R.G. Roncal-Odar, M. Rosenthal-Ojeda, G.C. Fernández
{"title":"Beyond diet: the role of awareness and socioeconomic status in metabolic dysfunction-associated steatotic liver disease","authors":"R.G. Roncal-Odar, M. Rosenthal-Ojeda, G.C. Fernández","doi":"10.1016/j.rgmxen.2025.12.016","DOIUrl":"10.1016/j.rgmxen.2025.12.016","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 295-296"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.L. Herrera-Elizondo, R.A. Jiménez-Castillo, D. García-Compeán, J.O. Jaquez-Quintana, C.A. Cortez-Hernández, C.E. González-Martínez, H.J. Maldonado-Garza, A. Garza-Galindo, J. Campos-Galván, J.A. González-González
{"title":"High-dose metoclopramide versus placebo for gastroduodenal visualization during endoscopy in patients with acute upper gastrointestinal bleeding. A triple-blind, randomized clinical trial","authors":"J.L. Herrera-Elizondo, R.A. Jiménez-Castillo, D. García-Compeán, J.O. Jaquez-Quintana, C.A. Cortez-Hernández, C.E. González-Martínez, H.J. Maldonado-Garza, A. Garza-Galindo, J. Campos-Galván, J.A. González-González","doi":"10.1016/j.rgmxen.2026.05.005","DOIUrl":"10.1016/j.rgmxen.2026.05.005","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>The usefulness of metoclopramide for improving endoscopic visualization in upper gastrointestinal bleeding (UGIB) is controversial. Our primary aim was to evaluate the utility of metoclopramide 20 mg/IV for endoscopic visualization in UGIB of ≤ 24 h. The need for a repeat endoscopy and length of hospital stay were also analyzed.</div></div><div><h3>Materials and methods</h3><div>Patients were randomized 1:1 to receive placebo (group A) or metoclopramide 20 mg/IV (group B) and undergo endoscopy 30−120 min later. Demographics, etiology, and hospital stay were evaluated. The percentage of gastroduodenal visualization was assessed through the modified Avgerinos score. A blinded, experienced endoscopist reviewed the endoscopic recordings.</div></div><div><h3>Results</h3><div>Fifty patients, 27 men and 23 women, were included. Mean patient age was 60 years, and each group was made up of 25 patients. The time from admission to endoscopy in group A was 14:21 h (SD ± 5.35) and 14:54 h (SD ± 5.83) in group B (<em>p</em> = 0.83). The modified Avgerinos score was 7.00 (5.00−8.00) in group A and 7.00 (6.50−8.00) in group B (<em>p</em> = 0.282). The difference in the modified Avgerinos score was not statistically significant in the patients with variceal and ulcerous etiologies (<em>p</em> = 0.705 and <em>p</em> = 0.721, respectively). A repeat endoscopy was required in 3 group A patients and 4 group B patients (<em>p</em> = 0.684). Hospital stay for group A was 7.0 days (SD ± 3.08) and 7.32 days (SD ± 4.31) for group B (<em>p</em> = 0.764).</div></div><div><h3>Conclusions</h3><div>Metoclopramide 20 mg/IV before endoscopy did not improve endoscopic visualization, the need for a repeat endoscopy, or length of hospital stay in patients with UGIB.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 212-220"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148206892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gastrointestinal bleeding and anticoagulation in the Colombian Southwest","authors":"C.A. Rojas-Rodríguez, A.F. Mejía-Hurtado, L.J. Hurtado-Bermúdez, J.C. Ramírez-Márquez, E.D. Salazar-Cardona, M. González-Hurtado, E.E. Rojas-Díaz, Y.C. Cárdenas-Trujillo, J.P. Castro-Piedrahita, C.A. Mejía-Gómez, N.E. Rojas-Rojas, D.A. Pantoja-Castro, J.E. Gómez-Mesa","doi":"10.1016/j.rgmxen.2026.05.003","DOIUrl":"10.1016/j.rgmxen.2026.05.003","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Anticoagulants, essential in the treatment of different cardiovascular conditions, increase the risk of gastrointestinal bleeding. This risk varies, according to the type and administration route of the anticoagulant. National studies report bleeding rates between 0.5% and 4.7%, whereas worldwide rates vary between 4% and 17%. The present study characterizes the anticoagulated population with gastrointestinal bleeding, followed at a referral anticoagulation clinic, contributing to the regional epidemiology and clinical decision-making.