Korean journal of clinical oncology最新文献

Pre- and post-radiotherapy assessment of psychosocial factors in female cancer patients and their caregivers: a clinical observational study from India. 女性癌症患者及其护理人员放疗前后心理社会因素评估：来自印度的一项临床观察性研究

Korean journal of clinical oncology Pub Date : 2026-04-01 Epub Date: 2026-04-30 DOI: 10.14216/kjco.25353

Tahreem Arshad, Samreen Zaheer, Mohammad Akram, Deoshree Akhouri, Afreen Kamal Arooqui, Ruquiya Afrose, Shahid Ali Siddiqui

{"title":"Pre- and post-radiotherapy assessment of psychosocial factors in female cancer patients and their caregivers: a clinical observational study from India.","authors":"Tahreem Arshad, Samreen Zaheer, Mohammad Akram, Deoshree Akhouri, Afreen Kamal Arooqui, Ruquiya Afrose, Shahid Ali Siddiqui","doi":"10.14216/kjco.25353","DOIUrl":"https://doi.org/10.14216/kjco.25353","url":null,"abstract":"Purpose: The present study investigates the psychological factors impacting female cancer patients receiving radiotherapy and the individuals providing care for them, within a sociocultural environment that frequently marginalizes and depends on women. This research highlights a strategy for cancer care that may enhance results for both patients and caregivers by attending to psychosocial needs. The primary objectives are to measure the levels of anxiety, depression, quality of life, and perceived stress in both patients and caregivers, as well as to determine how psychosocial counseling affects these factors.Methods: It was a single-group pre-post observational study. Before starting radiotherapy, assessment of various psychosocial factors was done in female cancer patients and their respective caregivers. Psychosocial counseling sessions were conducted at weekly intervals during radiotherapy. At the 6th week after radiotherapy, assessment of same psychosocial factors was done again in both the patients as well as their caregivers.Results: The results show that both patients and caregivers had serious psychological disorders, such as anxiety, depression, perceived stress, and decreased quality of life. Psychosocial modulation was associated with improvement in quality of life measures like overall health and emotional and physical functioning.Conclusion: The findings highlight how crucial it is to include psychological support in radiotherapy regimens. Despite limitations of the study, such as its exclusive focus on female patients, the results highlight the need to provide clinical staff with psycho-oncological training. The study recommends further investigation to ascertain the long-term effects of psychological health on treatment compliance and patient survival.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"22 1","pages":"8-17"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Follow-up for patients with extremity soft tissue sarcoma: validation of a rational schedule. 肢体软组织肉瘤患者的随访：合理计划的验证。

Korean journal of clinical oncology Pub Date : 2026-04-01 Epub Date: 2026-04-30 DOI: 10.14216/kjco.25379

Maroun Rizkallah, Jasson Arcinue, Ahmed Aoude, Robert Turcotte

{"title":"Follow-up for patients with extremity soft tissue sarcoma: validation of a rational schedule.","authors":"Maroun Rizkallah, Jasson Arcinue, Ahmed Aoude, Robert Turcotte","doi":"10.14216/kjco.25379","DOIUrl":"https://doi.org/10.14216/kjco.25379","url":null,"abstract":"Purpose: Patients with soft tissue sarcomas (STS) of the extremity require ongoing follow-up to detect treatment failures. There is a significant variation in follow-up schemes among sarcoma specialists due to a lack of evidence.Methods: A retrospective single-center review was performed on all patients with a minimum 1-year follow-up after resection of a localized STS, utilizing a prospectively collected database. Kaplan-Meier curves were used to calculate the incidence of local recurrence and metastases on an annual basis over 10 years.Results: There were 407 patients who met the inclusion criteria. Considering the annual incidence of local recurrence and distant metastasis per STS size and grade, patients with small, low-grade STS should be followed yearly for 10 years. Patients with small, intermediate/high-grade STS and those with large, low-grade STS should be followed every 6 months for the first 2 years and then yearly until 10 years postoperatively. Patients with large, intermediate/high-grade STS should be followed every 3 months for the first 2 years and then every 6 months thereafter until 10 years postoperatively.Conclusion: Compared to National Comprehensive Cancer Network (NCCN) and European Society for Medical Oncology (ESMO) guidelines, our proposed scheme has the potential to reduce hospital visits, mainly for patients with small intermediate and high-grade tumors. This protocol validates the previously published scheme, despite being relatively more conservative.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"22 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk stratification for malignant upgrade in breast atypical hyperplasia: a Korean multi-institutional analysis from academic hospitals. 乳腺不典型增生恶性升级的风险分层：来自韩国多机构的学术医院分析。

