Revista Colombiana de psiquiatria (English ed.)最新文献

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Association Between Suicidal Behaviour and Cannabis and Tranquilizer use, Depression, Aggression and Other Borderline Personality Traits Among Students in Sincelejo, Colombia 哥伦比亚Sincelejo学生自杀行为与大麻和镇静剂使用、抑郁、攻击性和其他边缘人格特征的关系。
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-07-01 DOI: 10.1016/j.rcpeng.2021.05.011
Kelly Romero-Acosta , Salomón Verhelst , Gillian A. Lowe , Garth E. Lipps , José Restrepo , Leodanis Fonseca
{"title":"Association Between Suicidal Behaviour and Cannabis and Tranquilizer use, Depression, Aggression and Other Borderline Personality Traits Among Students in Sincelejo, Colombia","authors":"Kelly Romero-Acosta ,&nbsp;Salomón Verhelst ,&nbsp;Gillian A. Lowe ,&nbsp;Garth E. Lipps ,&nbsp;José Restrepo ,&nbsp;Leodanis Fonseca","doi":"10.1016/j.rcpeng.2021.05.011","DOIUrl":"10.1016/j.rcpeng.2021.05.011","url":null,"abstract":"<div><h3>Objective</h3><p>This objective of this study is to examine the association between suicidal behaviour and substance use, depression, aggressiveness and borderline personality traits among adolescents from Sincelejo, a rural city in the north of Colombia.</p></div><div><h3>Methods</h3><p>This cross sectional study included 352 participants selected by purposive sampling, from a public and a private school located in Sincelejo, Sucre district, in the north of Colombia. Students ages ranged from 12 to 18 years old (mean, 15.09<!--> <!-->±<!--> <!-->1.82). The participants completed three screening tools: a socio-demographic questionnaire, a screening instrument to collect information related to the frequency of use of some substances, such as tobacco and cannabis, and a self-report inventory to assess various personality and psychopathology domains. A series of t-tests, ANOVA and linear regression analyses were conducted.</p></div><div><h3>Results</h3><p>Physical aggression (t<!--> <!-->=<!--> <!-->7.74; <em>p</em> &lt;<!--> <!-->0.01), cognitive depression (t<!--> <!-->=<!--> <!-->5.03; <em>p</em> &lt;<!--> <!-->0.01), affective depression (t<!--> <!-->=<!--> <!-->8.24; <em>p</em> &lt;<!--> <!-->0.01), affective instability (t<!--> <!-->=<!--> <!-->3.46; <em>p</em> &lt;<!--> <!-->0.01), few social relationships (t<!--> <!-->=<!--> <!-->3.36; <em>p</em> &lt;<!--> <!-->0.01), self-harm (t<!--> <!-->=<!--> <!-->3.45; <em>p</em>&lt;<!--> <!-->.01), cannabis and tranquilizer use (t<!--> <!-->=<!--> <!-->2.83; <em>p</em> &lt;<!--> <!-->0.05; and t<!--> <!-->=<!--> <!-->2.37; <em>p</em> &lt;<!--> <!-->0.05) had a significant independent relationship with suicidal behaviour. Aggression (t<!--> <!-->=<!--> <!-->2.59; <em>p</em> &lt;<!--> <!-->0.05), components of depression (t<!--> <!-->=<!--> <!-->9.03; <em>p</em> &lt;<!--> <!-->0.01) and borderline personality traits (t<!--> <!-->=<!--> <!-->4.12; <em>p</em> &lt;<!--> <!-->0.01) also predicted suicidal behaviour.</p></div><div><h3>Conclusions</h3><p>More longitudinal studies are needed in this area to identify the causal relations between the factors studied and the suicidal behaviour of young people in Sincelejo.</p></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 3","pages":"Pages 225-235"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Coexistence of different delusional misidentification syndromes in clinical practice: A case series 临床实践中不同妄想性误认综合征的共存:一个病例系列。
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-07-01 DOI: 10.1016/j.rcpeng.2021.05.007
Marta Migoya-Borja , Nora Palomar-Ciria , Fanny Cegla-Schvartzman , Santiago Ovejero , Enrique Baca-García
