Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo最新文献

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Michigan appropriateness guide for intravenous catheters in pediatrics - miniMAGIC-Brasil: translation into Brazilian portuguese. 密歇根州儿科静脉导管适宜性指南 - miniMAGIC-Brasil:翻译成巴西葡萄牙语。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-05-13 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023159
Marcelle Di Angelis Ambar Felipe, Maria Angelica Sorgini Peterlini, Amanda Ullman, Mavilde da Luz Gonçalves Pedreira
{"title":"Michigan appropriateness guide for intravenous catheters in pediatrics - miniMAGIC-Brasil: translation into Brazilian portuguese.","authors":"Marcelle Di Angelis Ambar Felipe, Maria Angelica Sorgini Peterlini, Amanda Ullman, Mavilde da Luz Gonçalves Pedreira","doi":"10.1590/1984-0462/2024/42/2023159","DOIUrl":"10.1590/1984-0462/2024/42/2023159","url":null,"abstract":"<p><strong>Objective: </strong>To perform the translation and adaptation of the Michigan Appropriateness Guide for Intravenous Catheters in Pediatrics (miniMAGIC) into Brazilian Portuguese.</p><p><strong>Methods: </strong>Methodological study performed in five recommended stages: initial translations; synthesis of the translations; back translations; assessment of the back translations; expert committee assessment. The expert committee was composed of three registered nurses and two doctors who had a Master's and/or PhD degree, and an expertise in intravenous therapy and pediatric and neonatal care. To assess the semantic, idiomatic, experiential and conceptual adequacy, a Likert scale was applied, in which 1, \"not equivalent\"; 2, \"inequivalent\"; 3, \"cannot assess\"; 4, \"quite equivalent\"; 5, \"totally equivalent\". The terms mostly analyzed as negative in equivalence and with a lower than 20 score were reviewed and submitted to a new assessment, with the Delphi Technique until consensus was obtained. The results were stored in electronic spreadsheets and treated with concordance index, with a minimum acceptable result of 0.80.</p><p><strong>Results: </strong>The content of all recommendations, named as miniMAGIC-Brasil, was validated by the expert committee after two stages of evaluation. All recommendations had an overall agreement index of 0.91.</p><p><strong>Conclusions: </strong>The miniMAGIC-Brazil guide was validated in respect to the adequacy of the translation after two steps.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023159"},"PeriodicalIF":0.0,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11095236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adolescents with orofacial clefts: understanding their experiences. 患有口面裂的青少年:了解他们的经历。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-05-06 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023131
Marina Gifalli, Camila Trettene Antonio, Verônica Aparecida Pezzato da Silva, Francine Aroteia Capone, Priscila Capelato Prado, Armando Dos Santos Trettene
{"title":"Adolescents with orofacial clefts: understanding their experiences.","authors":"Marina Gifalli, Camila Trettene Antonio, Verônica Aparecida Pezzato da Silva, Francine Aroteia Capone, Priscila Capelato Prado, Armando Dos Santos Trettene","doi":"10.1590/1984-0462/2024/42/2023131","DOIUrl":"10.1590/1984-0462/2024/42/2023131","url":null,"abstract":"<p><strong>Objective: </strong>To understand the experience of young people with orofacial clefts regarding life as an adolescent.</p><p><strong>Methods: </strong>Descriptive, qualitative study, developed in a Brazilian public and tertiary hospital, a reference center in the care of patients with craniofacial anomalies and related syndromes, between February and April 2019. The sample was defined by theoretical saturation. The following inclusion criteria were established: age between ten and 19 years old and having previously operated on orofacial cleft (lip and/or palate). Individuals with fissure associated with syndromes or other malformations were excluded. Data collection was performed through semi-structured interviews, which were audio recorded and transcribed in full. The trigger element was: how has it been for you to experience your adolescence? For the construction of the results, content analysis was used in the thematic modality.</p><p><strong>Results: </strong>Seventeen adolescents participated. From the speeches, three categories were revealed: interacting socially, feeling supported, and experiencing and facing prejudice.</p><p><strong>Conclusions: </strong>The biopsychosocial and conflicting complexity that adolescents with orofacial clefts experience was noticed, as well as the importance of receiving support and establishing modalities of situational coping.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023131"},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11073468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140878064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual scanning of social stimuli in preterm and autism spectrum disorder children. 早产儿和自闭症谱系障碍儿童对社交刺激的视觉扫描。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-05-06 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023017
