Acta vitaminologica et enzymologica最新文献_第10页

Pyridoxine for the suppression of lactation--a clinical trial on 1592 cases. 吡哆醇抑制泌乳——1592例临床试验

Acta vitaminologica et enzymologica Pub Date : 1983-08-01 DOI: 10.1097/00004714-198308000-00027

D. Scaglione, A. Vecchione

引用次数: 3

[Clinical study of a prepared reducing diet: adequacy of the vitamin-mineral contribution in comparison to the nutritional and immunity status]. [一种预备减量饮食的临床研究:与营养和免疫状况相比，维生素矿物质的贡献是否充足]。

Acta vitaminologica et enzymologica Pub Date : 1983-01-01

E Agradi, S Toma, G Vidali, E R Rossi, A Giacchero, N Ferrari, M Ferro

引用次数: 0

Effect of vitamin A deficiency on the level of glutathione and glutathione S-transferase activity in rat colon and liver. 维生素A缺乏对大鼠结肠和肝脏谷胱甘肽水平和谷胱甘肽s -转移酶活性的影响。

Acta vitaminologica et enzymologica Pub Date : 1983-01-01

M P Gupta, S C Dogra, K L Khanduja, R R Sharma

引用次数: 0

[Calcium-phosphorus changes in chronic anticonvulsant therapy: effects of the administration of 25-hydroxyvitamin D3 on secondary hyperparathyroidism]. [慢性抗惊厥治疗中的钙磷变化:25-羟基维生素D3对继发性甲状旁腺功能亢进的影响]。

Acta vitaminologica et enzymologica Pub Date : 1983-01-01

G Bianchini, S Mazzaferro, U Mancini, A R Bianchi, G Donato, C Massimetti, M R Faedda, G Sideri, G Coen

{"title":"[Calcium-phosphorus changes in chronic anticonvulsant therapy: effects of the administration of 25-hydroxyvitamin D3 on secondary hyperparathyroidism].","authors":"G Bianchini, S Mazzaferro, U Mancini, A R Bianchi, G Donato, C Massimetti, M R Faedda, G Sideri, G Coen","doi":"","DOIUrl":"","url":null,"abstract":"The present study represents a contribution to the knowledge of secondary hyperparathyroidism (SHP) in patients treated with anticonvulsant drugs (AC). In these subjects alterations of the calcium: phosphorus metabolism as rickets and osteomalacia are frequent; however literature data on SHP are scarce. Our research carried out on 29 adult patients under treatment with one or more AC for periods ranging from 9 months to 12 years confirmed that 25-OHD levels in the serum are low, especially in patients treated for longer times. The iPTH levels in the serum are increased with respect to normal controls, while blood calcium and phosphate levels are normal as are urine calcium and phosphate. The 25-OHD levels in serum present the same seasonal variations as the normal controls. The administration of 25-OHD3 (20 micrograms/day for 3 months) to 12 of these patients who had the lowest 25-OHD spring levels rendered the 25-OHD levels attain normal values. Cyclic AMP was normalized; serum and urine calcium and phosphorus and urinary hydroxyproline were not modified significantly. On the basis of the present data it is recommended that chronic AC treatment should be accompanied by long term administration of 25-OHD3 for prophylaxis and/or for treatment of SHP.","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17385188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of dietary coconut oil and casein and megadoses of vitamin A or C on tissue lipid peroxidation and hemolysis in vitamin E deficiency. 膳食中添加椰子油和酪蛋白以及大剂量维生素A或C对维生素E缺乏患者组织脂质过氧化和溶血的影响。

Acta vitaminologica et enzymologica Pub Date : 1983-01-01

S Krishnamurthy, T George, N Jayanthi Bai

{"title":"Effect of dietary coconut oil and casein and megadoses of vitamin A or C on tissue lipid peroxidation and hemolysis in vitamin E deficiency.","authors":"S Krishnamurthy, T George, N Jayanthi Bai","doi":"","DOIUrl":"","url":null,"abstract":"Male rats fed on pellet diet to an average weight of 105 g were placed on a vitamin E deficient diet containing 20% coconut oil for a period of 12 weeks at two dietary protein levels, 20% and 10% casein. Rats on 20% casein diet showed a definite weight loss but not so at the 10% casein level. A marked increase in the liver in vitro lipid peroxidation was observed at both protein levels. Feeding of retinyl palmitate at 100,000 IU/100 g body weight for 4 consecutive days inhibited the liver, brain and kidney in vitro peroxidation; megadoses of ascorbic acid produced less inhibition of the liver peroxidation, but the same degree of inhibition for brain and kidney peroxidation as in vitamin A loaded rats. Both dietary palmitate or ascorbic acid. Acetylcholine esterase and ATPase, two of the membrane enzymes of erythrocytes, were depressed in all the groups. The glutathione content of erythrocytes was increased in rats given ascorbic acid. In all the groups the higher dietary protein levels produced greater loss of body and tissue weights. It is concluded vitamin E deficient diet supplemented with dietary coconut oil (saturated fat) induces increased in vitro lipid peroxidation and oxidative lysis of erythrocytes and that megadoses of vitamin A or C suppress the in vitro lipid peroxidation but enhance the lysis.","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17704642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Determination of glutathione reductase activity in erythrocytes and whole blood as an indicator of riboflavin nutrition]. [测定红细胞和全血谷胱甘肽还原酶活性作为核黄素营养指标]。

