Journal of Yeungnam medical science最新文献_第10页

Analysis of single nucleotide polymorphisms associated with the vitamin D pathway in the placentas of women with gestational diabetes mellitus: a laboratory study. 妊娠期糖尿病患者胎盘中与维生素D通路相关的单核苷酸多态性分析:一项实验室研究

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-05-08 DOI: 10.12701/jyms.2023.00150

Mi Ju Kim, Hyun Mi Kim, Hyun-Hwa Cha, Won Joon Seong

{"title":"Analysis of single nucleotide polymorphisms associated with the vitamin D pathway in the placentas of women with gestational diabetes mellitus: a laboratory study.","authors":"Mi Ju Kim, Hyun Mi Kim, Hyun-Hwa Cha, Won Joon Seong","doi":"10.12701/jyms.2023.00150","DOIUrl":"10.12701/jyms.2023.00150","url":null,"abstract":"Background: The aim of this study was to analyze the single nucleotide polymorphisms (SNPs) of genes known to be involved in vitamin D metabolism in the placenta using the placental tissue of mothers diagnosed with gestational diabetes mellitus (GDM) to determine whether the SNPs and occurrence of GDM are related.Methods: We enrolled 80 women of the same gestational age, 40 with and 40 without GDM. The placenta was obtained from each woman after delivery and SNP genotyping was performed on seven SNPs in the CYP27B1 (rs10877012), CYP24A1 (rs2248359, rs6013897, and rs2209314), and GC (rs2282679, rs16847024, and rs3733359) genes. Maternal serum 25-hydroxyvitamin D levels were measured during the first trimester of pregnancy and before delivery.Results: At the time of delivery, vitamin D levels were lower (21.05±12.05 mg/dL vs. 31.31±20.72 mg/dL, p=0.012) and the frequency of vitamin D deficiency was higher (60.7% vs. 32.5%, p=0.040) in the GDM group. In women with GDM, the G allele of rs10877012 was more common (86.3% vs. 65.0%, p=0.002). The rs10877012 GG genotype was more common in the GDM group (72.5% vs. 42.5%, p=0.007) and the rs10877012 TT genotype was more common in the control group (12.5% vs. 0%, p=0.007).Conclusion: Mothers with GDM have lower serum concentrations of vitamin D before delivery than healthy controls and vitamin D deficiency is common. A polymorphism in CYP27B1 (rs10877012), is considered to be a cause of GDM pathogenesis.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S9-S16"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9785727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic performance of F-18 FDG PET or PET/CT for detection of recurrent gastric cancer: a systematic review and meta-analysis. F-18 FDG PET或PET/CT对胃癌复发的诊断价值:一项系统综述和荟萃分析

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-08-17 DOI: 10.12701/jyms.2023.00220

Chang In Choi, Jae Kyun Park, Tae Yong Jeon, Dae-Hwan Kim

{"title":"Diagnostic performance of F-18 FDG PET or PET/CT for detection of recurrent gastric cancer: a systematic review and meta-analysis.","authors":"Chang In Choi, Jae Kyun Park, Tae Yong Jeon, Dae-Hwan Kim","doi":"10.12701/jyms.2023.00220","DOIUrl":"10.12701/jyms.2023.00220","url":null,"abstract":"Background: This systematic review and meta-analysis investigated the diagnostic performance of F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) or PET/computed tomography (PET/CT) for the detection of disease recurrence after curative resection of gastric cancer.Methods: The PubMed and Embase databases, from the earliest available date of indexing through November 30, 2019, were searched for studies evaluating the diagnostic performance of F-18 FDG PET or PET/CT to detect recurrent disease after gastric cancer surgery.Results: Across 17 studies (1,732 patients), the pooled sensitivity for F-18 FDG PET or PET/CT was 0.82 (95% confidence interval [CI], 0.74-0.88) with heterogeneity of I2=76.5 (p<0.001), and the specificity was 0.86 (95% CI, 0.78-0.91) with heterogeneity of I2=94.2 (p<0.001). Likelihood ratio (LR) tests gave an overall positive LR of 6.0 (95% CI, 3.6-9.7) and negative LR of 0.2 (95% CI, 0.14-0.31). The pooled diagnostic odds ratio was 29 (95% CI, 13-63). The summary receiver operating characteristic curve indicates that the area under the curve was 0.91 (95% CI, 0.88-0.93).Conclusion: The current meta-analysis showed good sensitivity and specificity of F-18 FDG PET or PET/CT for detecting recurrent disease after curative resection of gastric cancer despite heterogeneity in ethnicity, recurrence rate, histology, and interpretation method.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S37-S46"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10389348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytotoxicity of dental self-curing resin for a temporary crown: an in vitro study. 临时牙冠用自固化树脂细胞毒性的体外研究。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-04-26 DOI: 10.12701/jyms.2023.00080

