Revista de gastroenterologia de Mexico (English)最新文献

Esophagogastric junction outflow obstruction: advances in diagnosis and clinical management. 食管胃交界流出梗阻：诊断与临床治疗进展。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-17 DOI: 10.1016/j.rgmxen.2026.03.005

J S Arenas-Martinez, M F Vela

{"title":"Esophagogastric junction outflow obstruction: advances in diagnosis and clinical management.","authors":"J S Arenas-Martinez, M F Vela","doi":"10.1016/j.rgmxen.2026.03.005","DOIUrl":"https://doi.org/10.1016/j.rgmxen.2026.03.005","url":null,"abstract":"Esophagogastric junction outflow obstruction (EGJOO) is an esophageal motility disorder characterized by incomplete lower esophageal sphincter relaxation, with at least partially preserved peristalsis. Recognition of this entity has evolved with the Chicago Classification version 4.0, which has refined diagnostic criteria by incorporating clinical correlation and confirmatory testing, thereby reducing the overdiagnosis observed with previous versions. Diagnosis is based on high-resolution esophageal manometry, identifying elevated integrated relaxation pressure of the lower esophageal sphincter in both supine and upright positions, as well as intrabolus pressurization. However, those findings may lack clinical relevance, prompting the performance of complementary studies, such as timed barium esophagram, functional lumen imaging probe, and provocative maneuvers during manometry, to confirm clinically significant obstruction. Therapeutic options include pharmacologic therapy, botulinum toxin type A injection, pneumatic dilation, peroral endoscopic myotomy, and surgical myotomy, with growing evidence supporting lower esophageal sphincter-targeted interventions in patients with confirmed obstruction. Additionally, opioid use is an important modifying factor, influencing both motor phenotype and therapeutic response. The current understanding of EGJOO highlights the need for a multimodal diagnostic approach and personalized therapeutic strategies. Nevertheless, there are still important gaps regarding the prediction of clinical progression and the standardization of emerging diagnostic tools.","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149217550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse large B-cell lymphoma of the colon: surgical complexities in a rare tumor. 结肠弥漫性大b细胞淋巴瘤：一例罕见肿瘤的手术复杂性。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-14 DOI: 10.1016/j.rgmxen.2026.01.004

K J Fuentes-Calvo, M F Ramos-Griera, D Doniz Gómez-Llanos, F Aguilar-Ruiz, O Vergara-Fernández

引用次数: 0

Chronic diarrhea as a manifestation of exocrine pancreatic insufficiency associated with pancreatic cystic lesions. 慢性腹泻是外分泌胰腺功能不全与胰腺囊性病变相关的一种表现。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-14 DOI: 10.1016/j.rgmxen.2026.10.001

Al Tornel Avelar, C Zacapantzi Carrillo, R Palos Cuellar

引用次数: 0

Liver injury induced by a kombucha-based nutritional supplement: A case report. 以康布菌为基础的营养补充剂引起的肝损伤1例报告。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-14 DOI: 10.1016/j.rgmxen.2025.11.003

D A Belmontes-Gutiérrez, P A Moreno-Velazco, L I Gurza-Morales

引用次数: 0

Intractable hiccups as initial manifestation of achalasia: a case report. 顽固性呃逆是贲门失弛缓症的最初表现：1例报告。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-14 DOI: 10.1016/j.rgmxen.2026.03.004

C I Zubia-Nevárez, M Herrera-Sato, J S Arenas-Martínez, D I Carmona-Guerrero, G M Torres-Villalobos, E Coss-Adame

