{"title":"Delayed traumatic pseudoaneurysm of a branch of the superior medial genicular artery treated with thrombin injection.","authors":"Young-Nam Roh, Choshin Kim","doi":"10.12701/jyms.2026.43.30","DOIUrl":"10.12701/jyms.2026.43.30","url":null,"abstract":"","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"30"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overview of the Journal of Yeungnam Medical Science in 2025: submission trends, journal metrics, and appreciation for peer reviewers.","authors":"Tae Gon Kim","doi":"10.12701/jyms.2026.43.16","DOIUrl":"10.12701/jyms.2026.43.16","url":null,"abstract":"","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"16"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12957858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146088093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Syuwari Azhar Azman, Sulhi Abidin, Galvin Sim Siang Lin, Mohd Haikal Muhamad Halil
{"title":"Qualitative exploration of manual dental records in the digital era using sociotechnical systems theory: insight from a teaching dental institution.","authors":"Syuwari Azhar Azman, Sulhi Abidin, Galvin Sim Siang Lin, Mohd Haikal Muhamad Halil","doi":"10.12701/jyms.2026.43.9","DOIUrl":"10.12701/jyms.2026.43.9","url":null,"abstract":"<p><strong>Background: </strong>Dental records are essential repositories of patient information that support diagnosis, treatment planning, continuity of care, and medicolegal accountability, making them a fundamental component of safe, effective, and transparent dental practices. This study aimed to explore the perceptions and experiences of academic and nonacademic clinical staff regarding a paper-based patient record system at a Malaysian public dental institute.</p><p><strong>Methods: </strong>A qualitative phenomenological design underpinned by the sociotechnical systems theory was employed. Purposive sampling recruited 20 full-time staff (10 academic, 10 nonacademic) with at least 1 year of experience using the manual record system and no prior training in electronic dental records. Semi-structured, one-on-one interviews were conducted between May 2025 and October 2025, audio-recorded, transcribed verbatim, and analyzed using Braun and Clarke's thematic analysis. Rigor was enhanced through independent coding, member checking, reflexive journaling, and adherence to the Consolidated Criteria for Reporting Qualitative Research checklist.</p><p><strong>Results: </strong>Four main themes were identified: (1) inefficiency and accessibility challenges; (2) accuracy, legibility, and record integrity; (3) continuity of care and patient safety risks; and (4) desire for digital transition and system improvements.</p><p><strong>Conclusion: </strong>Although manual paper-based dental records remain central to documentation in teaching dental institutions, they present growing inefficiencies and safety concerns, highlighting the need for sociotechnical-informed strategies that align human processes, technology, and institutional support to enhance recordkeeping and patient care.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"9"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12887119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145901910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of varicella vaccination on the epidemiology of herpes zoster and postherpetic neuralgia: a narrative review.","authors":"Hyeon-Soo Park, Gyeong-Jo Byeon","doi":"10.12701/jyms.2026.43.22","DOIUrl":"10.12701/jyms.2026.43.22","url":null,"abstract":"<p><p>Varicella-zoster virus (VZV) establishes lifelong latency following primary infection and can reactivate later in life to cause herpes zoster (HZ) and its debilitating complication postherpetic neuralgia (PHN). The implementation of varicella vaccinations has profoundly altered the epidemiological landscape of VZV. This narrative review examines the current literature to evaluate the impact of these vaccination programs on the incidence of HZ and PHN. Early mathematical models based on the \"exogenous boosting\" hypothesis predicted a substantial surge in adult HZ due to reduced exposure to circulating wild-type virus. However, long-term epidemiological data demonstrate that the incidence of adult HZ was already increasing prior to the introduction of vaccination programs and did not accelerate post-implementation, suggesting other primary drivers, such as an aging population. This review highlights the significant decline in HZ incidence among vaccinated pediatric populations, as the attenuated vOka vaccine strain is substantially less prone to reactivation than the wild-type virus. Furthermore, HZ that does occur in vaccinated individuals tends to be milder, resulting in a reduced risk of progression to PHN. To address the persistent risk in older adults, a recombinant zoster vaccine is recommended as a highly effective secondary prevention strategy. Despite challenges, such as breakthrough infections and the need for long-term monitoring of vaccine-induced immunity, varicella vaccination remains a cornerstone of public health, offering broad protection across different ages. Further research is needed to fully understand the long-term impact of varicella vaccinations on the incidence of HZ and PHN and to identify additional risk factors for these conditions.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"22"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13107090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147476473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Byungkwan Park, Ji Hwan Kim, Gyu-Sik Choi, Min Cheol Chang
