Acta pathologica japonica最新文献_第9页

An unusual heterotopia of pyloric glands of the stomach with inverted downgrowth. 胃幽门腺不寻常的异位，呈倒置向下生长。

Acta pathologica japonica Pub Date : 1993-04-01 DOI: 10.1111/j.1440-1827.1993.tb01131.x

Y Kamata, H Kurotaki, T Onodera, N Nishida

引用次数: 19

Hypoxic effects on glutamate uptake in cultured glial cells. 缺氧对培养神经胶质细胞谷氨酸摄取的影响。

Acta pathologica japonica Pub Date : 1993-04-01 DOI: 10.1111/j.1440-1827.1993.tb01126.x

M Ohashi, S Amano, F Hazama, J Handa

{"title":"Hypoxic effects on glutamate uptake in cultured glial cells.","authors":"M Ohashi, S Amano, F Hazama, J Handa","doi":"10.1111/j.1440-1827.1993.tb01126.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb01126.x","url":null,"abstract":"Hypoxic effects on glutamate uptake and ATP content in glial cells were investigated by using cultured C6 glioma cells. Mild regressive changes were found depending on the duration of the hypoxic insult, but necrosis or detachment of the cells from the substratum was rarely observed. Glutamate uptake was relatively well preserved after a short hypoxic insult, while a marked decrease in glutamate uptake was observed after hypoxia of long duration. The uptake of sucrose was reduced in a similar pattern to glutamate uptake. Hypoxic insult resulted in a significant reduction of the ATP content in glial cells. Therefore, the decrease in glutamate uptake by glial cells under hypoxia is likely to be due to ATP dependency, and not to the failure of a specific glutamate uptake system, but the failure of a general uptake of the glial cells owing to the energy-dependent membrane dysfunction by ATP depletion. These findings suggest that there are phased changes of astrocytic functions in a hypoxic condition, a preservative phase in the initial stages and then a dysfunctional phase in the later stages of hypoxia.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 4","pages":"154-9"},"PeriodicalIF":0.0,"publicationDate":"1993-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb01126.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19091523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Alveolar soft part sarcoma of the uterine cervix. 子宫颈肺泡软部肉瘤。

Acta pathologica japonica Pub Date : 1993-04-01 DOI: 10.1111/j.1440-1827.1993.tb01133.x

Y Morimitsu, H Tanaka, S Iwanaga, M Kojiro

引用次数: 6

Malignant nerve sheath tumor with rhabdomyoblastic differentiation arising from the acoustic nerve. 起源于听神经的恶性神经鞘肿瘤伴横纹肌母细胞分化。

Acta pathologica japonica Pub Date : 1993-04-01 DOI: 10.1111/j.1440-1827.1993.tb01132.x

M Maeda, T Jozaki, S Baba, H Muro, H Shirasawa, T Ichihashi

引用次数: 13

Carcinosarcoma of the prostate. 前列腺癌。

Acta pathologica japonica Pub Date : 1993-04-01 DOI: 10.1111/j.1440-1827.1993.tb01134.x

H Kubosawa, O Matsuzaki, Y Kondo, M Takao, N Sato

引用次数: 6

Co-carcinogenic effect of chrysotile and amosite asbestos with benzo(a)pyrene in the lung of hamsters. 温石棉和亚石棉与苯并(a)芘在仓鼠肺中的共同致癌作用。

Acta pathologica japonica Pub Date : 1993-04-01 DOI: 10.1111/j.1440-1827.1993.tb01125.x