Vivian Renne Gerber Lederman, Ana Lucia Goulart, Juliana Gioia Negrão, José Salomão Schwartzman
{"title":"Visual scanning of social stimuli in preterm and autism spectrum disorder children.","authors":"Vivian Renne Gerber Lederman, Ana Lucia Goulart, Juliana Gioia Negrão, José Salomão Schwartzman","doi":"10.1590/1984-0462/2024/42/2023017","DOIUrl":"10.1590/1984-0462/2024/42/2023017","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the pattern of eye-gaze of preterm (PT), autism spectrum disorder (ASD) and neurotypical (Ty) children.</p><p><strong>Methods: </strong>A cross-sectional study with eight preterm (born with ≤2000 g weight), nine ASD and five Ty male children, between six and nine years old, was performed. The eye gaze was evaluated presenting a board with a couple in social interaction, and a video with four children playing with blocks, projected in a screen computer, successively, evaluating the time that the children looked at each stimulus.</p><p><strong>Results: </strong>Although all the groups focus on the central social figure with no significant differences, ASD presented significant differences in time fixation of the objects (p=0.021), while premature children fixated more time in the central social interaction than in the whole scene than typical children.</p><p><strong>Conclusions: </strong>Although this study found noteworthy differences in the eye-gaze patterns among the three groups, additional research with a more extensive participant pool is necessary to validate these preliminary results.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023017"},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11073467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140878065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding child development and care integrality: Primary Health Care doctors and nurses' view. 了解儿童发展和护理的整体性:初级保健医生和护士的观点。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-04-29 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023127
Catarina Falleiros Nogueira Rojas, Danielle Abdel Massih Pio, Ana Carolina Nonato
{"title":"Understanding child development and care integrality: Primary Health Care doctors and nurses' view.","authors":"Catarina Falleiros Nogueira Rojas, Danielle Abdel Massih Pio, Ana Carolina Nonato","doi":"10.1590/1984-0462/2024/42/2023127","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023127","url":null,"abstract":"<p><strong>Objective: </strong>To identify perceptions of primary care health professionals regarding the conceptual aspects of child development and propose strategies to address difficulties.</p><p><strong>Methods: </strong>This descriptive-analytical study was conducted in a small municipality in the countryside of the State of São Paulo, Brazil. The primary health care in this region is comprised of Family Health Units and Basic Health Units. The sample included 52 participants, consisting of doctors and primary care nurses. A questionnaire with open and closed questions was utilized, covering knowledge and practices related to child development. For this study, the first question of the questionnaire, which asked for a descriptive response about participants' understanding of child development, was employed. The responses were transcribed, and content analysis using the thematic approach was conducted.</p><p><strong>Results: </strong>Among the participants, 54% were nurses, and the average duration of working with the pediatric population was ten years. 80% reported never having undergone training in child development. The analysis of the responses revealed heterogeneity in the professionals' understanding of the conceptual dimension of child development. Additionally, there was an insufficient grasp of the theoretical and practical aspects and a scarcity of resources to support comprehensive care for children. A predominant biomedical model focusing on disease and biological aspects of child health was evident in defining the understanding of the subject.</p><p><strong>Conclusions: </strong>The findings underscore the necessity of implementing health education initiatives and service projects in primary care settings. It is crucial to strengthen a comprehensive perspective of child health within the biopsychosocial model of the health-disease process.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023127"},"PeriodicalIF":0.0,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Third stage of the kangaroo method: exclusive breastfeeding and growth of preterm and/or low birth weight newborns. 袋鼠法的第三阶段:纯母乳喂养与早产儿和/或低出生体重儿的成长。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-04-29 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023141
Sandra Lima Ornelas, Rafael Paim Guimarães, Lorena Almeida Silva, Roberta Maia de Castro Romanelli, Maria Cândida Ferrarez Bouzada