Korean journal of clinical oncology Pub Date : 2026-04-01 Epub Date: 2026-04-30 DOI: 10.14216/kjco.25363

Hyobin Kim, Jung Ho Park, Min Kyoon Kim, Chihwan Cha, Hocheol Lee, Se Jeong Oh, Hoon Choi, Jae Pak Yi, Su Hyun Lim, Eun Young Kim, Young-Joon Kang

{"title":"Risk stratification for malignant upgrade in breast atypical hyperplasia: a Korean multi-institutional analysis from academic hospitals.","authors":"Hyobin Kim, Jung Ho Park, Min Kyoon Kim, Chihwan Cha, Hocheol Lee, Se Jeong Oh, Hoon Choi, Jae Pak Yi, Su Hyun Lim, Eun Young Kim, Young-Joon Kang","doi":"10.14216/kjco.25363","DOIUrl":"https://doi.org/10.14216/kjco.25363","url":null,"abstract":"Purpose: Atypical hyperplasia (AH) management remains controversial due to variable malignant disease progression rates. While Western studies report 10% to 25% upgrade rates, data from Asian populations, particularly from referral academic centers, are limited. We aimed to identify predictive factors for malignant upgrade in Korean women with AH at academic hospitals.Methods: This retrospective multi-institutional study analyzed 340 patients diagnosed with AH on initial biopsy who underwent subsequent excision at five Korean academic hospitals from 2000 to 2022. Malignant upgrade was defined as ductal carcinoma in situ or invasive cancer on the final pathology. Multivariate logistic regression was used to identify independent predictors of upgrades.Results: Among 340 patients (319 atypical ductal hyperplasia, 20 atypical lobular hyperplasia, and 1 mixed), 128 (37.6%) experienced a malignant upgrade, 98 (76.6%) to ductal carcinoma in situ, and 30 (23.4%) to invasive cancer. In multivariate analysis, multifocal atypia (odds ratio [OR], 25.61; 95% confidence interval [CI], 11.20-58.55; P<0.001) and Breast Imaging-Reporting and Data System 4c-5 lesions (OR, 11.02; 95% CI, 1.43-84.86; P=0.021) were significant predictors. Multifocal atypia showed an 84.4% upgrade rate. Core needle biopsy had higher upgrade rates than vacuum-assisted biopsy (45.2% vs. 20.0%; P<0.001). The upgrade rates decreased from 50% to 25% over the study period (P<0.05).Conclusion: The 37.6% upgrade rate in this tertiary referral cohort exceeded that in Western reports, with multifocal atypia emerging as the strongest predictor. These findings support immediate excision for multifocal atypia while allowing individualized management for unifocal lesions with favorable imaging in Korean tertiary care settings.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"22 1","pages":"18-27"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolated IgG4-related cholecystitis mimicking locally advanced gallbladder cancer: a case report. 孤立的igg4相关胆囊炎模拟局部晚期胆囊癌1例报告

Korean journal of clinical oncology Pub Date : 2026-04-01 Epub Date: 2026-04-30 DOI: 10.14216/kjco.26385

Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Myeong Hun Oh

{"title":"Isolated IgG4-related cholecystitis mimicking locally advanced gallbladder cancer: a case report.","authors":"Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Myeong Hun Oh","doi":"10.14216/kjco.26385","DOIUrl":"https://doi.org/10.14216/kjco.26385","url":null,"abstract":"Immunoglobulin G4 (IgG4)-related disease is a fibroinflammatory condition that can involve multiple organs. Isolated involvement of the gallbladder is exceptionally uncommon and often radiologically indistinguishable from gallbladder carcinoma, resulting in diagnostic uncertainty before surgery. A 77-year-old man presented with right upper abdominal discomfort lasting 1 month. Cross-sectional imaging revealed irregular gallbladder wall thickening with contrast enhancement, raising suspicion for resectable gallbladder cancer. The patient underwent a radical cholecystectomy with partial hepatectomy. Histopathological analysis demonstrated dense lymphoplasmacytic infiltration, storiform fibrosis, and marked infiltration of IgG4-positive plasma cells exceeding established diagnostic thresholds, consistent with IgG4-related cholecystitis. The postoperative course was uneventful, and no additional treatment was required. IgG4-related cholecystitis should be considered in the differential diagnosis of gallbladder malignancy, particularly in atypical or indeterminate cases. However, when imaging findings strongly suggest carcinoma, radical surgical resection remains an appropriate oncologic approach.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"22 1","pages":"28-32"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammatory myofibroblastic tumor on second portion of duodenum: a case report. 十二指肠第二段炎性肌成纤维细胞瘤1例。