{"title":"Coexistence of different delusional misidentification syndromes in clinical practice: A case series","authors":"Marta Migoya-Borja ,&nbsp;Nora Palomar-Ciria ,&nbsp;Fanny Cegla-Schvartzman ,&nbsp;Santiago Ovejero ,&nbsp;Enrique Baca-García","doi":"10.1016/j.rcpeng.2021.05.007","DOIUrl":"10.1016/j.rcpeng.2021.05.007","url":null,"abstract":"<div><h3>Objective</h3><p>The objective of this study is to analyse the coexistence of several delusional misidentification syndromes in a clinical sample.</p></div><div><h3>Methods</h3><p>Over one year, a sample of six patients presenting two or more types of delusional misidentification syndromes was selected. All these patients were admitted to the psychiatric inpatient unit of a Spanish hospital.</p></div><div><h3>Results</h3><p>Despite the different diagnoses, the patients included presented different types of delusional misidentification syndromes, both hyperidentification and hypoidentification. Antipsychotic<span> treatment was not very effective against these delusional misidentification syndromes.</span></p></div><div><h3>Conclusions</h3><p>The coexistence of several delusional misidentification syndromes indicates that the aetiopathogenesis of the different types is similar. It is a field with important clinical implications, due to the poor response to treatment, as well as the possible medico-legal implications.</p></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 3","pages":"Pages 201-205"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GAD-7 Generalised Anxiety Disorder scale in Colombian medical professionals during the COVID-19 pandemic: Construct validity and reliability 新冠肺炎大流行期间哥伦比亚医疗专业人员的GAD-7一般性焦虑症量表:构建有效性和可靠性。
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-07-01 DOI: 10.1016/j.rcpeng.2021.06.011
Loida Camargo , Jorge Herrera-Pino , Salomon Shelach , Marcio Soto-Añari , Maria F. Porto , Monica Alonso , Miguel González , Oscar Contreras , Nicole Caldichoury , Miguel Ramos-Henderson , Pascual Gargiulo , Norman López
{"title":"GAD-7 Generalised Anxiety Disorder scale in Colombian medical professionals during the COVID-19 pandemic: Construct validity and reliability","authors":"Loida Camargo ,&nbsp;Jorge Herrera-Pino ,&nbsp;Salomon Shelach ,&nbsp;Marcio Soto-Añari ,&nbsp;Maria F. Porto ,&nbsp;Monica Alonso ,&nbsp;Miguel González ,&nbsp;Oscar Contreras ,&nbsp;Nicole Caldichoury ,&nbsp;Miguel Ramos-Henderson ,&nbsp;Pascual Gargiulo ,&nbsp;Norman López","doi":"10.1016/j.rcpeng.2021.06.011","DOIUrl":"10.1016/j.rcpeng.2021.06.011","url":null,"abstract":"<div><h3>Introduction</h3><p>The detection of anxiety symptoms among health workers who care for patients infected with COVID-19 is a current priority. Fast and valid instruments are required for this population group. The objective is to establish the construct validity and reliability of the Generalised Anxiety Disorder (GAD-7) scale in Colombian doctors during the COVID-19 lockdown.</p></div><div><h3>Methods</h3><p>E-health study, in which cross-sectional data were collected online (n = 1030) from 610 COVID doctors and 420 non-COVID doctors, during the Colombian lockdown, between 20 April and 10 August 2020. Each subject was contacted, and they confirmed their participation, identity and professional role.</p></div><div><h3>Results</h3><p>A single factor factorial structure was found, made up of the 7 items of the instrument, which managed to explain 70% of the variance. The goodness of fit indices (RMSEA = 0.080; CFI = 0.995; SRMR = 0.053; p &lt; 0.001) showed an “acceptable” unidimensionality and adequate factor loadings in each item of the GAD-7, &gt;0.070. Finally, the internal consistency of the instrument was good, with a Cronbach’s alpha of 0.920 (95%IC, 8.80–9.71).</p></div><div><h3>Conclusions</h3><p>The GAD-7 is an instrument that presents adequate indicators of validity and reliability. It is an excellent tool that is reliable and easy and fast to use for the detection of generalised anxiety symptoms in medical personnel caring (or not) for patients infected with COVID-19.</p></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 3","pages":"Pages 245-250"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Does cognition predict the perceptions of older adults regarding self-stigma in seeking help? 认知能否预测老年人在寻求帮助时对自我耻辱的看法?