{"title":"Third stage of the kangaroo method: exclusive breastfeeding and growth of preterm and/or low birth weight newborns.","authors":"Sandra Lima Ornelas, Rafael Paim Guimarães, Lorena Almeida Silva, Roberta Maia de Castro Romanelli, Maria Cândida Ferrarez Bouzada","doi":"10.1590/1984-0462/2024/42/2023141","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023141","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the rates of exclusive breastfeeding (EBF) and growth of preterm and/or low birth weight newborns during the third stage of the Kangaroo Method (TSKM), at discharge.</p><p><strong>Methods: </strong>Retrospective study in a reference public maternity hospital between Jan/2014 and Dec/2017, including the preterm (less than 37 weeks) and/or low birth weight (less than 2500 g) newborn infants. Information was collected from medical records. Statistics analysis was done in SPSS software.</p><p><strong>Results: </strong>482 infants were included and followed up at the TSKM ambulatory. The average gestational age was 33 weeks (variation: 24-39 weeks) and birth weight, 1715g (variation: 455-2830 g). EBF occurred in 336 (70.1%) infants at hospital discharge, and in 291 (60.4%) at TSKM discharge. Each additional day of hospital stay increased the chance of infant formula (IF) use by 9.3% at hospital discharge and by 10.3% at TSKM discharge. Staying in the Kangaroo Neonatal Intermediate Care Unit (KNICU) favored EBF at hospital discharge and TSKM discharge (p<0.001). Not performing the kangaroo position increased the chance formula administration to the newborn infant at hospital discharge by 11%. Weight gain and head circumference growth were higher in infants using formula (p<0.001).</p><p><strong>Conclusions: </strong>The length of hospital stay and not performing the kangaroo position favored the use of infant formula at hospital and TSKM discharge. Staying in the KNICU favored exclusive breastfeeding at hospital and TSKM discharge. Weight gain and HC growth were higher in newborns receiving infant formula.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023141"},"PeriodicalIF":0.0,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140857426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life after necrotizing enterocolitis: an integrative review. 坏死性小肠结肠炎后的生活质量:综合综述。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-04-29 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023188
Breno Oliveira Marques, Ana Beatriz Ferreira Gusmão, Luana Leal Gonzaga, Gabriela Garcia de Carvalho Laguna, Níkolas Brayan da Silva Bragas, Camila da Palma Maltez Monção, Natália Oliveira E Silva
{"title":"Quality of life after necrotizing enterocolitis: an integrative review.","authors":"Breno Oliveira Marques, Ana Beatriz Ferreira Gusmão, Luana Leal Gonzaga, Gabriela Garcia de Carvalho Laguna, Níkolas Brayan da Silva Bragas, Camila da Palma Maltez Monção, Natália Oliveira E Silva","doi":"10.1590/1984-0462/2024/42/2023188","DOIUrl":"10.1590/1984-0462/2024/42/2023188","url":null,"abstract":"<p><strong>Objective: </strong>To describe the long-term health outcomes of neonates affected by necrotizing enterocolitis (NEC) and its implications for quality of life.</p><p><strong>Data source: </strong>This is an integrative review, conducted by searching the literature in the following databases: Virtual Health Library (BVS), Latin American and Caribbean Health Sciences Literature (LILACS), Medical Literature Analysis and Retrieval System Online (MEDLINE), and PubMed, using Health Sciences Descriptors (DeCS): \"necrotizing enterocolitis,\" \"quality of life,\" and \"prognosis\" combined with the Boolean operators AND and OR: \"quality of life\" OR \"prognosis.\" Inclusion criteria were: publication period between 2012 and 2022.</p><p><strong>Data synthesis: </strong>A total of 1,010 studies were located, of which ten were selected to comprise the bibliographic sample of this review. Children with NEC are prone to exhibit cognitive neurological impairment, especially those who undergo surgical procedures due to more severe conditions. Motor development was considered below average when compared to healthy children, with more noticeable delays in fine and gross motor function development. The search for the relationship between NEC and quality of life revealed that this condition has a negative impact on the well-being of affected individuals.</p><p><strong>Conclusions: </strong>NEC has proven to be a serious condition contributing to high rates of morbidity and mortality in newborns, potentially leading to a reduction in the quality of life of affected patients.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023188"},"PeriodicalIF":0.0,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140866966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-cultural adaptation of the Neonatal Medical Index (NMI) to Brazil. 在巴西对新生儿医学指数(NMI)进行跨文化调整。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-04-29 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023164
Marcelo Dias, Silvana Alves Pereira, Roberta Costa, Sérgio Tadeu Martins Marba, Dayane Montemezzo
