Pediatric health, medicine and therapeutics最新文献

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Therapeutic Management Strategies Among Immunocompetent Infants with Nontuberculous Mycobacterial Pulmonary Infection. 免疫功能正常婴儿非结核性分枝杆菌肺部感染的治疗管理策略。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-07-16 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S513904
Alice Bai, Hari Dandapani, Amrita Dosanjh
{"title":"Therapeutic Management Strategies Among Immunocompetent Infants with Nontuberculous Mycobacterial Pulmonary Infection.","authors":"Alice Bai, Hari Dandapani, Amrita Dosanjh","doi":"10.2147/PHMT.S513904","DOIUrl":"10.2147/PHMT.S513904","url":null,"abstract":"<p><strong>Purpose: </strong>The prevalence of pulmonary nontuberculous mycobacteria (NTM) infection and disease is increasing globally. Pediatric studies on treatment of pulmonary NTM disease in immunocompetent infants are limited, and adult guidelines lack details regarding age-specific management strategies. This systematic review analyzes pharmaceutical, procedural, and supportive management strategies for pulmonary NTM infections in immunocompetent infants based on published case reports and series.</p><p><strong>Methods: </strong>A systematic review of PubMed for case reports on pulmonary NTM infections in immunocompetent infants (≤24 months) until December 2023 was conducted. Demographic information, therapeutic interventions, procedural details, and patient outcomes were extracted to Covidence. Data on therapeutic strategies were summarized descriptively.</p><p><strong>Results: </strong>Twenty-six case reports describing 33 infants with pulmonary NTM were identified. Study demographics included: 55% female, median age at diagnosis was 12 months, and <i>Mycobacterium avium</i> complex (58%) was the most common NTM strain. Most patients (94%) received antibiotic therapy, with a median treatment duration of 30 weeks. Common regimens included combined ethambutol with rifampin (n=9) or clarithromycin (n=6), and clarithromycin with amikacin (n=6). Most patients started on therapy for tuberculosis before switching treatment courses after NTM diagnosis. Common antibiotic classes after NTM diagnosis were macrolides, antituberculous, and aminoglycosides. Non-pharmaceutical therapies included 79% undergoing diagnostic bronchoscopy, 39% receiving tissue debulking, 33% undergoing surgical biopsy for diagnostic confirmation, and 12% requiring lung resection. Two patients underwent surgical interventions without antibiotics. Supportive therapies included non-invasive supplemental oxygen (12%) and mechanical ventilation (6%), with three patients admitted to intensive care units. Overall survival rate was 94%.</p><p><strong>Conclusion: </strong>This study reports diverse therapeutic approaches to management of immunocompetent infants with diagnosed pulmonary NTM disease, which utilized varying antibiotics and procedural interventions. Although few patient deaths were reported, these results suggest a need for additional prospective studies to compare efficacy of treatment regimens and establish tailored pediatric guidelines for disease management.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"171-182"},"PeriodicalIF":1.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regional Disparities and Maternal Sociodemographic Determinants of Full Immunization Coverage Among Children Aged 12-23 Months in Nigeria: Insights from NDHS 2018. 尼日利亚12-23个月儿童免疫完全覆盖的区域差异和孕产妇社会人口统计学决定因素:来自2018年国家人口与健康调查的见解。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-07-08 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S520721
Jamilu Sani, Salad Halane, Mohamed Mustaf Ahmed, Abdiwali Mohamed Ahmed, Mohamed Dahir Hersi
{"title":"Regional Disparities and Maternal Sociodemographic Determinants of Full Immunization Coverage Among Children Aged 12-23 Months in Nigeria: Insights from NDHS 2018.","authors":"Jamilu Sani, Salad Halane, Mohamed Mustaf Ahmed, Abdiwali Mohamed Ahmed, Mohamed Dahir Hersi","doi":"10.2147/PHMT.S520721","DOIUrl":"10.2147/PHMT.S520721","url":null,"abstract":"<p><strong>Background: </strong>Childhood immunization is crucial for reducing morbidity and mortality from vaccine-preventable diseases. Despite global efforts, Nigeria faces persistently low immunization uptake with significant regional and socioeconomic disparities. This study investigated the prevalence, regional disparities, and sociodemographic determinants of full immunization coverage among children aged 12-23 months in Nigeria.