Jae-Wan Ko, Joon Sakong, Sohee Kang

{"title":"Cytotoxicity of dental self-curing resin for a temporary crown: an in vitro study.","authors":"Jae-Wan Ko, Joon Sakong, Sohee Kang","doi":"10.12701/jyms.2023.00080","DOIUrl":"10.12701/jyms.2023.00080","url":null,"abstract":"Background: Residual monomer tests using high-performance liquid chromatography and cytotoxicity tests were performed to analyze the effect on the oral mucosa of a self-curing resin for provisional crown production.Methods: A cytotoxicity test was performed to confirm whether leaked residual monomers directly affected oral mucosal cells. The cytotoxicity of the liquid and solid resin polymers was measured using a water-soluble tetrazolium (WST) test and microplate reader.Results: In the WST assay using a microplate reader, 73.4% of the cells survived at a concentration of 0.2% liquid resin polymer. The cytotoxicity of the liquid resin polymer was low at ≤0.2%. For the solid resins, when 100% of the eluate was used from each specimen, the average cell viability was 91.3% for the solid resin polymer and 100% for the hand-mixed self-curing resin, which is higher than the cell viability standard of 70%. The cytotoxicity of the solid resin polymer was low.Conclusion: Because the polymerization process of the self-curing resin may have harmful effects on the oral mucosa during the second and third stages, the solid resin should be manufactured indirectly using a dental model.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S1-S8"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9703961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasound-guided diagnosis/intervention for ischiofemoral impingement syndrome. 坐骨股撞击综合征的超声引导诊断/干预。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-07-12 DOI: 10.12701/jyms.2023.00500

Wei-Ting Wu, Ke-Vin Chang, Levent Özçakar

引用次数: 0

Evaluation of periodontal status in women with polycystic ovary syndrome versus healthy women: a cross-sectional study. 评估多囊卵巢综合征妇女与健康妇女的牙周状况:一项横断面研究。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-05-08 DOI: 10.12701/jyms.2023.00143

Sandhya Pavankumar, Pavan Kumar Yellarthi, Sandeep Jn, Ramanarayana Boyapati, Trinath Kishore Damera, Naveen Vital Kumar G

{"title":"Evaluation of periodontal status in women with polycystic ovary syndrome versus healthy women: a cross-sectional study.","authors":"Sandhya Pavankumar, Pavan Kumar Yellarthi, Sandeep Jn, Ramanarayana Boyapati, Trinath Kishore Damera, Naveen Vital Kumar G","doi":"10.12701/jyms.2023.00143","DOIUrl":"10.12701/jyms.2023.00143","url":null,"abstract":"Background: Polycystic ovary syndrome (PCOS) affects approximately 4% to 12% of females of reproductive age. Previous studies have shown an association between systemic and periodontal diseases. This study aimed to compare the prevalence of periodontal disease in women with PCOS and healthy women.Methods: A total of 196 women aged 17 to 45 years were included in this study. Oral hygiene index-simplified (OHI-S), gingival index (GI), community periodontal index (CPI), and loss of attachment (LA) were assessed. Individuals who smoked, were pregnant, had any systemic disease (such as type 1 or type 2 diabetes mellitus, cardiovascular disease, malignancy, osteoporosis, and thyroid dysfunction), had a history of systemic antibiotic use in the past three months, or received any periodontal intervention in the past 6 months of screening were excluded. Student t-test was used to analyze the data. A p-value of <0.05 was considered statistically significant.Results: Despite similar OHI-S scores (p=0.972) in the two groups, women with PCOS had significantly higher GI, CPI, and LA scores than healthy women (p<0.001).Conclusion: Periodontal disease was more prevalent in women with PCOS than in healthy women. This finding may be due to the synergistic effects of PCOS and periodontitis on proinflammatory cytokines. PCOS may have an effect on periodontal disease, and vice versa. Hence, education on periodontal health and early detection and intervention for periodontal diseases is of paramount importance in patients with PCOS.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S17-S22"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9785723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between total body muscle percentage and prevalence of non-alcoholic fatty liver disease in Korean adults findings from an 18-year follow-up: a prospective cohort study. 来自18年随访的韩国成年人全身肌肉百分比与非酒精性脂肪肝患病率之间的关系:一项前瞻性队列研究