</div></div><div><h3>Materials and methods</h3><div>A cross-sectional study was conducted on non-pregnant patients anticoagulated with warfarin, direct-acting oral anticoagulants, or parenteral anticoagulants, and who presented with gastrointestinal bleeding, within the time frame of January 2018 and June 2022.</div></div><div><h3>Results</h3><div>The study included 121 patients. The main indication for anticoagulation was atrial fibrillation (35%) and at least 30% had a previous bleeding episode. The upper gastrointestinal tract was the primary origin of bleeding (51%). There were no statistically significant differences in the therapeutic interventions between the different anticoagulant agents evaluated. A total of 9.1% of patients presented with rebleeding during hospitalization and in-hospital mortality was 2.5%.</div></div><div><h3>Conclusions</h3><div>Our findings showed that patients with gastrointestinal bleeding associated with anticoagulant use had no relevant differences regarding clinical characteristics, treatment regimen, and outcomes, according to the type of anticoagulant employed. The behavior of gastrointestinal bleeding in anticoagulated patients may be similar to that of non-anticoagulated patients. Further studies comparing these two patient groups are warranted.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 179-189"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148007445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.M. Remes-Troche, A. Cano-Contreras, F. Bosques-Padilla
{"title":"Response to Valdovinos-Díaz et al., regarding «Rebamipide as adjuvant therapy in Helicobacter pylori eradication regimens»","authors":"J.M. Remes-Troche, A. Cano-Contreras, F. Bosques-Padilla","doi":"10.1016/j.rgmxen.2026.01.003","DOIUrl":"10.1016/j.rgmxen.2026.01.003","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 287-289"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C.A. González-Heredia, A.Y. Martínez-Vázquez, F.E. Hernández-Lara-González, Y. Martínez Tovilla
{"title":"Risk factors associated with early complications in pediatric patients diagnosed with acute pancreatitis","authors":"C.A. González-Heredia, A.Y. Martínez-Vázquez, F.E. Hernández-Lara-González, Y. Martínez Tovilla","doi":"10.1016/j.rgmxen.2025.08.004","DOIUrl":"10.1016/j.rgmxen.2025.08.004","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Acute pancreatitis is a rare condition in pediatric patients, but there has been a considerable increase in cases and complications in recent years that, according to the literature, may reach up to 30% of cases. The present study aimed to determine whether the variables of sex, age group, etiology, nutritional status, lipase level, albumin level, and leukocyte count were associated with the development of early complications in pediatric patients diagnosed with acute pancreatitis.</div></div><div><h3>Materials and methods</h3><div>A retrospective study was carried out at the <em>Hospital para el Niño Poblano</em>, within the time frame of July 2014 and July 2024. The medical records of patients from 0 to 17 years 11 months of age, who met the diagnostic criteria for acute pancreatitis, were analyzed. JASP software was utilized for the statistical analysis, applying odds ratio (OR) to identify possible risk factors.</div></div><div><h3>Results</h3><div>A total of 143 patients were included, with a slight predominance of females (51%, <em>n</em> = 73). Of the local complications, pancreatic necrosis was documented in 16% (<em>n</em> = 23) and acute peripancreatic fluid collection in 12.6% (<em>n</em> = 18). The most frequent complications were cardiac (51.75%), renal (31.47%), pulmonary (18.18%), and metabolic (16.08%).</div></div><div><h3>Conclusion</h3><div>Significant risk factors for the development of early complications in pediatric patients with acute pancreatitis were identified. These findings may support early assessment of disease severity and guide timely interventions.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 171-178"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148229518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor regarding the article “Metabolic dysfunction-associated steatotic liver disease and dietary intake characteristics in children and adolescents: A cross-sectional study”","authors":"B. Hernández","doi":"10.1016/j.rgmxen.2025.12.017","DOIUrl":"10.1016/j.rgmxen.2025.12.017","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Page 294"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Zayas-Bórquez, C.Z. Diaz-Barrientos, J. Canto-Losa, N. Salgado-Nesme, O. Santes-Jasso
