Journal of Yeungnam medical science最新文献

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Factors associated with musculoskeletal pain in professional dancers, including lapse period of group practice due to the COVID-19 outbreak: repeated-measures analysis. 职业舞蹈演员肌肉骨骼疼痛的相关因素,包括 COVID-19 爆发导致的集体练习中断期:重复测量分析。
IF 1
Journal of Yeungnam medical science Pub Date : 2024-07-01 Epub Date: 2024-05-17 DOI: 10.12701/jyms.2024.00171
Kiook Baek, Yu-Mi Choi, Joon Sakong
{"title":"Factors associated with musculoskeletal pain in professional dancers, including lapse period of group practice due to the COVID-19 outbreak: repeated-measures analysis.","authors":"Kiook Baek, Yu-Mi Choi, Joon Sakong","doi":"10.12701/jyms.2024.00171","DOIUrl":"10.12701/jyms.2024.00171","url":null,"abstract":"<p><strong>Background: </strong>This study investigated the prevalence and associated factors of musculoskeletal pain among professional dancers who experienced a lapse in group practice due to coronavirus disease 2019.</p><p><strong>Methods: </strong>General characteristics, practice time, region of musculoskeletal pain due to injury using the visual numeric scale (VNS), and causative motion were surveyed among professional dancers. Pain of VNS 0 to 3 was categorized as \"no or minor,\" 4 to 6 was categorized as \"moderate,\" and 7 to 10 was categorized as \"severe.\" The causal motions of musculoskeletal pain were analyzed according to body region. Factors other than motion associated with pain were also analyzed.</p><p><strong>Results: </strong>In total, 368 participants were included. In the univariate analysis, age and practice time were positively associated with \"moderate\" pain. Practice time, dance experience, and postural accuracy were positively associated with \"severe\" pain, as was performing Korean traditional dance. In the multivariable analysis, practice time, group practice, and age were positively associated with pain of VNS 4 to 10, and practice time, group practice, and Korean traditional dance were positively associated with pain of VNS 7 to 10.</p><p><strong>Conclusion: </strong>Among the factors related to dancer training, practice time, group practice, and dance type affect the occurrence of pain.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring comprehensive insights into pediatric obesity. 探索对小儿肥胖症的全面认识。
IF 1
Journal of Yeungnam medical science Pub Date : 2024-07-01 Epub Date: 2024-07-09 DOI: 10.12701/jyms.2024.00500
Yong Hee Hong
{"title":"Exploring comprehensive insights into pediatric obesity.","authors":"Yong Hee Hong","doi":"10.12701/jyms.2024.00500","DOIUrl":"10.12701/jyms.2024.00500","url":null,"abstract":"","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of pitavastatin on erythrocyte membrane fatty acid content in patients with chronic kidney disease: two-arm parallel randomized controlled trial. 匹伐他汀对慢性肾病患者红细胞膜脂肪酸含量的影响:双臂平行随机对照试验。
IF 1
Journal of Yeungnam medical science Pub Date : 2024-07-01 Epub Date: 2024-05-08 DOI: 10.12701/jyms.2024.00094
Minna Kim, Seong Eun Kim, Su Mi Lee, Won Suk An
{"title":"Effect of pitavastatin on erythrocyte membrane fatty acid content in patients with chronic kidney disease: two-arm parallel randomized controlled trial.","authors":"Minna Kim, Seong Eun Kim, Su Mi Lee, Won Suk An","doi":"10.12701/jyms.2024.00094","DOIUrl":"10.12701/jyms.2024.00094","url":null,"abstract":"<p><strong>Background: </strong>Statins reduce the risk of cardiovascular events in patients with chronic kidney disease (CKD). Although diabetes mellitus (DM) is a reported side effect of statin treatment, some studies have indicated that pitavastatin does not cause DM. The present study investigated the effect of pitavastatin on the fatty acid (FA) content of erythrocyte membranes, which affects the occurrence of DM and cardiovascular diseases. In addition, changes in adiponectin and glycated hemoglobin (HbA1c) levels were evaluated after pitavastatin treatment.