J.A. Castrillón-Lozano , R.L. Arroyave-Zuluaga , J.M. Restrepo-Jaller
{"title":"Comparison of the predictive capacity of the Alvarado and AIR scores in the diagnosis of acute appendicitis: A recurrent analysis of already established results?","authors":"J.A. Castrillón-Lozano , R.L. Arroyave-Zuluaga , J.M. Restrepo-Jaller","doi":"10.1016/j.rgmxen.2025.09.026","DOIUrl":"10.1016/j.rgmxen.2025.09.026","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Page 151"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147936247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital glucose-galactose malabsorption: An unusual cause of chronic diarrhea in infancy","authors":"C.A. Cuadros-Mendoza , M.S. Duarte-Moreno , L.V. Parra-Izquierdo , L.K. Lozano-Rivera , S.D. Romero-Arias","doi":"10.1016/j.rgmxen.2025.12.011","DOIUrl":"10.1016/j.rgmxen.2025.12.011","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 134-137"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145992153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D.K. Tapia Calderón , E. Llop Herrera , J.L. Calleja Panero , E.S. García Jiménez , G. Castro Narro , J.A. Velarde-Ruiz Velasco
{"title":"The future of splenic elastography: Is it a valuable tool for personalized treatment?","authors":"D.K. Tapia Calderón , E. Llop Herrera , J.L. Calleja Panero , E.S. García Jiménez , G. Castro Narro , J.A. Velarde-Ruiz Velasco","doi":"10.1016/j.rgmxen.2026.04.002","DOIUrl":"10.1016/j.rgmxen.2026.04.002","url":null,"abstract":"<div><div>Portal hypertension is the main determinant of prognosis in cirrhosis of the liver. The gold standard for its evaluation is hepatic venous pressure gradient measurement. Because it is an invasive test performed only at highly specialized centers, noninvasive tools for the detection of portal hypertension have been developed. One of the most relevant is vibration-controlled transient elastography (FibroScan®; Echosens, Paris, France). Liver stiffness measurement is the most widely utilized and validated noninvasive tool, although more recent studies suggest spleen stiffness measurement correlates better with the hepatic venous pressure gradient. In the present narrative review, a comprehensive search of the literature was carried out on the PubMed/MEDLINE, Embase, and Cochrane CENTRAL databases, complemented by manual reference screening, to critically analyze the available evidence on splenic elastography in the noninvasive evaluation of portal hypertension. The following topics are addressed: the clinical impact of portal hypertension evaluation, the role of liver elastography as a noninvasive strategy, and the different applications of splenic elastography in the evaluation of portal pressure, including the diagnosis of clinically significant portal hypertension and severe portal hypertension, the prediction of esophageal varices and high-risk varices, clinical decompensation and recompensation risk assessment, and the usefulness of spleen stiffness measurement in monitoring the response to beta blocker therapy.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 76-88"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147870780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C.J. Toranzo-González, F. Rojas-Mendoza, N.E. Aguilar-Olivos
{"title":"Gastric metastatic lesions due to Burkitt lymphoma","authors":"C.J. Toranzo-González, F. Rojas-Mendoza, N.E. Aguilar-Olivos","doi":"10.1016/j.rgmxen.2025.07.001","DOIUrl":"10.1016/j.rgmxen.2025.07.001","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 118-120"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Svyryd , L.F. Uscanga-Domínguez , A. Ángeles-Ángeles , O.E. Falcón-Antonio , I. Domínguez-Rosado , C. Chan-Núñez , E.E. Huerta-Ávila , P. Rodríguez-García , E. Rodarte-López , O.M. Mutchinick
{"title":"Solid pseudopapillary tumor of the pancreas: Clinical, histopathological, and molecular findings in a cohort of Mexican patients","authors":"Y. Svyryd , L.F. Uscanga-Domínguez , A. Ángeles-Ángeles , O.E. Falcón-Antonio , I. Domínguez-Rosado , C. Chan-Núñez , E.E. Huerta-Ávila , P. Rodríguez-García , E. Rodarte-López , O.M. Mutchinick","doi":"10.1016/j.rgmxen.2026.04.001","DOIUrl":"10.1016/j.rgmxen.2026.04.001","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Solid pseudopapillary tumor of the pancreas (SPTP) is a rare pancreatic neoplasm of low malignant potential. It predominantly affects young women and raises ongoing questions about its origin and behavior. We aimed to evaluate somatic mutations of the β-catenin (<em>CTNNB1)</em> gene in Mexican patients with SPTP and assess clinical and molecular genotype-phenotype correlations in this rare tumor.</div></div><div><h3>Materials and methods</h3><div>A cross-sectional study of SPTP patients (1997–2023) was conducted at a tertiary care medical center. Tumor and non-affected pancreatic tissue samples underwent staining, immunohistochemistry testing, DNA extraction, and <em>CTNNB1</em> gene exon-3 sequencing.</div></div><div><h3>Results</h3><div>Of the 37 cases of SPTP studied, 36 were female, and one was male. Most tumors of variable sizes occurred in the pancreatic head or tail (78.4%). Immunohistochemical studies always revealed β-catenin expression and pathological analysis confirmed lymph node invasion. <em>CTNNB1</em> gene sequencing showed mutations in 34 of 37 tumors (91.9%), exclusively affecting codons 32, 33, 34, and 37.