Acta pathologica japonica最新文献_第10页

Extracranial meningioma in the parapharyngeal space. 咽旁间隙的颅外脑膜瘤。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01121.x

S Mori, S Kobayashi, H Miki, E Hirakawa, R Haba, M Ohmori, M Miyaguchi

{"title":"Extracranial meningioma in the parapharyngeal space.","authors":"S Mori, S Kobayashi, H Miki, E Hirakawa, R Haba, M Ohmori, M Miyaguchi","doi":"10.1111/j.1440-1827.1993.tb01121.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb01121.x","url":null,"abstract":"A case of extracranial meningioma in the parapharyngeal space is reported. A 24 year old woman presented with swelling and tenderness of the parapharyngeal region. A tumor was palpable in this region, and the tumor was surgically removed. Macroscopically the tumor occurred from the portion between the axis and atlas. Histologically the tumor cells, which had oval nuclei and a slightly eosinophilic cytoplasm, proliferated in fibrous connective tissues to form small nests. As the cell borders were not clear, the tumor structure appeared to be syncytium-like. Immunohistochemically the tumor cells were positive for anti-vimentin antibodies, anti-S-100 protein antibodies and anti-epithelial membrane antigen (EMA) antibodies in part. Electron microscopically the tumor cells had complex interdigitations of their adjacent plasma membranes. These were studded with many desmosomes. Bundles of intermediate filaments were visible in the cytoplasm. On the basis of the clinical, histological, immunohistochemical and electron microscopical features, the tumor was diagnosed as extracranial meningotheliomatous meningioma. The parapharyngeal space is an extremely rare location for extracranial meningioma, and our case is the first in Japan as far as we know.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 3","pages":"130-4"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb01121.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19466124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Epstein-Barr virus-infected T cells in infectious mononucleosis. 感染性单核细胞增多症中eb病毒感染的T细胞。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01124.x

M Tokunaga, Y Uemura, T Tokudome, E Sato

{"title":"Epstein-Barr virus-infected T cells in infectious mononucleosis.","authors":"M Tokunaga, Y Uemura, T Tokudome, E Sato","doi":"10.1111/j.1440-1827.1993.tb01124.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb01124.x","url":null,"abstract":"Epstein-Barr virus (EBV) has been known as a B cell lymphotropic virus since the initial discovery of this virus in the cell lines established from Burkitt’s lymphoma (BL).’ EBV has been shown to cause infectious mononucleosis (IM), to be associated with BL and nasopharyngeal carcinoma, and to be linked to other neoplasms and polyclonal lymphoproliferative disorders in immunocompromized individuak2 EBV infects B lymphocytes by attachment to a cell surface receptor (c3d) of target cells. Some of these lymphocytes productively infected with EBV undergo lysis and do not survive, but others latently infected become immortalized and acquire the capacity to proliferate. EBV had not been thought to be associated with T cell lymphoma but recently the EBV genomes have been detected in neoplastic T cells, many of which expressed the CD8 p h e n ~ t y p e . ~ ~ We examined the lymph nodes of four patients with IM to determine the phenotypic expression of EBV-infected lymphocytes. Paraffin sections (3pm) were first stained by immunohistochemistry (IHC) using the alkaline phosphatase (ALP)-labeled avidin method employing primary antibodies of L26 (DAKO) as a B cell marker, CD3 (DAKO) as well as UCHL-1 (DAKO) as a T cell marker. They were stained bright red by the ALP reaction with naphthol-AS-BI phosphoric acid as a substrate and hexazotized new fuchsin as a coupler. In situ hybridization (ISH) was then performed using a digoxigenin-labeled oligonucleotide antisense probe for EBVencoded small RNA (EBER-1). The sections were treated with anti-digoxigenin alkaline phosphatase-conjugated antibody and then visualized with 5-bromo-4-chloro-3-indolyl phosphate (BCIP) and nitroblue tetrazorium salt (NTB) to produce purple-black signals. The sense probe and specimens of EBV-negative lymphadenitis were used as controls and gave completely negative results.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 3","pages":"146-7"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb01124.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19372790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Selective zonal change of the renomedullary interstitial cells in hypokalemic rats. 低钾血症大鼠肾髓间质细胞的选择性地带性改变。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01115.x

