Revista de gastroenterologia de Mexico (English)最新文献

{"title":"Predictive mortality scale in AML-associated neutropenic enterocolitis: A systematic review of the literature","authors":"R. Zayas-Bórquez,&nbsp;J. Canto-Losa,&nbsp;M. García-Maldonado,&nbsp;N. Salgado-Nesme,&nbsp;O. Santes","doi":"10.1016/j.rgmxen.2025.07.003","DOIUrl":"10.1016/j.rgmxen.2025.07.003","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Neutropenic enterocolitis (NE) is a severe complication in immunocompromised patients, especially those with acute myeloid leukemia (AML) receiving intensive chemotherapy treatment. Despite medical advances, NE continues to be associated with a high mortality rate, particularly when its diagnosis and treatment are delayed. The present study aimed to identify the risk factors linked to mortality in patients with NE and develop a predictive scale for optimizing clinical decisions.</div></div><div><h3>Materials and methods</h3><div>A systematic review was conducted in accordance with the PRISMA 2020 guidelines and included 24 clinical studies (n = 1,172). Factors associated with in-hospital mortality were identified through odds ratio (OR) and relative risk (RR), with a 95% confidence interval (CI), and bivariate statistical tests, such as the chi-square and Fisher’s exact tests (p &lt; 0.05). A predictive scale was constructed based on said factors. A meta-analysis was carried out, using the DerSimonian and Laird random effects model for evaluating granulocyte colony-stimulating factor (G-CSF) as a protective factor, with heterogeneity (I²) and leave-one-out sensitivity tests. Quality of evidence was evaluated using the GRADE system.</div></div><div><h3>Results</h3><div>The overall mortality rate was 23.6%. The identified predictors of greater mortality were profound neutropenia, comorbidities, concomitant infection, admission to the intensive care unit, late diagnosis, age ≥60 years, and absence of G-CSF use. The meta-analysis yielded a combined OR of 0.68 (95% CI 0.62−0.72; I² = 0 %) in favor of G-CSF use. Factors with no statistical significance or affected by indication bias, such as surgery or cytarabine, were excluded. The resulting scale stratifies patients into four risk categories, with estimated mortality rates of ≤10%, 11–30%, 31–50%, and &gt;50%.</div></div><div><h3>Conclusion</h3><div>An exploratory mortality risk scale for patients with NE and AML, constructed from aggregate data and systematic evidence, is presented herein. Even though it yielded statistical robustness and clinical plausibility, the scale should not be employed for making clinical decisions until it has been prospectively validated in independent cohorts with multivariate adjustment.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 163-170"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical management of cystic neoplasms of the pancreas: 22 years of experience at a tertiary care hospital in Mexico","authors":"J. Canto-Losa,&nbsp;C. Moreno-Licea,&nbsp;J.J. Rosales-de la Rosa,&nbsp;E. Ramírez-García,&nbsp;C. Chan,&nbsp;I. Domínguez-Rosado","doi":"10.1016/j.rgmxen.2026.05.002","DOIUrl":"10.1016/j.rgmxen.2026.05.002","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Cystic neoplasms of the pancreas (CNPs) are diverse lesions that are a diagnostic and therapeutic challenge. Even though they are rare, the frequency of their diagnosis has increased with the advances made in imaging techniques. The identification and adequate characterization of these lesions is essential for determining the need for surgical intervention and individual patient follow-up. The primary aim of the present study was to describe the clinical and histopathologic characteristics of the CNPs resected over a 22-year period at a Mexican referral center, along with their postoperative results.</div></div><div><h3>Material and methods</h3><div>A retrospective, observational study was conducted on 139 patients who underwent surgical resection within the time frame of January 2000 and December 2022. The clinical and histopathologic characteristics and 30-day postoperative outcomes were described, comparing them, based on histologic subtypes and the surgical techniques employed.</div></div><div><h3>Results</h3><div>Most of the CNPs were solid pseudopapillary neoplasms (SPNs) (35.3%), followed by mucinous cystadenoma (32.4%), and serous cystadenoma (16.5%). The postoperative complication rate was 39.6%, and was higher in patients who underwent pancreatoduodenectomy, compared with the rest of the techniques (53.5 vs 33.3%, <em>p</em> = 0.038). There were no differences between histologic subtypes.</div></div><div><h3>Conclusions</h3><div>Precise classification of CNPs is crucial for adequate management. The higher frequency of diagnosis appears to be due to improved imaging techniques, enabling the timely identification of pancreatic cystic lesions with malignant potential, such as CNPs, and the possibility of providing early surgical treatment with curative potential.