发布求助
文献互助 智能选刊 最新文献

Uirusu最新文献

筛选
英文 中文
[SARS-CoV-2 genomics and its application to genome surveillance]. [SARS-CoV-2基因组学及其在基因组监测中的应用]
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.147
Makoto Kuroda
{"title":"[SARS-CoV-2 genomics and its application to genome surveillance].","authors":"Makoto Kuroda","doi":"10.2222/jsv.70.147","DOIUrl":"https://doi.org/10.2222/jsv.70.147","url":null,"abstract":"","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 2","pages":"147-154"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39433993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hantavirus infection as a risk for chronic kidney disease of unknown etiology (CKDu) in Sri Lanka]. [汉坦病毒感染是斯里兰卡病因不明的慢性肾脏疾病(CKDu)的风险之一]。
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.175
Kumiko Yoshimatsu
{"title":"[Hantavirus infection as a risk for chronic kidney disease of unknown etiology (CKDu) in Sri Lanka].","authors":"Kumiko Yoshimatsu","doi":"10.2222/jsv.70.175","DOIUrl":"https://doi.org/10.2222/jsv.70.175","url":null,"abstract":"<p><p>Chronic kidney disease of unknown etiology (CKDu) has emerged in endemic areas of Sri Lanka since the 1990s. The disease is a chronic but fatal disease. Until now, heavy metals and agrochemicals have been suspected as the cause of CKDu, but it has been still unknown. Recently, we have found a high seroprevalence to hantavirus in CKDu patients and reported that hantavirus infection is a risk of CKDu. Hantaviruses are rodent-borne zoonotic viruses. Here, I would like to introduce a story of the research from sero-epidemiology to the search for host animals.</p>","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 2","pages":"175-184"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39433996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Virus-host coevolution: Endogenous RNA viral elements as pseudogenes]. [病毒-宿主共同进化:内源性RNA病毒元件作为假基因]。
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.49
Keizo Tomonaga
{"title":"[Virus-host coevolution: Endogenous RNA viral elements as pseudogenes].","authors":"Keizo Tomonaga","doi":"10.2222/jsv.70.49","DOIUrl":"https://doi.org/10.2222/jsv.70.49","url":null,"abstract":"<p><p>RNA viruses do not need to take the form of DNAs, and RNAs alone complete their replication cycles. On the other hand, since the 1970s, it has been known that DNA fragments derived from RNA viruses can be detected in RNA virus-infected cells. Furthermore, in this decade, it has become clear that the eukaryotic genomes contain genetic sequences derived from non-retroviral RNA viruses. The DNA sequences derived from these RNA viruses are thought to be generatedby using a transposable mechanism of retrotransposon, such as LINE-1. Many endogenous RNA viral sequences are formed by the same mechanism as processed pseudogenes in eukaryotic cells, but the significance of the production of RNA viral \"pseudogenes \" in infected cells has not been elucidated. We have discovered endogenous bornavirus-like elements (EBLs), which derived from a negative-sense, single-stranded RNA virus, Bornaviruses, and have studied the evolution and function of EBLs in host animals. The analysis of EBLs provides us a clue to unravel the history of host-RNA virus coexistence. In this review, I overview about the function of endogenous RNA virus sequences, especially EBLs in mammalian genomes, and discuss the significance of endogenization of RNA viruses as viral pseudogenes in evolution.</p>","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 1","pages":"49-56"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38883716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Massive nucleotide sequence data analysis reveals the nature of viruses]. [大量核苷酸序列数据分析揭示了病毒的本质]。
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.45
So Nakagawa
{"title":"[Massive nucleotide sequence data analysis reveals the nature of viruses].","authors":"So Nakagawa","doi":"10.2222/jsv.70.45","DOIUrl":"https://doi.org/10.2222/jsv.70.45","url":null,"abstract":"","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 1","pages":"45-48"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38883719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dynamic changes of cellular environment during Epstein-Barr virus productive replication]. [Epstein-Barr病毒高产复制期间细胞环境的动态变化]。
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.83
Yoshitaka Sato
{"title":"[Dynamic changes of cellular environment during Epstein-Barr virus productive replication].","authors":"Yoshitaka Sato","doi":"10.2222/jsv.70.83","DOIUrl":"https://doi.org/10.2222/jsv.70.83","url":null,"abstract":"<p><p>Productive (lytic) replication of DNA viruses elicits host cell DNA damage responses, which cause both beneficial and detrimental effects on viral replication. Viruses utilize them and selectively cancel the 'noisy' downstream signaling pathways, leading to maintain high S-phase CDK activities required for viral replication. To achieve this fine tuning of cellular environment, herpesviruses encode many (>70) genes in their genome, which are expressed in a strictly regulated temporal cascade (immediate-early, early, and late). Here, I introduce and discuss how Epstein-Barr virus, an oncogenic herpesvirus, hijacks the cellular environment and adapt it for the progeny production.</p>","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 1","pages":"83-90"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38883720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.185
Akihisa Kato, Yasushi Kawaguchi
{"title":"","authors":"Akihisa Kato,&nbsp;Yasushi Kawaguchi","doi":"10.2222/jsv.70.185","DOIUrl":"https://doi.org/10.2222/jsv.70.185","url":null,"abstract":"","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 2","pages":"185-190"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39433997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[African swine fever]. [非洲猪瘟]。