</p><p><strong>Methods: </strong>This secondary analysis utilized data from the 2018 Nigeria Demographic and Health Survey (NDHS), focusing on 2453 mothers with children aged 12-23 months. Full immunization coverage was defined per World Health Organization (WHO) guidelines. Descriptive statistics, bivariate analysis, and multivariable logistic regression identified predictors of coverage.</p><p><strong>Results: </strong>Only 26% of children were fully immunized nationwide. Marked regional disparities were observed, with the North West (13%) and North East (18%) exhibiting the lowest rates, while the South East (42%) and South South (41%) had the highest. Multivariable analysis revealed that maternal education, household wealth, and region of residence were significant predictors. Children of mothers with higher education were more likely to be fully immunized (AOR: 1.87, 95% CI: 1.10-3.18, p = 0.022), as were those from the richest households compared to the poorest (AOR: 3.20, 95% CI: 1.95-5.25, p < 0.001). Children in the South East (AOR: 2.00, 95% CI: 1.16-3.46, p = 0.013) and South South (AOR: 1.73, 95% CI: 0.99-3.02, p = 0.052) also showed significantly higher odds of full immunization compared to the North West.</p><p><strong>Conclusion: </strong>Full immunization coverage in Nigeria remains critically low, driven by pronounced regional and socioeconomic inequities. Targeted interventions focusing on improving maternal education, expanding equitable healthcare access in underserved regions, and providing financial support to low-income families are essential. Policy efforts must prioritize these vulnerable groups to enhance child health outcomes and achieve universal immunization coverage in Nigeria.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"157-170"},"PeriodicalIF":1.7,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated Diffuse Splenic Hemangiomatosis Arising in an Adolescent: A Rare Case Report and Literature Review. 青少年孤立性弥漫性脾血管瘤病1例报告及文献复习。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-06-28 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S516902
Zhuping Chen, Dongdong Zhang
{"title":"Isolated Diffuse Splenic Hemangiomatosis Arising in an Adolescent: A Rare Case Report and Literature Review.","authors":"Zhuping Chen, Dongdong Zhang","doi":"10.2147/PHMT.S516902","DOIUrl":"10.2147/PHMT.S516902","url":null,"abstract":"<p><strong>Background: </strong>Diffuse splenic hemangiomatosis (DSH) is an extremely rare benign vascular disorder characterized by the proliferation of multiple blood vessels within the spleen. It is even rarer in pediatric and adolescent patients, with only a few cases reported in medical literature, which was performed as scientific literature review.</p><p><strong>Case presentation: </strong>We observed a 14-year-old male who presented with intermittent abdominal discomfort and slight splenomegaly. Laboratory tests revealed no abnormalities. Computed tomography (CT) revealed diffuse splenomegaly with round or oval low-density lesions, suggestive of hemangiomatosis or lymphoma. Magnetic resonance imaging (MRI) revealed multiple lesions with slightly prolonged T1 and T2 signals. A CT-guided percutaneous biopsy of a splenic lesion was performed to address splenomegaly and diagnostic uncertainty. Histopathological examination confirmed diffuse splenic hemangiomatosis with lymphocytic infiltration.</p><p><strong>Conclusion: </strong>A rare case of DSH in a childhood was presented. This case underscores the importance of integrating imaging and histopathology for an accurate diagnosis. While the condition is typically benign, tissue biopsy remains the definitive diagnostic method when malignancy cannot be excluded.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"149-155"},"PeriodicalIF":1.7,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12219155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence and Associated Risk Factors of Neonatal Developmental Dysplasia of the Hip in Saudi Arabia: A Retrospective Cohort Study. 沙特阿拉伯新生儿髋关节发育不良的发生率及相关危险因素:一项回顾性队列研究。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-06-17 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S506196
Jamal Sayed, Ihdaa Jamal Abdulwahab, Banan Bakheet Aldaadi, Ayman Eltahan, Noha Ahmed Alzahrani, Abdullah Jameel Aburiziza, Ghaida Ali Mubarak Alzahrani
