Rheumatology and immunology research最新文献_第9页

Social Media and its Impact on Rheumatology. 社交媒体及其对风湿病学的影响。

Rheumatology and immunology research Pub Date : 2022-12-31 eCollection Date: 2022-12-01 DOI: 10.2478/rir-2022-0026

William Hersh

引用次数: 0

How Twitter use in Rheumatology has Evolved. 风湿病学如何使用 Twitter？

Rheumatology and immunology research Pub Date : 2022-12-31 eCollection Date: 2022-12-01 DOI: 10.2478/rir-2022-0027

Irwin Lim

引用次数: 0

The Therapeutic Effect of Tacrolimus in a Mouse Psoriatic Model is Associated with the Induction of Myeloid-derived Suppressor Cells. 他克莫司在小鼠银屑病模型中的治疗效果与髓源性抑制细胞的诱导有关。

Rheumatology and immunology research Pub Date : 2022-12-01 DOI: 10.2478/rir-2022-0034

Shaokui Chen, Ping Liao, Long Xi, Yang Yang, Wenzhong Wu, Md Sahidul Islam, Zibei Lin, Ying Zheng, Xin Chen

{"title":"The Therapeutic Effect of Tacrolimus in a Mouse Psoriatic Model is Associated with the Induction of Myeloid-derived Suppressor Cells.","authors":"Shaokui Chen, Ping Liao, Long Xi, Yang Yang, Wenzhong Wu, Md Sahidul Islam, Zibei Lin, Ying Zheng, Xin Chen","doi":"10.2478/rir-2022-0034","DOIUrl":"https://doi.org/10.2478/rir-2022-0034","url":null,"abstract":"Objectives: Topical administration of Tacrolimus (TAC) is efective in the treatment of psoriasis in human patients and in mouse models. Previously, we showed that, though promoting the proliferative expansion of CD4+Foxp3+ regulatory T cells (Tregs), TNFR2 was protective in mouse psoriasis model. We thus examined the role of TNFR2 signal in the efect of TAC in the treatment of mouse psoriasis.Methods: To this end, psoriasis was induced in WT, or TNFR1 KO, or TNFR2 KO mice, and the psoriatic mice were treated with or without IMQ.Results: The results showed that TAC treatment potently inhibited the development of psoriasis in WT and TNFR1 KO mice, but not in TNFR2 KO mice. However, the treatment of TAC failed to induce the expansion of Tregs in psoriatic mice. In addition to playing a decisive role in the activation of Tregs, TNFR2 stimulates the generation and activation of myeloid-derived suppressor cells (MDSCs). This led us to found that the topical treatment with TAC markedly increased the number of MDSCs in the spleen of WT and TNFR1 KO mice, but not in TNFR2 KO mice. Consequently, TAC potently decreased serum levels of IL-17A, INF-γ, and TNF and their mRNA levels in the inflamed skin lesion.Conclusion: Therefore, our study for the first time found that the therapeutic efect of TAC in psoriasis is associated with the expansion of MDSCs in a TNFR2-dependent manner.","PeriodicalId":74736,"journal":{"name":"Rheumatology and immunology research","volume":"3 4","pages":"190-197"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/41/8b/rir-03-190.PMC9984933.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9424472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

#RheumTwitter - the Rise of Social Media in Rheumatology: Research, Collaboration, Education, and Engagement. #风湿病推特-风湿病学社交媒体的兴起:研究、合作、教育和参与。

Rheumatology and immunology research Pub Date : 2022-12-01 DOI: 10.2478/rir-2022-0030

Sasha Saadia Ali, Chris Wincup

{"title":"#RheumTwitter - the Rise of Social Media in Rheumatology: Research, Collaboration, Education, and Engagement.","authors":"Sasha Saadia Ali, Chris Wincup","doi":"10.2478/rir-2022-0030","DOIUrl":"https://doi.org/10.2478/rir-2022-0030","url":null,"abstract":"Social media broadly refers to an internet-based platform that allows for the online publication of content that is shared across a virtual community or network. Over recent years, there has been growing utilization of social media in the medical community. The field of rheumatology is no different. Social media allows for the sharing of information among rheumatologists, which can be useful in online education, disseminating research findings, forming new networks of collaborators, and discussing the latest advances in the field. However, there are several challenges facing clinicians using social media. As such, regulatory bodies have produced advisory codes of conduct to ensure better awareness concerning the appropriate use of social media among clinicians. In addition, clinicians (even those who do not use social media) need to be mindful of the fact that many patients will use these online platforms to find information, and with this comes the risk of false information. In this review, we highlight the benefits and challenges facing rheumatologists in relation to the world of social media.","PeriodicalId":74736,"journal":{"name":"Rheumatology and immunology research","volume":"3 4","pages":"163-168"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a3/1b/rir-03-163.PMC9984932.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9424473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Social Media and Rheumatology Societies: Strategic Insights. 社会媒体和风湿病学会:战略见解。

Rheumatology and immunology research Pub Date : 2022-12-01 DOI: 10.2478/rir-2022-0032