</p><p><strong>Methods: </strong>A total of 45 patients were enrolled, 28 of whom completed the study. Over 24 weeks, 16 patients received 2 mg pitavastatin and 12 patients received 10 mg atorvastatin. Dosages were adjusted after 12 weeks if additional lipid control was required. There were 10 and nine patients with DM in the pitavastatin and atorvastatin groups, respectively. Erythrocyte membrane FAs and adiponectin levels were measured using gas chromatography and enzyme-linked immunosorbent assay, respectively.</p><p><strong>Results: </strong>In both groups, saturated FAs, palmitic acid, trans-oleic acid, total cholesterol, and low-density lipoprotein cholesterol levels were significantly lower than those at baseline. The arachidonic acid (AA) content in the erythrocyte membrane increased significantly in the pitavastatin group, but adiponectin levels were unaffected. HbA1c levels decreased in patients treated with pitavastatin. No adverse effects were associated with statin treatment.</p><p><strong>Conclusion: </strong>Pitavastatin treatment in patients with CKD may improve glucose metabolism by altering erythrocyte membrane AA levels. In addition, pitavastatin did not adversely affect glucose control in patients with CKD and DM.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140878111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound imaging and guidance in the management of myofascial pain syndrome: a narrative review. 肌筋膜疼痛综合征治疗中的超声成像和引导:综述。
IF 1
Journal of Yeungnam medical science Pub Date : 2024-07-01 Epub Date: 2024-06-17 DOI: 10.12701/jyms.2024.00416
Wei-Ting Wu, Ke-Vin Chang, Vincenzo Ricci, Levent Özçakar
{"title":"Ultrasound imaging and guidance in the management of myofascial pain syndrome: a narrative review.","authors":"Wei-Ting Wu, Ke-Vin Chang, Vincenzo Ricci, Levent Özçakar","doi":"10.12701/jyms.2024.00416","DOIUrl":"10.12701/jyms.2024.00416","url":null,"abstract":"<p><p>Myofascial pain syndrome (MPS) is a common musculoskeletal disorder characterized by muscle pain, tenderness, and trigger points. Ultrasonography has emerged as a key tool for diagnosing and treating MPS owing to its ability to provide precise, minimally invasive guidance. This review discusses the use of ultrasonography in various approaches to evaluate and manage MPS. Studies have shown that shear-wave sonoelastography can effectively assess muscle elasticity and offer insights into trapezius stiffness in patients with MPS. Ultrasound-guided interfascial hydrodissection, especially with visual feedback, has demonstrated effectiveness in treating trapezius MPS. Similarly, ultrasound-guided rhomboid interfascial plane blocks and perimysium dissection for posterior shoulder MPS have significantly reduced pain and improved quality of life. The combination of extracorporeal shockwave therapy with ultrasound-guided lidocaine injections has been particularly successful in reducing pain and stiffness in trapezius MPS. Research regarding various guided injections, including dry needling, interfascial plane blocks, and fascial hydrodissection, emphasizes the importance of ultrasonography for accuracy and safety. Additionally, ultrasound-guided delivery of local anesthetics and steroids to the quadratus lumborum muscle has shown lasting pain relief over a 6-month period. Overall, these findings highlight the pivotal role of ultrasonography in the assessment and treatment of MPS.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141461186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What is the disease burden from childhood and adolescent obesity?: a narrative review. 儿童和青少年肥胖症造成的疾病负担是什么?
