癌痛患者的突破性疼痛和快速发作阿片类药物：叙述性综述。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-01-01 Epub Date: 2023-06-30 DOI:10.12701/jyms.2023.00367

Jinseok Yeo

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引用次数: 0

摘要

突破性疼痛是在使用阿片类药物控制背景疼痛的情况下出现的短暂性疼痛。40% 至 80% 的癌痛患者会出现突破性疼痛。尽管镇痛治疗有效，但患者及其护理人员经常感到疼痛未得到充分控制。因此，提高对突破性疼痛及其治疗的认识对所有治疗癌症患者的医生来说都至关重要。本文回顾了癌症患者突破性疼痛的定义、临床表现、准确诊断策略和最佳治疗方案。本综述的重点是速效阿片类药物的疗效和安全性，这些药物是治疗突破性疼痛的主要抢救药物。

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Breakthrough pain and rapid-onset opioids in patients with cancer pain: a narrative review.

Breakthrough pain is transitory pain that occurs despite the use of opioids for background pain control. Breakthrough pain occurs in 40% to 80% of patients with cancer pain. Despite effective analgesic therapy, patients and their caregivers often feel that their pain is not sufficiently controlled. Therefore, an improved understanding of breakthrough pain and its management is essential for all physicians caring for patients with cancer. This article reviews the definition, clinical manifestations, accurate diagnostic strategies, and optimal treatment options for breakthrough pain in patients with cancer. This review focuses on the efficacy and safety of rapid-onset opioids, which are the primary rescue drugs for breakthrough pain.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.