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-08-29 DOI: 10.12701/jyms.2023.00605

Byoung Chan Ahn, Chul Yong Park, Jung Hee Hong, Ki Ook Baek

{"title":"Association between total body muscle percentage and prevalence of non-alcoholic fatty liver disease in Korean adults findings from an 18-year follow-up: a prospective cohort study.","authors":"Byoung Chan Ahn, Chul Yong Park, Jung Hee Hong, Ki Ook Baek","doi":"10.12701/jyms.2023.00605","DOIUrl":"10.12701/jyms.2023.00605","url":null,"abstract":"Background: This study aimed to elucidate the association between total lean muscle mass and the incidence of non-alcoholic fatty liver disease (NAFLD) in the adult Korean population.Methods: Utilizing data derived from the 18-year prospective cohort of the Korean Genome and Epidemiology Study, NAFLD was diagnosed via the hepatic steatosis index with an established cutoff value of 36. Lean muscle mass was assessed via bioelectrical impedance analysis and subsequently divided into tertiles. A generalized mixed model with a logit link was employed for repeated measures data analysis, accounting for potential confounders.Results: Analysis encompassed 7,794 participants yielding 49,177 measurements. The findings revealed a markedly increased incidence of NAFLD in the lower tertiles of muscle mass, specifically, tertile 1 (odds ratio [OR], 20.65; 95% confidence interval [CI], 9.66-44.11) and tertile 2 (OR, 4.57; 95% CI, 2.11-9.91), in comparison to tertile 3. Age-dependent decreases in the OR were observed within the tertile 1 group, with ORs of 10.12 at age of 40 years and 4.96 at age of 80 years. Moreover, each 1%-point increment in total muscle mass corresponded with an estimated OR of 0.87 (95% CI, 0.82-0.93) for NAFLD resolution.Conclusions: The study demonstrates a significant association between total muscle mass and NAFLD prevalence among Korean adults. Given the potential endocrine role of muscle mass in NAFLD pathogenesis, interventions aimed at enhancing muscle mass might serve as an effective public health strategy for mitigating NAFLD prevalence.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S47-S55"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10112217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual presentation of asymptomatic subacute lead-related ventricular perforation beyond the pericardium without pericardial effusion: a case report. 无心包积液的无症状亚急性铅相关性室性穿孔1例报告。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-05-31 DOI: 10.12701/jyms.2023.00171

Jihee Son, Lae-Young Jung

{"title":"Unusual presentation of asymptomatic subacute lead-related ventricular perforation beyond the pericardium without pericardial effusion: a case report.","authors":"Jihee Son, Lae-Young Jung","doi":"10.12701/jyms.2023.00171","DOIUrl":"10.12701/jyms.2023.00171","url":null,"abstract":"The clinical manifestations of subacute pacemaker lead-related cardiac perforations are highly variable. Patients with subacute perforations can present with a variety of symptoms, whereas those with acute perforations usually present with cardiac tamponade that necessitates emergent pericardiocentesis. A 32-year-old woman underwent pacemaker implantation for sick sinus syndrome. An active-fixation atrial lead was fixed to the right atrial appendage, and a ventricular lead was fixed to the right ventricle (RV) apex, with acceptable parameters. Two weeks postoperative, the patient visited the clinic for routine examination of the pacemaker parameters. Chest X-ray showed migration of the RV lead beyond the cardiac silhouette. Echocardiography revealed no evidence of pericardial effusion or tamponade. Computed tomography revealed that the RV lead was positioned beyond the RV and pericardium and into the anterior chest wall. Procedural lead revision was performed with cardiothoracic surgery backup. The lead was retracted after loosening the active-fixation screw and inserting the stylet. The lead was placed in the RV septum with active fixation. The procedure was completed without complications, and the patient was discharged after 3 days. Subacute lead perforations can present with various symptoms, and some patients may be asymptomatic without pericardial effusion. Altered lead parameters frequently provide the first indication for the diagnosis of cardiac perforation. Transvenous lead revision with surgical backup is an alternative to surgical extraction.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S105-S108"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9547767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical results of only antegrade del Nido cardioplegia infusion in conventional coronary artery bypass grafting: a retrospective study. 传统冠状动脉旁路移植术中仅顺行del Nido停搏液输注的手术效果:回顾性研究。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-06-28 DOI: 10.12701/jyms.2023.00283