IF 1
Journal of Yeungnam medical science Pub Date : 2024-07-01 Epub Date: 2024-06-27 DOI: 10.12701/jyms.2024.00360
Eun Byoul Lee
{"title":"What is the disease burden from childhood and adolescent obesity?: a narrative review.","authors":"Eun Byoul Lee","doi":"10.12701/jyms.2024.00360","DOIUrl":"10.12701/jyms.2024.00360","url":null,"abstract":"<p><p>The prevalence of childhood and adolescent obesity has increased and exacerbated during the coronavirus disease 2019 pandemic, both in Korea and globally. Childhood and adolescent obesity poses significant risks for premature morbidity and mortality. The development of serious comorbidities depends not only on the duration of obesity but also on the age of onset. Obesity in children and adolescents affects almost all organ systems, including the endocrine, cardiovascular, gastrointestinal, reproductive, nervous, and immune systems. Obesity in children and adolescents affects growth, cognitive function, and psychosocial interactions during development, in addition to aggravating known adult comorbidities such as type 2 diabetes mellitus, hypertension, dyslipidemia, nonalcoholic fatty liver disease, obstructive sleep apnea, and cancer. Childhood and adolescent obesity are highly associated with increased cardiometabolic risk factors and prevalence of metabolic syndrome. The risk of cardiovascular and metabolic diseases in later life can be considerably decreased by even a small weight loss before the onset of puberty. Childhood and adolescent obesity is a disease that requires treatment and is associated with many comorbidities and disease burdens. Therefore, early detection and therapeutic intervention are crucial.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141461187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How much does clinical prediagnosis correlate with electrophysiological findings?: a retrospective study. 临床诊断前与电生理学发现的相关性有多大?
IF 1
Journal of Yeungnam medical science Pub Date : 2024-07-01 Epub Date: 2024-07-05 DOI: 10.12701/jyms.2024.00381
Selda Çiftci İnceoğlu, Aylin Ayyıldız, Figen Yılmaz, Banu Kuran
{"title":"How much does clinical prediagnosis correlate with electrophysiological findings?: a retrospective study.","authors":"Selda Çiftci İnceoğlu, Aylin Ayyıldız, Figen Yılmaz, Banu Kuran","doi":"10.12701/jyms.2024.00381","DOIUrl":"10.12701/jyms.2024.00381","url":null,"abstract":"<p><strong>Background: </strong>Electrodiagnostic testing (EDX) is important in the diagnosis and follow-up of neuropathic and myopathic diseases. This study aimed to demonstrate the compatibility between clinical prediagnosis and electrophysiological findings.</p><p><strong>Methods: </strong>EDX results from 2004 to 2020 at the physical medicine and rehabilitation (PM&R) clinic were screened. Tests with missing data, reevaluation studies, and cases of peripheral facial paralysis were excluded. The clinical prediagnosis and EDX results were recorded, and their compatibility was evaluated.</p><p><strong>Results: </strong>A total of 2,153 tests were included in this study. The mean age was 49.0±13.9 years and 1,533 of them (71.2%) were female. The most frequently referred clinic was the PM&R clinic (90.0%). Numbness (73.6%) was the most common complaint, followed by pain (15.3%) and weakness (13.9%). The most common prediagnosis was entrapment neuropathy (55.3%), radiculopathy (16.1%), and polyneuropathy (15.7%). Carpal tunnel syndrome was the most frequently identified type of entrapment neuropathy (78.3%). Six hundred and seventy EDX results (31.1%) were within normal limits. While the EDX results were consistent with the prediagnosis in 1,328 patients (61.7%), a pathology different from the prediagnosis was detected in 155 patients (7.2%). In the discrepancy group, the most common pathologies were entrapment neuropathy (51.7%), polyneuropathy (17.3%), and radiculopathy (15.1%). The most common neuropathy type was carpal tunnel syndrome (79.3%).</p><p><strong>Conclusion: </strong>After adequate anamnesis and physical and neurological examinations, requesting further appropriate tests will increase the prediagnosis accuracy and prevent unnecessary expenditure of time and labor.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141536092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with musculoskeletal pain in professional dancers, including lapse period of group practice due to the COVID-19 outbreak: repeated-measures analysis. 职业舞蹈演员肌肉骨骼疼痛的相关因素,包括 COVID-19 爆发导致的集体练习中断期:重复测量分析。
