Reports (MDPI)最新文献

{"title":"Adjunctive Autologous Platelet-Rich Plasma Activated with Autologous Thrombin Serum for a Refractory Below-Knee Amputation Stump Wound: A Case Report.","authors":"Khansa Shara, Hasan AlAjmi, Nada Baatiah, Sara Darag, Renad Bakhamis, Amr Abdelhakim","doi":"10.3390/reports9040351","DOIUrl":"https://doi.org/10.3390/reports9040351","url":null,"abstract":"<p><p><b>Background and Clinical Significance:</b> Refractory below-knee amputation (BKA) stump wounds can delay prosthetic rehabilitation. This report describes wound healing during multimodal care that included autologous platelet-rich plasma (PRP) activated with autologous thrombin serum (ATS); <b>Case Presentation:</b> A 33-year-old man with Charcot-Marie-Tooth disease and a persistent right BKA stump wound after surgical revisions underwent three PRP-ATS applications on 16 and 23 February and 8 March 2026. Collagen dressings were applied on 2 and 15 March, and compression was continued thereafter. The estimated wound volume decreased from 14.18 cm³ at baseline to 0.48 cm³ at week 3 (approximately 97%); advanced epithelialization was observed at week 4. Complete closure was documented on 16 April 2026, approximately eight weeks after treatment began. No treatment-related adverse events were reported. After closure, the patient was referred for prosthetic rehabilitation assessment; fitting and functional use were not documented; <b>Conclusions:</b> Healing was temporally associated with PRP-ATS as part of a multimodal treatment course. This single case supports the feasibility of the approach but cannot establish the independent efficacy of PRP-ATS.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13692453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salvaging a Telescopic-Crown-Retained Partial Denture Using a Novel Flexible Attachment System-A Case Report.","authors":"Florian Lipka, Maya Brink, Christian Behle, Rainer Lutz, Sarah-Maria Meier","doi":"10.3390/reports9040354","DOIUrl":"https://doi.org/10.3390/reports9040354","url":null,"abstract":"<p><p><b>Background and Clinical Significance:</b> Removable partial dentures still present a relevant treatment option in an aging population. With the exception of clasps, the vast majority of attachment systems available for anchoring these restorations on natural abutments requires invasive tooth preparations causing secondary problems such as caries and abutment tooth fractures. In cases where an abutment tooth cannot be salvaged, placing an implant and connecting the existing prosthesis to this implant presents a viable solution. While a common path of insertion has been established during initial fabrication, it is almost impossible to match this with a newly placed retentive element. In the case presented, a novel ball anchor that allows for compensatory movements was used as a retentive implant abutment for salvaging a removable partial prosthesis. <b>Case Presentation:</b> An 83-year-old, medically compromised male patient, restored with a removable partial denture, stabilized by one abutment tooth and two clasps in the mandible, suffered from a non-restorable fracture of the abutment tooth. After tooth extraction, immediate implant placement (MT implant, AlfaGate, Bonn, Germany), closed healing of the implant for three month, then second-stage implant surgery and soft tissue healing for another four weeks, the implant was connected to a novel flexible attachment system, the REFLEX abutment (Hader Solutions, Dublin, Ireland). Shaped as a retentive ball, the REFLEX abutment allows lateral movements of the male attachment part while maintaining vertical dimensions like rigid locator-type attachments. <b>Conclusions:</b> The retrofitting of the novel flexible attachment under an originally telescopic-crown-retained partial denture allowed for a successful conversion of the prosthesis while preserving prosthetic fit and retention for the patient.