{"title":"肉芽肿合并多血管炎患者支气管异常肿块和“鹅卵石样”改变。","authors":"Ping Fan, Zhiming Hao, Peilong Cao, Lan He","doi":"10.2478/rir-2023-0007","DOIUrl":null,"url":null,"abstract":"A 44-year-old male was diagnosed with granulomatosis with polyangiitis (GPA) 1 year ago because of intermittent cough, short of breath, epistaxis, hearing loss and a positive protein-ase-3 anti-neutrophilic cytoplasmatic antibody (PR3-ANCA) test. After being treated with oral prednisone, cyclophospha-mide for a year, he was hospitalized due to reappearance of cough and epistaxis. The nasopharyngoscopy showed extensive necrosis of the left nasal cavity. The biopsy of nasal cavity mucosa revealed fibrinoid necrotizing vasculitis","PeriodicalId":74736,"journal":{"name":"Rheumatology and immunology research","volume":"4 1","pages":"44-45"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/d1/rir-4-1-rir-2023-0007.PMC10150860.pdf","citationCount":"0","resultStr":"{\"title\":\"Unusual presentation of a mass and \\\"cobble-stone like\\\" changes in the bronchus of a patient with granulomatosis with polyangitis.\",\"authors\":\"Ping Fan, Zhiming Hao, Peilong Cao, Lan He\",\"doi\":\"10.2478/rir-2023-0007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A 44-year-old male was diagnosed with granulomatosis with polyangiitis (GPA) 1 year ago because of intermittent cough, short of breath, epistaxis, hearing loss and a positive protein-ase-3 anti-neutrophilic cytoplasmatic antibody (PR3-ANCA) test. After being treated with oral prednisone, cyclophospha-mide for a year, he was hospitalized due to reappearance of cough and epistaxis. The nasopharyngoscopy showed extensive necrosis of the left nasal cavity. The biopsy of nasal cavity mucosa revealed fibrinoid necrotizing vasculitis\",\"PeriodicalId\":74736,\"journal\":{\"name\":\"Rheumatology and immunology research\",\"volume\":\"4 1\",\"pages\":\"44-45\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/99/d1/rir-4-1-rir-2023-0007.PMC10150860.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rheumatology and immunology research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2478/rir-2023-0007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rheumatology and immunology research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/rir-2023-0007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Unusual presentation of a mass and "cobble-stone like" changes in the bronchus of a patient with granulomatosis with polyangitis.
A 44-year-old male was diagnosed with granulomatosis with polyangiitis (GPA) 1 year ago because of intermittent cough, short of breath, epistaxis, hearing loss and a positive protein-ase-3 anti-neutrophilic cytoplasmatic antibody (PR3-ANCA) test. After being treated with oral prednisone, cyclophospha-mide for a year, he was hospitalized due to reappearance of cough and epistaxis. The nasopharyngoscopy showed extensive necrosis of the left nasal cavity. The biopsy of nasal cavity mucosa revealed fibrinoid necrotizing vasculitis
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