Reproduction and breeding最新文献

{"title":"Erratum regarding previously published articles","authors":"","doi":"10.1016/j.repbre.2023.10.004","DOIUrl":"https://doi.org/10.1016/j.repbre.2023.10.004","url":null,"abstract":"","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 4","pages":"Pages 197-198"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667071223000443/pdfft?md5=1977a2e59ee3a76ebd539e069eb97f96&pid=1-s2.0-S2667071223000443-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92014442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Queries on the article \"Maternal traditional Chinese medicine exposure and risk of congenital malformations\" and suggestions for teratogenicity research","authors":"Willow JH Liu ,&nbsp;Yongming Li ,&nbsp;Ashley Xia ,&nbsp;Dongyun Liang ,&nbsp;Arthur Yin Fan ,&nbsp;Guanhu Yang ,&nbsp;Sherman Gu ,&nbsp;Guoping Zheng ,&nbsp;Hong Su","doi":"10.1016/j.repbre.2023.09.003","DOIUrl":"https://doi.org/10.1016/j.repbre.2023.09.003","url":null,"abstract":"<div><p>Traditional Chinese Medicine (TCM) has a rich history spanning thousands of years, with its applications ranging from treating female infertility and recurrent pregnancy loss to managing nausea and vomiting of pregnancy. Yet the safety of pregnant women consuming Chinese herbal medicine (CHM) still lacks sufficient modern clinical research data. On April 19, the journal Acta Obstetricia et Gynecologica Scandinavica published a research article titled \"Maternal traditional Chinese medicine exposure and risk of congenital malformations: a multi-center prospective cohort study.\" The study claimed that \"Periconceptional TCM exposure is associated with an increased risk of congenital malformation,\" drawing attention from both English and Chinese media outlets, which extensively reported and commented on the findings.</p><p>In response, various TCM organizations contested the research, asserting that it failed to adhere to fundamental standards of academic rigor, statistical analysis, and necessary methodologies to draw conclusions. International TCM practitioners and scholars thoroughly examined the article, uncovering multiple errors and arguing that these misleading conclusions significantly undermined the reputation of CHM. These scholars communicated their doubts directly to the corresponding author and the journal's chief editor, emphasizing that the article's conclusion was derived from secondary data analysis of another clinical research project and funding sources, therefore, called for withdrawal of the article. Eventually, the article was retracted due to flaws with the study design in collecting data on exposure to TCM in pregnant women, which affects the validity of the data to support the conclusions of the study.</p><p>This article conducts a comprehensive academic inquiry into the article, meticulously outlining the identified errors, discusses the reproductive toxicity of CHM, and provides suggestions for future research to evaluate the safety of pregnant women using CHM rigorously, emphasizing evaluation on teratogenicity research of CHM should not only be based on study using healthy animals, but also incorporate clinical epidemiological research and disease-syndrome-based toxicology.</p></div>","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 4","pages":"Pages 177-183"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667071223000388/pdfft?md5=3d9bd35a50c01bac73c893747d862c53&pid=1-s2.0-S2667071223000388-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92014438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: A comparative study of muscle nutrition and intermuscular bone number in improved diploid carp","authors":"Yahui Chen ,&nbsp;Zhi Xiong ,&nbsp;Peizhi Qin ,&nbsp;Qilong Liu,&nbsp;Yi Fan,&nbsp;Qinglin Xu,&nbsp;Xin Wang,&nbsp;Zhipeng Yang,&nbsp;Wuhui Li,&nbsp;Ming Wen,&nbsp;Fangzhou Hu,&nbsp;Kaikun Luo,&nbsp;Shi Wang,&nbsp;Shaojun Liu","doi":"10.1016/j.repbre.2023.10.001","DOIUrl":"https://doi.org/10.1016/j.repbre.2023.10.001","url":null,"abstract":"","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 4","pages":"Page 