Journal of Yeungnam medical science Pub Date : 2024-05-17 DOI: 10.12701/jyms.2024.00171
Kiook Baek, Yu-Mi Choi, Joon Sakong
{"title":"Factors associated with musculoskeletal pain in professional dancers, including lapse period of group practice due to the COVID-19 outbreak: repeated-measures analysis.","authors":"Kiook Baek, Yu-Mi Choi, Joon Sakong","doi":"10.12701/jyms.2024.00171","DOIUrl":"https://doi.org/10.12701/jyms.2024.00171","url":null,"abstract":"Background\u0000This study investigated the prevalence and associated factors of musculoskeletal pain among professional dancers who experienced a lapse in group practice due to coronavirus disease 2019.\u0000\u0000\u0000Methods\u0000General characteristics, practice time, region of musculoskeletal pain due to injury using the visual numeric scale (VNS), and causative motion were surveyed among professional dancers. Pain of VNS 0 to 3 was categorized as \"no or minor,\" 4 to 6 was categorized as \"moderate,\" and 7 to 10 was categorized as \"severe.\" The causal motions of musculoskeletal pain were analyzed according to body region. Factors other than motion associated with pain were also analyzed.\u0000\u0000\u0000Results\u0000In total, 368 participants were included. In the univariate analysis, age and practice time were positively associated with \"moderate\" pain. Practice time, dance experience, and postural accuracy were positively associated with \"severe\" pain, as was performing Korean traditional dance. In the multivariable analysis, practice time, group practice, and age were positively associated with pain of VNS 4 to 10, and practice time, group practice, and Korean traditional dance were positively associated with pain of VNS 7 to 10.\u0000\u0000\u0000Conclusion\u0000Among the factors related to dancer training, practice time, group practice, and dance type affect the occurrence of pain.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140965298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rehabilitative goals for patients undergoing lung retransplantation. 肺再移植患者的康复目标。
Journal of Yeungnam medical science Pub Date : 2024-04-05 DOI: 10.12701/jyms.2024.00241
M. Polastri, Robert M. Reed
{"title":"Rehabilitative goals for patients undergoing lung retransplantation.","authors":"M. Polastri, Robert M. Reed","doi":"10.12701/jyms.2024.00241","DOIUrl":"https://doi.org/10.12701/jyms.2024.00241","url":null,"abstract":"Lung retransplantation (LRT) involves a second or subsequent lung transplant (LT) in a patient whose first transplanted graft has failed. LRT is the only treatment option for irreversible lung allograft failure caused by acute graft failure, chronic lung allograft dysfunction, or postoperative complications of bronchial anastomosis. Prehabilitation (rehabilitation before LT), while patients are on the waiting list, is recognized as an essential component of the therapeutic regimen and should be offered throughout the waiting period from the moment of listing until transplantation. LRT is particularly fraught with challenges, and prehabilitation to reduce frailty is one of the few opportunities to address modifiable risk factors (such as functional and motor impairments) in a patient population in which there is clearly room to improve outcomes. Although rehabilitative outcomes and quality of life in patients receiving or awaiting LT have gained increased interest, there is a paucity of data on rehabilitation in patients undergoing LRT. Frailty is one of the few modifiable risk factors of retransplantation that is potentially preventable. As such, it is imperative that professionals involved in the field of retransplantation conduct research specifically exploring rehabilitative techniques and outcomes of value for patients receiving LRT, because this area remains unexplored.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140737930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimal examination for traumatic nerve/muscle injuries in earthquake survivors: a retrospective observational study. 地震幸存者创伤性神经/肌肉损伤的最佳检查:一项回顾性观察研究。
Journal of Yeungnam medical science Pub Date : 2024-04-05 DOI: 10.12701/jyms.2024.00087
