{"title":"Elevated fecal calprotectin: Does capsule endoscopy have a role in the diagnostic algorithm?","authors":"S. Vibhishanan , P. Oka , S. Zammit , R. Sidhu","doi":"10.1016/j.rgmxen.2024.06.006","DOIUrl":"10.1016/j.rgmxen.2024.06.006","url":null,"abstract":"<div><h3>Introduction</h3><div>The purpose of this study was to examine the utility of small bowel capsule endoscopy (SBCE) in the diagnostic pathway of patients that had elevated fecal calprotectin (FC) and normal colonoscopy.</div></div><div><h3>Methods</h3><div>Patients with elevated FC and normal colonoscopy that underwent SBCE in the last 4 years were included. Patients were divided into 3 groups: group 1: patients with isolated small bowel Crohn’s disease (SBCD) on SBCE; group 2: patients with elevated FC but normal SBCE; and group 3: patients with isolated terminal ileitis.</div></div><div><h3>Results</h3><div>The study included 320 patients (group 1: 254 patients, group 2: 50 patients, and group 3: 16 patients). The median age was 42.5 years (IQR 26) across the three groups and 52.4% of the patients had a new diagnosis of SBCD. In group 1, active disease was identified distally in 247 patients (77.2%), proximal involvement in 90 patients (28.1%), and extensive SBCD in 68 patients (21.3%). Magnetic resonance enterography (MRE) was carried out in 229 (90.1%) patients in group 1 and was negative in 42 patients with SBCD. The diagnostic yield of SBCE was higher than that of MRE (p < 0.0001). In group 2, the final diagnoses included <em>Helicobacter pylori</em> infection (n = 2), NSAID use (n = 3), celiac disease (n = 2), and microscopic colitis (n = 1). The final diagnoses in group 3 were idiopathic terminal ileitis (n = 11), inflammatory bowel disease (n = 3), and infective terminal ileitis (n = 2).</div></div><div><h3>Conclusion</h3><div>SBCE influences the patient pathway even when negative/normal. It is better at identifying early SBCD, when compared with MRE.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 1","pages":"Pages 29-35"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to Gómez-Calero et al. concerning their comments on the article “Prevalence and characteristics of gastroesophageal reflux disease in pregnant women”","authors":"M.N. Luu , D.T. Quach","doi":"10.1016/j.rgmxen.2024.09.008","DOIUrl":"10.1016/j.rgmxen.2024.09.008","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 1","pages":"Pages 160-161"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E.A. Montemayor-Garza , L. Santoyo-Fexas , M.I. Wah-Suárez , L.A. González-Torres , R.A. López-Pérez , S. Ramírez-Peña
{"title":"Acute small bowel obstruction caused by a hemobezoar in a peptic ulcer case","authors":"E.A. Montemayor-Garza , L. Santoyo-Fexas , M.I. Wah-Suárez , L.A. González-Torres , R.A. López-Pérez , S. Ramírez-Peña","doi":"10.1016/j.rgmxen.2024.09.006","DOIUrl":"10.1016/j.rgmxen.2024.09.006","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 1","pages":"Pages 151-153"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of conservative treatment in esophageal perforation caused by the ingestion of a blister pack: A case report and literature review","authors":"J.P. Pérez-Macías , M.E. Ramírez-Solís , A.Y. Ortega-Caballero , A.I. Hernández-Guerrero , E.F. Marquez-Bornio","doi":"10.1016/j.rgmxen.2024.11.001","DOIUrl":"10.1016/j.rgmxen.2024.11.001","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 1","pages":"Pages 148-151"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142775270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. von Muhlenbrock , P. Núñez , R. Quera , J. Venegas , N. Pacheco , K. Herrera , F. Castro
{"title":"Clinical description of adults with eosinophilic esophagitis treated at a Chilean university center","authors":"C. von Muhlenbrock , P. Núñez , R. Quera , J. Venegas , N. Pacheco , K. Herrera , F. Castro","doi":"10.1016/j.rgmxen.2024.04.010","DOIUrl":"10.1016/j.rgmxen.2024.04.010","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory disease that affects the esophagus. Its epidemiology in Chile and Latin America is unknown due to the absence of population studies. Our aim was to describe the clinical, endoscopic, and histologic characteristics of adult patients diagnosed with EoE, as well as their treatment response.</div></div><div><h3>Material and methods</h3><div>A descriptive prospective study was conducted on a cohort of patients ≥ 18 years of age with an eosinophil count greater than 15 eosinophils/high power field.