{"title":"A 70-year-old man presenting with weakness in the left hand and tingling pain in the ulnar aspect of the left hand.","authors":"Byungkwan Park, Ji Hwan Kim, Gyu-Sik Choi, Min Cheol Chang","doi":"10.12701/jyms.2026.43.11","DOIUrl":"10.12701/jyms.2026.43.11","url":null,"abstract":"","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"11"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12957856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145954119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Min Cheol Chang, Juyeon Kim, Jun Sung Moon, Wooktae Park, Gun Woo Lee, Yoo Jin Choo
{"title":"Development of an RGB-depth camera-based gait analysis system: a single-case study of a patient with stroke.","authors":"Min Cheol Chang, Juyeon Kim, Jun Sung Moon, Wooktae Park, Gun Woo Lee, Yoo Jin Choo","doi":"10.12701/jyms.2026.43.15","DOIUrl":"10.12701/jyms.2026.43.15","url":null,"abstract":"<p><p>Alterations in gait patterns often indicate health status, and their analysis enables the diagnosis and assessment of various health conditions. This study aimed to develop a noncontact gait analysis system using red, green, and blue-depth (RGB-D) cameras and to evaluate its potential clinical applicability. A single case study was conducted to assess changes in the gait patterns of a patient with stroke before and after the application of an ankle-foot orthosis. Twenty walking trials were recorded to evaluate the key gait parameters. The custom RGB-D camera-based gait analysis system demonstrated the potential to rapidly quantify key gait parameters in the patient. Compared with normative data, it effectively identified characteristic stroke-related gait impairments such as shorter step lengths and slower gait speeds. However, the intraclass correlation coefficient analysis indicated low measurement reliability. Although the stance time and minimum knee angle on the left and right sides exceeded the standard error of measurement (SEM), no changes exceeded the minimal detectable change (MDC) criteria. Moreover, other gait parameters did not show significant changes beyond SEM or MDC, limiting the interpretability of the results. Therefore, further technological developments and data collection are required to improve test-retest reliability and sensitivity to change.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"15"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12957859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146055416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jihyun Na, Jun Young Kim, Seok-Jong Lee, In Hee Lee, Soo Jung Lee
{"title":"Extended therapeutic efficacy of dacarbazine following prior treatment with immune checkpoint inhibitors in metastatic melanoma: a single center retrospective study in Korea.","authors":"Jihyun Na, Jun Young Kim, Seok-Jong Lee, In Hee Lee, Soo Jung Lee","doi":"10.12701/jyms.2026.43.14","DOIUrl":"10.12701/jyms.2026.43.14","url":null,"abstract":"<p><strong>Background: </strong>Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of advanced malignant melanoma. This study examined the real-world efficacy of dacarbazine in patients who had previously received pembrolizumab, based on the hypothesis that prior ICI treatment enhances the therapeutic response to subsequent chemotherapy.</p><p><strong>Methods: </strong>This retrospective study included 71 patients with histologically confirmed malignant melanoma treated at Kyungpook National University Chilgok Hospital (Daegu, Korea) between 2011 and 2023. The patients received dacarbazine for unresectable stage IIIC, IIID, or IV melanoma (American Joint Committee on Cancer, 8th edition).</p><p><strong>Results: </strong>Among the 71 patients, the median patient age was 64 years (range, 25-89 years). When categorized by melanoma subtype, 18 patients (25.4%) had acral melanoma, 40 (56.3%) had cutaneous melanoma, and 13 (18.3%) had mucosal melanoma. Sixteen of the dacarbazine-treated patients had not received pembrolizumab previously (DTI-only group), while 55 had (pem-DTI group). The median progression-free survival was 2.3 months in the DTI-only group and 3.9 months in the pem-DTI group (hazard ratio [HR], 0.246; 95% confidence interval [CI], 0.106-0.576; p=0.001). The median overall survival was 6.8 months in the DTI-only group and 19.0 months in the pem-DTI group (HR, 0.198; 95% CI, 0.068-0.574; p=0.003). The duration of response (DoR) was 4.64 months in the DTI group and 8.11 months in the pem-DTI group.</p><p><strong>Conclusion: </strong>This study demonstrated that the DoR to dacarbazine was prolonged following ICI therapy (4.64 months vs. 8.11 months). This indicates that prior ICI treatment may enhance tumor sensitivity to chemotherapy, making dacarbazine a viable option for treating refractory, relapsed, or progressive melanoma.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"14"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12887124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunotherapy in triple-negative breast cancer: mechanisms of resistance and emerging approaches: a narrative review.","authors":"Sung Ae Koh","doi":"10.12701/jyms.2026.43.17","DOIUrl":"10.12701/jyms.2026.43.17","url":null,"abstract":"<p><p>Triple-negative breast cancer (TNBC) is characterized by less treatment responsiveness and poorer prognosis than other breast cancer subtypes. The introduction of anti-programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) immunotherapy has expanded the therapeutic options beyond conventional chemotherapy, leading to the adoption of pembrolizumab-based regimens in both adjuvant and first-line palliative settings. However, in contrast to other tumor types that respond robustly to immune checkpoint inhibitors, the efficacy of PD-1/PD-L1 blockade in TNBC remains modest. Multiple factors contribute to this limited response, including the heterogeneity of PD-L1 expression, presence of an immunosuppressive tumor microenvironment regulated by complex immunomodulatory pathways, differences in mutational burden and neoantigen presentation, quantity and functional exhaustion of tumor-infiltrating