{"title":"Cross-cultural adaptation of the Neonatal Medical Index (NMI) to Brazil.","authors":"Marcelo Dias, Silvana Alves Pereira, Roberta Costa, Sérgio Tadeu Martins Marba, Dayane Montemezzo","doi":"10.1590/1984-0462/2024/42/2023164","DOIUrl":"https://doi.org/10.1590/1984-0462/2024/42/2023164","url":null,"abstract":"<p><strong>Objective: </strong>To perform a cross-cultural adaptation and assess the content validity of the Neonatal Medical Index (NMI) for the Brazilian context.</p><p><strong>Methods: </strong>The cross-cultural adaptation was completed in six steps, including translation, synthesis of translations, back translation, submission to an expert committee, testing of the prefinal version, and appraisal by the original author. The expert committee assessed the equivalence between versions based on the percentage of agreement, and content validity was evaluated using the content validity index (CVI) for each item of the scale (I-CVI) and for the overall scale (S-CVI) in terms of representativeness and clarity. Participants of the prefinal version also evaluated the CVI for clarity.</p><p><strong>Results: </strong>After two evaluation rounds of the expert committee it was attained 98% agreement, attesting to the equivalence between the instrument versions, maximum values for representativeness I-CVI and S-CVI/Ave (1.00), and high values for clarity I-CVI (all items ≥0.97) and S-CVI/Ave (0.98). The expert committee members defined that the Brazilian version of the instrument would be called Índice Clínico Neonatal (NMI-Br). The NMI-Br reached high values of CVI for clarity (all I-CVI ≥0.86 and S-CVI/Ave=0.99) among the participants of the prefinal version.</p><p><strong>Conclusions: </strong>The NMI-Br is the Brazilian version of the NMI, obtained in a rigorous cross-cultural validation process, counting with adequate values of content validity.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023164"},"PeriodicalIF":0.0,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11059933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The state of the art in therapeutic administration of botulinum toxin in children with cerebral palsy: an integrative review. 脑瘫儿童肉毒杆菌毒素治疗应用的最新进展:综述。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-03-25 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023093
Sandro Rachevsky Dorf, Adriana Rodrigues Fonseca, Flávio Roberto Sztajnbok, Thiffany Rodrigues Delfino de Oliveira, Linamara Rizzo Basttistella
{"title":"The state of the art in therapeutic administration of botulinum toxin in children with cerebral palsy: an integrative review.","authors":"Sandro Rachevsky Dorf, Adriana Rodrigues Fonseca, Flávio Roberto Sztajnbok, Thiffany Rodrigues Delfino de Oliveira, Linamara Rizzo Basttistella","doi":"10.1590/1984-0462/2024/42/2023093","DOIUrl":"10.1590/1984-0462/2024/42/2023093","url":null,"abstract":"<p><strong>Objective: </strong>To describe the current state of the art in the therapeutic administration of botulinum toxin with indications, efficacy, and safety profile for children and adolescents with cerebral palsy.</p><p><strong>Data source: </strong>An integrative review was conducted. The MEDLINE/PubMed database was searched twice within the last decade using distinct terms, and only studies written in the English language were included. The study population was limited to those aged 0-18 years. Articles that were duplicates or lacked sufficient methodology information were excluded.</p><p><strong>Data synthesis: </strong>We found 256 articles, of which 105 were included. Among the included studies, most were conducted in developed countries. Botulinum toxin demonstrated good safety and efficacy in reducing spasticity, particularly when administered by a multidisciplinary rehabilitation team. It is primarily utilized to improve gait and upper limb function, facilitate hygiene care, reduce pain, prevent musculoskeletal deformities, and even decrease sialorrhea in patients without a functional prognosis for walking.</p><p><strong>Conclusions: </strong>The administration of botulinum toxin is safe and efficacious, especially when combined with a multi-professional rehabilitation team approach, which increases the probability of functional improvement. It can also be beneficial for patients with significant functional impairments to help with daily care tasks, such as hygiene, dressing, and reducing sialorrhea. Pediatricians must be familiar with this treatment and its indications to attend to and refer patients promptly when necessary, and to exploit their neuroplasticity. Further research on this topic is required in developing countries.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023093"},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10962635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polyphenol analysis in human milk by a rapid, cost-effective, and accurate micromethod: translational development. 利用快速、经济、准确的微量法分析母乳中的多酚:转化开发。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-03-25 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023186
Mariela Valentina Cortez, Ana Veronica Scotta, Agustín Ramiro Miranda, Elio Andrés Soria