Korean journal of clinical oncology Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.14216/kjco.25374

Myeong Hun Oh, Hyung Il Seo, Kyung Un Choi, Seung Baek Hong, Young Mok Park, Byeong Gwan Noh, Su Bin Song

{"title":"Inflammatory myofibroblastic tumor on second portion of duodenum: a case report.","authors":"Myeong Hun Oh, Hyung Il Seo, Kyung Un Choi, Seung Baek Hong, Young Mok Park, Byeong Gwan Noh, Su Bin Song","doi":"10.14216/kjco.25374","DOIUrl":"10.14216/kjco.25374","url":null,"abstract":"Inflammatory myofibroblastic tumors (IMTs) of the duodenum are exceptionally uncommon, and their epidemiologic and clinical characteristics remain poorly defined because of the limited number of reported cases. We previously reported a case of duodenal IMT in the Korean Journal of Gastroenterology in 2018, with follow-up data available only up to 12 months. IMTs typically behave in a benign manner, but they may occasionally demonstrate local invasiveness and recurrence; therefore, achieving complete surgical excision is crucial, followed by long-term surveillance. In the present manuscript, we provide a subsequent long-term follow-up report of the same patient, offering an extended 88-month postoperative course and additional radiologic and pathologic details not included in the earlier publication. This follow-up report highlights the long-term benign behavior of the tumor despite positive surgical margins and anaplastic lymphoma kinase (ALK)-negative immunohistochemistry, contributing meaningful information to the scarce literature on adult duodenal IMTs.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"21 3","pages":"159-163"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Ewing sarcoma of the uterine cervix: a case report and comprehensive review. 宫颈原发性尤文氏肉瘤1例报告并综合复习。

Korean journal of clinical oncology Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.14216/kjco.25373

Suday Halder, Seema Singhal, Sandeep Mathur, Sameer Bakhshi, Rambha Pandey, Vidushi Kulshrestha, Ekta Dhamija, Neena Malhotra

{"title":"Primary Ewing sarcoma of the uterine cervix: a case report and comprehensive review.","authors":"Suday Halder, Seema Singhal, Sandeep Mathur, Sameer Bakhshi, Rambha Pandey, Vidushi Kulshrestha, Ekta Dhamija, Neena Malhotra","doi":"10.14216/kjco.25373","DOIUrl":"10.14216/kjco.25373","url":null,"abstract":"Primary Ewing sarcoma of the uterine cervix is an exceptionally rare and aggressive malignancy, with only 34 cases reported in the literature. Early recognition and prompt multimodal treatment are essential due to its poor prognosis. We report a case involving a 32-year-old multiparous woman who presented with foul-smelling vaginal discharge and irregular bleeding. Clinical examination revealed a 6×6 cm friable cervical mass extending into the upper vagina. Imaging demonstrated an FDG-avid cervical mass with regional lymphadenopathy. Histopathological analysis, supported by immunohistochemistry and fluorescence in situ hybridization, confirmed Ewing sarcoma with EWSR1 gene rearrangement. The patient received neoadjuvant chemotherapy with VDC (vincristine, doxorubicin, cyclophosphamide) and PIE (cisplatin, ifosfamide, etoposide) regimens, followed by surgical resection, adjuvant chemotherapy, and pelvic radiotherapy. Although initial disease control was achieved, the patient experienced disease recurrence with distant metastases after a 7-month disease-free interval and succumbed to the illness 9 months after diagnosis. This case underscores the importance of including Ewing sarcoma in the differential diagnosis of rapidly growing cervical tumors, particularly in young women. A multidisciplinary approach involving early molecular diagnostics and aggressive combined therapy is critical to improving clinical outcomes in such rare and aggressive cases.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"21 3","pages":"164-168"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between ovarian and colorectal cancers: a systematic review and meta-analysis. 卵巢癌和结直肠癌之间的关系：系统回顾和荟萃分析。

Korean journal of clinical oncology Pub Date : 2025-12-01 Epub Date: 2025-12-19 DOI: 10.14216/kjco.25355