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 190-199"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148007415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Jejunal intussusception secondary to migration of a provisional gastrostomy catheter","authors":"P.M. Juárez-Villa,&nbsp;A.G. Valladares-Pasquel,&nbsp;A. Tepox-Padrón,&nbsp;A. Osorio-Miranda,&nbsp;L.G. Pedroza-Terán","doi":"10.1016/j.rgmxen.2025.09.027","DOIUrl":"10.1016/j.rgmxen.2025.09.027","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 268-270"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent acute pancreatitis associated with Luschka ducts: A diagnostic pathway proposal","authors":"Y. Rivera-Suazo,&nbsp;M.S. Gallardo-Luna,&nbsp;J.E. Alfaro-Bolaños,&nbsp;A.I. Quesada-Tortoriello","doi":"10.1016/j.rgmxen.2025.10.036","DOIUrl":"10.1016/j.rgmxen.2025.10.036","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 272-275"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Duodenal leiomyosarcoma: Presentation of an exceptional diagnosis and complex surgical approach","authors":"O. Dobato-Portoles,&nbsp;M.T. Abadia-Forcen,&nbsp;S. Paterna-López,&nbsp;M. Gutiérrez-Díez,&nbsp;A. Serrablo-Requejo","doi":"10.1016/j.rgmxen.2025.12.004","DOIUrl":"10.1016/j.rgmxen.2025.12.004","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 131-133"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145919275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional results after ventral mesh rectopexy in 50 patients with obstructed defecation and/or fecal incontinence","authors":"A. Rivera-Garcia Granados,&nbsp;M.A. López-Ramírez,&nbsp;F. Urbina-Alatriste,&nbsp;V. Flores-Gamboa","doi":"10.1016/j.rgmxen.2025.12.008","DOIUrl":"10.1016/j.rgmxen.2025.12.008","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Ventral mesh rectopexy (VMR) for correcting rectal prolapse, rectocele, and enterocele improves obstructed defecation syndrome (ODS) and fecal incontinence (FI). This procedure is popular due to its minimally invasive approach and favorable clinical outcomes. Our aim was to evaluate the clinical response of patients that underwent VMR, focusing on changes in the ODS and FI scores.</div></div><div><h3>Material and methods</h3><div>A retrospective, observational, cohort study was conducted on patients that underwent VMR within the time frame of May 2019 and May 2024 at a high-volume hospital. Fifty case records were analyzed, measuring the changes in the scores of the ODS scale and CCF-FIS, before and after surgery. Statistical significance was set at a p &lt; 0.05.</div></div><div><h3>Results</h3><div>The ODS scores decreased from 10.76 to 6.28 and the FI scores from 9 to 5, showing significant improvement. When analyzing individual items of each of the scales separately, all in the ODS scale were statistically significant, whereas in the FI scale, only pad use and impact on social life were significant. There were no major intraoperative complications or conversions to open surgery and the mean hospital stay was1.96 days. No significant differences in outcomes were found between the conventional and robotic laparoscopic approaches.</div></div><div><h3>Conclusions</h3><div>VMR is a safe and effective procedure for improving ODS and FI symptoms in the Mexican population. Long-term follow-up is required to confirm the persistence of benefits and evaluate late complications.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 12-18"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145914110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a machine learning model for predicting right-sided colon cancer recurrence: A retrospective single center pilot study","authors":"R. Zayas-Bórquez,&nbsp;J. Canto-Losa,&nbsp;E. Posadas-Trujillo,&nbsp;N. Salgado-Nesme,&nbsp;O. Santes","doi":"10.1016/j.rgmxen.2025.12.013","DOIUrl":"10.1016/j.rgmxen.2025.12.013","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Right-sided colon cancer (RSCC) is characterized by distinct clinical features and recurrence patterns. Our study aimed to develop a predictive model for distant recurrence in patients with RSCC who underwent curative surgery, employing the Random Forest machine learning algorithm, based on clinical and histopathologic variables.</div></div><div><h3>Materials and methods</h3><div>A retrospective analysis of 64 patients treated within the time frame of 2016–2024 was conducted. The variables included age, sex, lymphovascular invasion, and number of lymph nodes evaluated (transformed for inverse interpretation). Oversampling was employed to balance the dataset and a Random Forest model for predicting distant recurrence (defined as that occurring at least six months after surgery) was constructed. Its performance was evaluated through accuracy, sensitivity, F1 score, and area under the ROC curve (AUC).