{"title":"Intractable hiccups as initial manifestation of achalasia: a case report.","authors":"C I Zubia-Nevárez, M Herrera-Sato, J S Arenas-Martínez, D I Carmona-Guerrero, G M Torres-Villalobos, E Coss-Adame","doi":"10.1016/j.rgmxen.2026.03.004","DOIUrl":"https://doi.org/10.1016/j.rgmxen.2026.03.004","url":null,"abstract":"Background: Intractable hiccups pose a clinical challenge due to their diverse etiologies and lack of standard treatment. While associated with esophageal conditions, hiccups rarely occur in achalasia.Case report: A 65-year-old man presented with intractable hiccups, heartburn, and regurgitation for 7 years and progressive dysphagia and weight loss for 2 years. He was unrelieved by Nissen fundoplication for suspected gastroesophageal reflux disease (GERD), performed with no previous assessment of esophageal motility. Two years later, high-resolution impedance manometry (HRIM) revealed type I achalasia. The patient underwent a Heller myotomy, with revision of the fundoplication, resulting in complete resolution of dysphagia, regurgitation, and hiccups.Conclusion: This case underscores the rare association of hiccups with achalasia, as well as the importance of manometric assessment in cases of atypical symptoms and dysphagia, and the efficacy of surgical intervention in refractory cases.","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary biliary cholangitis in Mexico: an emerging reality in the era of new therapies. 墨西哥原发性胆道炎：新疗法时代的新现实。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-14 DOI: 10.1016/j.rgmxen.2026.03.003

I García-Juárez, O S Pineda-Arzate, L Toapanta-Yanchapaxi, S Muñoz-Martínez

引用次数: 0

Prevalence and clinical characteristics of colorectal adenocarcinoma in young adults in Mexico: A systematic review and meta-analysis. 墨西哥年轻人结直肠癌的患病率和临床特征：一项系统综述和荟萃分析。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-14 DOI: 10.1016/j.rgmxen.2025.12.018

D Arriaga-Izabal, F Morales-Lazcano, U A Angulo-Zamudio, A Canizalez-Román, N León-Sicairos

{"title":"Prevalence and clinical characteristics of colorectal adenocarcinoma in young adults in Mexico: A systematic review and meta-analysis.","authors":"D Arriaga-Izabal, F Morales-Lazcano, U A Angulo-Zamudio, A Canizalez-Román, N León-Sicairos","doi":"10.1016/j.rgmxen.2025.12.018","DOIUrl":"https://doi.org/10.1016/j.rgmxen.2025.12.018","url":null,"abstract":"Introduction and aims: The prevalence of colorectal cancer in young adults is increasing worldwide but there is limited data from Latin American countries. In Mexico, the burden and clinical profile of colorectal adenocarcinoma in young patients are not well characterized. Our study aimed to estimate the prevalence of colorectal adenocarcinoma and describe its clinical characteristics, in young adult patients in Mexico.Materials and methods: The PubMed and Web of Science databases were systematically searched from database inception to September 2024. The prevalence of colorectal adenocarcinoma in young adults in Mexico was evaluated, comparing the clinical characteristics of early-onset and late-onset cases. A pooled meta-analysis was carried out, using random effects models. Heterogeneity was assessed through the I² statistic, meta-regression, and subgroup analyses. The risk of bias was evaluated using the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data.Results: The pooled prevalence of colorectal adenocarcinoma in young adults was 10% (95% CI 6-15 %) in patients ≤40 years of age and 19% (95% CI 18-21 %) in those under 50 years of age. Meta-regression indicated a growing trend in the under 40 age group over time and the predominating clinical factors were male sex (52%), rectal involvement (44%), stage IV disease at diagnosis (32%), and a greater number of poorly differentiated tumors.Conclusion: Colorectal adenocarcinoma in young adults is an emerging public health concern in Mexico that requires specific strategies targeting prevention and early detection.","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastroenteropancreatic neuroendocrine neoplasms: A 20-year experience at a tertiary care medical center in Mexico City. 胃肠胰神经内分泌肿瘤：在墨西哥城三级医疗中心的20年经验。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-14 DOI: 10.1016/j.rgmxen.2026.09.008