Heba Ramadan

{"title":"The relationship between ovarian and colorectal cancers: a systematic review and meta-analysis.","authors":"Heba Ramadan","doi":"10.14216/kjco.25355","DOIUrl":"10.14216/kjco.25355","url":null,"abstract":"Purpose: This systematic review and meta-analysis aimed to examine the relationship between ovarian and colorectal cancer, with a particular focus on the standardized incidence ratio (SIR).Methods: A comprehensive search was conducted across multiple databases, including Scopus, Web of Science, PubMed, and Google Scholar. A total of 20 studies were included in the final analysis.Results: The results indicated that women with ovarian cancer had a significantly higher incidence of colorectal cancer (SIR, 1.69; 95% confidence interval [CI], 1.39-1.98), with an increased risk for both colon (SIR, 1.57; 95% CI, 1.14-1.99) and rectal cancers (SIR, 1.58; 95% CI, 1.38-1.78). Subgroup analysis of borderline ovarian tumor revealed an SIR for colorectal cancer of 1.27 (95% CI, 0.99-1.55), with a significant risk in the serous subtype (SIR, 1.38; 95% CI, 1.09-1.67). Conversely, studies examining ovarian cancer in women diagnosed with colorectal cancer showed an SIR of 1.48 (95% CI, 1.17-1.79). Specifically, women with colon cancer had a higher incidence of ovarian cancer (SIR, 1.64; 95% CI, 1.25-2.03), while women with rectal cancer showed a decreased risk (SIR, 0.88; 95% CI, 0.77-0.99). The results underscore the potential bidirectional relationship between ovarian and colorectal cancers, which may be influenced by genetic predispositions.Conclusion: Future advanced genetic studies are needed to better understand the underlying molecular mechanisms. Additionally, the results emphasize the importance of careful cancer surveillance and early detection strategies for women with a history of either ovarian cancer or colorectal cancer.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":" ","pages":"150-158"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145783909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative analysis of endoscopic and nutritional outcomes following distal gastrectomy: Roux-en-Y, uncut Roux-en-Y, and Billroth II with Braun anastomosis. 远端胃切除术Roux-en-Y、未切开Roux-en-Y和Billroth II与Braun吻合后内镜和营养结果的比较分析。

Korean journal of clinical oncology Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.14216/kjco.25364

Tae-Han Kim, Ji-Ho Park, Sang-Ho Jeong, Ra Ri Cha, Hyun Jin Kim, Young-Joon Lee

{"title":"Comparative analysis of endoscopic and nutritional outcomes following distal gastrectomy: Roux-en-Y, uncut Roux-en-Y, and Billroth II with Braun anastomosis.","authors":"Tae-Han Kim, Ji-Ho Park, Sang-Ho Jeong, Ra Ri Cha, Hyun Jin Kim, Young-Joon Lee","doi":"10.14216/kjco.25364","DOIUrl":"10.14216/kjco.25364","url":null,"abstract":"Purpose: This study aimed to compare clinical, nutritional, and endoscopic outcomes among Roux-en-Y (RY), uncut Roux-en-Y (uRY), and Billroth II with Braun anastomosis (BB) reconstruction methods in gastric cancer patients after distal gastrectomy.Methods: This retrospective study analyzed gastric cancer patients who underwent laparoscopic distal gastrectomy between January 2018 and December 2022, categorized into RY, uRY, and BB. Demographic, pathological, clinical, nutritional, and endoscopic data were collected over 24 months. Endoscopic outcomes were assessed using the RGB scoring system, evaluating residual food, gastritis, and bile reflux. Delayed gastric emptying was defined by clinical and imaging criteria. Multivariable linear regression was performed to identify relevant factors associated with 24 months RGB scores and mixed linear model was applied to assess the time interaction.Results: A total of 221 patients were included (70 RY, 75 uRY, 76 BB). Baseline characteristics, perioperative and nutritional outcomes were comparable among groups. The uRY group showed less weight loss at 3 months (5.9%, P<0.05) but did not differ in other studied periods. The RY group had the lowest RGB scores at all time points, while BB showed the highest and progressively worsening scores. Regression model showed that BB and uRY was related to increase 24 month RGB score. BB showed increased RGB score while RY was stable in time and uRY showed intermediate change in the mixed linear model (P<0.05).Conclusion: The nutritional clinical outcomes were comparable between the reconstructions. RY reconstruction demonstrated favorable endoscopic outcomes, while BB was associated with higher RGB scores in time.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"21 3","pages":"121-129"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term survival of gastric cancer patients with positive intraoperative frozen section margins: a single-cohort analysis. 术中冰冻切片边缘阳性胃癌患者的长期生存率：单队列分析。

Korean journal of clinical oncology Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.14216/kjco.25371