lymphocytes, and variable synergy with combination partners. Numerous combination strategies have been actively investigated to enhance immunotherapeutic efficacy. Among these, antibody drug conjugates (ADCs) have shown the most promising results. The phase III ASCENT-04/KEYNOTE-D19 trial demonstrated that the combination of sacituzumab govitecan and pembrolizumab significantly improved progression-free survival in patients with PD-L1-positive metastatic TNBC, establishing this regimen as a potential new first-line standard, pending guideline adoption. Although the overall survival data are still immature, the trend appears to be favorable. Other ADCs are being explored in early phase studies, and targeted therapies such as poly(ADP-ribose) polymerase and protein kinase B inhibitors have also shown preliminary activity in smaller trials. Further refinement of these strategies through biomarker-driven, large-scale studies is warranted to identify the most effective combinations and to improve outcomes in patients with TNBC.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"17"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146127604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bogyeong Kim, Minjin Jeon, Yuseop Lee, Hyunji Reem, Seung Min Chung
{"title":"Association between thyroid function and 10-year cardiovascular disease risk of patients with diabetes: a cross-sectional study using KNHANES 2013-2014.","authors":"Bogyeong Kim, Minjin Jeon, Yuseop Lee, Hyunji Reem, Seung Min Chung","doi":"10.12701/jyms.2026.43.28","DOIUrl":"10.12701/jyms.2026.43.28","url":null,"abstract":"<p><strong>Background: </strong>This study investigated the association between thyroid function and the 10-year cardiovascular disease (CVD) risk in patients with diabetes.</p><p><strong>Methods: </strong>This retrospective cross-sectional study analyzed 246 patients with diabetes aged 30 to 79 years (weighted n=1,611,708) from the 2013 to 2014 Korea National Health and Nutrition Examination Survey. Individuals with a history of CVD, thyroid disease, or pregnancy were excluded. Thyroid function was categorized as euthyroid, hypothyroid, or hyperthyroid, based on serum thyroid-stimulating hormone (TSH) levels (reference in Koreans, 0.62-6.86 mIU/L). The 10-year CVD risk was estimated using the Predicting Risk of CVD EVENTs calculator.</p><p><strong>Results: </strong>The mean participant age was 54.3±10.1 years, with a male-to-female ratio of 1.41:1. Although patients with hypothyroid (14.1%) and hyperthyroid (15.7%) statuses showed a higher CVD risk than those with euthyroid status (12.3%), the difference was not statistically significant (p=0.337). However, in the hypothyroid group (n=11), TSH levels showed a moderate correlation with 10-year CVD risk (r=0.603, p<0.05), although this finding should be interpreted with caution owing to the small sample size. After adjusting for diabetes- and thyroid-related variables, TSH level was independently associated with higher estimated 10-year CVD risk, particularly in patients with a glycated hemoglobin level of <7% (adjusted coefficient, 0.17; 95% confidence interval, 0.05-0.29; p<0.05).</p><p><strong>Conclusion: </strong>Monitoring TSH levels in patients with well-controlled diabetes may provide additional information regarding the risk of CVD; however, prospective studies are needed to confirm the long-term prognostic value.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"28"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147635303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ji Yong Yeom, Soomin Kim, Hyeon Seung Yi, Juhee Min, Eun Kyung Choi
{"title":"Effect of intraoperative music on quality of recovery after arthroscopic knee surgery: a prospective, double-blind, randomized controlled trial.","authors":"Ji Yong Yeom, Soomin Kim, Hyeon Seung Yi, Juhee Min, Eun Kyung Choi","doi":"10.12701/jyms.2026.43.29","DOIUrl":"10.12701/jyms.2026.43.29","url":null,"abstract":"<p><strong>Background: </strong>Various perioperative therapeutic strategies have been used to minimize postoperative complications and enhance recovery. Music intervention has attracted increasing attention as a safe, noninvasive, and cost-effective approach with potential benefits for patient-centered postoperative outcomes. Accordingly, this study investigated the effect of intraoperative music on postoperative recovery quality, as assessed using the Quality of Recovery-40 (QoR-40) questionnaire, as well as its potential analgesic and antiemetic effects in patients undergoing arthroscopic knee surgery.</p><p><strong>Methods: </strong>Eighty-two patients were enrolled and allocated to either the music or control group. In the music group, patient-selected tracks were delivered intraoperatively via headphones. Postoperative recovery quality was assessed using the QoR-40 at 24 hours. Pain was evaluated 30 minutes, 2 hours, and 24 hours after arrival in the post-anesthesia care unit. The incidence of postoperative nausea and vomiting (PONV) was recorded at all time points.</p><p><strong>Results: </strong>Although the total QoR-40 scores did not differ between the groups, the music group demonstrated significantly higher physical comfort scores (p=0.006). The incidence of PONV at 24 hours was lower in the music group (p=0.048), whereas the postoperative pain scores and rescue analgesic requirements showed no significant differences at any assessment point.</p><p><strong>Conclusion: </strong>In patients undergoing arthroscopic surgery, intraoperative music was associated with improvements in physical comfort and PONV, despite no significant difference in the total QoR-40 score.</p>","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":"43 ","pages":"29"},"PeriodicalIF":1.4,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147647817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}