Journal of Yeungnam medical science最新文献_第9页

Comparison of serum anti-Müllerian hormone between unilateral and bilateral ovarian endometriomas during follicular, luteal, and random menstrual phases: a retrospective study. 卵泡期、黄体期和随机月经期单侧和双侧卵巢子宫内膜瘤血清抗米勒激素的比较：一项回顾性研究。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-09-22 DOI: 10.12701/jyms.2023.00661

Juhun Lee, Jong Mi Kim, Gun Oh Chong, Dae Gy Hong, Yoon Hee Lee

{"title":"Comparison of serum anti-Müllerian hormone between unilateral and bilateral ovarian endometriomas during follicular, luteal, and random menstrual phases: a retrospective study.","authors":"Juhun Lee, Jong Mi Kim, Gun Oh Chong, Dae Gy Hong, Yoon Hee Lee","doi":"10.12701/jyms.2023.00661","DOIUrl":"10.12701/jyms.2023.00661","url":null,"abstract":"Background: Over the last two decades, serum levels of anti-Müllerian hormone (AMH) have been shown to be reliable markers of ovarian reserve. This study aimed to compare baseline serum AMH levels and well-controlled clinical factors between patients with unilateral and bilateral ovarian endometriomas during the menstrual phase.Methods: We conducted a retrospective study. We enrolled 136 patients aged 18 to 36 years who were diagnosed with unilateral or bilateral ovarian endometriomas. Serum AMH levels of all patients and their latest two to three menstrual cycles were measured before surgery for ovarian endometriomas. The latest menstrual cycle length ranged from 26 to 30 days. Patients with irregular menstruation, a recent medication history of hormonal drugs other than oral contraceptive pills, a previous history of ovarian surgery, or any medical history influencing ovarian function were excluded.Results: Of the 136 patients, 76 (55.9%) had unilateral ovarian endometriomas and 60 (44.1%) had bilateral ovarian endometriomas. Serum AMH levels were not significantly different between the two groups in the follicular phase, luteal phase, or at any random time point.Conclusion: Serum AMH levels were not significantly different between unilateral and bilateral ovarian endometriomas in the follicular and luteal phases, or at any random time during the menstrual cycle when various confounding factors were excluded.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S65-S72"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41164390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Incidence and risk factors of deep vein thrombosis and pulmonary thromboembolism after spinal cord disease at a rehabilitation unit: a retrospective study. 康复中心脊髓疾病后深静脉血栓形成和肺血栓栓塞的发生率和危险因素：一项回顾性研究。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-09-20 DOI: 10.12701/jyms.2023.00689

Yoonhee Kim, Minjae Jeong, Myung Woo Park, Hyun Iee Shin, Byung Chan Lee, Du Hwan Kim

{"title":"Incidence and risk factors of deep vein thrombosis and pulmonary thromboembolism after spinal cord disease at a rehabilitation unit: a retrospective study.","authors":"Yoonhee Kim, Minjae Jeong, Myung Woo Park, Hyun Iee Shin, Byung Chan Lee, Du Hwan Kim","doi":"10.12701/jyms.2023.00689","DOIUrl":"10.12701/jyms.2023.00689","url":null,"abstract":"Background: Deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) are major complications of spinal cord disease. However, studies of their incidence in Korean patients are limited. Thus, this study investigated the incidence and risk factors of DVT and PTE in Korean patients with spinal cord disease.Methods: We retrospectively analyzed the medical records of 271 patients with spinal cord disease who were admitted to a rehabilitation unit within 3 months of disease onset at a tertiary hospital. The presence of DVT and PTE was mainly determined using Doppler ultrasonography and chest embolism computed tomography. Risk factor analysis included variables such as sex, age, obesity, completeness of motor paralysis, neurological level of injury, cause of injury, lower extremity fracture, active cancer, and functional ambulation category (FAC) score.Results: The incidences of DVT and PTE in the patients with spinal cord disease were both 6.3%. Risk factor analysis revealed that age of ≥65 years (p=0.031) and FAC score of ≤1 (p=0.023) were significantly associated with DVT development. Traumatic cause of injury (p=0.028) and DVT (p<0.001) were significant risk factors of PTE.Conclusion: Patients with spinal cord disease developed DVT and PTE within 3 months of disease onset with incidence rates of 6.3% and 6.3%, respectively. Age of ≥65 years and an FAC of score ≤1 were risk factors for DVT. Traumatic cause of injury and DVT were risk factors for PTE. However, given the inconsistent results of previous studies, the risk factors for DVT and PTE remain inconclusive. Therefore, early screening for DVT and PTE should be performed in patients with acute-to-subacute spinal cord disease regardless of the presence or absence of these risk factors.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S56-S64"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41167302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Classical Hodgkin lymphoma following follicular lymphoma: a case report. 滤泡性淋巴瘤继发经典霍奇金淋巴瘤1例。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-08-17 DOI: 10.12701/jyms.2023.00584