H Toyoshima, T Watanabe

引用次数: 0

Pulmonary hypertension due to tumor emboli: a report of three autopsy cases with morphological correlations to radiological findings. 肿瘤栓塞所致肺动脉高压:三例尸检报告，形态学与影像学表现相关。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01122.x

C Yutani, M Imakita, H Ishibashi-Ueda, M Katsuragi, T Yoshioka, T Kunieda

引用次数: 24

Cell kinetic and morphological studies of human cholangiocellular carcinoma. 人胆管细胞癌的细胞动力学和形态学研究。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01119.x

H Minato, Y Nakanuma

{"title":"Cell kinetic and morphological studies of human cholangiocellular carcinoma.","authors":"H Minato, Y Nakanuma","doi":"10.1111/j.1440-1827.1993.tb01119.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb01119.x","url":null,"abstract":"We investigated the cell kinetics and morphologies of cholangiocellular carcinoma (CCC) using 48 autopsied or surgically resected cases (47 were adenocarcinoma and the remaining adenosquamous cell carcinoma), all of which were formalin-fixed and paraffin-embedded. Cell kinetics were analyzed by counting the number of argyrophilic nucleolar organizer regions (AgNOR) using immunostaining of proliferating cell nuclear antigens (PCNA) and flow cytometric DNA analysis. Dedifferentiation of CCC was positively correlated with AgNOR number (2.22 +/- 0.21 in well differentiated, 3.66 +/- 0.85 in moderately differentiated and 4.17 +/- 0.49 in poorly differentiated adenocarcinomas, respectively). In 22 cases, the labeling index (LI) of PCNA was higher in moderately and poorly differentiated adenocarcinomas (24.0 +/- 2.35 and 26.0 +/- 4.89, respectively) than in well differentiated ones (10.8 +/- 2.14). A majority of well differentiated ones were diploid, while aneuploidy prevailed in moderately to poorly differentiated ones. These data suggest that cell proliferative indices and nuclear DNA analysis of CCC accurately reflect their histological grading. The anatomical location of CCC along the biliary tree had no relation to either of the cell kinetic data. In autopsy cases, the patients with organ and lymph node metastases tended to show a higher DNA index and aneuploidy. This study implies that a combination of several cell kinetic data is valuable for the evaluation of the biological behaviors of CCC, and also supports further studies of cell kinetics of CCC using small-sized biopsy specimens, as a prognostic indicator.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 3","pages":"111-20"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb01119.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19091033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

An epidemic outbreak of hepatitis E in Yangon of Myanmar: antibody assay and animal transmission of the virus. 缅甸仰光戊型肝炎疫情:抗体测定和病毒的动物传播。

Acta pathologica japonica Pub Date : 1993-03-01 DOI: 10.1111/j.1440-1827.1993.tb01116.x