176"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667071223000406/pdfft?md5=e4f23374c8c40f44656a990c15dd3447&pid=1-s2.0-S2667071223000406-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92014441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and analysis of senescence-related genes in caudal fin cells of triploid crucian carp","authors":"Canhui Jiang ,&nbsp;Zhen Huang ,&nbsp;Lingwei Tang ,&nbsp;Fangyuan Peng ,&nbsp;Yamei Xiao","doi":"10.1016/j.repbre.2023.10.002","DOIUrl":"https://doi.org/10.1016/j.repbre.2023.10.002","url":null,"abstract":"<div><p>This research aims to identify the hub genes associated with the senescence of triploid caudal fin cells. Transcriptomic data are obtained from the high and low generation (P6, P60) of triploid crucian carp caudal fin cells by high-throughput sequencing technology. Initially, all differential genes between the high and low generations are screened, yielding 4140 significantly upregulated genes and 3724 significantly downregulated genes. Subsequently, an aging gene set containing 950 genes is downloaded from the CellAge database to extract the differentially expressed genes associated with caudal fin cell aging, totaling 29 genes. GO and KEGG enrichment analyses are performed on these 29 aging differential genes. The GO analysis shows enrichment mainly in cellular processes related to aging, such as regulation of cell division, chromatin organization, cell cycle regulation. KEGG analysis reveals that the 29 aging-related genes are primarily involved in cell cycle and cellular senescence pathways. A PPI network of aging-related genes is constructed using the STRING database and Cytoscape software. Top-ranked genes were identified by using Degree, MCC, MNC, and Closeness algorithms in the Cytohubba plugin in Cytoscape, resulting in hub genes <em>EZH2, JUN, MYD88, RBL2, BMP4, CCND1, NFKB2, MMP9.</em> Lastly, qRT-PCR validation of these eight hub genes further confirmed the involvement of four genes: <em>EZH2, RBL2, BMP4,</em> and <em>CCND1.</em> The hub gene screened in this study may become a potential biomarker of fish caudal fin cell senescence, which provides a valuable experimental basis for the senescence of fish caudal fin cells, especially the senescence of caudal fin cells in polyploid fish, and the reproduction and breeding improvement of polyploid fish. It also provides meaningful data for elucidating the molecular mechanism of polyploid formation in animals, as well as the formation of aging and tumour in human beings.</p></div>","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 4","pages":"Pages 169-175"},"PeriodicalIF":0.0,"publicationDate":"2023-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667071223000418/pdfft?md5=cf35f069308fb721b7814b63202cbd52&pid=1-s2.0-S2667071223000418-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92014437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcriptome analysis confirms aquatic animals has less risk by carrying on human respiratory viruses","authors":"Yuan Chen ,&nbsp;Tingsong Yue ,&nbsp;Guoliang Lin ,&nbsp;Xi Luo ,&nbsp;Huimin Yang ,&nbsp;Robert W. Murphy ,&nbsp;Siyuan Gao ,&nbsp;Jing Luo","doi":"10.1016/j.repbre.2023.09.002","DOIUrl":"https://doi.org/10.1016/j.repbre.2023.09.002","url":null,"abstract":"<div><p>Aquatic animals are an important source of food for humans, yet little is known about their potential to transfer zoonotic viruses. Multiple recent cases of SARS-CoV-2 from cold-chain aquatic food and environmental samples has evoked worldwide concerns, and even though these cases pale in comparison to poultry and livestock. To investigate the potential threat of food from aquatic animals, we map their transcriptomes to the genomes of human respiratory- and intestine-related viruses. Analyses only find an influenza virus sequence in a salmon (<em>Salmo salar</em>) skin transcriptome. BLAST and phylogenetic analyses identify this sequence as influenza A, and this likely owes to contamination from a worker. Thus, when prepared properly, aquatic animals can provide great nutritional benefits to humans while posing minimal health risks.