Bomi Kim

{"title":"Classical Hodgkin lymphoma following follicular lymphoma: a case report.","authors":"Bomi Kim","doi":"10.12701/jyms.2023.00584","DOIUrl":"10.12701/jyms.2023.00584","url":null,"abstract":"The simultaneous, composite, or sequential occurrence of follicular lymphoma (FL) and classical Hodgkin lymphoma (HL), both of which originate from germinal center B-cell, is rare. Questions have been raised with regard to the type of tests that pathologists should perform when observing the presence of a \"large-cell lymphoma\" following an FL and what are the most critical pathological points for diagnosis. Here, we present a case of a classical HL following an FL after administering rituximab-bendamustine (R-Benda) chemotherapy. Furthermore, we also summarized the literature and compared this case with other HLs that followed FLs. A 55-year-old woman was diagnosed with a grade 3A FL of the breast and axillary lymph node masses. She completed six R-Benda chemotherapy cycles for stage IV FL. Twenty-three months after the diagnosis, follow-up image studies showed an increase in the size and number of the lesions. Biopsies of the neck lymph node and liver were performed, and the diagnosis was classical HL. Sequential or composite FL and HL may sometimes develop from the same clone because they share the same genetic alterations, such as B-cell lymphoma (Bcl)-2 or Bcl-6 translocation. When a large-cell lymphoma is found after the treatment of FL, classical HL should be considered a pathological differential diagnosis, and histological, immunohistochemical, or molecular investigations must be considered during the diagnostic process.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S113-S122"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10389346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thyroid storm caused by metastatic papillary thyroid carcinoma tissue after total thyroidectomy: a case report. 甲状腺全切除术后转移性甲状腺乳头状癌组织所致甲状腺风暴1例。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-05-17 DOI: 10.12701/jyms.2023.00199

So Hee Kwon, Min-Ji Kim, Sin Yeong Jung, Jae-Han Jeon

{"title":"Thyroid storm caused by metastatic papillary thyroid carcinoma tissue after total thyroidectomy: a case report.","authors":"So Hee Kwon, Min-Ji Kim, Sin Yeong Jung, Jae-Han Jeon","doi":"10.12701/jyms.2023.00199","DOIUrl":"10.12701/jyms.2023.00199","url":null,"abstract":"Thyroid storm is a life-threatening form of thyrotoxicosis and an endocrinological emergency. We present a case of thyroid storm in a patient with metastatic papillary thyroid cancer. A 67-year-old woman with a history of total thyroidectomy 4 years prior to presentation was admitted with deteriorating mental status, fever, and tachycardia. Laboratory tests revealed severe thyrotoxicosis. Although the patient had no residual thyroid tissue after total thyroidectomy, she had a previously diagnosed metastatic thyroid cancer lesion in the pelvic bone. Despite initial treatment with a standard thyroid storm regimen, the patient died 6 days after hospitalization. The patient had no history of Graves disease; however, a thyroxine receptor antibody was detected postmortem. The patient had a history of exposure to an iodine contrast agent, which is a rare cause of thyrotoxicosis. Thyroxine production from a differentiated thyroid carcinoma is rare but can be a source of clinically significant thyrotoxicosis in patients post-thyroidectomy. Overlapping Graves disease is a common stimulus; however, other causes, such as exogenous iodine, cannot be excluded. This case demonstrates that in the setting of metastatic thyroid carcinoma, thyrotoxicosis cannot be completely ruled out as a cause of suspicious symptoms, even in patients with a history of total thyroidectomy.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S93-S97"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9469703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cephalosporin-induced encephalopathy in patients with hematologic malignancies: a significant concern. 血液学恶性肿瘤患者的头孢菌素诱导脑病:一个值得关注的问题。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-11-14 DOI: 10.12701/jyms.2023.00864

