Neurology perspectives最新文献_第3页

Impact of COVID-19 on physiotherapy for patients with multiple sclerosis in Spain: Adaptation and challenges in the implementation of telerehabilitation COVID-19对西班牙多发性硬化症患者物理治疗的影响：远程康复实施中的适应和挑战

Neurology perspectives Pub Date : 2025-02-24 DOI: 10.1016/j.neurop.2025.100188

I. Yeregui-Prieto , R. Berriozabalgoitia Etxaniz , N. Martínez Lerín , G. Yaya-Tur , G. Loyola , E.R. Meza-Murillo , C. Santoyo-Medina

{"title":"Impact of COVID-19 on physiotherapy for patients with multiple sclerosis in Spain: Adaptation and challenges in the implementation of telerehabilitation","authors":"I. Yeregui-Prieto , R. Berriozabalgoitia Etxaniz , N. Martínez Lerín , G. Yaya-Tur , G. Loyola , E.R. Meza-Murillo , C. Santoyo-Medina","doi":"10.1016/j.neurop.2025.100188","DOIUrl":"10.1016/j.neurop.2025.100188","url":null,"abstract":"<div><h3>Introduction</h3><div>The COVID-19 pandemic, declared in March 2020, had a profound impact on health services in Spain, especially on physiotherapy for people with multiple sclerosis (PwMS). The health reorganization forced the suspension of rehabilitation services, affecting millions of people with disabilities in Europe.</div></div><div><h3>Objective</h3><div>To evaluate the impact of the pandemic on the clinical practice of the Physiotherapy Collective (CF) specialized in multiple sclerosis (MS) in Spain, highlighting the changes in interventions and the use of telerehabilitation (TRHB).</div></div><div><h3>Materials and methods</h3><div>An international survey was designed and disseminated in Spain through MS associations. The sample included 32 physiotherapists. The statistical analysis was performed with IBM SPSS, with a significance level of <em>p</em> ≤ 0.05.</div></div><div><h3>Results</h3><div>A total of 78% of physiotherapists worked with PwMS before the pandemic, and the use of TRHB increased to 29.24%. A reduction in face-to-face interventions, especially in manual therapies, was observed, mainly affecting patients with severely impaired mobility (SIM). However, 81.3% kept aerobic training sessions online. The main barriers were the lack of devices and the difficulty in conducting adequate assessments.</div></div><div><h3>Conclusions</h3><div>The pandemic not only underscored the importance of TRHB but also exposed key limitations. Future research should focus on improving its feasibility and providing appropriate training to optimize care for PwMS.</div></div>","PeriodicalId":74283,"journal":{"name":"Neurology perspectives","volume":"5 2","pages":"Article 100188"},"PeriodicalIF":0.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guillain-Barré syndrome following acute hepatitis E virus infection: A novel Indian case report with acute inflammatory demyelinating polyneuropathy pattern and anti-GM1 antibodies 急性戊型肝炎病毒感染后的格林-巴利综合征：印度一例急性炎症性脱髓鞘多神经病变模式和抗gm1抗体的新病例报告

Neurology perspectives Pub Date : 2025-02-24 DOI: 10.1016/j.neurop.2025.100187

R. Ghosh , M. León-Ruiz , A.S. Mondal , S. Dubey , J. Benito-León

引用次数: 0

Adult-onset cerebral X-linked adrenoleukodystrophy presenting with frontal lobe syndrome caused by a de novo ABCD1 gene mutation (c.1415_1416delAG, p.Gln472fs*83) ABCD1基因突变引起的成人脑x连锁肾上腺脑白质营养不良伴额叶综合征（c.1415_1416delAG, p.Gln472fs*83）

Neurology perspectives Pub Date : 2025-02-24 DOI: 10.1016/j.neurop.2025.100186

R. Ghosh , M. León-Ruiz , A. Jana , S. Dubey , J. Benito-León

引用次数: 0

Stroke machine learning for discharge planning: A pilot implementation study 用于出院规划的脑卒中机器学习：试点实施研究

