Autoimmune eye diseases in multiple sclerosis

M.L. Martínez Ginés , P. Rojas Lozano
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Abstract

Introduction

The eye is a complex organ that can present complications related to autoimmune diseases, including multiple sclerosis (MS). Ocular manifestations may act as early indicators of autoimmune diseases, and their early diagnosis and treatment are essential to guaranteeing patients' quality of life. This review analyses the main autoimmune eye diseases associated with MS, focusing on intermediate uveitis and its personalised management.

Development

MS-associated uveitis includes various forms of intraocular inflammation affecting different areas of the eye. The relationship between MS and uveitis is complex and involves shared immunological mechanisms and diagnostic and therapeutic challenges. The clinical presentation of uveitis varies from asymptomatic forms to severe vision-threatening complications. The treatment of uveitis involves careful assessment and the consideration of immunomodulatory or immunosuppressive treatment with a view to controlling inflammation and preventing visual sequelae.

Conclusions

Treatment of MS-related uveitis is complex and requires a multidisciplinary approach. Advances in immunomodulatory therapy offer new treatment options, as well as challenges related to adverse reactions and disease management. Further research is needed to better understand the relationship between MS and eye diseases, and to optimise therapeutic strategies and improve patients' visual and neurological outcomes.
多发性硬化症中的自身免疫性眼病
眼睛是一个复杂的器官,可出现与自身免疫性疾病相关的并发症,包括多发性硬化症(MS)。眼部表现可能是自身免疫性疾病的早期指标,其早期诊断和治疗对于保证患者的生活质量至关重要。这篇综述分析了与MS相关的主要自身免疫性眼病,重点是中度葡萄膜炎及其个体化治疗。ms相关的葡萄膜炎包括影响眼睛不同区域的各种形式的眼内炎症。MS和葡萄膜炎之间的关系是复杂的,涉及共同的免疫机制和诊断和治疗挑战。葡萄膜炎的临床表现从无症状到严重的视力威胁并发症不等。葡萄膜炎的治疗包括仔细评估和考虑免疫调节或免疫抑制治疗,以控制炎症和预防视觉后遗症。结论多发性硬化相关性葡萄膜炎的治疗较为复杂,需要多学科联合治疗。免疫调节疗法的进展提供了新的治疗选择,以及与不良反应和疾病管理相关的挑战。需要进一步的研究来更好地了解MS与眼病之间的关系,并优化治疗策略,改善患者的视觉和神经预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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