{"title":"Incidence and Associated Risk Factors of Neonatal Developmental Dysplasia of the Hip in Saudi Arabia: A Retrospective Cohort Study.","authors":"Jamal Sayed, Ihdaa Jamal Abdulwahab, Banan Bakheet Aldaadi, Ayman Eltahan, Noha Ahmed Alzahrani, Abdullah Jameel Aburiziza, Ghaida Ali Mubarak Alzahrani","doi":"10.2147/PHMT.S506196","DOIUrl":"10.2147/PHMT.S506196","url":null,"abstract":"<p><strong>Purpose: </strong>Developmental dysplasia of the hip (DDH) is a malformation of the hip joint that can lead to subluxation or dislocation. Early diagnosis is crucial for effective non-surgical management. The reported prevalence of DDH varies across studies.</p><p><strong>Objective: </strong>To determine the cumulative incidence of DDH based on clinical examination and diagnostic ultrasonography and to identify associated risk factors.</p><p><strong>Patients and methods: </strong>Between January 2020 and June 2023, 279 ultrasound studies were retrieved from the Security Forces Hospital in Makkah, Saudi Arabia. From the patients' files, we identified risk factors for DDH, including prematurity, gender, breech presentation, mode of delivery, and family history using the Chi-square test and odds ratios (OR).</p><p><strong>Results: </strong>After excluding two cases with chromosomal abnormalities, the final cohort included 277 neonates (60.6% female) and 39.4% males. A positive family history was present in 5%, and 31.5% had a breech presentation. The Ortolani and Barlow tests indicated a DDH incidence of 8.05 per 1000 live births, while selective ultrasound confirmed an incidence of 2.13 per 1000 live births. Prematurity was significantly associated with DDH (P = 0.046), and breech presentation increased the risk approximately fourfold, OR = 3.95, P = 0.016.</p><p><strong>Conclusion: </strong>DDH incidence in Makkah aligns with global averages. Prematurity significantly increases DDH risk, and breech presentation increases the risk by approximately four times.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"139-147"},"PeriodicalIF":1.7,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12182238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Pediatric Cardiopulmonary Resuscitation: A Retrospective Cross-Sectional Study from a Single Center. 儿童心肺复苏的结果:来自单一中心的回顾性横断面研究。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-06-04 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S518499
Rola S Saqan, Liqaa A Raffee, Khaled J Zaitoun, Ghena Zaitoun, Salam Omar Tahtamoni, Khaled Zayed Alawneh, Retaj K Alawneh, Murad A Yasawy, Rami AlAzab
{"title":"Outcomes of Pediatric Cardiopulmonary Resuscitation: A Retrospective Cross-Sectional Study from a Single Center.","authors":"Rola S Saqan, Liqaa A Raffee, Khaled J Zaitoun, Ghena Zaitoun, Salam Omar Tahtamoni, Khaled Zayed Alawneh, Retaj K Alawneh, Murad A Yasawy, Rami AlAzab","doi":"10.2147/PHMT.S518499","DOIUrl":"10.2147/PHMT.S518499","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiac arrest is defined by a lack of central pulse, unresponsiveness, and apnea, indicating the termination of effective mechanical heart activity. Although rare in pediatrics, it results in poor outcomes. Results concerning the survival rates of pediatrics after cardiopulmonary resuscitation (CPR) in Jordan are absent, making this study crucial knowledge for implication of hospital protocol.</p><p><strong>Material/method: </strong>A retrospective study was conducted at a tertiary hospital in Jordan. This study included 411 pediatric patients, aged over one day to under 12 years, who underwent CPR either during an emergency department (ED) visit or during hospitalization. The Mann-Whitney <i>U</i>-test, Chi-Square test, and Fisher's exact tests were used for analysis. Survival-associated factors were analyzed using univariate and multivariate logistic regression, and p < 0.05 was considered significant.</p><p><strong>Results: </strong>Patients were separated into a less than one year age group and a greater than one year age group, with similar gender distributions. Survival was significantly associated with age; the survivors were older than the non-survivors. Furthermore, the presence of any neurological manifestation was associated with a higher risk of mortality with an odds ratio of 3.97 (95% CI: 1.46-10.86, p = 0.007). After adjusting for all covariates, each 1% rise in oxygen saturation increased the adjusted odds ratio (AOR) of survival (AOR = 1.08, 95% CI 1.01-1.15; p = 0.031). In the same model, every additional minute of CPR sharply decreased the likelihood of survival (AOR = 0.38, 95% CI 0.21-0.72; p = 0.003).</p><p><strong>Conclusion: </strong>The survival rates after CPR in pediatrics were poor overall, suggesting a need for better pediatric CPR strategies and further studies. Many factors could affect the outcomes, most importantly, the duration of CPR and the oxygen saturation.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"129-137"},"PeriodicalIF":1.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12146883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Multi-Center Survey of Necrotizing Enterocolitis Prevention Strategies in Very Low Birth Weight Infants. 极低出生体重儿坏死性小肠结肠炎预防策略的多中心调查。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-05-21 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S509863
