卵巢储备功能严重减退的高龄产妇接受中药治疗后成功产下活婴:病例报告

Xiaoxiong Shen
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引用次数: 0

摘要

女性的生育能力大约从 35 岁开始明显下降,40 岁以后下降得更快。年龄不仅会影响卵母细胞库的大小,还会影响生殖细胞的质量。尽管辅助生殖技术不断进步,但不孕症仍是高龄产妇面临的一项挑战。在此,我们介绍一例四十多岁的妇女在接受中医治疗后成功生下两个活产婴儿的病例。患者初次就诊时(43 岁)月经周期短,有卵巢储备功能减退的迹象(FSH:26.2 mIU/mL;AMH:0.23 ng/mL)。第一次分娩三年后(47 岁),患者出现了卵巢储备功能进一步减退的迹象(FSH:27.1 mIU/mL;AMH:0.07 ng/mL)。值得注意的是,经过五个月的中药治疗后,她再次成功怀孕,并生下了一个活胎。本病例表明,中药对改善激素平衡和生育能力有积极的临床作用。我们需要进一步研究中药在改善高龄产妇生育能力方面的药代动力学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Successful live births after Chinese herbal medicine treatment on a patient of advanced maternal age with severe diminished ovarian reserve: A case report

The fecundity of women decreases significantly beginning approximately at age 35 and decreases more rapidly after age 40. Age affects not only the size of the oocyte pool but also the quality of germ cells. Despite the continuous advancement of assisted reproductive technology, infertility remains a challenge for women of advanced maternal age. Here, we present a case of a woman in her forties who had two successful live births after treatment with Traditional Chinese Medicine. At her initial visit (at age 43), the patient presented with a short menstrual cycle and signs of a diminished ovarian reserve (FSH: 26.2 mIU/mL; AMH: 0.23 ng/mL). Three years after her first delivery (at age 47), the patient showed signs of further diminished ovarian reserve (FSH: 27.1 mIU/mL; AMH: 0.07 ng/mL). Notably, after five months of Chinese herbal medicine treatment, she achieved another successful pregnancy, and resulted in a live birth. This case demonstrates that Chinese herbal medicine can have a positive clinical impact on improving hormonal balance and fecundity. Further research is needed to investigate the pharmacokinetics of Chinese herbal medicine in improving fecundity for women of advanced maternal age.

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