</div></div><div><h3>Conclusions</h3><div>The results show clinical and immunohistochemical associations with pancreatic tumor location, tissue invasion, and specific gene mutations. These findings highlight the prevalence of <em>CTNNB1</em> mutations in SPTP and underscore the significance of examining population diversity in rare tumor research to determine the likelihood of clinical and molecular correlations for personalized treatment.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 34-43"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of physical frailty and quality of food consumption in patients with HCV-related liver disease","authors":"M. Motamedrad, A.J. Montano-Loza","doi":"10.1016/j.rgmxen.2025.12.015","DOIUrl":"10.1016/j.rgmxen.2025.12.015","url":null,"abstract":"","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 1-4"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147870791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Zayas-Bórquez, J. Canto-Losa, E. Posadas-Trujillo, N. Salgado-Nesme, O. Santes
{"title":"C-reactive protein and early diagnosis of anastomotic leakage in colorectal surgery: An evolving standard?","authors":"R. Zayas-Bórquez, J. Canto-Losa, E. Posadas-Trujillo, N. Salgado-Nesme, O. Santes","doi":"10.1016/j.rgmxen.2025.12.006","DOIUrl":"10.1016/j.rgmxen.2025.12.006","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Anastomotic leakage is a critical complication in colorectal surgery, significantly associated with postoperative morbidity and mortality. Early detection of at-risk patients is essential for optimizing clinical outcomes. The present study investigates the utility of C-reactive protein (CRP) as a predictive inflammatory biomarker for anastomotic leakage.</div></div><div><h3>Materials and methods</h3><div>A retrospective observational study was conducted at the <em>Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán</em>, analyzing 95 patients who underwent colorectal surgery within the time frame of March 2023 and July 2024. CRP levels were measured on postoperative days 1, 3, and 5. The predictive capacity was measured through ROC curves, determining the optimum cutoff points with the Youden index.</div></div><div><h3>Results</h3><div>CRP on day 3 showed an AUC of 0.91, with an optimum cutoff point of 18.69 mg/l (Youden index = 0.73). On day 5, the AUC was 0.93, with a cutoff point of 14.25 mg/l (Youden index = 0.73). Both measurements showed high sensitivity and specificity for predicting anastomotic leakage.</div></div><div><h3>Conclusion</h3><div>Elevated CRP levels on postoperative days 3 and 5 emerged as robust predictors of anastomotic leakage, potentially guiding early interventions and improving patient prognosis.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 29-33"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145879575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Castaño-Llano , L.J. Palacios , J.R. Jaramillo , M. Rodríguez , N. Cortés , J.M. Castro , C. Díaz , D. Restrepo , J.E. Puerta , I. Mejía , D. Palacio , O. Álvarez
{"title":"Post-endoscopy esophageal adenocarcinoma: Insights from a multicenter cohort in Colombia","authors":"R. Castaño-Llano , L.J. Palacios , J.R. Jaramillo , M. Rodríguez , N. Cortés , J.M. Castro , C. Díaz , D. Restrepo , J.E. Puerta , I. Mejía , D. Palacio , O. Álvarez","doi":"10.1016/j.rgmxen.2025.12.010","DOIUrl":"10.1016/j.rgmxen.2025.12.010","url":null,"abstract":"<div><h3>Introduction</h3><div>The incidence of esophageal adenocarcinoma (EAC) has increased. Although there are screening and surveillance programs, especially for patients with Barrett’s esophagus (BE), they have limited effectiveness in detecting early disease. Post-endoscopy esophageal adenocarcinoma (PEEC), diagnosed after previous negative endoscopies, raises concerns about the accuracy of current endoscopic practices in high-risk patients.</div></div><div><h3>Aims</h3><div>Primary aim: to estimate the rate of PEEC and analyze its characteristics in patients at three hospital centers in Medellín, Colombia.</div></div><div><h3>Specific aims</h3><div>• To compare characteristics between patients with PEEC and those diagnosed at the first endoscopy.</div><div>• Evaluate the prevalence of BE in the two cohorts and its relation to PEEC.</div><div>• Analyze the anatomic location of PEEC.</div></div><div><h3>Materials and methods</h3><div>An observational cohort study was conducted that included 473 patients diagnosed with esophageal cancer between 2012 and 2023 at three centers in Medellín, Colombia, 31 of whom had PEEC. Their demographic, clinical, and survival data were evaluated using the STROBE guidelines for cohort studies (pages 22–26).</div></div><div><h3>Results</h3><div>The PEEC rate was 6.6%. Patients with PEEC presented with fewer alarm symptoms (35% vs 63%, <em>p</em> = 0.002), a higher prevalence of BE (42% vs 23%, <em>p</em> = 0.016), and were diagnosed at an earlier stage of disease. The previous endoscopies failed to detect lesions, especially in the proximal esophagus.</div></div><div><h3>Conclusions</h3><div>PEEC is a frequent entity, especially in patients with BE and proximal lesions. Optimizing endoscopy through advanced imaging techniques and strict surveillance protocols is required.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"91 1","pages":"Pages 57-67"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}