</div></div><div><h3>Results</h3><div>The model achieved an AUC of 0.76 in the test set, with 75% sensitivity and 100% specificity. The most relevant variables were low lymph node harvest, older age, male sex, and lymphovascular invasion. A simplified model with those four variables maintained 95% accuracy. A clinical risk scale based on cumulative scores was developed that classified patients into low-risk and high-risk groups, with distant recurrence rates of 8.3% and 56.3%, respectively.</div></div><div><h3>Conclusion</h3><div>The predictive model showed a robust capacity for stratifying the distant recurrence risk, supporting the use of machine learning algorithms as a complementary tool in the individualized management of RSCC.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 68-75"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145992135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Fifth Mexican consensus on the diagnosis and treatment of Helicobacter pylori infection","authors":"J.M. Remes-Troche ,&nbsp;F. Bosques-Padilla ,&nbsp;A.D. Cano-Contreras ,&nbsp;J.A. Velarde-Ruiz Velasco ,&nbsp;M.V. Bielsa-Fernández ,&nbsp;M. Camorlinga Ponce ,&nbsp;M.C. Camargo ,&nbsp;E. Coss-Adame ,&nbsp;F. Esquivel-Ayanegui ,&nbsp;A.R. Flores-Rendón ,&nbsp;O. Gómez-Escudero ,&nbsp;M.S. González-Huezo ,&nbsp;F. Higuera-de-la-Tijera ,&nbsp;Y.A. Leal-Herrera ,&nbsp;Y. López-Vidal ,&nbsp;E.C. Morel-Cerda ,&nbsp;A. Noble-Lugo ,&nbsp;N. Xochiquetzal Ortiz-Olvera ,&nbsp;R. Raña-Garibay ,&nbsp;A. Riquelme ,&nbsp;L.R. Valdovinos-García","doi":"10.1016/j.rgmxen.2025.12.001","DOIUrl":"10.1016/j.rgmxen.2025.12.001","url":null,"abstract":"<div><div><em>Helicobacter pylori</em> (<em>H. pylori)</em> infection remains highly prevalent in Mexico and worldwide. In response to the advances in diagnosis, treatment, and epidemiologic surveillance, the <em>Asociación Mexicana de Gastroenterología</em>, through a multidisciplinary panel of experts, developed the “Fifth Mexican Consensus on <em>H. pylori</em>” in 2025, providing 38 evidence-based recommendations tailored to the Mexican context. The document highlights the establishment of the Hp-MexReg national registry and its collaboration with Hp-LatamReg and HpRESLA projects, enabling the collection of local data on eradication rates and antimicrobial resistance. The expert group reaffirms the high prevalence of <em>H. pylori</em> in Mexico (70.5%) related to social and sanitation factors, as well as the increase of antibiotic-resistant strains, particularly to clarithromycin and levofloxacin. Regarding diagnosis, the 13C-urea breath test is prioritized as the first-line noninvasive method and eradication of the bacterium should be confirmed at least four weeks after treatment. Regarding treatment, quadruple therapies, with or without bismuth, are recommended over standard triple therapy, and potassium-competitive acid blockers are endorsed as an effective alternative to high-dose proton pump inhibitors. <em>H. pylori</em> eradication is strongly recommended, with emphasis on the clinical scenarios in which it is indicated. The present consensus underscores the need to continue conducting national studies that enable strategies to be adapted to Mexico’s epidemiologic reality.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 89-114"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145800968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced combination therapy: Janus kinase inhibitors and TNF inhibitors in the treatment of patients with inflammatory bowel disease","authors":"F. Carvajal,&nbsp;P. Núñez,&nbsp;R. Quera,&nbsp;G. Pizarro,&nbsp;L. Flores","doi":"10.1016/j.rgmxen.2025.06.002","DOIUrl":"10.1016/j.rgmxen.2025.06.002","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 128-131"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case series of a novel inflammatory bowel disease phenotype (UC2CD) in Mexican patients","authors":"J.K. Yamamoto-Furusho,&nbsp;F.D. Gutiérrez-Herrera,&nbsp;I.E. Bravo-Espinoza,&nbsp;I.P. Padilla-Betancourt","doi":"10.1016/j.rgmxen.2025.08.003","DOIUrl":"10.1016/j.rgmxen.2025.08.003","url":null,"abstract":"<div><div>A novel inflammatory bowel disease phenotype, named UC2CD, was recently described and is characterized by the transformation from ulcerative colitis (UC) to the Crohn’s disease (CD) phenotype, with distinct clinical, serologic, and genetic features. In our case series, we describe the clinical characteristics of 8 patients presenting with this new phenotype, treated at the Inflammatory Bowel Disease Clinic of the <em>Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán</em> (<em>INCMNSZ</em>).</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 140-143"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147870796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}