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-04-01 DOI: 10.1016/j.rcpeng.2021.10.004
Vaitsa Giannouli
{"title":"Does cognition predict the perceptions of older adults regarding self-stigma in seeking help?","authors":"Vaitsa Giannouli","doi":"10.1016/j.rcpeng.2021.10.004","DOIUrl":"10.1016/j.rcpeng.2021.10.004","url":null,"abstract":"","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 2","pages":"Pages 85-86"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with suicidal intent in economically active patients diagnosed with major depression 诊断为重度抑郁症的经济活动患者自杀意图的相关因素
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-04-01 DOI: 10.1016/j.rcpeng.2021.01.002
María Alejandra Betancur Díaz , Andrea Lorena Garzón Ladino , Alexie Vallejo Silva , Milton Murillo Pinto
{"title":"Factors associated with suicidal intent in economically active patients diagnosed with major depression","authors":"María Alejandra Betancur Díaz ,&nbsp;Andrea Lorena Garzón Ladino ,&nbsp;Alexie Vallejo Silva ,&nbsp;Milton Murillo Pinto","doi":"10.1016/j.rcpeng.2021.01.002","DOIUrl":"10.1016/j.rcpeng.2021.01.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Every 40<!--> <span>s, one person in the world commits suicide. As such, suicide is considered a public health problem, and prior suicide attempt is one of the risk factors associated with completed suicide. Despite the strategies implemented and the studies carried out, in Colombia suicide figures are on the rise, more markedly in the economically active population.</span></p></div><div><h3>Objective</h3><p>To identify the sociodemographic, family, personal, economic and religious factors associated with suicide attempt in patients of productive age (18–62 years old) in a mental health institution in Bogota, Colombia.</p></div><div><h3>Methods</h3><p>An analytical prevalence study was conducted at the Nuestra Señora de la Paz mental health clinic in Bogota. To explore the relationship between the factors described and suicide attempt, a review of 350 medical records of the selected population was carried out.</p></div><div><h3>Results</h3><p>In total, 37.7% of the sample presented a suicide attempt. Associations were found between the suicide attempt and higher education than primary school (PR<!--> <!-->=<!--> <!-->0.47 [0.23−0.97]), no economic income (PR<!--> <!-->=<!--> <!-->1.72 [1.13−2.61]), no partner (PR<!--> <!-->=<!--> <!-->2.10 [1.33−3.32]), alcohol consumption (<em>P</em> <!-->=<!--> <!-->.045), hallucinogen use (PR<!--> <!-->=<!--> <!-->2.39 [0.97−3.43]) and the presence of personality disorder (PR<!--> <!-->=<!--> <!-->1.93 [1.11−3.34]).</p></div><div><h3>Conclusions</h3><p>The results of the study are similar to those previously described in other studies around the world. There is a need to recognise and address various factors associated with suicide attempt in depressed patients in order to implement promotion and prevention actions, early identification and specific interventions that have an impact on the numbers of completed suicide in the country.</p></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 2","pages":"Pages 87-92"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9884037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electroconvulsive Therapy Impact on Memory Performance in Patients With Depression 电休克治疗对抑郁症患者记忆表现的影响
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-04-01 DOI: 10.1016/j.rcpeng.2021.03.004
Oscar Mauricio Castaño Ramírez , Carlos Andrés Gómez Bedoya , Rocío Lemos Buitrago , Juan Carlos Castro Navarro , Luis Guillermo Valencia Aristizábal , Alexandra Valderrama Sánchez , Pablo Felipe Botero , Mayra Alejandra Reinoso Gualtero
{"title":"Electroconvulsive Therapy Impact on Memory Performance in Patients With Depression","authors":"Oscar Mauricio Castaño Ramírez ,&nbsp;Carlos Andrés Gómez Bedoya ,&nbsp;Rocío Lemos Buitrago ,&nbsp;Juan Carlos Castro Navarro ,&nbsp;Luis Guillermo Valencia Aristizábal ,&nbsp;Alexandra Valderrama Sánchez ,&nbsp;Pablo Felipe Botero ,&nbsp;Mayra Alejandra Reinoso Gualtero","doi":"10.1016/j.rcpeng.2021.03.004","DOIUrl":"10.1016/j.rcpeng.2021.03.004","url":null,"abstract":"<div><h3>Introduction</h3><p>The safety of electroconvulsive therapy has improved greatly over the last decades, making the potentially adverse effects on memory and other neurocognitive functions the main clinical aspect of concern in the present. In Colombia, the general population and healthcare professionals (even some psychiatrists) seem to have mostly negative opinions towards electroconvulsive therapy treatment, but maybe this could be reconsidered if more information is provided; therefore, the aim of the present study was to evaluate the changes in memory and the severity of the symptoms in a group of patients with severe depression before and after electroconvulsive therapy.