T Uchida, T T Aye, X Ma, F Iida, T Shikata, M Ichikawa, T Rikihisa, K M Win

{"title":"An epidemic outbreak of hepatitis E in Yangon of Myanmar: antibody assay and animal transmission of the virus.","authors":"T Uchida, T T Aye, X Ma, F Iida, T Shikata, M Ichikawa, T Rikihisa, K M Win","doi":"10.1111/j.1440-1827.1993.tb01116.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb01116.x","url":null,"abstract":"An epidemic outbreak of hepatitis E occurred in an army recruit camp of Yangon, Myanmar, in October 1989. One hundred and eleven patients among 600 residents were hospitalized. As high as 83.7% of these patients were positive for the acute phase antibody against hepatitis E virus by an enzyme-linked immunosorbent assay developed in our laboratory. Also, 30.6% of 49 symptom-free residents examined were positive for the antibody. We prepared a stool extract from six patients and inoculated it into 10 rhesus monkeys for a series of three sub-passages. All of them developed acute biochemical hepatitis along with an elevation of antibody levels. A rechallenge with viruses of the present outbreak failed to provoke hepatitis in two monkeys that had previously recovered from acute hepatitis caused by an isolate of sporadic hepatitis E of the same area. Similarly, the rechallenge of the sporadic strain did not induce hepatitis in two monkeys that had been previously infected with the epidemic virus. These data suggested that the subjects would obtain neutralizing antibodies against the hepatitis E virus once infected, and many adult inhabitants of the endemic area had no protective antibodies and were still susceptible to hepatitis E infection.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 3","pages":"94-8"},"PeriodicalIF":0.0,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb01116.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19246050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 30

An autopsy case of cerebellar degeneration following lithium intoxication with neuroleptic malignant syndrome. 锂中毒后小脑变性伴抗精神病药恶性综合征尸检一例。

Acta pathologica japonica Pub Date : 1993-01-01 DOI: 10.1111/j.1440-1827.1993.tb02914.x

A Naramoto, N Koizumi, N Itoh, H Shigematsu

引用次数: 27

DNA ploidy and stromal bone formation as prognostic indicators of thyroid papillary carcinoma in aged patients: a retrospective study. DNA倍体和间质骨形成作为老年甲状腺乳头状癌预后指标的回顾性研究

Acta pathologica japonica Pub Date : 1993-01-01 DOI: 10.1111/j.1440-1827.1993.tb02910.x

H Yamashita, S Noguchi, N Murakami, K Tsuji, N Yamaoka, A Sakamoto

{"title":"DNA ploidy and stromal bone formation as prognostic indicators of thyroid papillary carcinoma in aged patients: a retrospective study.","authors":"H Yamashita, S Noguchi, N Murakami, K Tsuji, N Yamaoka, A Sakamoto","doi":"10.1111/j.1440-1827.1993.tb02910.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb02910.x","url":null,"abstract":"The prognostic value of flow cytometry for thyroid papillary carcinoma in aged patients was studied and compared with that of tumor histology. Seventy-five surgically removed primary papillary thyroid carcinomas larger than 30 mm in diameter were obtained from patients over 60 years of age. A subtotal thyroidectomy with modified radical neck dissection was performed in all patients. Sixteen female patients died of the carcinoma (non-survivors) and 18 survived longer than 12 years without recurrence (survivors). Histologically, papillary carcinoma was subclassified into poorly and well differentiated types, and the presence of stromal bone formation was noted. Flow cytometry was performed using paraffin-embedded materials. The incidence of the poorly differentiated type was 2/18 among the tumors of survivors and 6/16 among the tumors of non-survivors (P = 0.08). Stromal bone formation was only found in the tumors of the survivors (6/18 and 0/16; P = 0.014). In flow cytometry, tumors of the survivors showed a DNA diploid pattern (14/14), whereas half of the tumors of non-survivors (6/12) showed an aneuploid pattern (P = 0.004). Moreover, in the remaining six tumors of the non-survivors, two showed a third peak at 6C and one showed a higher S fraction. Therefore, only three showed a DNA diploid pattern that was indistinguishable from that of the survivors. These results suggest that flow cytometry is useful for estimating the prognosis of thyroid papillary carcinoma.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 1-2","pages":"22-7"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb02910.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19448685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Abscess-forming granulomatous lymphadenitis: histological typing of suppurative granulomas and clinicopathological findings with special reference to cat scratch disease. 脓肿性肉芽肿性淋巴结炎:化脓性肉芽肿的组织学分型和临床病理表现，特别参考猫抓病。

Acta pathologica japonica Pub Date : 1993-01-01 DOI: 10.1111/j.1440-1827.1993.tb02908.x