Young Seob Park, Min Kyoung Kim, Kyung Hee Lee, Sung Ae Koh, Ji Yoon Jung, Byeong Il Jang, Se-Jin Lee

引用次数: 0

Performance evaluation of Barozen Lipid Plus for point-of-care testing of lipid profiles: a method comparison study. Barozen Lipid Plus用于脂质状况护理点测试的性能评估：一项方法比较研究。

IF 1

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-10-20 DOI: 10.12701/jyms.2023.00528

Soojoung Yu, Hwa Yeon Sun, Byungwook Yoo

{"title":"Performance evaluation of Barozen Lipid Plus for point-of-care testing of lipid profiles: a method comparison study.","authors":"Soojoung Yu, Hwa Yeon Sun, Byungwook Yoo","doi":"10.12701/jyms.2023.00528","DOIUrl":"10.12701/jyms.2023.00528","url":null,"abstract":"Background: The quick and easy nature of point-of-care (POC) testing devices allows regular monitoring of serum lipid levels to increase efficiency. The purpose of this study was to assess a POC lipid analyzer, Barozen Lipid Plus (MICO Biomed Co., Ltd.), which uses capillary blood to measure total cholesterol (TC), triglycerides (TGs), and high-density lipoprotein cholesterol (HDL-C).Methods: Capillary and venous blood samples were collected from 110 participants at a single center in Korea between June 10 and June 26, 2021. TC, TG, and HDL-C measurements using Barozen Lipid Plus were compared with measurements using our reference device, the Roche-Hitachi Cobas 8000 c702 (Hitachi High-Technologies Corporation). This study followed the guidelines of the Clinical and Laboratory Standards Institute and the Clinical Laboratory Improvement Amendments. We surveyed participants regarding the convenience of the POC device using a questionnaire following the completion of blood collection.Results: When compared to the reference equipment, the measurements obtained using Barozen Lipid Plus were more than 95% satisfactory within TC±10%, TG±25%, and HDL-C±30%. The coefficient of variation in the repeatability testing was within 5% for TC, 5% for TGs, and 7% for HDL-C. The survey results indicated high levels of satisfaction. No adverse events were reported.Conclusion: These findings suggest that Barozen Lipid Plus is reliable for measuring lipid profiles and can therefore be used to monitor lipid levels at the time and place of patient care.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S73-S80"},"PeriodicalIF":1.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49685871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare pathogenic variant identified in a heart transplant recipient with hereditary transthyretin amyloidosis: a case report. 在遗传性甲状腺转蛋白淀粉样变的心脏移植受者中发现一种罕见的致病变异:一例报告。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-05-30 DOI: 10.12701/jyms.2023.00241

