Acta vitaminologica et enzymologica最新文献_第4页

[Facilitation of the onset of tetanic responses induced by 4-methylesculetol in amphibian isolated neuromuscular preparations]. [在两栖动物离体神经肌肉制剂中，4-甲基己甲醇诱导的破伤风反应的促进作用]。

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

R Aragno, V Bettini, L De Bartolomeis, P Fabro, P Ton, L Munari

{"title":"[Facilitation of the onset of tetanic responses induced by 4-methylesculetol in amphibian isolated neuromuscular preparations].","authors":"R Aragno, V Bettini, L De Bartolomeis, P Fabro, P Ton, L Munari","doi":"","DOIUrl":"","url":null,"abstract":"Previous observations have shown that the 4-Methylesculetin (4ME) and the calcium provoke an increased response when the motor somatic and autonomic nerve-endings are stimolated. In the present research, we have studied the influence of the bioflavonoid and of an increased medium [Ca++] on the tetanic responses obtained from the isolated frog \"sciatic nerve-gastrocnemius muscle\" preparation. The 4ME has always facilitated the beginning of a complete tetanic response and has also frequently increased the developed mechanical tension. These effects appeared more evident when the bioflavonoid was employed together with the ascorbic acid. Moreover, an increased medium [Ca++] has induced similar effects. The nifedipine and the flunarizine, well-known Ca++ -antagonists, have constantly reduced or even abolished the facilitating effect induced by the bioflavonoid. On the basis of these results, we could hypothize that these observed facilitating effects are dependent on both an increased Ach-release and an increased muscle mechanical efficiency. Our previous results and also some literature data suggest that these effects could be due to an increased Ca++-passage through the cell membrane of the motor nervendings and of the muscle fibres too.","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14136983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The biochemical and physiological role of vitamins A and E and their interactions. 维生素A和E的生化和生理作用及其相互作用。

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

A Hanck

引用次数: 0

Effect of beta-carotene on mutagenic activity of some antineoplastics. β -胡萝卜素对某些抗肿瘤药物致突变活性的影响。

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

A Belisario, N Panza, G Pacilio

引用次数: 0

Comparative study of mechanical responses of hepatic arteries strips to adrenalin in presence of pyridoxine and pyridoxal-5'-phosphate. 吡哆醇和吡哆醇-5′-磷酸存在下肝动脉条带对肾上腺素力学反应的比较研究。

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

V Bettini, R Martino, L Munari, F Mayellaro, P Ton

引用次数: 0

Function of vitamin A in the respiratory tract. 维生素A在呼吸道中的作用。

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

F Chytil

引用次数: 0

Studies on the 4-carbon compound needed for the formation of the O-xylene ring of riboflavin. 核黄素o -二甲苯环形成所需的4碳化合物的研究。

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

K Nakajima

{"title":"Studies on the 4-carbon compound needed for the formation of the O-xylene ring of riboflavin.","authors":"K Nakajima","doi":"","DOIUrl":"","url":null,"abstract":"The 4-carbon compound necessary for the formation of the o-xylene ring of riboflavin, was examined using labeled glucose and diacetyl in resting cells of Eremothecium ashbyii. The specific activity-time curves of riboflavin and lumichrome in the tracer experiments with [U-14C] glucose indicated that the specific activity of riboflavin during the incubation is much higher than that of its photolytic product, lumichrome. It is far above the level expected if the ribityl moiety of an intermediate, 4-ribitylamino-5-amino-2,6-dihydroxy-pyrimidine (RAADP), was to be utilized as the source of the 4-carbon unit on the o-xylene ring of riboflavin. It was further demonstrated that the specific activities of diacetyl and lumichrome at 10.5 h of the incubation and those of crystalline riboflavin and lumichrome at the later stage (20 h) of the incubation were identical respectively. Radioactive diacetyl furthermore proved to be likewise incorporated with a two fold dilution into riboflavin and lumichrome at 17 h of the incubation. The results reveal that it is not the ribityl fragment of RAADP bu the diacetyl that is the 4-carbon unit for the formation of the pyrazine ring of 6,7-dimethyl-8-ribityllumazine, that is, the o-xylene ring of riboflavin in the mold of Eremothecium ashbyii, although we still do not know whether the diketone requiring reaction is enzymatic or non-enzymatic.","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15153204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamin A: a key nutrient for the maintenance of epithelial differentiation. 维生素A:维持上皮细胞分化的关键营养素。

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

L M De Luca, D Roop, F L Huang

{"title":"Vitamin A: a key nutrient for the maintenance of epithelial differentiation.","authors":"L M De Luca, D Roop, F L Huang","doi":"","DOIUrl":"","url":null,"abstract":"Vitamin A deficiency or benzo(a)pyrene instillation into tracheas of Syrian golden hamsters causes squamous metaplasia of tracheobronchial epithelium, normally a mucous secretory tissue. In the present studies, we have employed a tracheal organ culture system and have reproduced the in vivo phenomenon of squamous metaplasia during culturing under vitamin A free conditions as well as after carcinogen treatment. The squamous metaplasia induced by vitamin A deficiency, both in vivo and in vitro, was accompanied by an overall increase in keratin synthesis. Vitamin A deficient tracheas were shown to contain keratins of 50, 48, 46.5 Kd detected with the antibody AE1, and 58, 56 and 52 Kd detected with AE3. These proteins were either absent or present in much less quantity in control tracheas. In deficient tracheas 60 kd keratin was found to be located specifically in squamous suprabasal cells, and 55 and 50 Kd keratin proteins were found in a greatly expanded basal cell compartment. Following carcinogen exposure, the appearance of 60 kd keratin and the enhanced expression of 50 and 55 Kd keratins preceded the squamoid metaplastic response as detected morphologically. Both the keratin changes and the morphological changes were prevented by retinoid treatment.","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13579139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of thiamine diphosphate-binding proteins from rat liver supernatant. 大鼠肝脏上清中硫胺素二磷酸结合蛋白的鉴定。

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

A I Voskoboyev, I P Chernikevich

引用次数: 0

1-Alpha-OH-cholecalciferol (1-alpha-OH-D3) and optimal calcium intake in calcium deficiency osteoporosis mediated by parathyroid activity morphologic and biochemical changes in adult male rats. 1- α - oh -胆钙化醇(1- α - oh - d3)和最佳钙摄入量在成年雄性大鼠甲状旁腺活性、形态学和生化变化介导的缺乏性骨质疏松症中的作用

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

T S Lindholm, O S Nilsson, T C Lindholm

引用次数: 0

Maternal plasma proteins, magnesium, zinc and copper concentration at term associated with birth size in Kuwait. 科威特孕妇足月血浆蛋白、镁、锌和铜浓度与出生尺寸有关。

Acta vitaminologica et enzymologica Pub Date : 1985-01-01

M S Mameesh, H Hathout, M A Safar, A Mahfouz, J M Al-Hassan

引用次数: 0