Chang-In Choi, Jae-Kyun Park, Tae Yong Jeon, Dae-Hwan Kim

{"title":"Long-term survival of gastric cancer patients with positive intraoperative frozen section margins: a single-cohort analysis.","authors":"Chang-In Choi, Jae-Kyun Park, Tae Yong Jeon, Dae-Hwan Kim","doi":"10.14216/kjco.25371","DOIUrl":"10.14216/kjco.25371","url":null,"abstract":"Purpose: To evaluate clinicopathological characteristics and long-term outcomes of patients with positive resection margins identified during intraoperative frozen section (IFS) in gastric cancer surgery.Methods: A retrospective analysis of 5,894 patients who underwent gastrectomy between May 2005 and December 2023. Among 207 patients with positive IFS margins, 121 were included after exclusion criteria. Additional resection was performed in 87 patients, while 34 received no further resection. Patients were divided into survivor group and non-survivor group for comparison. Patients' demographics, perioperative and survival outcomes were analyzed.Results: R0 resection was achieved in 100 patients (82.6%), while 21 patients (17.4%) had R1 resection. During follow-up, 76 patients survived and 45 died. Five-year overall survival rates were 95.7% for stage I, 56.6% for stage II, and 32.9% for stage III. The non-survivor group showed significantly higher rates of R1 resection (35.6% vs. 6.6%, P<0.001), advanced stage disease (82.2% vs. 40.8%, P<0.001), and pathological high-risk features. In multivariate analysis, TNM stage and R0 resection status were the most significant prognostic factors. Proximal margin length did not correlate with survival outcomes.Conclusion: TNM stage and achieving R0 resection were the most important prognostic factors in patients with positive IFS margins. R0 resection had greater survival impact in low-risk groups, while R1 resection was associated with poor outcomes regardless of stage, emphasizing the importance of complete tumor removal when technically feasible.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"21 3","pages":"130-142"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patients participation in multidisciplinary management in gastric cancer: regulation comparison and expert survey among major countries. 胃癌患者参与多学科管理：主要国家法规比较及专家调查。

Korean journal of clinical oncology Pub Date : 2025-12-01 Epub Date: 2025-12-31 DOI: 10.14216/kjco.25365

Kyoyoung Park, Hyuk-Joon Lee, Seong-Ho Kong, Do Joong Park, Hyunsoo Chung, Soo-Jeong Cho, Seock-Ah Im, Yoonjin Kwak, Hye Seung Lee, Eui Kyu Chie, Jimmy Bok Yan So, Zekuan Xu, Narikazu Boku, Jiafu Ji, Yuko Kitagawa, Raul J Rosenthal, Takeshi Sano, Han-Kwang Yang

{"title":"Patients participation in multidisciplinary management in gastric cancer: regulation comparison and expert survey among major countries.","authors":"Kyoyoung Park, Hyuk-Joon Lee, Seong-Ho Kong, Do Joong Park, Hyunsoo Chung, Soo-Jeong Cho, Seock-Ah Im, Yoonjin Kwak, Hye Seung Lee, Eui Kyu Chie, Jimmy Bok Yan So, Zekuan Xu, Narikazu Boku, Jiafu Ji, Yuko Kitagawa, Raul J Rosenthal, Takeshi Sano, Han-Kwang Yang","doi":"10.14216/kjco.25365","DOIUrl":"10.14216/kjco.25365","url":null,"abstract":"Purpose: In Korea, the Health Insurance Review and Assessment Service (HIRA) mandates patient participation in outpatient multidisciplinary team (MDT) meetings as part of national cancer quality assessment. However, the necessity of involving patients and families in MDT discussions remains debatable. This study explored international expert perspectives on patient participation in gastric cancer MDTs.Methods: A cross-national expert survey was conducted in September 2021 among 15 gastric cancer specialists from Korea, China, Japan, Singapore, and the United States. The survey assessed the frequency of patient and family member attendance, perceived pros and cons, and preferences regarding mandatory versus selective involvement. Additionally, MDT structures and policies were reviewed by countries.Results: Most respondents reported that patients and families rarely or never attend MDT meetings: nine stated that patients are never included, three reported \"usually not,\" and three indicated \"sometimes.\" None consistently included patients. The most cited benefits were sharing opinions with patients and families simultaneously, followed by improved explanation of treatment and legal protection. Major concerns included hindered discussion, inefficiency, and logistical challenges. Only four respondents supported routine participation, while 11 favored case-dependent involvement.Conclusion: International experts do not widely support mandatory patient participation in MDT meetings. A flexible approach that allows MDTs to operate with or without patient involvement may better reflect actual clinical practice.","PeriodicalId":74045,"journal":{"name":"Korean journal of clinical oncology","volume":"21 3","pages":"143-149"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12784146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0