</p></div><div><h3>Methods</h3><p>Twenty-three patients ranging in age from 23 to 70 years from the electroconvulsive therapy service at the San Juan de Dios Clinic (Manizales, Colombia) were recruited in order to assess the effect of electroconvulsive therapy on memory in patients with severe depression. Depressive symptoms and memory were assessed with the Hamilton Depression Scale (HAMD) and Rey Auditory Verbal Learning Test (RAVLT), respectively. The assessment was administered to participants before the initial treatment of electroconvulsive therapy series (0-1 day) and 2 days after their last treatment.</p></div><div><h3>Results</h3><p>Electroconvulsive therapy resulted in significant improvement in the rating of depression. There were no significant differences in the five learning trials, delayed recall, learning and forgetting scores from pre-treatment to post-treatment. Significant pre-treatment/post-treatment differences were found in the delayed recognition trial.</p></div><div><h3>Conclusions</h3><p>Pre- and post- electroconvulsive therapy cognitive assessment is a feasible and useful procedure. In general, memory performance does not worsen after electroconvulsive therapy in patients with depression. Only delayed recognition is affected a few days following electroconvulsive therapy, particularly in patients with low educational level and bitemporal (BT) electrode placement.</p></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 2","pages":"Pages 107-112"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9937653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
One hundred and fifty years of hebephrenia. A review 患了150年的肝炎。回顾
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-04-01 DOI: 10.1016/j.rcpeng.2021.07.004
Daniel R. Martínez
{"title":"One hundred and fifty years of hebephrenia. A review","authors":"Daniel R. Martínez","doi":"10.1016/j.rcpeng.2021.07.004","DOIUrl":"10.1016/j.rcpeng.2021.07.004","url":null,"abstract":"<div><h3>Introduction</h3><p><span>The publication of Hecker's article on hebephrenia in 1871 was a fundamental milestone for </span>clinical psychiatry. Despite the initial recognition, many voices were raised against this diagnostic category and its limits were attenuated throughout the 20th century until its disappearance at the beginning of this century (along with the other subtypes of schizophrenia) in the DSM and ICD.</p></div><div><h3>Discussion</h3><p>However, given the consistency of the clinical picture, there is the possibility of other criteria emerging that would lead its systematic study to continue or recommence. In this sense, the concepts of deficit schizophrenia, hebephrenia as a replacement for schizophrenia as a whole, and Leonhard's hebephrenias as systematic schizophrenias stand out. This article discusses the main diagnostic conflicts of the category of hebephrenia over time, with emphasis on the problems of recent decades.</p></div><div><h3>Conclusions</h3><p>The concept of hebephrenia has begun to be revalued in recent years, and the concepts of deficit schizophrenia, of hebephrenia as a major category, and of systematic hebephrenias allow further investigation of this foundational picture of clinical psychiatry.</p></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 2","pages":"Pages 139-145"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9884035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental health in the current social scenario in Colombia 哥伦比亚当前社会状况下的心理健康
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-04-01 DOI: 10.1016/j.rcpeng.2023.07.001
Hernando Santamaría-García
{"title":"Mental health in the current social scenario in Colombia","authors":"Hernando Santamaría-García","doi":"10.1016/j.rcpeng.2023.07.001","DOIUrl":"10.1016/j.rcpeng.2023.07.001","url":null,"abstract":"","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 2","pages":"Pages 83-84"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9878584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Burns in the context of a shared psychotic disorder in a Colombian referral centre: A case report 在哥伦比亚转诊中心共享精神障碍的背景下烧伤:一个病例报告