Myeong Seop Kim, Soo Youn Lee, Kyung-Hee Kim

{"title":"A rare pathogenic variant identified in a heart transplant recipient with hereditary transthyretin amyloidosis: a case report.","authors":"Myeong Seop Kim, Soo Youn Lee, Kyung-Hee Kim","doi":"10.12701/jyms.2023.00241","DOIUrl":"10.12701/jyms.2023.00241","url":null,"abstract":"Hereditary transthyretin (ATTRv) amyloidosis is a rare and complex genetic disorder that can lead to life-threatening cardiac amyloidosis and rapid disease progression. Early diagnosis and treatment with disease-modifying drugs can improve patient outcomes; however, heart transplantation may be necessary in some patients. We present the unique case of a 65-year-old Korean woman diagnosed with ATTRv amyloidosis after experiencing progressive neurological symptoms, followed by heart failure. Despite the absence of significant symptoms of heart failure, subsequent screening revealed cardiac amyloid infiltration, which caused left ventricular hypertrophy and rapid disease progression. The patient underwent successful heart transplantation, and subsequent genetic testing revealed a pathogenic variant, NM_000371.3:c.425T>C (p.Val142Ala), which affects both the nerves and heart and has not been previously reported in Korea. Our report underscores the potential benefits of heart transplantation in managing advanced ATTRv amyloidosis and emphasizes the need for continued research on the genetic heterogeneity of the disease. Clinicians should consider ATTRv amyloidosis in the differential diagnosis of patients presenting with neurological symptoms and heart failure, particularly in those with a family history of the disease.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S98-S104"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9544863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Algorithm for multimodal medication therapy in patients with complex regional pain syndrome. 复杂局部疼痛综合征患者的多模式药物治疗算法。

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-07-12 DOI: 10.12701/jyms.2023.00360

Min Cheol Chang, Donghwi Park

{"title":"Algorithm for multimodal medication therapy in patients with complex regional pain syndrome.","authors":"Min Cheol Chang, Donghwi Park","doi":"10.12701/jyms.2023.00360","DOIUrl":"10.12701/jyms.2023.00360","url":null,"abstract":"Complex regional pain syndrome (CRPS), previously known as reflex sympathetic dystrophy and causalgia, is a clinical entity characterized by classic neuropathic pain, autonomic involvement, motor symptoms, and trophic changes in the skin, nails, and hair. Although various therapeutic modalities are used to control CRPS-related pain, severe pain due to CRPS often persists and progresses to the chronic phase. In this study, we constructed an algorithm for multimodal medication therapy for CRPS based on the established pathology of CRPS. Oral steroid pulse therapy is recommended for initial pain management in patients with CRPS. Oral steroid therapy can reduce peripheral and central neuroinflammation, contributing to the development of neuropathic pain during the acute and chronic phases. If steroid pulse therapy offers poor relief or is ineffective, treatment to control central sensitization in the chronic phase should be initiated. If pain persists despite all drug adjustments, ketamine with midazolam 2 mg before and after ketamine injection can be administered intravenously to inhibit the N-methyl D-aspartate receptor. If this treatment fails to achieve sufficient efficacy, intravenous lidocaine can be administered for 2 weeks. We hope that our proposed drug treatment algorithm to control CRPS pain will help clinicians appropriately treat patients with CRPS. Further clinical studies assessing patients with CRPS are warranted to establish this treatment algorithm in clinical practice.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S125-S128"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9773154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Analysis of single nucleotide polymorphisms associated with the vitamin D pathway in the placentas of women with gestational diabetes mellitus: a laboratory study. 妊娠期糖尿病患者胎盘中与维生素D通路相关的单核苷酸多态性分析:一项实验室研究

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-05-08 DOI: 10.12701/jyms.2023.00150