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Kawasaki Disease-Like Presentation in a Child with Concurrent Detection of Group A <i>Streptococcus</i> and Adenovirus: A Case Report on the Characterization of Physical Findings and Short-Interval Reassessment.","authors":"Masafumi Yamada, Etaro Hashimoto, Yoshifumi Yamada, Akihiro Nishi, Tetsuhiro Maeno, Seiji Kawamura","doi":"10.3390/reports9040355","DOIUrl":"https://doi.org/10.3390/reports9040355","url":null,"abstract":"<p><p><b>Background and Clinical Significance:</b> Kawasaki disease (KD) lacks specific diagnostic tests and requires early diagnosis and treatment to prevent coronary artery lesions. Concurrent infections may produce KD-like presentations; however, practical management of this time-sensitive uncertainty remains poorly described. <b>Case Presentation:</b> A previously healthy 4-year-old boy developed a rash after fever, rhinorrhea, cough, and a sore throat. On day 5, bilateral bulbar conjunctival injection, rash, palmar erythema, and fever met the four principal Japanese diagnostic criteria for KD. Purulent ocular discharge was accompanied by conjunctival injection, and the rash was scarlatiniform. Rapid antigen tests for group A <i>Streptococcus</i> (GAS) and adenovirus (AdV) were positive. Echocardiography revealed no coronary artery dilatation. The clinical presentation was considered most consistent with concurrent GAS and AdV infections, and amoxicillin was initiated. As incomplete KD remained possible, the patient was reassessed on day 7, 48 h later; all symptoms resolved. C-reactive protein was elevated (5.59 mg/dL), but none of the six supplemental laboratory criteria in the American Heart Association incomplete-KD algorithm were met. As the clinical support for KD decreased, observation was continued, with instructions to return if the principal features recurred. No KD-related symptoms occurred, and a telephone follow-up confirmed a favorable course. <b>Conclusions:</b> In children with multiple principal clinical features of KD and suspected co-infections, KD should not be excluded solely based on positive pathogen tests. Characterizing individual findings, including ocular discharge and rash morphology, and short-interval reassessment of the same findings within the therapeutic window for KD may help manage diagnostic uncertainty.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distal Radial Access for Thoracic Branch Endoprosthesis Deployment: Two Cases of Successful TEVAR with Left Subclavian Artery Revascularization.","authors":"Haidara Almansour, Mohammadhossein Ghasempourabadi, Darren Klass","doi":"10.3390/reports9040353","DOIUrl":"https://doi.org/10.3390/reports9040353","url":null,"abstract":"<p><p><b>Background and Clinical Significance:</b> Thoracic endovascular aortic repair (TEVAR) involving zone 2 of the aortic arch frequently necessitates left subclavian artery (LSA) revascularization to reduce the risk of neurologic and ischemic complications. If endovascular methods are employed, conventional upper extremity access via the brachial or axillary artery often requires surgical cutdown and carries meaningful access-site morbidity. Distal radial (snuffbox) access offers a less invasive percutaneous alternative, yet its use for thoracic branch endoprosthesis (TBE) deployment has only rarely been reported; <b>Case Presentation:</b> We present two patients who underwent successful zone 2 TEVAR with TBE implantation and LSA revascularization using a femoral-to-distal radial through-and-through wire technique. In both cases, the branch component was deployed via the distal radial artery with excellent angiographic results and preserved antegrade flow to the LSA. Neither patient experienced access-related complications; <b>Conclusions:</b> These cases demonstrate the technical feasibility and safety of distal radial access for TBE deployment in zone 2 TEVAR. This approach offers a less invasive alternative to conventional upper extremity access, potentially reducing vascular complications and facilitating earlier recovery.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Growth Failure and Delayed Puberty in an Adolescent with Previously Undiagnosed Advanced HIV Infection: A Case Report.","authors":"Nikolay Balgaranov, Teodora Marinova-Bulgaranova, Stanimira Elkina","doi":"10.3390/reports9040352","DOIUrl":"https://doi.org/10.3390/reports9040352","url":null,"abstract":"<p><p><b>Background and Clinical Significance:</b> Longstanding human immunodeficiency virus (HIV) may remain clinically unrecognized until adolescence. Growth failure, delayed puberty, and recurrent or atypical infections may represent manifestations of underlying immunodeficiency but can initially be attributed to other conditions. <b>Case Presentation:</b> A 16-year-old