Xiaoshan Hu, Miao Qian, Wenjuan Chen, Shushu Li, Xiaohui Chen, Shuping Han
{"title":"A Multi-Center Survey of Necrotizing Enterocolitis Prevention Strategies in Very Low Birth Weight Infants.","authors":"Xiaoshan Hu, Miao Qian, Wenjuan Chen, Shushu Li, Xiaohui Chen, Shuping Han","doi":"10.2147/PHMT.S509863","DOIUrl":"10.2147/PHMT.S509863","url":null,"abstract":"<p><strong>Objective: </strong>To compare the prevention practices of necrotizing enterocolitis (NEC) across 17 neonatal intensive care units (NICUs) in China.</p><p><strong>Methods: </strong>A web-based survey was sent to 17 level 3 NICUs in China on September 21, 2023, to evaluate the prevention strategies for NEC.</p><p><strong>Results: </strong>All 17 Neonatal Intensive Care Units (NICUs) responded to the survey. There was significant variation in the initial empirical use of antibiotics for early-onset sepsis, late-onset sepsis, and NEC among different NICUs. Out of the 17 NICUs, only 5 (29.4%) used donor human milk. Additionally, 15 (88.2%) NICUs performed routine echocardiography (Echo) in preterm infants after birth to evaluate cardiac function and/or Patent Ductus Arteriosus (PDA) status. Out of those 15 NICUs, 11 (73.3%) performed Echo within 24 to 72 hours after birth. Furthermore, 8 NICUs (47.1%) did not alter enteral nutrition management during drug treatment for PDA, while 12 NICUs (70.6%) stopped 1 or 2 feeds during red blood cell transfusion.</p><p><strong>Conclusion: </strong>The findings of this survey conducted through questionnaires revealed both differences and similarities in the strategies employed to prevent NEC in 17 NICUs in China.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"121-127"},"PeriodicalIF":1.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103866/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of Parental Interaction in Early Childhood: Insights from the 2022 Multiple Indicator Cluster Survey in Thailand. 儿童早期父母互动的决定因素:来自泰国2022年多指标聚类调查的见解。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-05-16 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S516635
Thitikorn Topothai, Napat Phisanbut, Chompoonut Topothai, Rapeepong Suphanchaimat, Viroj Tangcharoensathien
{"title":"Determinants of Parental Interaction in Early Childhood: Insights from the 2022 Multiple Indicator Cluster Survey in Thailand.","authors":"Thitikorn Topothai, Napat Phisanbut, Chompoonut Topothai, Rapeepong Suphanchaimat, Viroj Tangcharoensathien","doi":"10.2147/PHMT.S516635","DOIUrl":"10.2147/PHMT.S516635","url":null,"abstract":"<p><strong>Purpose: </strong>Parental interaction in learning-promoting activities is crucial for supporting early childhood development. This study aimed to assess the level of parental interaction among children aged 2-4 years in Thailand and to identify determinants associated with parental interaction.</p><p><strong>Patients and methods: </strong>A cross-sectional analysis was conducted using data from the 2022 Multiple Indicator Cluster Survey (MICS), which included a nationally representative sample of 7003 parents of children aged 2-4 years. Parental interaction was assessed through six activities promoting early stimulation and responsive care. Interaction levels were categorized as high (participation in four or more activities) or low (fewer than four activities). Multivariable logistic regression was employed to analyze associations between parental interaction levels and household and participant characteristics.</p><p><strong>Results: </strong>The study found that 88.1% of parents reported high levels of interaction with their children. Children outside Bangkok had lower odds of high interaction, particularly in the Central (AOR=0.33), North (AOR=0.31), Northeast (AOR=0.44), and South (AOR=0.38) regions. Higher odds of high interaction were associated with maternal education above secondary level (AOR=2.00), the highest wealth quintile (AOR=2.48), living with either (AOR=2.14) or both parents (AOR=2.59), being in a non-Thai-speaking household (AOR=1.75), and having three or more books at home (AOR=3.63).