Neurology perspectives Pub Date : 2025-01-30 DOI: 10.1016/j.neurop.2025.100183

S. Bacchi , R. Goh , J. Kovoor , S. Gluck , L. Oakden-Rayner , S. Koblar , T. Kleinig , J. Jannes

引用次数: 0

Late-onset myoclonic epilepsy in Down syndrome (LOMEDS) and efficacy of perampanel 唐氏综合征迟发性肌阵挛性癫痫（LOMEDS）和perampanel的疗效

Neurology perspectives Pub Date : 2025-01-30 DOI: 10.1016/j.neurop.2025.100184

Nazaret Peláez Vina , D.D. Bórquez , E.N. Moral , M. Cáceres

引用次数: 0

Ibero-American consensus statement on migraine treatment 伊比利亚-美洲偏头痛治疗共识声明

Neurology perspectives Pub Date : 2025-01-01 DOI: 10.1016/j.neurop.2024.100182

José Miguel Láinez , Oscar Pradilla , Pablo Irimia , Fidel Sobrino , Michel Volcy , Pedro Kowaks , Ildefonso Rodríguez Leyva , Fiorella Martín , Lucía Zavala , Alex Espinoza

{"title":"Ibero-American consensus statement on migraine treatment","authors":"José Miguel Láinez , Oscar Pradilla , Pablo Irimia , Fidel Sobrino , Michel Volcy , Pedro Kowaks , Ildefonso Rodríguez Leyva , Fiorella Martín , Lucía Zavala , Alex Espinoza","doi":"10.1016/j.neurop.2024.100182","DOIUrl":"10.1016/j.neurop.2024.100182","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Migraine is the most common reason for neurology outpatient consultation; more than 80% of patients with migraine suffer some degree of associated disability. Migraine is an underdiagnosed disorder and patients frequently receive inappropriate treatment, which is why it is necessary to establish recommendations to improve patient management. The objective of this document is to establish a consensus position on the pharmacological treatment of migraine, including general measures and detailed analysis of the different options for the treatment of attacks and their prevention, from the perspective of Ibero-American countries.</div></div><div><h3>Methods and results</h3><div>Based on the recommendation documents published by the scientific societies of different Ibero-American countries, 2 surveys were prepared; through the application of the Delphi methodology and discussions in subsequent meetings, a document was developed in consensus format, supported by evidence from the literature and expert recommendations.</div></div><div><h3>Conclusions</h3><div>A series of recommendations were agreed upon for the treatment of episodic migraine and chronic migraine, both for the acute management of attacks and for their prevention. These recommendations are based on the consensus process and a literature review, and are adapted to the regional conditions of the Ibero-American countries.</div></div>","PeriodicalId":74283,"journal":{"name":"Neurology perspectives","volume":"5 1","pages":"Article 100182"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143133576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survey on first-line therapeutic management of relapsing–remitting multiple sclerosis in clinical practice in Spain 西班牙临床实践中复发-缓解型多发性硬化症一线治疗管理的调查