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-04-01 DOI: 10.1016/j.rcpeng.2021.04.004
Diego Fernando Alarcón Ariza , Laura Cristina Zambrano Jerez , Carlos Enrique Ramírez Rivero , Jorge Andrés Niño García , Adriana Catalina Ruiz Quecan , Gonzalo Andrés Domínguez Alvarado
{"title":"Burns in the context of a shared psychotic disorder in a Colombian referral centre: A case report","authors":"Diego Fernando Alarcón Ariza ,&nbsp;Laura Cristina Zambrano Jerez ,&nbsp;Carlos Enrique Ramírez Rivero ,&nbsp;Jorge Andrés Niño García ,&nbsp;Adriana Catalina Ruiz Quecan ,&nbsp;Gonzalo Andrés Domínguez Alvarado","doi":"10.1016/j.rcpeng.2021.04.004","DOIUrl":"10.1016/j.rcpeng.2021.04.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Shared paranoid disorder is characterised by the development of psychotic symptoms in people who have a close affective bond with a subject suffering from a mental disorder. This case is the first case of burn injuries reported in the context of this disorder.</p></div><div><h3>Case</h3><p>We describe a young couple, with a similar pattern of burns caused by contact with a griddle. The injuries are the result of the aggression caused by a relative of one of them, who presented psychotic symptoms, related to the previously undiagnosed spectrum of schizophrenia.</p></div><div><h3>Conclusions</h3><p>The impact of this condition encompasses social, physical and psychological components, requiring multidisciplinary management and a high index of diagnostic suspicion.</p></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 2","pages":"Pages 156-160"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10239984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is structural connectivity different in child and adolescent relatives of patients with bipolar disorder? A narrative review according to studies with DTI 双相情感障碍患者的儿童和青少年亲属的结构连通性不同吗?根据DTI的研究进行叙述性回顾
Revista Colombiana de psiquiatria (English ed.) Pub Date : 2023-04-01 DOI: 10.1016/j.rcpeng.2021.01.003
Paula Robledo-Rengifo , Juan David Palacio-Ortiz , Jenny García-Valencia , Cristian Vargas-Upegui
{"title":"Is structural connectivity different in child and adolescent relatives of patients with bipolar disorder? A narrative review according to studies with DTI","authors":"Paula Robledo-Rengifo ,&nbsp;Juan David Palacio-Ortiz ,&nbsp;Jenny García-Valencia ,&nbsp;Cristian Vargas-Upegui","doi":"10.1016/j.rcpeng.2021.01.003","DOIUrl":"10.1016/j.rcpeng.2021.01.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Bipolar disorder<span><span> (BD) has been associated with a decrease in white matter integrity. Diffusion tensor imaging (DTI) studies have enabled these changes to be elucidated with higher quality. Due to BD’s high </span>heritability, some studies have been conducted in relatives of BD patients looking at white matter integrity, and have found that structural connectivity may also be affected. This alteration has been proposed as a potential BD biomarker of vulnerability. However, there are few studies in children and adolescents.</span></p></div><div><h3>Objective</h3><p>To conduct a review of the literature on changes in white matter integrity determined by DTI in high-risk children and adolescents.</p></div><div><h3>Results</h3><p><span>Brain structural connectivity in the paediatric population is described in studies using DTI. Changes in the </span>myelination<span><span> process from its evolution within normal neurodevelopment to the findings in </span>fractional anisotropy (FA) in BD patients and their high-risk relatives are also described.</span></p></div><div><h3>Conclusions</h3><p>Studies show that both BD patients and their at-risk relatives present a decrease in FA in specific brain regions. Studies in children and adolescents with a high risk of BD, indicate a reduced FA in axonal tracts involved in emotional and cognitive functions. Decreased FA can be considered as a vulnerability biomarker for BD.</p></div>","PeriodicalId":74702,"journal":{"name":"Revista Colombiana de psiquiatria (English ed.)","volume":"52 2","pages":"Pages 146-155"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9878600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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