</p></div>","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 4","pages":"Pages 161-168"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49725637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex biased expression of Fem-1 in larval stages suggests its function in early sex differentiation of Litopeneaus vannamei","authors":"Yang Yu ,&nbsp;Yue Wang ,&nbsp;Xinjia Lv ,&nbsp;Shihao Li ,&nbsp;Fuhua Li","doi":"10.1016/j.repbre.2023.09.004","DOIUrl":"https://doi.org/10.1016/j.repbre.2023.09.004","url":null,"abstract":"<div><p>The Pacific white shrimp <em>Litopenaeus vanname</em>i (<em>L. vanname</em>i) is an economically important species worldwide. As females exhibit a faster growth rate than males, it is crucial to understand the mechanism of sex determination and differentiation for the purpose of mono-sex breeding in shrimp. The <em>feminization-1</em> gene (<em>Fem-1</em>) serves as a sex-determining gene in <em>Caenorhabditis elegans</em>, and the <em>Fem-1</em> family is implicated in sex development in several crustaceans. In this study, three <em>Fem-1</em> family members, namely <em>LvFem-1a</em>, <em>LvFem-1b</em>, and <em>LvFem-1c</em>, were identified and characterized in <em>L. vanname</em>i. Based on genetic sex marker, individuals were separated by sex during the early developmental stages. The expression profiles of these genes were analyzed in female or male larvae. Significant differences between females and males were observed during the early stages of development. In Zoea III or earlier stages, the expressions levels in males were significantly higher than those in females. Intriguingly, there was a shift towards higher expression in females during the mysis and post-larval stages. These findings indicate that the Zoea III stage may be crucial for sex differentiation in shrimp. In addition, the analysis of gene expression across various ovarian stages and tissues was conducted. Results showed that all three genes were highly expressed in the ovary, with particularly elevated levels in ovarian development stage II. These findings suggest that the <em>Fem-1</em> genes play a critical role in early ovary development. This study is the first research focusing on the sex-specific expression of sex differentiation genes in shrimp. The obtained results provide new insights into to the role of the <em>Fem-</em>1 gene family in sex differentiation and gonadal development.</p></div>","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 4","pages":"Pages 153-160"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49725636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of lotus-fish co-culture on the gut microbiome of Hefang crucian carp (Carassis auratus)","authors":"Shengnan Li ,&nbsp;Qianhong Gu ,&nbsp;Zhanxin Li ,&nbsp;Qianqian Zeng ,&nbsp;Hui Zhong ,&nbsp;Meiqi Liu ,&nbsp;Jiaoyu Chen ,&nbsp;Yi Zhou ,&nbsp;Shaojun Liu ,&nbsp;Shengbiao Hu","doi":"10.1016/j.repbre.2023.09.001","DOIUrl":"https://doi.org/10.1016/j.repbre.2023.09.001","url":null,"abstract":"<div><p>Gut microbiome plays an important role in host's development and reproduction. Lotus-fish co-culture (LFC) is a popular integrated agriculture–aquaculture farming system in China. However, there is still a relative dearth of information on how changes of aquaculture modes will affect the fish gut microbiome. In the present study, metagenomic sequencing was used to compare gut bacteria of the hybrid fish Hefang crucian carp (<em>Carassius cuuieri</em> ♀ × <em>C. auratus</em> var. red ♂) cultured in LFC and intensive pond culture (IPC) systems. The results indicated that aquaculture modes exerted great influences on the fish gut bacterial community. A significantly higher gut bacterial diversity was found in LFC than that in IPC (<em>P</em> &lt; 0.05). The relative abundances of Actinobacteria and Chloroflexi were apparently higher in LFC than those in IPC, whereas Planctomycetota, Firmicutes, and Verrucomicrobia showed opposite patterns. Besides, gut bacterial metabolic potentials involved in energy metabolism, carbohydrate metabolism, amino acid metabolism, environmental information processing, and cellular processes were significantly increased in LFC compared to those in IPC. On the contrary, the bacterial functional potentials related to nucleotide metabolism, DNA mismatch repair, as well as homologous recombination were significantly stimulated in the IPC system. Source‐tracking analysis suggested that fish gut bacterial community in IPC was originated mainly from water sources, whereas the gut bacterial community in LFC was originated from more unknown sources and soil sources. Our results provided new insight into the influence of aquaculture modes on the microbial community diversity and functionality in aquatic animals and highlighted the importance of environment microbiome in reshaping the gut microbes.