Berkay Yalçınkaya, Büşranur Tüten Sağ, Mahmud Fazıl Aksakal, Pelin Analay, Hasan Ocak, M. Kara, B. Kaymak, Levent Özçakar
{"title":"Optimal examination for traumatic nerve/muscle injuries in earthquake survivors: a retrospective observational study.","authors":"Berkay Yalçınkaya, Büşranur Tüten Sağ, Mahmud Fazıl Aksakal, Pelin Analay, Hasan Ocak, M. Kara, B. Kaymak, Levent Özçakar","doi":"10.12701/jyms.2024.00087","DOIUrl":"https://doi.org/10.12701/jyms.2024.00087","url":null,"abstract":"Background\u0000Physiatrists are facing with survivors from disasters in both the acute and chronic phases of muscle and nerve injuries. Similar to many other clinical conditions, neuromusculoskeletal ultrasound can play a key role in the management of such cases (with various muscle/nerve injuries) as well. Accordingly, in this article, a recent single-center experience after the Turkey-Syria earthquake will be rendered.\u0000\u0000\u0000Methods\u0000Ultrasound examinations were performed for various nerve/muscle lesions in 52 earthquake victims referred from different cities. Demographic features, type of injuries, and applied treatment procedures as well as detailed ultrasonographic findings are illustrated.\u0000\u0000\u0000Results\u0000Of the 52 patients, 19 had incomplete peripheral nerve lesions of the brachial plexus (n=4), lumbosacral plexus (n=1), and upper and lower limbs (n=14).\u0000\u0000\u0000Conclusion\u0000The ultrasonographic approach during disaster relief is paramount as regards subacute and chronic phases of rehabilitation. Considering technological advances (e.g., portable machines), the use of on-site ultrasound examination in the (very) early phases of disaster response also needs to be on the agenda of medical personnel.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140739960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance of the BD MAX MDR-TB assay in a clinical setting and its impact on the clinical course of patients with pulmonary tuberculosis: a retrospective before-after study. BD MAX MDR-TB 检测法在临床环境中的性能及其对肺结核患者临床病程的影响:一项前后回顾性研究。
Journal of Yeungnam medical science Pub Date : 2024-04-05 DOI: 10.12701/jyms.2024.00024
Sung Jun Ko, Kui Hyun Yoon, Sang Hee Lee
{"title":"Performance of the BD MAX MDR-TB assay in a clinical setting and its impact on the clinical course of patients with pulmonary tuberculosis: a retrospective before-after study.","authors":"Sung Jun Ko, Kui Hyun Yoon, Sang Hee Lee","doi":"10.12701/jyms.2024.00024","DOIUrl":"https://doi.org/10.12701/jyms.2024.00024","url":null,"abstract":"Background\u0000Missing isoniazid (INH) resistance during tuberculosis (TB) diagnosis can worsen the outcomes of INH-resistant TB. The BD MAX MDR-TB assay (BD MAX) facilitates the rapid detection of TB and INH and rifampin (RIF) resistance; however, data related to its performance in clinical setting remain limited. Moreover, its effect on treatment outcomes has not yet been studied.\u0000\u0000\u0000Methods\u0000We compared the performance of BD MAX for the detection of INH/RIF resistances to that of the line probe assay (LPA) in patients with pulmonary TB (PTB), using the results of a phenotypic drug sensitivity test as a reference standard. The treatment outcomes of patients who used BD MAX were compared with those of patients who did not.\u0000\u0000\u0000Results\u0000Of the 83 patients included in the study, the BD MAX was used for an initial PTB diagnosis in 39 patients. The sensitivity of BD MAX for detecting PTB was 79.5%. The sensitivity and specificity of BD MAX for INH resistance were both 100%, whereas these were 50.0% and 95.8%, respectively, for RIF resistance. The sensitivity and specificity of BD MAX were comparable to those of LPA. The BD MAX group had a shorter time interval from specimen request to the initiation of anti-TB drugs (2.0 days vs. 5.5 days, p=0.001).\u0000\u0000\u0000Conclusion\u0000BD MAX showed comparable performance to conventional tests for detecting PTB and INH/RIF resistances. The implementation of BD MAX as a diagnostic tool for PTB resulted in a shorter turnaround time for the initiation of PTB treatment.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140735758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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