S Wuotto-Alvarado, R Gerson-Cwilich, A Noguez-Ramos

{"title":"Gastroenteropancreatic neuroendocrine neoplasms: A 20-year experience at a tertiary care medical center in Mexico City.","authors":"S Wuotto-Alvarado, R Gerson-Cwilich, A Noguez-Ramos","doi":"10.1016/j.rgmxen.2026.09.008","DOIUrl":"https://doi.org/10.1016/j.rgmxen.2026.09.008","url":null,"abstract":"Introduction and aims: Neuroendocrine neoplasms are a heterogeneous group of tumors, primarily located in the gastroenteropancreatic system. In Mexico, clinical and epidemiologic data on them are limited. Our aim was to describe the experience with gastroenteropancreatic neuroendocrine neoplasms at a tertiary care medical center and analyze the factors associated with survival.Materials and methods: A retrospective analytic cohort study was conducted.Results: The study included 110 patients with a mean age of 58 years (SD ± 13.8), 55.5% of whom were women. The pancreas was the most common primary site (50%). Functional tumors accounted for 28.2% of cases and carcinoid syndrome for 9.1%. Performance status was preserved in 96.3% of patients (ECOG 0-1). At diagnosis, 50% presented with advanced disease, of whom 61.3% had high hepatic tumor burden. The median follow-up period was 37.5 months. Overall survival (OS) was 162 months (SD ± 12.8). The factors associated with better OS were preserved performance status (p < 0.001), CgA ≤ 700 ng/mL (p = 0.02), Ki-67 < 5% (p = 0.03), and low hepatic tumor burden (p = 0.02). The factors associated with better progression-free survival were preserved performance status (p = 0.022), histologic grade (p = 0.02), CgA ≤ 700 ng/mL (p = 0.03), and objective response rate (p < 0.001).Conclusions: At our medical center, the most frequent primary site was the pancreas and most of the patients were women, differing from international reports. Factors associated with better survival were identified, including preserved performance status, CgA ≤ 700 ng/mL, histologic grade, Ki-67 < 5%, low hepatic tumor burden, and objective response rate.","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extramedullary plasmacytoma or plasmablastic lymphoma? On the role of Ki-67 in the assessment of light chain restriction. 髓外浆细胞瘤还是浆母细胞淋巴瘤？Ki-67在轻链限制评价中的作用。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-14 DOI: 10.1016/j.rgmxen.2026.02.005

J A Teco Cortes

引用次数: 0

Transnasal endoscopy as a complementary tool for ambulatory detection of clinically significant portal hypertension. 经鼻内窥镜作为一种辅助工具，为门诊检测临床显著门静脉高压症。

Revista de gastroenterologia de Mexico (English) Pub Date : 2026-10-14 DOI: 10.1016/j.rgmxen.2026.10.002

C A Cortez-Hernández, L A González-Torres, R A Jiménez-Castillo, J A González-González, J M Millan-Alanis, C E González-Martínez, M A Saldaña-Ruiz, J A Cortez-Castilleja, N Rodríguez-Ávila, Y Ríos-Feria, H J Maldonado-Garza

{"title":"Transnasal endoscopy as a complementary tool for ambulatory detection of clinically significant portal hypertension.","authors":"C A Cortez-Hernández, L A González-Torres, R A Jiménez-Castillo, J A González-González, J M Millan-Alanis, C E González-Martínez, M A Saldaña-Ruiz, J A Cortez-Castilleja, N Rodríguez-Ávila, Y Ríos-Feria, H J Maldonado-Garza","doi":"10.1016/j.rgmxen.2026.10.002","DOIUrl":"https://doi.org/10.1016/j.rgmxen.2026.10.002","url":null,"abstract":"The efficacy, safety, and tolerability of transnasal endoscopy were evaluated as a complementary tool for detecting endoscopic signs consistent with portal hypertension in adults with compensated advanced chronic liver disease. Twenty-four patients underwent transnasal upper gastrointestinal endoscopy under local anesthesia and noninvasive assessment of liver fibrosis through elastography and platelet count. Procedure-related pain intensity and anxiety, adverse events, and impact on therapeutic decision-making were analyzed. The procedure was well tolerated, with no adverse events, and periprocedural discomfort and anxiety were minimal-to-mild. Transnasal endoscopy modified therapeutic decisions in 37.5% of cases, compared with the exclusive use of noninvasive methods. The findings suggest that transnasal endoscopy may provide additional value for the ambulatory detection of portal hypertension, as it is a rapid and practical procedure.","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149186793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0