</p></div>","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 3","pages":"Pages 143-151"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49754922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The kiss2/kiss2r system directly modulates the activity of the pituitary gland in largemouth bass (Micropterus salmoides)","authors":"Wuhui Li ,&nbsp;Yan Miao ,&nbsp;Zexun Zhou ,&nbsp;Shi Wang,&nbsp;Fangzhou Hu,&nbsp;Zhongyuan Shen,&nbsp;Lei Zeng,&nbsp;Jie Hu,&nbsp;Ping Wu,&nbsp;RuRong Zhao,&nbsp;Min Tao,&nbsp;Chun Zhang,&nbsp;Qinbo Qin,&nbsp;Shaojun Liu","doi":"10.1016/j.repbre.2023.06.003","DOIUrl":"10.1016/j.repbre.2023.06.003","url":null,"abstract":"<div><p>The kisspeptin system, which involves hypothalamic neuropeptides, plays pivotal roles in the regulation of teleost reproduction. A previous study suggested that the <em>kiss2</em>/<em>kissr2</em> system in largemouth bass (<em>Micropterus salmoides</em>) was involved in regulating gonadal development through the hypothalamus-pituitary-gonad (HPG) axis. However, whether the <em>kiss2</em>/<em>kiss2r</em> system directly regulates the activity of pituitary gland were not studied. This study aimed to elucidate the detailed mechanism of kisspeptin-induced effects on gonadotropin hormone-producing cells in vivo and in vitro. <em>In situ</em> hybridization analysis revealed very widespread expression of <em>kiss2r</em> mRNA in the optic tectum, hypothalamus and pituitary. In the pituitary, <em>kiss2r</em>-expressing cells were mainly located in the proximal pars distalis and pars intermedia, among which the <em>fshβ-</em> and <em>lhβ</em>-positive cells exhibited expression of <em>kiss2r</em> messengers. Furthermore, primary culture of pituitary cells and peptide administration experiments revealed that the Kiss2-10 peptide stimulates the expression of <em>fshβ</em> and <em>lhβ</em> and the secretion of FSH and LH in 24 h. In addition, histology analysis revealed that three injections of the Kiss2-10 peptide promoted ovary development and increased oocyte size but had little effect on testis development. These results suggested that the intrapituitary kisspeptinergic system, as a hypophysiotropic neuropeptide factor, directly modulates of gonadotroph function. This study will help uncover the reproductive endocrinology network and improve artificial breeding technology for largemouth bass.</p></div>","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 3","pages":"Pages 99-107"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44858168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human breast organoid models for lactation research","authors":"Jenny Lee ,&nbsp;Yan Liu ,&nbsp;Edward Ray ,&nbsp;Armando E. Giuliano ,&nbsp;Xiaojiang Cui","doi":"10.1016/j.repbre.2023.08.003","DOIUrl":"10.1016/j.repbre.2023.08.003","url":null,"abstract":"<div><p>The human mammary gland is the major organ involved in lactation. In the mammary gland, alveoli secrete milk and myoepithelial cells contract to propel the milk through branched structures called ducts and eventually to the nipple. It is through this process of lactation that infants receive milk, which is essential for proper infant growth and development. The lactation process is comprised of sophisticated interactive networks at the cellular level that are not well understood. Whereas the majority of published mammary gland lactation studies have relied on mouse mammary glands, recent advancements in techniques to study mammary glands enable <em>in vitro</em> reproduction of lactation using human-representative frameworks. Currently, the 3D breast organoid is the state-of-the-art model in human mammary gland research, utilizing induced