Mi Ju Kim, Hyun Mi Kim, Hyun-Hwa Cha, Won Joon Seong

{"title":"Analysis of single nucleotide polymorphisms associated with the vitamin D pathway in the placentas of women with gestational diabetes mellitus: a laboratory study.","authors":"Mi Ju Kim, Hyun Mi Kim, Hyun-Hwa Cha, Won Joon Seong","doi":"10.12701/jyms.2023.00150","DOIUrl":"10.12701/jyms.2023.00150","url":null,"abstract":"Background: The aim of this study was to analyze the single nucleotide polymorphisms (SNPs) of genes known to be involved in vitamin D metabolism in the placenta using the placental tissue of mothers diagnosed with gestational diabetes mellitus (GDM) to determine whether the SNPs and occurrence of GDM are related.Methods: We enrolled 80 women of the same gestational age, 40 with and 40 without GDM. The placenta was obtained from each woman after delivery and SNP genotyping was performed on seven SNPs in the CYP27B1 (rs10877012), CYP24A1 (rs2248359, rs6013897, and rs2209314), and GC (rs2282679, rs16847024, and rs3733359) genes. Maternal serum 25-hydroxyvitamin D levels were measured during the first trimester of pregnancy and before delivery.Results: At the time of delivery, vitamin D levels were lower (21.05±12.05 mg/dL vs. 31.31±20.72 mg/dL, p=0.012) and the frequency of vitamin D deficiency was higher (60.7% vs. 32.5%, p=0.040) in the GDM group. In women with GDM, the G allele of rs10877012 was more common (86.3% vs. 65.0%, p=0.002). The rs10877012 GG genotype was more common in the GDM group (72.5% vs. 42.5%, p=0.007) and the rs10877012 TT genotype was more common in the control group (12.5% vs. 0%, p=0.007).Conclusion: Mothers with GDM have lower serum concentrations of vitamin D before delivery than healthy controls and vitamin D deficiency is common. A polymorphism in CYP27B1 (rs10877012), is considered to be a cause of GDM pathogenesis.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S9-S16"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9785727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic performance of F-18 FDG PET or PET/CT for detection of recurrent gastric cancer: a systematic review and meta-analysis. F-18 FDG PET或PET/CT对胃癌复发的诊断价值:一项系统综述和荟萃分析

Journal of Yeungnam medical science Pub Date : 2023-11-01 Epub Date: 2023-08-17 DOI: 10.12701/jyms.2023.00220

Chang In Choi, Jae Kyun Park, Tae Yong Jeon, Dae-Hwan Kim

{"title":"Diagnostic performance of F-18 FDG PET or PET/CT for detection of recurrent gastric cancer: a systematic review and meta-analysis.","authors":"Chang In Choi, Jae Kyun Park, Tae Yong Jeon, Dae-Hwan Kim","doi":"10.12701/jyms.2023.00220","DOIUrl":"10.12701/jyms.2023.00220","url":null,"abstract":"Background: This systematic review and meta-analysis investigated the diagnostic performance of F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) or PET/computed tomography (PET/CT) for the detection of disease recurrence after curative resection of gastric cancer.Methods: The PubMed and Embase databases, from the earliest available date of indexing through November 30, 2019, were searched for studies evaluating the diagnostic performance of F-18 FDG PET or PET/CT to detect recurrent disease after gastric cancer surgery.Results: Across 17 studies (1,732 patients), the pooled sensitivity for F-18 FDG PET or PET/CT was 0.82 (95% confidence interval [CI], 0.74-0.88) with heterogeneity of I2=76.5 (p<0.001), and the specificity was 0.86 (95% CI, 0.78-0.91) with heterogeneity of I2=94.2 (p<0.001). Likelihood ratio (LR) tests gave an overall positive LR of 6.0 (95% CI, 3.6-9.7) and negative LR of 0.2 (95% CI, 0.14-0.31). The pooled diagnostic odds ratio was 29 (95% CI, 13-63). The summary receiver operating characteristic curve indicates that the area under the curve was 0.91 (95% CI, 0.88-0.93).Conclusion: The current meta-analysis showed good sensitivity and specificity of F-18 FDG PET or PET/CT for detecting recurrent disease after curative resection of gastric cancer despite heterogeneity in ethnicity, recurrence rate, histology, and interpretation method.","PeriodicalId":74020,"journal":{"name":"Journal of Yeungnam medical science","volume":" ","pages":"S37-S46"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10718600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10389348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0