Neurology perspectives Pub Date : 2025-01-01 DOI: 10.1016/j.neurop.2024.100178

M. Llaneza , G. Fontes , L. Benedito-Palos , E. Moral

{"title":"Survey on first-line therapeutic management of relapsing–remitting multiple sclerosis in clinical practice in Spain","authors":"M. Llaneza , G. Fontes , L. Benedito-Palos , E. Moral","doi":"10.1016/j.neurop.2024.100178","DOIUrl":"10.1016/j.neurop.2024.100178","url":null,"abstract":"<div><h3>Introduction</h3><div>Current therapies for relapsing–remitting multiple sclerosis (RRMS) help reduce morbidity and delay disease progression. However, the available information on factors influencing decision-making regarding first-line treatment remain poorly understood.</div></div><div><h3>Methods</h3><div>Based on a review of the literature and the experience of a scientific committee made up by 2 neurologists, an ad hoc survey was developed and distributed to Spanish neurologists. It included 22 questions related to the first-line therapeutic management of RRMS.</div></div><div><h3>Results</h3><div>Sixty neurologists (mean age: 45.6 years, 60% women, mean of 16.0 years of experience, mean of 93.8 patients with RRMS attended/month) participated in the study. Neurologists considered that the 3 most important treatment characteristics (1–8 points, with higher scores denoting greater relevance) in treatment decision-making were efficacy in disease control (7.8±0.5), safety/tolerability (6.7±0.9), and improvements in patient quality of life (5.0±1.5); regarding patient characteristics, the 3 most important (1–7 points) were disease activity (6.9±0.5), intention to become pregnant (5.0±1.0), and level of disability (4.3±1.8). Dimethyl fumarate (32.6%) was the most frequently prescribed treatment, followed by teriflunomide (24.8%) and glatiramer acetate (17.6%). According to over 87% of the specialists, the latter drug was considered the most appropriate treatment for patients with liver disorders, who intended to become pregnant, and who presented low disease activity.</div></div><div><h3>Conclusions</h3><div>Our study provides evidence on the first-line therapeutic management of non-aggressive forms of RRMS and the factors influencing decision-making in routine clinical practice.</div></div>","PeriodicalId":74283,"journal":{"name":"Neurology perspectives","volume":"5 1","pages":"Article 100178"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143133607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

20886. EFECTIVIDAD DEL TRATAMIENTO CON TOXINA BOTULÍNICA Y ANTICUERPOS MONOCLONALES ANTI-CGRP EN LA MIGRAÑA ASOCIADA A LA MENSTRUACIÓN 20886. 用肉毒杆菌毒素和单克隆抗cgrp药物治疗与培训有关的移民的效果

Neurology perspectives Pub Date : 2024-11-01 DOI: 10.1016/S2667-0496(24)00052-8

L. Gómez Dabó, R. Mas de les Valls, V. Gallardo Gómez-Dabó, A. Alpuente, M. Torres Ferrús, E. Caronna, E. Giné Ciprés, P. Pozo Rosich

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21619. PATRONES DE METABOLISMO CEREBRAL EN EL CONTINUUM DE LA ENFERMEDAD DE ALZHEIMER EN EL SÍNDROME DE DOWN 21619. 阿尔茨海默氏症在唐氏综合症连续体中的脑部代谢模式

Neurology perspectives Pub Date : 2024-11-01 DOI: 10.1016/S2667-0496(24)00079-6

J. Arriola Infante, A. Morcillo Nieto, S. Zsadanyi, M. Franquesa Mullerat, L. Vaqué Alcázar, M. Rozalem Aranha, J. Arranz Martínez, Í. Rodríguez Baz, L. Maure Blesa, L. Videla Toro, I. Barroeta Espar, L. del Hoyo Soriano, B. Benejam, S. Fernández González, A. Sanjuán Hernández, N. Zhu, J. García Castro, S. Rubio Guerra, E. Vera Campuzano, J. Selma González, A. Bejanin

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21071. UTILIDAD DE LA DETERMINACIÓN DE PROADRENOMODULINA EN EL CÓDIGO ICTUS: ESTUDIO PRESTO 21071. 确定proadrenomodulin在现行法典中的作用：本研究

Neurology perspectives Pub Date : 2024-11-01 DOI: 10.1016/S2667-0496(24)00138-8

C. Sanabria Gago, R. Berbegal Serralta, J. Alonso Maroto, V. Escribano Hernández, B. Colino Galián, E. Salgado Barbado, M. Sobrado Sanz, C. Ramos Marín, Á. Ximénez-Carrillo Rico, E. de la Fuente Sanz, A. González Martínez, C. Sánchez Rodríguez, A. Somovillla, J. Vivancos Mora, S. Trillo Senín

引用次数: 0