</p><p><strong>Conclusion: </strong>Nearly 12% of parents reported low levels of interaction with their children aged 2-4 years, with disparities associated with regional and socioeconomic factors. Policy efforts should prioritize integrating parental support into early childhood education programs and enhancing access to resources, such as children's books and community libraries, particularly for socioeconomically disadvantaged groups.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"109-119"},"PeriodicalIF":1.7,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12091233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Fibrinous and Organizing Pneumonia (AFOP) in Children: A Case Report and Literature Review. 儿童急性纤维性和组织性肺炎(AFOP) 1例报告及文献复习。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-04-02 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S501998
Mohammed AlZaid, Ahmed AlEidan, Wajd AlThakfi, Wadha Helal Alotaibi
{"title":"Acute Fibrinous and Organizing Pneumonia (AFOP) in Children: A Case Report and Literature Review.","authors":"Mohammed AlZaid, Ahmed AlEidan, Wajd AlThakfi, Wadha Helal Alotaibi","doi":"10.2147/PHMT.S501998","DOIUrl":"10.2147/PHMT.S501998","url":null,"abstract":"<p><strong>Introduction: </strong>Acute Fibrinous and Organizing Pneumonia (AFOP) is a rare lung disease that presents with acute lung injury characterized by intra-alveolar fibrin deposition. Although primarily described in adults, AFOP can occur in children and may mimic common respiratory illnesses, posing a diagnostic challenge. The condition can result from various etiological factors, including infections, autoimmune disorders, and drug reactions. The purpose of this case is to highlight the clinical presentation, diagnostic challenges and management strategies of this rare and underrecognized pediatric condition. By describing this case we aim to raise awareness among pediatricians given the limited literature on pediatric AFOP to aid in recognizing and tailoring treatment in order to improve outcomes.</p><p><strong>Methods and materials: </strong>Patient's data were collected retrospectively from medical records, including clinical notes, laboratory results, imaging studies, and histopathological findings, where applicable. Informed written consent was obtained and signed from parents of the child for the use of his medical information for educational and publication purposes, ensuring confidentiality and anonymity.</p><p><strong>Results: </strong>We present the case of a 3-year-old boy with a history of recurrent viral-induced wheezing, initially treated for asthma-like symptoms until he developed persistent hypoxemia. Despite targeted therapy, the patient exhibited persistent respiratory symptoms and consolidative opacities in the right lung. A high-resolution computed tomography (HRCT) scan showed diffuse lung abnormalities, prompting further evaluation. Bronchoscopy with bronchoalveolar lavage revealed Haemophilus influenzae infection, and an open lung biopsy confirmed AFOP. The patient was treated with corticosteroids and azithromycin, leading to significant clinical and radiographic improvement.</p><p><strong>Conclusion: </strong>This case highlights the importance of considering AFOP in pediatric patients with atypical and persistent respiratory symptoms. Early diagnosis and intervention are crucial for managing this rare condition. Further case reports are needed to better understand AFOP's clinical course and optimize treatment strategies in pediatric populations.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"103-108"},"PeriodicalIF":1.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11972569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neonatal Mortality and Associated Factors at a Tertiary-Level Neonatal Intensive Care Unit in Mogadishu, Somalia: A Retrospective Study. 索马里摩加迪沙一家三级新生儿重症监护病房的新生儿死亡率及相关因素:回顾性研究。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-03-28 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S500093
Mohamud Eyow Ali, Yusuf Omar Hassan, Mohammed A M Ahmed, Liban Bile Mohamud