male, adopted at 4 years of age, was admitted with prolonged low-grade fever, chronic productive cough, and recurrent sinonasal symptoms. Marked growth retardation and absent pubertal development were also present. No perinatal or early-childhood medical records were available, and maternal HIV status could not be established. Laboratory investigations demonstrated severe CD4+ T-cell depletion, hypergammaglobulinemia, and elevated liver enzymes. Repeated SARS-CoV-2 antigen/PCR tests were positive, while anti-SARS-CoV-2 antibodies were undetectable. CT demonstrated chronic pansinusitis and hepatosplenomegaly. HIV infection was confirmed by positive ELISA and Western blot, with a plasma HIV RNA level of 127,721 copies/mL. The findings were consistent with advanced HIV infection with severe immunosuppression. Although the clinical history suggested longstanding infection, the timing and route of HIV acquisition could not be established. Similarly, the available SARS-CoV-2 results did not allow definitive differentiation between persistent infection and separate infection or reinfection episodes. Previous CMV IgG positivity had contributed to an earlier attribution of the hepatic abnormalities to CMV, although active CMV disease was not documented. <b>Conclusions:</b> Severe growth failure, absent pubertal development, recurrent or atypical infections, and profound CD4+ T-cell depletion should prompt consideration of underlying immunodeficiency, including HIV. In patients with incomplete medical records, previous diagnoses should be reassessed, especially when the clinical course remains unexplained.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13692430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cryptococcal Infection in Advanced HIV-Associated Immunosuppression-Case Series.","authors":"Isabela Ioana Loghin, Ion Cecan, Andrei Vâţă, Anton Knieling, Otilia-Elena Frăsinariu, Victor Daniel Dorobăţ, Vlad Hârtie, Carmen Mihaela Dorobăţ","doi":"10.3390/reports9040349","DOIUrl":"https://doi.org/10.3390/reports9040349","url":null,"abstract":"<p><p><b>Background and Clinical Significance:</b> Cryptococcal meningitis remains a life-threatening complication of advanced HIV infection. Its recognition can be challenging when neurological manifestations are nonspecific or cerebrospinal fluid inflammation is limited. This case series illustrates the diagnostic variability and therapeutic challenges encountered in five patients managed at a regional HIV/AIDS center in northeastern Romania. <b>Case Presentation:</b> Five men aged 26-69 years were hospitalized between November 2022 and March 2025 with HIV-associated cryptococcal disease involving the central nervous system. All had profound immunosuppression, with CD4+ T-cell counts of 6-31 cells/mm³. Clinical manifestations included headache, confusion, altered consciousness, and focal neurological deficits. Cerebrospinal fluid opening pressures were elevated, while inflammatory findings ranged from lymphocytic pleocytosis to an almost acellular profile. Microbiological investigations included direct microscopy, fungal culture, and molecular testing, according to availability. In one patient, culture confirmed <i>Cryptococcus neoformans</i> despite negative India ink microscopy and absent documented pleocytosis. Antifungal treatment included liposomal amphotericin B and fluconazole-based regimens, with treatment selection constrained by drug availability and organ dysfunction. Three cases had fatal outcomes during hospitalization. <b>Conclusions:</b> Cryptococcal meningitis should remain a diagnostic consideration in profoundly immunosuppressed patients with neurological symptoms, even when initial microscopy is negative or cerebrospinal fluid inflammation is minimal. These cases emphasize the importance of complementary microbiological investigations, assessment and management of intracranial pressure, reliable access to recommended antifungal regimens, and appropriate timing of antiretroviral therapy.