pluripotent stem cells (iPSCs) or processed patient-derived breast tissues embedded in a special matrix that are then able to grow into complex structures that recapitulate aspects of native human breast tissue. Gaining comprehensive biological insight into the process of lactation through these breast tissue-mimetic 3D models is essential for further studies on lactation-associated human mammary gland diseases, human milk composition, and potential solutions to challenges in maternal milk accessibility. In this short review, the benefits and potential utility of 3D breast organoids in understanding the underlying science of lactation and advancing further human mammary gland studies are discussed.</p></div>","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 3","pages":"Pages 125-130"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10484298/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10239590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of dietary glutathione on growth performance, muscle quality and lipid metabolism of hybrid crucian carp (Carassius auratus cuvieri ♀ × Carassius auratus red var. ♂) fed a high-fat diet","authors":"Zhongtian Tang ,&nbsp;Chunyan Li ,&nbsp;Gang Xu ,&nbsp;Qiang Zhao ,&nbsp;Zehong Wei ,&nbsp;Shaojun Liu","doi":"10.1016/j.repbre.2023.07.001","DOIUrl":"10.1016/j.repbre.2023.07.001","url":null,"abstract":"<div><p>A 60-day feeding trial was conducted to investigate the influence of glutathione (GSH) on growth performance, lipid metabolism and muscle quality of hybrid crucian carp (initial body weight: 15.03 ± 0.11 g) fed a high-fat diet (HFD). Five experimental diets were prepared in this study: the control diet (6.17% fat), HFD (12.37% fat), and HFD with 200 mg/kg, 400 mg/kg and 600 mg/kg GSH supplementation, respectively. The results indicated that feeding HFD to hybrid crucian carp remarkably reduced weight gain rate (WGR), specific growth rate (SGR), total antioxidant capacity (T-AOC) and total superoxide dismutase (T-SOD) activities of serum and liver, glutathione peroxidase (GSH-Px) and glutathione reductase (GR) activities of liver, but significantly increased malondialdehyde (MDA) content of liver compared to the control group. After adding 200–600 mg/kg GSH to HFD, the WGR, SGR, as well as serum and liver T-AOC activity of hybrid crucian carp increased significantly. Moreover, the supplementation of 400 mg/kg GSH significantly increased the activities of T-SOD, catalase (CAT) of serum and liver, as well as the GSH-Px, glutathione-S-transferase (GST) and GR of liver, but decreased MDA content of serum and liver compared to the HFD. The HFD significantly increased muscle crude lipid, polyunsaturated fatty acids (PUFA) contents and fiber diameter, but decreased chewiness, gumminess, hardness and fiber density compared to the control group. The addition of 400–600 mg/kg GSH significantly increased muscle chewiness, gumminess, hardness, and decreased muscle fiber diameter of HFD-fed hybrid crucian carp. Meanwhile, the addition of 200–600 mg/kg GSH significantly reduced the mono-unsaturated fatty acids (MUFA) content and increased the PUFA content of muscle compared to the HFD. The HFD significantly up-regulated the expression of lipid synthesis genes (<em>dgat2</em> and <em>srebp1</em>) and down-regulated the expression of lipolysis genes (<em>lpl</em>, <em>hsl</em> and <em>acox1</em>) of liver compared to the control group. The addition of 400–600 mg/kg GSH significantly decreased the expression of lipid synthesis genes (<em>dgat2</em> and <em>srebp1</em>) and increased the expression of lipolysis genes (<em>hsl, lpl, acox1</em> and <em>pparα</em>) of HFD-fed hybrid crucian carp. This study demonstrated that GSH effectively ameliorated the decline of growth performance and muscle quality of hybrid crucian carp caused by HFD, and reduced the risk of liver lipid deposition of hybrid crucian carp by regulating the expression of genes related to liver lipid metabolism.</p></div>","PeriodicalId":74667,"journal":{"name":"Reproduction and breeding","volume":"3 3","pages":"Pages 89-98"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44928559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}