 +络合物。
Acta vitaminologica et enzymologica Pub Date : 1984-01-01
S Ikeda, Y Kotake
{"title":"Urinary excretion of xanthurenic acid and zinc in diabetes: 1) Separation of xanthurenic acid-Zn2+ complex by ion-exchange chromatography.","authors":"S Ikeda,&nbsp;Y Kotake","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In view of the relevance of urinary xanthurenic acid (XA) and zinc in diabetes, a chromatographic procedure has been devised which allows separation of XA from its complex with Zn2+. The procedure involves chromatography on DEAE-Sepharose CL-6B at pH 7.2 with a stepwise Tris-HCl concentration gradient. The ultraviolet absorption difference spectra due to formation of the XA-Zn2+ complex allowed the estimate of the binding molar ratio in the XA-Zn2+ complex. This corresponds to a 1:1 as estimated on the basis of the Hill plot of the experimental data.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":"6 1","pages":"23-8"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17524485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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