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13692328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subaxial Vertebral Artery Entrapment by Thyroid Cartilage and C5: Why Radiologists Should Think Beyond Bow Hunter's Syndrome-A Case Report.","authors":"Farnaz Delavari, Patrik Michel, Vincent Dunet, Guillaume Fahrni","doi":"10.3390/reports9040350","DOIUrl":"https://doi.org/10.3390/reports9040350","url":null,"abstract":"<p><p><b>Background and Clinical Significance</b>: Bow Hunter's syndrome is an uncommon cause of vertebrobasilar insufficiency caused by dynamic vertebral artery narrowing during head rotation or extension. It is classically described at the atlantoaxial level, whereas subaxial compression is less recognised. Thyroid cartilage-related vertebral artery compression is particularly rare and may mimic vertebral artery dissection on static imaging. This case highlights the need to distinguish anatomical conflict from clinically causal haemodynamic compression. <b>Case Presentation</b>: A 51-year-old man with vascular risk factors and a well-anticoagulated mechanical aortic valve presented with three transient ischaemic attacks within two hours, including left-hand paraesthesia, right hemianopia, transient aphasia, and right-hand paraesthesia. Symptoms occurred spontaneously, without clear relation to head or neck movement or trauma. Doppler ultrasound showed normal carotid and vertebral flow. CT angiography demonstrated focal stenosis of the right vertebral artery at the V1-V2 junction caused by an osteocartilaginous \"pincer\" between the right thyroid cartilage ala and the C5 transverse process. The axial appearance mimicked vertebral artery dissection, but multiplanar CTA and contrast-enhanced MRA supported external indentation without mural haematoma, intimal flap, pseudoaneurysm, or double lumen. Perfusion CT showed no focal hypoperfusion, and diffusion-weighted MRI showed no acute infarct. Because symptoms were not positional and competing embolic risk factors were present, conservative management was chosen. <b>Conclusions</b>: Thyroid cartilage-related subaxial vertebral artery compression is a rare diagnostic pitfall. Static imaging may suggest dissection or Bow Hunter's syndrome, but causality should not be inferred without compatible symptoms, exclusion of alternative mechanisms, and, when needed, dynamic confirmation.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of Failure After Postoperative Radiotherapy for WHO Grade 2-3 Meningiomas: A Single-Institution Experience.","authors":"Mitsutoshi Ooishi, Osamu Togao, Hiroshi Ito, Fumitaka Yoshioka, Tatsuya Abe","doi":"10.3390/reports9040348","DOIUrl":"https://doi.org/10.3390/reports9040348","url":null,"abstract":"<p><p><b>Background/Objectives</b>: World Health Organization (WHO) Grade 2-3 meningiomas have high recurrence rates despite postoperative radiotherapy. This study aimed to characterize patterns of failure and clinical outcomes after postoperative external beam radiotherapy. <b>Methods</b>: We retrospectively analyzed 10 patients with WHO Grade 2 (n = 6) or Grade 3 (n = 4) meningiomas treated at a single institution between January 2017 and May 2024. Nine patients underwent gross total resection. Radiotherapy was delivered using three-dimensional conformal radiotherapy (n = 6) or intensity-modulated radiotherapy (n = 4), with a median dose of 60 Gy in 30 fractions. Recurrence patterns were assessed relative to the high-dose region. <b>Results</b>: The 1- and 3-year overall survival rates were 90% (95% CI, 47-99%) and 79% (95% CI, 38-94%), respectively; corresponding local control rates were 70% (95% CI, 33-89%) and 39% (95% CI, 7-71%), respectively. Recurrence occurred in six patients, predominantly within the high-dose region. Acute toxicities were limited to Grade 1 radiation dermatitis. During follow-up, Grade 3 seizures occurred in three patients, and worsening of pre-existing Grade 2 paresis occurred in four patients. Two seizure events and two cases of worsening paresis were considered more likely related to recurrent or progressive disease, whereas attribution of the remaining neurological events to radiotherapy was uncertain. <b>Conclusions</b>: Despite postoperative radiotherapy, local control remained limited in this small, single-institution series, with a predominance of in-field recurrence. This pattern raises the possibility that tumor biological factors, in addition to technical and treatment-related factors, may contribute to treatment failure in WHO Grade 2-3 meningiomas. These findings are exploratory and warrant validation in larger studies incorporating molecular stratification and standardized treatment approaches.