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.15
Takehiro Kokuho
{"title":"[African swine fever].","authors":"Takehiro Kokuho","doi":"10.2222/jsv.70.15","DOIUrl":"https://doi.org/10.2222/jsv.70.15","url":null,"abstract":"<p><p>African swine fever (ASF) is a hemorrhagic infectious disease of Suids, which is endemic in sub-Saharan area of African continent. ASF is usually circulating sub-symptomatically among wild species of Suidae family, such as warthogs and bush pigs, by mediating Ornithodoros soft ticks. Domestic pigs (Sus scrofa) are, however, highly sensitive to the infection and show severe clinical signs with a high mortality rate, resulting a huge impact on pork production. Currently, there is no treatment or vaccine available. The etiological agent, ASFV, is highly resistant to environmental conditions, and resides in unheated pork meat or pork meat products for a long period, which may be a chance of its long-distance spread. Since August 2018, ASFV has been circulating in East and Southeast Asian countries and may possibly be introduced into Japan. Here, I describe the outline of the disease and the etiology of the pathogen in order to remind the importance of \"awareness\" and \"preparedness\" for the disease.</p>","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 1","pages":"15-28"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38964407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[COVID-19: From a clinician's perspective.] [COVID-19:从临床医生的角度]
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.37
Satoshi Kutsuna
{"title":"[COVID-19: From a clinician's perspective.]","authors":"Satoshi Kutsuna","doi":"10.2222/jsv.70.37","DOIUrl":"https://doi.org/10.2222/jsv.70.37","url":null,"abstract":"<p><p>Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by SARS-CoV-2. As of March 30, 2020, there have been 693,224 reported patients with COVID-19 worldwide, with 1,446 in Japan. Currently, although aspects of the route of transmission are unclear, infection by contact and by inhaling droplets is considered to be the dominant transmission route. Inflammatory symptoms in the upper respiratory tract persist for several days to 1 week after onset, and in some patients symptoms of pneumonia worsen and become severe. The presence of underlying diseases and advanced age are risk factors for increased severity. Diagnosis is based on detection of SARS-CoV-2 by polymerase chain reaction (PCR) testing of nasopharyngeal swabs or sputum. Symptomatic management is the main treatment for this disease. Although the efficacy of several agents is currently being tested, at present there is no effective therapeutic agent. To prevent infection, in addition to standard preventive measures, measures that counteract infection by contact and droplet inhalation are important. In addition, if procedures that cause aerosolization of virus are used, then measures that prevent airborne infection should be implemented.</p>","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 1","pages":"37-44"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38883715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pathology and Immunology of COVID-19]. 【新冠肺炎病理与免疫学】。
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.167
Shun Iida, Tadaki Suzuki
{"title":"[Pathology and Immunology of COVID-19].","authors":"Shun Iida,&nbsp;Tadaki Suzuki","doi":"10.2222/jsv.70.167","DOIUrl":"https://doi.org/10.2222/jsv.70.167","url":null,"abstract":"<p><p>Since the first case of COVID-19 was reported from Wuhan, China in December 2019, SARS-CoV-2 has been spreading globally and has become major public health concern. At present, development of specific treatment for COVID-19 is in progress and several countermeasures have been subjected to clinical trials. However, efficacy of these countermeasures is limited. For development of effective medicines or vaccines against infectious diseases, it is mandatory to elucidate its etiology and pathogenesis by means of pathological analysis. Pathological studies revealed that the COVID-19 mainly affects respiratory tracts although other organs are also involved. In addition, immunological studies demonstrated that host immune response may exacerbates COVID-19 through systemic inflammation. In this review, we would like to overview pathology and immunology of COVID-19.</p>","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 2","pages":"167-174"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39433995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Development of hepatitis B virus culture systems]. 乙肝病毒培养系统的发展
Uirusu Pub Date : 2020-01-01 DOI: 10.2222/jsv.70.135
Yuichi Akahori, Makoto Hijikata
{"title":"[Development of hepatitis B virus culture systems].","authors":"Yuichi Akahori,&nbsp;Makoto Hijikata","doi":"10.2222/jsv.70.135","DOIUrl":"https://doi.org/10.2222/jsv.70.135","url":null,"abstract":"<p><p>Recent development of hepatitis B virus (HBV) culture systems has proceeded the molecular virological studies of the life cycle of HBV including infection step. However, the reproduction of HBV life cycle under the more physiological condition may be required to know the nature of HBV more precisely. The HBV culture system, we recently developed using immortalized human hepatocytes cultured in the three dimensional condition, seemed to be one of good tools for that purpose.</p>","PeriodicalId":75275,"journal":{"name":"Uirusu","volume":"70 2","pages":"135-146"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39433992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信