</div></div><div><h3>Results</h3><div>A total of 62 patients were included, 75.8% of whom were men. Mean patient age was 38 years, mean age at diagnosis was 34 years, and diagnosis was made later in men. Sixty-five percent had a concomitant immunoallergic disease, and allergic rhinitis was the most frequent. Dysphagia was the most frequent referral, with a predominance of men. Women presented more often with food allergies and peripheral eosinophilia. The most frequent endoscopic finding was edema, followed by rings, with a mean eosinophilic esophagitis endoscopic reference score (EREFS) of 3.5 and a mean eosinophil count in biopsies of 37.5 eosinophils/high power field. Men presented with a higher EREFS and eosinophil count at diagnosis. All patients received treatment and the most frequent was with proton pump inhibitors, followed by combination treatment with corticosteroids. Endoscopic (partial/total) and histologic response rates were 93.5 and 77%, respectively.</div></div><div><h3>Conclusion</h3><div>We found characteristics in our cohort similar to those described in international groups. Women presented with greater autoimmune comorbidity, peripheral eosinophilia, and food allergies, but had a lower eosinophil count and endoscopic score. We found no differences between the different therapeutic regimens.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 1","pages":"Pages 8-14"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tradition and advancement: 90 years of excellence of the Asociación Mexicana de Gastroenterología","authors":"J.M. Remes-Troche","doi":"10.1016/j.rgmxen.2025.01.001","DOIUrl":"10.1016/j.rgmxen.2025.01.001","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 1","pages":"Pages 1-3"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143911818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of small intestinal bacterial overgrowth in Chilean patients with irritable bowel syndrome: A prospective and comparative study","authors":"C. von Muhlenbrock , G. Landskron , A.M. Madrid","doi":"10.1016/j.rgmxen.2024.08.003","DOIUrl":"10.1016/j.rgmxen.2024.08.003","url":null,"abstract":"<div><h3>Introduction and aim</h3><div>Patients with disorders of the gut-brain axis, such as irritable bowel syndrome (IBS), often exhibit small intestinal bacterial overgrowth (SIBO). Its treatment includes rifaximin (RF), ciprofloxacin (CF), neomycin, sulfamethoxazole-trimethoprim, and metronidazole (MZ). RF is a non-absorbable antibiotic, postulated to have fewer adverse effects. Our aim was to assess symptomatic response and SIBO eradication in patients with IBS, using three antibiotic regimens.</div></div><div><h3>Methods</h3><div>A prospective, randomized, double-blind study was conducted on IBS patients over 18 years of age, utilizing the Rome IV questionnaire and lactulose breath test. Those diagnosed with SIBO were randomly assigned to receive antibiotic treatment. Group A was treated with RF, group B with CF, and group C with MZ, each for 10 days. Treatment response was evaluated based on the SIBO eradication rate 15 days after completing therapy, utilizing hydrogen and methane breath tests with lactulose. Self-reported symptoms were recorded on a 10-point Likert scale before, during, and after treatment.</div></div><div><h3>Results</h3><div>Ninety-seven patients with IBS and SIBO were included, 81% of whom completed treatment. Fifty-nine percent of the patients treated with RF achieved SIBO eradication, compared with 53% and 79% of those treated with CR and MZ, respectively. Metronidazole reduced more methane levels, compared with the other groups. However, the greatest reduction in abdominal pain and bloating was observed in the RF group, with a lower percentage of adverse events.</div></div><div><h3>Conclusions</h3><div>Patients with IBS and SIBO benefit from antibiotic therapy. MZ exhibited the best SIBO eradication rate, but RF demonstrated greater symptomatic improvement and a lower rate of adverse effects.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 1","pages":"Pages 54-62"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transitioning from NAFLD to MAFLD to MASLD in the Mexican population","authors":"B.A. Priego-Parra , R. Bernal-Reyes , M.E. Icaza-Chávez , S.E. Martínez-Vázquez , J.M. Remes-Troche","doi":"10.1016/j.rgmxen.2024.09.007","DOIUrl":"10.1016/j.rgmxen.2024.09.007","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 1","pages":"Pages 153-156"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}