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13692445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double Iatrogenic Ethmoid-Orbito-Frontal Mucocele: The Role of Neuronavigation System in Revision of Endoscopic Sinus Surgery-A Case Report.","authors":"Chiara Rustichelli, Eleonora Ghessa, Alessandro Serrone, Guido Cavigioli, Giovanni Cavallo, Gian Luca Fadda","doi":"10.3390/reports9040347","DOIUrl":"https://doi.org/10.3390/reports9040347","url":null,"abstract":"<p><p><b>Background and Clinical Significance</b>: Frontal sinus disease remains one of the most challenging conditions in rhinology due to its complex and variable anatomy and high tendency toward postoperative stenosis. Paranasal sinus mucoceles are uncommon, delayed complications following functional endoscopic sinus surgery (FESS), most often involving the frontal or anterior ethmoidal sinuses. They may arise from obstruction or scarring of natural drainage pathways, producing recurrent sinusitis or headache; <b>Case Presentation</b>: A 21-year-old male presented with persistent left-sided frontal headache and nasal obstruction after two previous FESS procedures. Radiologically, CT and MRI demonstrated chronic left-sided sinonasal inflammatory disease and two frontal-ethmoidal mucoceles. Revision endoscopic sinus surgery was performed with an image-guided (neuronavigation-assisted) technique, including Draf IIb frontal sinusotomy, mucocele marsupialization, and corrective septoplasty. The postoperative course was uneventful with rapid clinical improvement; <b>Conclusions</b>: Double postoperative mucoceles following ESS are rare. Neuronavigation-assisted revision surgery can be used for effective management in scarred, anatomically distorted sinus regions. However, this single case cannot establish superiority over conventional endoscopic guidance or demonstrate an effect on safety, efficacy, or recurrence.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13692416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coexisting Sigmoid Volvulus and Acute Meckel's Diverticulitis Associated with a Fibrous Band: A Case Report.","authors":"Sergiu Balan, Claudiu Octavian Ungureanu, Razvan A Stoica, Floris Cristian Stanculea, Niculae Iordache","doi":"10.3390/reports9040344","DOIUrl":"https://doi.org/10.3390/reports9040344","url":null,"abstract":"<p><p><b>Background and Clinical Significance:</b> Meckel's diverticulum is a remnant of the omphalomesenteric duct, arising from an incomplete obliteration of the embryonic vitelline duct, which connects the fetal gut to the yolk sac, typically regressing between the fifth and seventh weeks of gestation. There are many mechanisms for bowel obstruction arising from a Meckel's diverticulum. Therefore, early diagnosis and treatment are the keys to prevent intestinal gangrene and perforation; <b>Case Presentation:</b> We report the management of sigmoid volvulus associated with acute Meckel's diverticulitis and a fibrous band in an 85-year-old patient with multiple comorbidities and very high perioperative risk. Sigmoid volvulus was the mechanical cause of intestinal obstruction, whereas an inflamed Meckel's diverticulum associated with a fibrous band extending toward the anterior abdominal wall was identified during surgical exploration. No twisting or mechanical obstruction of the distal ileum was observed. Histopathological examination subsequently confirmed acute Meckel's diverticulitis. The unusual coexistence of these findings, together with the diagnostic and therapeutic challenges posed by the patient's severe comorbidities, prompted us to report this case; <b>Conclusions:</b> Although no direct mechanical relationship between Meckel's diverticulum and sigmoid torsion was demonstrated, their coexistence raises a hypothesis of a potential pathophysiological interaction; however, any such relationship remains hypothesis-generating only. Identification of one apparent cause of intestinal obstruction should not preclude systematic evaluation for concomitant pathology, particularly when the clinical, radiological, operative, and inflammatory findings are not fully explained by a single diagnosis.</p>","PeriodicalId":74664,"journal":{"name":"Reports (MDPI)","volume":"9 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13692488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149278513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}