{"title":"What factors prolong symptoms in patients with hemorrhoidal disease who require surgery?","authors":"R. Zayas-Bórquez, C.Z. Diaz-Barrientos, J. Canto-Losa, N. Salgado-Nesme, O. Santes-Jasso","doi":"10.1016/j.rgmxen.2026.05.004","DOIUrl":"10.1016/j.rgmxen.2026.05.004","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Hemorrhoidal disease is a common condition and may affect quality of life. Although it tends to respond to conservative treatment, some cases require surgery. The present study examined clinical and demographic factors associated with symptom duration in surgically treated patients, with no causal inference or predictive intent.</div></div><div><h3>Materials and methods</h3><div>A retrospective, cross-sectional study was conducted at the Hospital Universitario de Puebla on 56 patients who underwent hemorrhoidectomy (2019-2023). The factors of sex, age, smoking, constipation, BMI, and time to surgery were analyzed, employing descriptive statistics, linear regression, and K-Fold cross-validation.</div></div><div><h3>Results</h3><div>There was a significant association between sex and years of disease (p = 0.0427), with men having a mean 4.89 more years of disease than women (β = –4.89, 95% CI –9.61 to –0.17). There was a positive, non-significant association between age and years of disease (p = 0.0907). A significant inverse relation was identified between age at disease onset and years of disease (p < 0.001; β = –0.31, 95% CI –0.46 to –0.15), as well as a significant interaction between sex and age at onset (p < 0.001).</div></div><div><h3>Conclusions</h3><div>Sex and age at disease onset were key factors associated with symptom duration in patients who underwent hemorrhoidectomy. Factors traditionally considered relevant, such as constipation and BMI, showed no significant association, highlighting the importance of considering complex interactions between clinical and demographic variables.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 207-211"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148206941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Chelech, R. Quera, J. Saba, P. Núñez, G. Pizarro
{"title":"Upadacitinib use in a pediatric patient with Crohn’s disease and primary loss of response to adalimumab: A case report","authors":"F. Chelech, R. Quera, J. Saba, P. Núñez, G. Pizarro","doi":"10.1016/j.rgmxen.2025.12.012","DOIUrl":"10.1016/j.rgmxen.2025.12.012","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 263-265"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145985182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Quadros-Santos, H. Pinchemel-Cotrim, C.H. Da Cunha-Daltro, R. Rocha
{"title":"Response to Fernández GC et al., “Beyond diet: the role of awareness and socioeconomic status in metabolic dysfunction-associated steatotic liver disease”","authors":"P. Quadros-Santos, H. Pinchemel-Cotrim, C.H. Da Cunha-Daltro, R. Rocha","doi":"10.1016/j.rgmxen.2026.03.001","DOIUrl":"10.1016/j.rgmxen.2026.03.001","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 296-297"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O.A. Bautista Ley, K.A. Luna Montaño, J.A. Rodríguez Ruíz
{"title":"Duodenal perforation caused by a biliary stentolith: A late sequela of the stone-stent complex","authors":"O.A. Bautista Ley, K.A. Luna Montaño, J.A. Rodríguez Ruíz","doi":"10.1016/j.rgmxen.2026.05.007","DOIUrl":"10.1016/j.rgmxen.2026.05.007","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 254-257"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}