M Kojima, S Nakamura, Y Hosomura, K Shimizu, Y Kurabayashi, H Itoh, K Yoshida, Y Ohno, A Kaneko, S Asano

{"title":"Abscess-forming granulomatous lymphadenitis: histological typing of suppurative granulomas and clinicopathological findings with special reference to cat scratch disease.","authors":"M Kojima, S Nakamura, Y Hosomura, K Shimizu, Y Kurabayashi, H Itoh, K Yoshida, Y Ohno, A Kaneko, S Asano","doi":"10.1111/j.1440-1827.1993.tb02908.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb02908.x","url":null,"abstract":"In order to clarify the histological and immunohistochemical characteristics of suppurative granuloma in abscess-forming granulomatous lymphadenitis (AGL), and the relation between AGL and cat scratch disease (CSD), 36 cases of AGL were studied. The combined results showed that there were two types of suppurative granulomas. The suppurative granulomas histologically revealed small lymphocytes of predominantly T cell phenotype distributed among the epithelioid histiocytes bordering central necrotic areas in the suppurative granulomas. These suppurative granulomas could be further subdivided into two groups, mainly those with and without the intermingling of large transformed cells of B-cell phenotypes: Type B granuloma with large transformed B cells and Type A without large transformed B cells. Both types of granulomas were observed in a varying degree in most cases. According to the predominant type of granulomas, 36 patients with AGL were further classified into two groups: Group I of Type A dominance and Group II of Type B dominance. Warthin-Starry (WS) silver stain positive bacteria, which are said to be a causative agent of CSD, were present in about 50% of both groups. No Brown-Hopps' Gram-positive bacteria, fungus, toxoplasma, Chlamydia or Bacillus Calmette-Guérin antigen were found in any case. Clinically, there was no significant difference between these two groups. On the other hand, the detection of WS-positive bacteria seemed to have some relationship with the duration of disease and the history of exposure to cats, and 70% of AGL cases occurred in autumn without a single concurrent epidemic.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 1-2","pages":"11-7"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb02908.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18685709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Multiple penetrating colonic ulcers in secondary amyloidosis caused by rheumatoid arthritis. 类风湿关节炎致继发性淀粉样变性的多重穿透性结肠溃疡。

Acta pathologica japonica Pub Date : 1993-01-01 DOI: 10.1111/j.1440-1827.1993.tb02915.x

Y Ishikawa, T Ishii, S Masuda, N Asuwa, H Kiguchi

{"title":"Multiple penetrating colonic ulcers in secondary amyloidosis caused by rheumatoid arthritis.","authors":"Y Ishikawa, T Ishii, S Masuda, N Asuwa, H Kiguchi","doi":"10.1111/j.1440-1827.1993.tb02915.x","DOIUrl":"https://doi.org/10.1111/j.1440-1827.1993.tb02915.x","url":null,"abstract":"An autopsy case of multiple penetrated colonic ulcers with secondary amyloidosis caused by rheumatoid arthritis in a 61 year old woman is reported. Amyloid deposition was conspicuous in the transverse colon with numerous penetrating ulcers that were circumferentially scattered. Deposition was mainly in the small vessel walls of the submucosal layers. In the quantitative comparison of the histological components between the colonic segments affected by severe and mild ulcer formation, occlusive vascular amyloid deposition was revealed more frequently in the severe involved portion than in the mild involved portion. In addition, submucosal fibrosis that tended to appear around ulcers was more extensive and thicker in the former than in the latter. The complete vascular occlusion caused by amyloid deposition was particularly concentrated in the submucosal layer adjacent to the ulcer. These findings indicate that peripheral circulatory disturbance by amyloid deposition in the small vascular walls leads to ulcer formation in the colon.","PeriodicalId":75413,"journal":{"name":"Acta pathologica japonica","volume":"43 1-2","pages":"59-64"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1440-1827.1993.tb02915.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19448631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5