Dominique Alvarillo, Elena Nikiphorou

引用次数: 1

Bilateral Ureterohydronephrosis after Intestinal Pseudo-obstruction in a Patient with Systemic Lupus Erythematosus. 系统性红斑狼疮患者假性肠梗阻后双侧输尿管积水1例。

Rheumatology and immunology research Pub Date : 2022-12-01 DOI: 10.2478/rir-2022-0037

Wanting Qi, Yangzhong Zhou, Jiuliang Zhao

引用次数: 0

Social Media and the Patient - on Education and Empowerment. 社会媒体与患者——教育与赋权。

Rheumatology and immunology research Pub Date : 2022-12-01 DOI: 10.2478/rir-2022-0028

Geraldine T Zamora

引用次数: 2

Social Media for Research Discourse, Dissemination, and Collaboration in Rheumatology. 风湿病学研究话语、传播和合作的社会媒体。

Rheumatology and immunology research Pub Date : 2022-12-01 DOI: 10.2478/rir-2022-0031

Ariella Coler-Reilly, Elizabeth R Graef, Alfred H J Kim, Jean W Liew, Michael S Putman, Sebastian E Sattui, Kristen J Young, Jeffrey A Sparks

{"title":"Social Media for Research Discourse, Dissemination, and Collaboration in Rheumatology.","authors":"Ariella Coler-Reilly, Elizabeth R Graef, Alfred H J Kim, Jean W Liew, Michael S Putman, Sebastian E Sattui, Kristen J Young, Jeffrey A Sparks","doi":"10.2478/rir-2022-0031","DOIUrl":"https://doi.org/10.2478/rir-2022-0031","url":null,"abstract":"Social media has become an important venue for rheumatologists, patients, organizations, and other stakeholders to discuss recent research advances in diagnosis and management of rheumatic disorders. In this article, we describe the current state of how social media may enhance dissemination, discourse, and collaboration in rheumatology research. Social media may refer to social platforms like Twitter and Instagram or digital media like podcasts and other websites that are operated for providing as free, open-access medical education (FOAM). Twitter has been one of the most active social media venues and continues to host a vibrant rheumatology community. Examples of research discussions on Twitter include organic user tweets, educational threads (\"tweetorials\"), live-tweeting academic conferences, and journals posting recently-accepted articles. Some research collaborations have been initiated through social media interactions. Social media may also directly contribute to research by facilitating the recruitment of study participants and the collection of survey-based data. Thus, social media is an evolving and important tool to enhance research discourse, dissemination, and collaboration in rheumatology.","PeriodicalId":74736,"journal":{"name":"Rheumatology and immunology research","volume":"3 4","pages":"169-179"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/21/3f/rir-03-169.PMC9984924.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9118086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

RheumCloud App: A Novel Mobile Application for the Management of Rheumatic Diseases Patients in China. 风湿云App:中国风湿病患者管理的新型移动应用。

Rheumatology and immunology research Pub Date : 2022-12-01 DOI: 10.2478/rir-2022-0033

Can Huang, Jiuliang Zhao, Xinping Tian, Qian Wang, Dong Xu, Mengtao Li, Xiaofeng Zeng

引用次数: 1

Editorial for "Social Media in Rheumatology". “风湿病学的社交媒体”社论。

Rheumatology and immunology research Pub Date : 2022-12-01 DOI: 10.2478/rir-2022-0025

Priscilla C Wong, Yew Kuang Cheng

{"title":"Editorial for \"Social Media in Rheumatology\".","authors":"Priscilla C Wong, Yew Kuang Cheng","doi":"10.2478/rir-2022-0025","DOIUrl":"https://doi.org/10.2478/rir-2022-0025","url":null,"abstract":"The Asia Pacific League of Associations for Rheumatology (APLAR) Young Rheumatologists (AYR) group is a network of young rheumatologists in the Asia Pacific region united to move forward in education, collaboration, and research in the Asia Pacific and beyond. AYR is an integrated part of the APLAR community, representing the full spectrum of rheumatology. The AYR Board first organized a “Social Media in Rheumatology” symposium at the annual APLAR Congress in 2021. This pioneering educational activity connected aspiring young clinicians from different countries and regions (China, Hong Kong [special administrative region {SAR} of China], India, Pakistan, the Philippines, Sri Lanka, the United Arab Emirates, and the United Kingdom [UK]) to share their knowledge and experience on social media via focused presentations and live dialogue. The feedback was exemplary and has opened the gateway for future collaboration among different societies of rheumatology. In this special edition covering “Social Media in Rheumatology”, AYR proudly further presents this impactful theme for our rheumatology community. We are honored and very excited to collaborate with several impassioned young academics from the Emerging European League Against Rheumatism (EULAR) NETwork (EMEUNET) and the American College of Rheumatology (ACR) in this particular issue. As citizens of the","PeriodicalId":74736,"journal":{"name":"Rheumatology and immunology research","volume":"3 4","pages":"149-150"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e8/72/rir-03-149.PMC9984935.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10850211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0