Sang-Uk Park, Yo Han Bae, Yun Seok Kim, Kyungsub Song, Woo Sung Jang

{"title":"Surgical results of only antegrade del Nido cardioplegia infusion in conventional coronary artery bypass grafting: a retrospective study.","authors":"Sang-Uk Park, Yo Han Bae, Yun Seok Kim, Kyungsub Song, Woo Sung Jang","doi":"10.12701/jyms.2023.00283","DOIUrl":"10.12701/jyms.2023.00283","url":null,"abstract":"Background: Additional retrograde cardioplegia infusion in conventional coronary artery bypass grafting (CABG) was introduced to address the concern of inappropriate cardioplegia delivery through the stenotic coronary artery. However, this method is complex and requires repeated infusions. Therefore, we investigated the surgical outcomes of only antegrade cardioplegia infusion in conventional CABG.Methods: We included 224 patients who underwent isolated CABG between 2017 and 2019. The patients were divided into two groups according to the cardioplegia infusion method: antegrade cardioplegia infusion with del Nido solution (n=111, group I) and antegrade+retrograde cardioplegia infusion with blood cardioplegia solution (n=113, group II).Results: The sinus recovery time after release of the aorta cross-clamp was shorter in group I (3.8±7.1 minutes, n=98) than in group II (5.8±4.1 minutes, n=73) (p=0.033). The total cardioplegia infusion volume was lower in group I (1,998.6±668.6 mL) than in group II (7,321.0±2,865.3 mL) (p<0.001). Creatine kinase-MB levels were significantly lower in group I than in group II (p=0.039). Newly developed regional wall motion abnormalities on follow-up echocardiography were detected in two patients (1.8%) in group I and five patients (4.4%) in group II (p=0.233). There was no significant difference in ejection fraction improvement between the two groups (3.3%±9.3% in group I and 3.3%±8.7% in group II, p=0.990).Conclusion: The only antegrade cardioplegia infusion strategy in conventional CABG is safe and has no harmful effects.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S23-S28"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9690734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Some suggestions for pain physicians working in real-world clinical settings. 对在现实世界临床环境中工作的疼痛医生的一些建议。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-05-23 DOI: 10.12701/jyms.2023.00255

Jung Hwan Lee, Min Cheol Chang

引用次数: 0

Primary diffuse large B-cell lymphoma of the vulva: a case report. 外阴原发性弥漫性大b细胞淋巴瘤1例。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-04-25 DOI: 10.12701/jyms.2023.00108

Sun Yeon Kim, Ju Hwan Koo, Juhun Lee, Yu Jin Koo, Mi Jin Gu, Dae Hyung Lee

{"title":"Primary diffuse large B-cell lymphoma of the vulva: a case report.","authors":"Sun Yeon Kim, Ju Hwan Koo, Juhun Lee, Yu Jin Koo, Mi Jin Gu, Dae Hyung Lee","doi":"10.12701/jyms.2023.00108","DOIUrl":"10.12701/jyms.2023.00108","url":null,"abstract":"Diffuse large B-cell lymphoma (DLBCL) is a subtype of non-Hodgkin lymphoma (NHL) and is estimated to account for approximately 30% of all NHL cases. NHL can also occur in the female genital tract and accounts for approximately 1.5% of all NHL cases. Many doctors have difficulty diagnosing or treating vulvar DLBCL because of its very low prevalence. A 55-year-old woman presented with a solid mass on the right side of the vulva. No significantly enlarged lymph nodes were observed in the inguinal region. She underwent excisional biopsy at our institution. DLBCL was diagnosed based on histological examination. According to the Hans algorithm, the lesion was diagnosed as a non-germinal center B-cell-like subtype. The patient was referred to a hematologic oncologist. The disease stage was classified as IE according to the Ann Arbor staging classification. The patient received four cycles of chemotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone and localized radiation therapy with 36 Gy in 20 fractions. She showed complete remission and maintained this status on the latest computed tomography scan. Gynecologists should rule out lymphoma in patients presenting with a vulvar mass.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S87-S92"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9395773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0