{"title":"Endoscopic findings of rectal cryptococcosis in an HIV patient: A case report","authors":"J.E. Méndez-Benítez, C.A. Ramos-Matamoros, J.O. Jáquez-Quintana","doi":"10.1016/j.rgmxen.2025.09.029","DOIUrl":"10.1016/j.rgmxen.2025.09.029","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 270-272"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Cordova-Gallardo, A.M. Vargas-Beltrán, L.A. Bastida-Castro, A. Gamboa-Domínguez, A. Gabutti-Thomas, D. Valla
{"title":"Correlation of clinical and pathologic characteristics in Mexican patients with porto-sinusoidal vascular disease","authors":"J. Cordova-Gallardo, A.M. Vargas-Beltrán, L.A. Bastida-Castro, A. Gamboa-Domínguez, A. Gabutti-Thomas, D. Valla","doi":"10.1016/j.rgmxen.2026.06.002","DOIUrl":"10.1016/j.rgmxen.2026.06.002","url":null,"abstract":"<div><div>Porto-sinusoidal vascular disease (PSVD) is an uncommon disorder characterized by hepatic microvascular alterations and noncirrhotic portal hypertension. Its recent redefinition includes patients with and without portal hypertension, even in the presence of concomitant liver disease. The present study aimed to correlate the clinical, radiologic, and histopathologic findings in Mexican patients with PSVD and identify key diagnostic challenges.</div><div>A retrospective study was conducted on ten patients diagnosed with PSVD according to updated criteria, in whom liver biopsy showed no cirrhosis. Clinical, laboratory, imaging, and histopathologic data were collected. Upper gastrointestinal bleeding was the most frequent initial presentation, followed by mild thrombocytopenia. Biopsies revealed obliterative portal venopathy, nodular regenerative hyperplasia, and incomplete septal fibrosis. Magnetic resonance imaging identified periportal hyperintensity, which aided in differentiating PSVD from cirrhosis.</div><div>The findings confirm PSVD heterogeneity, underscoring the importance of integrating different diagnostic tools for its timely detection.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 276-281"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148240652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Cembellin-Prieto, D. Fernández-Martínez, L.J. García-Flórez
{"title":"Cardiac pacemaker migrated to the colon","authors":"A. Cembellin-Prieto, D. Fernández-Martínez, L.J. García-Flórez","doi":"10.1016/j.rgmxen.2026.05.006","DOIUrl":"10.1016/j.rgmxen.2026.05.006","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 258-259"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Splenic hemangioendothelioma in a menopausal woman","authors":"G.S.A. Alegre-Salles, V.J. Alegre-Salles","doi":"10.1016/j.rgmxen.2026.01.002","DOIUrl":"10.1016/j.rgmxen.2026.01.002","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 260-261"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S.A. Chávez-Sánchez, A. Bellido-Caparó, C.A. García-Encinas, P.M. Padilla-Machaca
{"title":"Hepatic involvement as the initial manifestation of B-cell acute lymphoblastic leukemia in adults: A case series","authors":"S.A. Chávez-Sánchez, A. Bellido-Caparó, C.A. García-Encinas, P.M. Padilla-Machaca","doi":"10.1016/j.rgmxen.2026.06.003","DOIUrl":"10.1016/j.rgmxen.2026.06.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Hepatic involvement as an initial presentation of acute lymphoblastic leukemia (ALL) in adults is rare and may delay the diagnosis.</div></div><div><h3>Material and methods</h3><div>A case series of adult patients with confirmed B-cell ALL (B-ALL) and altered liver function tests at disease onset was conducted. Clinical, biochemical, imaging, and flow cytometry data were collected, ruling out infectious, autoimmune, and toxic etiologies.</div></div><div><h3>Results</h3><div>Three men, 68, 36, and 38 years of age, presented with cholestasis and hepatosplenomegaly with no biliary tract dilation. Flow cytometry showed high percentages of B lymphoblasts. One patient died shortly after starting chemotherapy and the other two remain on active treatment.</div></div><div><h3>Conclusion</h3><div>Hepatic infiltration due to ALL should be considered in the differential diagnosis of cholestasis with a normal biliary tract in adults.