Acta vitaminologica et enzymologica Pub Date : 1983-01-01

G Maiani, S Mobarhan, A Nicastro, F Virgili, C Scaccini, A Ferro-Luzzi

引用次数: 0

Lack of direct association between serum transferrin and serum biochemical indicators of vitamin A nutriture. 血清转铁蛋白与维生素A营养的血清生化指标之间缺乏直接联系。

Acta vitaminologica et enzymologica Pub Date : 1983-01-01

L A Mejia, G Arroyave

引用次数: 0

Ascorbic acid: a scavenger of superoxide radical. 抗坏血酸:一种超氧自由基的清除剂。

Acta vitaminologica et enzymologica Pub Date : 1983-01-01

S Som, C Raha, I B Chatterjee

引用次数: 0

Antivitamin B6 activity of L-penicillamine in Escherichia coli. l -青霉胺在大肠杆菌中的抗维生素B6活性。

Acta vitaminologica et enzymologica Pub Date : 1983-01-01

R Yamada

{"title":"Antivitamin B6 activity of L-penicillamine in Escherichia coli.","authors":"R Yamada","doi":"","DOIUrl":"","url":null,"abstract":"Escherichia coli wild strain K12 and the vitamin B6 requiring mutant strain KG980 were compared with respect to the growth inhibition by L-penicillamine and the reversal of inhibition with pyridoxine. The growth of KG980 was much more severely inhibited than that of K12 by relatively low concentrations of L-penicillamine, when KG980 was grown with a usually sufficient concentration of pyridoxine. The following findings indicated that this was because L-penicillamine caused vitamin B6 deficiency in KG980; (a) addition of excess pyridoxine significantly reversed the inhibition, (b) comparison of the growth with various concentrations of pyridoxine showed that the vitamin requirement became higher upon addition of L-penicillamine. Examination of cellular vitamin B6 compounds showed that pyridoxal 5'-phosphate was markedly decreased when L-penicillamine was present, in agreement with the probable reaction of the inhibitor with the coenzyme. On the other hand, the growth inhibition of K12 appeared independent of vitamin B6 deficiency, and the cellular pyridoxal 5,-phosphate was found not to be markedly reduced by the presence of L-penicillamine, while the total of vitamin B6 compounds, probably including the product formed by the coenzyme and the inhibitor, increased clearly. The results, therefore, suggest that the wild strain of E. coli can avoid the deficiency of vitamin B6 by enhancing its biosynthesis, although L-penicillamine acts as an antivitamin B6.","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17407620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Studies on the mechanism of retinoid-induced adhesion of spontaneously transformed mouse fibroblasts. 类维甲酸诱导小鼠自发转化成纤维细胞粘附机制的研究。

Acta vitaminologica et enzymologica Pub Date : 1983-01-01

S Adamo, W Sasak, L D Dion, L M De Luca

{"title":"Studies on the mechanism of retinoid-induced adhesion of spontaneously transformed mouse fibroblasts.","authors":"S Adamo, W Sasak, L D Dion, L M De Luca","doi":"","DOIUrl":"","url":null,"abstract":"Transformed cells (Balb/c, 3T12-3), induced to increase their adhesion to the substrate by treatment with retinoic acid, display higher incorporation of (2-(3)H)-mannose into both lipids and glycoproteins than untreated controls. Stimulation of (2-(3)H)-mannose incorporation into manno-lipids is evident 8 hr after exposing the cells to retinoic acid, and stimulation of tritiated mannose incorporation into glycoproteins occurs slightly later. SDS-PAGE of (2-(3)H)-mannose labelled glycoproteins indicates that both retinoic acid and retinol treatments stimulate the incorporation of the radiolabelled sugar into a glycoprotein with subunit MW 180,000 (Gp 180) and, to a lesser extent, into other glycoproteins. 3H-leucine incorporation into a protein banding at the same position as the 3H-mannose labelled Gp 180 does not appear to be affected by retinoid treatment. A retinoic acid induced increase in the amount of Gp 180 can also be shown by lactoperoxidase catalyzed radioiodination of cultured 3T12 cells, and controlled trypsin digestion experiments indicate that Gp 180 is a component of the cell surface. On the contrary, the increased cell adhesion to the substrate induced by retinoic acid is not accompanied, in this system, by an increase in the amount of fibronectin, as judged by iodination of the cell surface components followed by SDS-PAGE.","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17895949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0