G Kimizuka, M Azuma, M Ishibashi, K Shinozaki, Y Hayashi

{"title":"Co-carcinogenic effect of chrysotile and amosite asbestos with benzo(a)pyrene in the lung of hamsters.","authors":"G Kimizuka, M Azuma, M Ishibashi, K Shinozaki, Y Hayashi","doi":"10.1111/j.1440-1827.1993.tb01125.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb01125.x","url":null,"abstract":"To clarify co-carcinogenic effects of chrysotile (Chry) and amosite (Amo) asbestos with benzo(a)pyrene (Bap), 0.2 mg UICC (International Union against Cancer) standard reference sample of asbestos and 0.4 mg Bap were applied intratracheally once a week for 6 weeks. Eighteen and 24 months after the last instillation the number of tumors was examined. The Chry + Bap group yielded 37 tumors including 16 carcinomas in 12 animals, and the Amo + Bap group yielded 30 tumors including 11 carcinomas in 12 animals. Tumor-bearing animals were 100% in the Chry + Bap group and 92% in the Amo + Bap group, and carcinoma-bearing animals were 83% and 67%, respectively. The animals injected with Chry, Amo, and Bap alone developed no tumors. The number of tumors and carcinomas and the frequency of the tumor- or carcinoma-bearing animals in Chry + Bap and Amo + Bap were significantly higher than those of the groups injected independently. The number of tumors or the frequency of tumor-bearing animals was higher in Chry + Bap than in Amo + Bap; however, these differences were not significant. These results indicate that both Chry and Amo play an important role in the genesis of bronchogenic carcinoma.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 4","pages":"149-53"},"PeriodicalIF":0.0,"publicationDate":"1993-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb01125.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19373438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Anaplastic large cell lymphoma with histiocytic phenotypes. 具有组织细胞表型的间变性大细胞淋巴瘤。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01123.x

S Sakurai, T Nakajima, T Oyama, T Sano, Y Hosomura

引用次数: 2

Localization of E-cadherin adhesion molecules in human gingiva and gingival carcinoma. e -钙粘蛋白粘附分子在人牙龈和牙龈癌中的定位。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01117.x

T Sakaki, M Wato, S Otake, R Shirasu, A Tanaka

{"title":"Localization of E-cadherin adhesion molecules in human gingiva and gingival carcinoma.","authors":"T Sakaki, M Wato, S Otake, R Shirasu, A Tanaka","doi":"10.1111/j.1440-1827.1993.tb01117.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb01117.x","url":null,"abstract":"Immunohistochemical investigations were carried out on the localization and expression of the Ca(2+)-dependent intercellular adhesion molecule E-cadherin in human gingiva and gingival carcinoma. Although E-cadherin did not appear in the parakeratinized layer of either clinically healthy or inflamed gingiva, it did appear strongly in the prickle layer and somewhat more weakly in the basal layer. Immunogold particles reactive to anti-E-cadherin monoclonal antibody in the electron microscopic findings were localized only in the vicinity of the desmosomes of the prickle and basal layers. In the case of gingival carcinoma, although E-cadherin was strongly expressed in the cells surrounding the keratinized region in the cancer nests, the expression decreased towards the marginal portion of the cancer nests. The distribution of E-cadherin in these cells may be dependent on the condition of the cancer cells that are potentially invasive. These findings suggest that cells of the parakeratinized layer of gingiva and cells of the marginal portion of the gingival carcinoma nests may easily detach or invade. In addition, the findings suggest that the gingival carcinoma used in this study tended to be invasive.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 3","pages":"99-106"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb01117.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19466127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Cytometric analysis of testicular seminoma and spermatocytic seminoma. 睾丸精原细胞瘤和精原细胞瘤的细胞分析。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01120.x

H Takahashi

{"title":"Cytometric analysis of testicular seminoma and spermatocytic seminoma.","authors":"H Takahashi","doi":"10.1111/j.1440-1827.1993.tb01120.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb01120.x","url":null,"abstract":"DNA analysis of testicular seminoma (typical seminoma [TS] and anaplastic seminoma [AS]) and spermatocytic seminoma (SS) was performed to evaluate the relationship between the proliferative activity and clinical outcome, and also to determine the proliferative characteristics of SS. Nuclear DNA contents of 15 cases of TS, 17 of AS and three of SS were measured by flow cytometry. Cytofluorometric DNA analysis was performed on three cases of every tumor. All 35 cases showed aneuploidy in the flow cytometry. In comparison with TS, AS tended to have a higher percentage of G2M phase in one cell cycle, having more cell cycle numbers and containing cells of various DNA values. Many mitotic figures with larger atypical cells that characterize AS could be explained by these results. In SS, the diploid formation by the small cells and the appearance of large cells with a maximum DNA value of 40C were demonstrated. These ploidy characteristics were considered to result in the morphological expression of large, small and intermediate cells. The application of both flow cytometry and cytofluorometry to the same cases was beneficial.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 3","pages":"121-9"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb01120.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19466123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

EBER-1 expression in thymic carcinoma. 胸腺癌中EBER-1的表达。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01118.x

T Fujii, T Kawai, K Saito, K Fukushima, T Hasegawa, M Tokunaga, T Yokoyama

引用次数: 32