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 282-285"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to the Letter to the Editor from Teco-Cortes, “UC2CD, a hasty, non-specific term for a questionable entity”","authors":"J.K. Yamamoto-Furusho","doi":"10.1016/j.rgmxen.2026.02.001","DOIUrl":"10.1016/j.rgmxen.2026.02.001","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 290-291"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Hernández-Rosiles, A. Carias-Domínguez, G. Baules de Arrocha, J.F. Garcés-Camacho, M. Fisberg, M.C. Bages-Mesa, M. Higuera-Carillo, W. Daza-Carreño, J. Ho, M. Alfaro-Hurtado, C.L. Taquez-Castro, V. Silva-Weffort, M.S. Peredo, S. Peña-Hernández, M.C. Sanabria, L. Escobedo-Berumen, L. Ladino, S. Sanjuanelo-Camargo, A.M. Pazmiño, A. Zambrano-Rivas, R. Vázquez-Frias
{"title":"Feeding difficulties in childhood: A narrative review and proposal for an interdisciplinary approach","authors":"V. Hernández-Rosiles, A. Carias-Domínguez, G. Baules de Arrocha, J.F. Garcés-Camacho, M. Fisberg, M.C. Bages-Mesa, M. Higuera-Carillo, W. Daza-Carreño, J. Ho, M. Alfaro-Hurtado, C.L. Taquez-Castro, V. Silva-Weffort, M.S. Peredo, S. Peña-Hernández, M.C. Sanabria, L. Escobedo-Berumen, L. Ladino, S. Sanjuanelo-Camargo, A.M. Pazmiño, A. Zambrano-Rivas, R. Vázquez-Frias","doi":"10.1016/j.rgmxen.2026.06.001","DOIUrl":"10.1016/j.rgmxen.2026.06.001","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Feeding difficulties (FDs) in childhood are highly prevalent and a common reason for medical consultation. Historically, clinical approaches have been fragmented. The Pediatric Feeding Disorder (PFD) model provides a comprehensive framework that incorporates medical, nutritional, feeding skill, and psychosocial dimensions. Our aims were to (1) describe the current definitions of FDs in children, (2) identify their main risk factors and existing classifications, and (3) propose a clinical algorithm to guide the diagnostic and therapeutic approach from an interdisciplinary perspective.</div></div><div><h3>Materials and methods</h3><div>A narrative review was carried out by the Feeding Difficulties Working Group of the Latin American Society of Pediatric Gastroenterology, Hepatology and Nutrition (LASPGHAN), reviewing the literature published between January 2000 and April 2025 from the PubMed, Scopus, SciELO, and LILACS databases.</div></div><div><h3>Results</h3><div>Three classification systems were identified: sensory-based, medical/nutritional, and functional. Risk factors included prematurity, gastrointestinal and neuromotor diseases, negative feeding experiences, inadequate feeding practices, and psychosocial factors. A comprehensive and interdisciplinary clinical algorithm was developed.</div></div><div><h3>Conclusions</h3><div>Pediatric FDs require an interdisciplinary and family-centered approach, adapted to the Latin American context. Terminology standardization and clinical criteria harmonization are key steps for optimizing diagnosis, treatment, and research in the region. The development of a clinical algorithm outlining their approach is a first step toward this goal.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 221-230"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.M. Remes-Troche, M. Amieva-Balmori, L.F. Uscanga-Domínguez, E. Coss-Adame, R. Bernal-Reyes, R. Carmona-Sánchez, M.R. Francisco, K.R. García-Zermeño, P.C. Gómez-Castaños, O. Gómez-Escudero, M.F. Huerta de la Torre, M.E. Icaza-Chávez, S.E. Martínez-Vázquez, M.P. Milke-García, E. Montijo-Barrios, C.A. Sánchez-Ramírez, E. Toro-Monjaraz, M.A. Valdovinos-Díaz
{"title":"Clinical guideline of the Asociación Mexicana de Gastroenterología for the diagnosis and treatment of lactose ingestion-related disorders","authors":"J.M. Remes-Troche, M. Amieva-Balmori, L.F. Uscanga-Domínguez, E. Coss-Adame, R. Bernal-Reyes, R. Carmona-Sánchez, M.R. Francisco, K.R. García-Zermeño, P.C. Gómez-Castaños, O. Gómez-Escudero, M.F. Huerta de la Torre, M.E. Icaza-Chávez, S.E. Martínez-Vázquez, M.P. Milke-García, E. Montijo-Barrios, C.A. Sánchez-Ramírez, E. Toro-Monjaraz, M.A. Valdovinos-Díaz","doi":"10.1016/j.rgmxen.2026.02.002","DOIUrl":"10.1016/j.rgmxen.2026.02.002","url":null,"abstract":"<div><div>The aim of the present Clinical Guideline of the <em>Asociación Mexicana de Gastroenterología</em> was to establish clear, updated, evidence-based recommendations for the diagnosis and treatment of lactose ingestion-related disorders (LIRDs), to improve diagnostic accuracy and promote effective, patient-centered clinical management. The methodology employed consisted of a Delphi process coordinated by three experts, with the participation of 15 Mexican specialists (gastroenterologists, pediatricians, and nutritionists). Three working groups (epidemiology/definitions, diagnosis, and treatment) were formed that thoroughly reviewed the medical literature published between 2010 and 2025. A total of 26 statements were formulated. The main results included the precise definition of the different LIRD phenotypes (lactase nonpersistence, hypolactasia, clinical lactose intolerance, self-perceived lactose intolerance, and lactose sensitivity); diagnostic test standardization, highlighting the lactose breath test as a highly sensitive noninvasive tool, complemented by genetic studies and biochemical tests; and the recommendation of personalized treatments ranging from the selective reduction of dietary lactose to the use of exogenous enzymes (lactase) and fermented dairy products. Likewise, the importance of avoiding unnecessary dietary restrictions that could compromise calcium and vitamin D intake was emphasized. Altogether, the present consensus provides a comprehensive framework to optimize the clinical care of patients with LIRDs in Mexico.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 231-253"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148274358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Fernández-Ramírez, D. Aguirre-Villarreal, G. Rosales-Sotomayor, J.J. Andrade-Rojas, M. Lara-Salazar, E. Kauffman-Ortega, A. Ángeles-Ángeles, P. Rodríguez-García, L. Uscanga-Domínguez
{"title":"Predictive capacity of anti-tissue-transglutaminase IgA antibodies to identify intestinal villous atrophy in persons with celiac disease. An observational study at a referral center in Mexico City","authors":"A. Fernández-Ramírez, D. Aguirre-Villarreal, G. Rosales-Sotomayor, J.J. Andrade-Rojas, M. Lara-Salazar, E. Kauffman-Ortega, A. Ángeles-Ángeles, P. Rodríguez-García, L. Uscanga-Domínguez","doi":"10.1016/j.rgmxen.2025.07.002","DOIUrl":"10.1016/j.rgmxen.2025.07.002","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Celiac disease (CD) is an autoimmune enteropathy secondary to gluten exposure, diagnosed through serology and duodenal biopsy. The predictive role of anti-tissue-transglutaminase antibody (aTG IgA) levels ≥ 10 times the upper limit of normal (ULN) in the degree of villous atrophy in duodenal biopsies in patients with CD has recently been evaluated. Our aim was to determine the predictive capacity of aTG IgA levels ≥ 10 times the ULN for detecting intestinal villous atrophy (IVA) in patients with CD.</div></div><div><h3>Materials and methods</h3><div>A retrospective, observational study was conducted on patients with suspected CD who underwent endoscopy with duodenal biopsy at a referral center in Mexico City. Demographic, clinical, and final diagnosis variables were registered. Descriptive statistics and an ROC analysis were performed, evaluating different cutoff points of aTG IgA antibodies as IVA predictors.</div></div><div><h3>Results</h3><div>The study included 366 patients (median age of 51 years). CD was diagnosed in 53 of the cases (14.5%). A total of 107 cases were classified as Marsh 3a-3c, and their main diagnoses were CD (45.8%), small intestinal bacterial overgrowth (23.4%), and tropical sprue (16.8%). The specificity of levels ≥ 10 times the ULN was 100% for Marsh 3a-3c, with 17.9% sensitivity, 74.7% NPV, and 100% PPV. The AUC was 70%, with an optimum threshold ≥ 3.3 U/mL ULN (45.3% sensitivity, 89.2% specificity).</div></div><div><h3>Conclusion</h3><div>Levels of aTG IgA ≥ 10 times the ULN are highly specific but have low sensitivity for predicting IVA in Mexican patients with CD, whereas using levels ≥ 3 times the ULN improves sensitivity, without compromising specificity.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 2","pages":"Pages 155-162"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}