{"title":"Polyphenol analysis in human milk by a rapid, cost-effective, and accurate micromethod: translational development.","authors":"Mariela Valentina Cortez, Ana Veronica Scotta, Agustín Ramiro Miranda, Elio Andrés Soria","doi":"10.1590/1984-0462/2024/42/2023186","DOIUrl":"10.1590/1984-0462/2024/42/2023186","url":null,"abstract":"<p><strong>Objective: </strong>To develop a rapid method for analysing polyphenols, which are potentially active antioxidants against neonatal oxidative stress, from small human milk (HM) volumes.</p><p><strong>Methods: </strong>Acid and alkaline extractions were compared using two dyes: Folin-Ciocalteu and Fast Blue BB. Linearity, sensitivity, recovery percentage, polyphenol content, precision, and stability were assessed in 14 HM samples and compared using the Kruskal-Wallis H test (p<0.05). The best technique was applied to 284 HM samples to determine their polyphenolic content and its association with maternal diet by multifactorial linear regression.</p><p><strong>Results: </strong>Acidic extraction successfully recovered the gallic acid reference standard, whereas alkaline extraction overestimated it. Calibration curves for all methods were linear (R2>0.96) up to 500 mg/L. All bicarbonate-based Folin-Ciocalteu methods assayed were stable and repeatable, whereas Fast Blue BB-based variants were not. HM polyphenols (mean=94.68 mg/L) positively correlated to the dietary intake of hydroxycinnamic acids, the most consumed polyphenolic family in this population.</p><p><strong>Conclusions: </strong>A bicarbonate-based Folin-Ciocalteu micromethod allowed the accurate determination of polyphenols in HM, which might be useful for translational research settings and HM banks.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023186"},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10962630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Translation and measurement properties of the Portuguese-Brazil version of the Hammersmith Infant Neurological Examination (HINE-Br). 葡萄牙-巴西版哈默史密斯婴儿神经系统检查(HINE-Br)的翻译和测量特性。
Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo Pub Date : 2024-03-25 eCollection Date: 2024-01-01 DOI: 10.1590/1984-0462/2024/42/2023105
Michelle Alexandrina Dos Santos Furtado, Hércules Ribeiro Leite, Matheus Rocha Pereira Klettenberg, Victor Alves Rodrigues, Lisiane Seguti Ferreira, Melina Rodero Marques, Isadora de Oliveira Cavalcante, Tamires Saboia Santos, Tathiana Ghisi de Souza, Ayrles Silva Gonçalves Barbosa Mendonça, Ana Cristina Resende Camargos, Kênnea Martins Almeida Ayupe
{"title":"Translation and measurement properties of the Portuguese-Brazil version of the Hammersmith Infant Neurological Examination (HINE-Br).","authors":"Michelle Alexandrina Dos Santos Furtado, Hércules Ribeiro Leite, Matheus Rocha Pereira Klettenberg, Victor Alves Rodrigues, Lisiane Seguti Ferreira, Melina Rodero Marques, Isadora de Oliveira Cavalcante, Tamires Saboia Santos, Tathiana Ghisi de Souza, Ayrles Silva Gonçalves Barbosa Mendonça, Ana Cristina Resende Camargos, Kênnea Martins Almeida Ayupe","doi":"10.1590/1984-0462/2024/42/2023105","DOIUrl":"10.1590/1984-0462/2024/42/2023105","url":null,"abstract":"<p><strong>Objective: </strong>The current study aimed to translate the Hammersmith Infant Neurological Examination (HINE) into Brazilian Portuguese and analyze the reliability of the translated version for a population of Brazilian infants.</p><p><strong>Methods: </strong>This was a methodological study, approved by the Ethics Committee, carried out between June 2020 and May 2021. HINE is a standardized clinical neurological examination used for the early detection of cerebral palsy. The quantitative section, \"neurological examination\", contains 26 items scored from 0 to 3 points, divided into five categories: cranial nerve function, posture, movements, muscle tone and reflexes, and reactions. The HINE translation followed four steps: translation, synthesis, back-translation, and evaluation by an expert committee. To verify the reliability of the HINE-Br (Portuguese-Brazil version) two independent examiners evaluated 43 infants, between 3 and 22 months of age. Internal consistency was verified by Cronbach's Alpha coefficient and interrater reliability by the intraclass correlation coefficient (ICC).</p><p><strong>Results: </strong>The translated version was similar to the original version and a few semantic and idiomatic adjustments were necessary. Appropriate internal consistency (Alpha=0.91) was found for the 26 items of the HINE-Br, as well as strong interrater reliability for the total score (ICC2.1=0.95), and also for the five categories (ICC2.1=0.83-0.95).</p><p><strong>Conclusions: </strong>The HINE-Br presents adequate rates of internal consistency and interrater reliability, and can be used for the evaluation of children at risk for cerebral palsy, between 3 and 24 months of age, by pediatricians and pediatric physical therapists.</p>","PeriodicalId":74721,"journal":{"name":"Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo","volume":"42 ","pages":"e2023105"},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10962631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140308170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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