Good clinical practice recommendations for the management of gastroesophageal reflux disease. A Latin American expert review

Revista de gastroenterologia de Mexico (English) Pub Date : 2025-04-01 DOI:10.1016/j.rgmxen.2025.02.001

M.A. Valdovinos-Díaz , A. Hani , C. Defilippi-Guerra , L. Fernando-Pineda , J.M. Remes-Troche , A. Riquelme , L.J. Abrahão-Junior , L. Aguilar-Paiz , C. Almonte-Nuñez , H. Burgos , C. Días , O. Gómez-Escudero , I. Hanna-Jairala , C. Olano , J.A. Olmos , A. Ortiz , G. Otoya , J.L. Tamayo-de la Cuesta , J. Suazo-Barahona , E. Vesco-Monteagudo , J.S. Arenas-Martínez

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Abstract

Introduction and aim

Due to its elevated prevalence, complex pathophysiology, and broad spectrum of clinical manifestations, gastroesophageal reflux disease (GERD) requires precision diagnosis and treatment. The aim of this Latin American expert review was to provide good clinical practice recommendations for the rational use of diagnostic tests and the personalized treatment of GERD.

Methods

Good clinical practice recommendations were developed by a group of Latin American experts in GERD. A thorough review of the literature was conducted, and recommendations on the diagnosis and treatment of GERD were issued after three group discussions.

Results

Twenty-one experts on GERD formulated 30 clinical recommendations for appropriately indicating diagnostic tests for disease phenotypes and their medical treatment, refractory GERD management, endoscopic and surgical treatment indications, the control of GERD in obesity, pregnancy, and older adults, as well as the role of Helicobacter pylori infection and GLP-1 agonists.

Conclusions

Determining GERD phenotypes in patients through the appropriate use of diagnostic tests enables personalized treatment to be prescribed. The recommendations established in this document may contribute to improving the quality of care of patients with GERD.

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胃食管反流病管理的良好临床规范建议。拉丁美洲专家审查。

前言与目的：胃食管反流病（GERD）发病率高，病理生理复杂，临床表现广谱，需要精确的诊断和治疗。这项拉丁美洲专家审查的目的是为合理使用诊断测试和个性化治疗反流胃食管反流提供良好的临床实践建议。方法：一组拉丁美洲的反流胃食管反流专家提出了良好的临床实践建议。我们对文献进行了全面的回顾，并在三次小组讨论后提出了关于胃食管反流的诊断和治疗的建议。结果：21位GERD专家制定了30项临床建议，包括疾病表型诊断检查及其药物治疗，难治性GERD管理，内镜和手术治疗指征，肥胖、妊娠和老年人GERD的控制，以及幽门螺杆菌感染和GLP-1激动剂的作用。结论：通过适当使用诊断测试来确定患者的GERD表型，可以制定个性化的治疗方案。本文件中建立的建议可能有助于提高胃食管反流患者的护理质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista de gastroenterologia de Mexico (English)

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审稿时长

12 weeks