{"title":"Neonatal Mortality and Associated Factors at a Tertiary-Level Neonatal Intensive Care Unit in Mogadishu, Somalia: A Retrospective Study.","authors":"Mohamud Eyow Ali, Yusuf Omar Hassan, Mohammed A M Ahmed, Liban Bile Mohamud","doi":"10.2147/PHMT.S500093","DOIUrl":"10.2147/PHMT.S500093","url":null,"abstract":"<p><strong>Background: </strong>Neonatal mortality is a significant global health challenge, particularly in sub-Saharan Africa. In Somalia, there is a notable absence of comprehensive reports or data on neonatal mortality rates within tertiary-level neonatal intensive care units (NICU). This study aims to identify key factors associated with neonatal mortality in Mogadishu, Somalia.</p><p><strong>Materials and methods: </strong>A retrospective review of medical records was conducted for neonates admitted to the Neonatal Intensive Care Unit (NICU) of Mogadishu Somali Turkish Training and Research Hospital from August 2017 to September 2019. Logistic regression analysis was employed using SPSS (version 25) to compute adjusted odds ratios (aORs) along with 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Of 1043 neonates, 63.8% (n=665) were male, with a mean age of 1.48 days. Most neonates were full-term (55.3%, n=577), while 25.8% (n=269) were preterm (<32 weeks), and 11.9% (n=124) were late preterm (33-37 weeks). In total, 25.5% (n=266) had very low birth weight (<1500 grams). The average length of stay in the NICU was 7.38 days, and the overall mortality rate was 18.7% (n=195). Indications for NICU admissions were prematurity 27.0% (n=282), followed by birth asphyxia (18.0%, n=188), neonatal sepsis (14.6%, n=152), and acute respiratory distress syndrome (12.2%, n=127). Preterm neonates had significantly higher mortality rates (OR=2.14, 95% CI: 1.32-3.47, p=0.002), and those with a birth weight of <1500 grams had an even higher risk of mortality (OR=3.85, 95% CI: 2.50-5.92, p<0.001). Lack of ANC visits was associated with increased mortality risk (OR=1.67, 95% CI: 1.09-2.54, p=0.019), while cesarean delivery was also linked to higher mortality risk (OR=1.92, 95% CI: 1.29-2.85, p=0.002).</p><p><strong>Conclusion: </strong>The study identified a Neonatal Mortality Rate that is acceptable compared to the mortality rates in other studies in Somalia and the sub-Saharan African region. These findings inform care strategies and resource allocation in prenatal and neonatal health services.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"93-102"},"PeriodicalIF":1.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11960485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parenting Styles of Divorced Parents and Their Influence on Their Children's Bruxism: A Cross-Sectional Study. 离异父母教养方式对子女磨牙症的影响:一项横断面研究。
IF 1.7
Pediatric health, medicine and therapeutics Pub Date : 2025-03-27 eCollection Date: 2025-01-01 DOI: 10.2147/PHMT.S508109
María Moya-López, Ana Ruiz-Guillén, Martín Romero-Maroto, Bruno Baracco, María Carrillo-Díaz
{"title":"Parenting Styles of Divorced Parents and Their Influence on Their Children's Bruxism: A Cross-Sectional Study.","authors":"María Moya-López, Ana Ruiz-Guillén, Martín Romero-Maroto, Bruno Baracco, María Carrillo-Díaz","doi":"10.2147/PHMT.S508109","DOIUrl":"10.2147/PHMT.S508109","url":null,"abstract":"<p><strong>Purpose: </strong>Parental divorce is one of the most common adverse events in childhood and can cause children emotional problems and influence their oral health. To explore differences in possible bruxism, state anxiety, coping and parenting styles between a group of divorced parents and a group of cohabiting parents.</p><p><strong>Patients and methods: </strong>A cross-sectional study was conducted, with data collected through self-report questionnaires filled in by 186 patients (8-16 years) and their parents. Children completed State Trait Anxiety Inventory (STAI), Self-Report Coping Measure (SRCM) and Parenting Style Scale. The Self-Reported Bruxism Questionnaire (SBQ) was completed by their parents.</p><p><strong>Results: </strong>The results showed significant differences were seen between the group of divorced parents (n=93) and the control group (n=93), with higher levels of state anxiety and possible bruxism in the group of children of divorced parents. In addition, in terms of coping strategies, externalisation and problem-solving deficits stood out. In terms of parenting style, autonomy promotion was higher. Additionally, possible bruxism was influenced by coping strategies (seeking social support), attachment-based parenting style and communication, behavioural control and state anxiety. Finally, it was found that high anxiety may act as a moderating variable in the relationship between divorced parents and possible bruxism.</p><p><strong>Conclusion: </strong>Children of divorced parents showed more possible bruxism, anxiety, coping and behavioural problems.</p>","PeriodicalId":74410,"journal":{"name":"Pediatric health, medicine and therapeutics","volume":"16 ","pages":"83-92"},"PeriodicalIF":1.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11956699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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