Journal of trace elements and minerals最新文献

{"title":"Understanding trace elements dynamics and environmental health: insights from Fish Mortality in Rajshahi, Bangladesh","authors":"A․H․M․Selim Reza ,&nbsp;Md․Shazzadur Rahman ,&nbsp;Fazal Md․Mohi Shine ,&nbsp;Md․Abu Bakar Siddique ,&nbsp;Md․Abdur Rahman ,&nbsp;Sudip Saha ,&nbsp;Abu Bakar Siddique ,&nbsp;Fawzia Adib Flowra","doi":"10.1016/j.jtemin.2025.100264","DOIUrl":"10.1016/j.jtemin.2025.100264","url":null,"abstract":"<div><h3>Introduction</h3><div>This study investigates the combined impact of trace metal contamination and environmental factors on fish mortality in aquaculture ponds in the Rajshahi region of Bangladesh. The primary objective is to assess how physicochemical parameters and trace metal concentrations interact with climatic conditions to influence fish health and survival.</div></div><div><h3>Materials and Methods</h3><div>Water, sediment, and fish tissue samples were collected and analyzed for arsenic (As), mercury (Hg), chromium (Cr), cadmium (Cd), and lead (Pb) using Atomic Absorption Spectrometry (AAS-240FS). Key physicochemical parameters such as pH, electrical conductivity (EC), total dissolved solids (TDS), and dissolved oxygen (DO) were measured. Climatic variables, including relative humidity and temperature, were recorded to evaluate their relationship with DO levels and fish mortality events.</div></div><div><h3>Results and Discussion</h3><div>Mean values of pH, EC, and TDS were 6.77, 433.4 µS cm⁻¹, and 209 mg <em>L</em>⁻¹, respectively. Trace metal concentrations in water followed the order Pb &gt; As &gt; Cr &gt; Hg &gt; Cd; in sediment, Cr &gt; Pb &gt; As &gt; Hg &gt; Cd; and in fish tissue, Cr &gt; Pb &gt; As &gt; Hg &gt; Cd. A significant inverse correlation was found between high relative humidity (90–95 %) and DO levels, which decreased from 4.00 mg <em>L</em>⁻¹ to 1.08 mg <em>L</em>⁻¹ well below the critical threshold of 5–6 mg <em>L</em>⁻¹ required for fish survival. Additionally, TDS exhibited a negative correlation with DO and a positive correlation with sedimentary arsenic, indicating that siltation from heavy rainfall contributes to oxygen depletion. The highest fish mortality, recorded on September 1, 2020, coincided with overcast conditions, elevated temperatures, and reduced photosynthetic activity, all of which exacerbated hypoxic stress.</div></div><div><h3>Conclusion</h3><div>The findings highlight the complex interplay between environmental stressors and trace metal pollution in aquaculture ponds. Regular water quality monitoring, pollution control, and adaptive management strategies are essential to reduce fish mortality risks and ensure the long-term sustainability of aquaculture in the region.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"14 ","pages":"Article 100264"},"PeriodicalIF":0.0,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elemental bioaccumulation as trophic discriminator in Southeast Alaska gray wolves: Marine-terrestrial diet shifts","authors":"Miranda Brohman ,&nbsp;Gretchen H. Roffler ,&nbsp;Dimitrios G. Giarikos ,&nbsp;David W. Kerstetter ,&nbsp;Amy C. Hirons","doi":"10.1016/j.jtemin.2025.100263","DOIUrl":"10.1016/j.jtemin.2025.100263","url":null,"abstract":"<div><div>Gray wolves (<em>Canis lupus</em>) in Southeast Alaska exhibit diverse foraging strategies shaped by regional ecological factors. Stable isotope (δ¹³C and δ¹⁵N) and trace element (TE) analyses were used to evaluate dietary patterns and contaminant exposure in four wolf populations from northern Lynn Canal (Douglas Island, Juneau, Gustavus, and Pleasant Island) from wolf hair samples collected from 2013–2021, along with sea otter (<em>Enhydra lutris</em>) hair in wolf scat collected in 2018–2019. Stable isotope ratios revealed that Juneau wolves predominantly consume terrestrial prey such as Sitka black-tailed deer (<em>Odocoileus hemionus sitkensis</em>) and mountain goats (<em>Oreamnos americanus</em>), and wolves on Douglas Island mainly consume Sitka black-tailed deer. In contrast, wolves from Gustavus and Pleasant Island exhibited enriched isotopic signatures, indicating a significant incorporation of marine-derived prey, particularly sea otters. Analysis of TEs revealed higher concentrations in wolves consuming marine-based diets, highlighting potential bioaccumulation risks compared to terrestrial-based diets. Gustavus wolves had the highest geometric mean concentrations for Cr (1.63 µg/g), Hg (4.24 µg/g), and Mo (0.180 µg/g) while Pleasant Island wolves had the highest for Al (153 µg/g), Cd (0.160 µg/g), Co (0.208 µg/g), Fe (343 µg/g), Mn (52.1 µg/g), and V (0.592 µg/g). The Se:Hg ratio also indicated a higher likelihood of mercury toxicity in all wolf populations, underscoring environmental health concerns. Assessing the dietary preferences and prey availability of apex predators, alongside the potential risks posed by elevated TE concentrations, is essential for informing targeted conservation strategies aimed at safeguarding these species across both coastal and inland Southeast Alaska.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"14 ","pages":"Article 100263"},"PeriodicalIF":0.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145266274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of peeled and unpeeled white and red cocoa yam varieties by mineral and vitamin profiles","authors":"Elijah O. Odesanmi ,&nbsp;Deborah O. Jesusanmi ,&nbsp;Olorunfemi R. Molehin ,&nbsp;Modupe A Ogundare ,&nbsp;Omotade I. Oloyede ,&nbsp;Yemisi Alli Smith ,&nbsp;Bukola T. Aluko ,&nbsp;Olajumoke O. Ojo ,&nbsp;Olorunfemi Ojo ,&nbsp;Seun Akomolafe","doi":"10.1016/j.jtemin.2025.100262","DOIUrl":"10.1016/j.jtemin.2025.100262","url":null,"abstract":"<div><h3>Background</h3><div>Cocoa yam (<em>Xanthosoma sagittifolium</em>) is a starchy root vegetable that is widely consumed in tropical regions. As an underutilized crop, its potential as a functional food remains largely unexplored.</div></div><div><h3>Objectives</h3><div>The aim of this current study was to compare peeled and unpeeled white and red cocoa yam varieties, specifically by their emergent mineral and vitamin profiles</div></div><div><h3>Methods</h3><div>The research employed an Atomic Absorption Spectrophotometer (AAS) to detect minerals like iron (Fe), magnesium (Mg), lead (Pb), manganese (Mn), sodium (Na), and potassium (K), likewise HPLC-UV to detect vitamins like vitamin E,C,A and vitamin K present in peeled and unpeeled white and red cocoa yam.</div></div><div><h3>Results</h3><div>The mineral analysis revealed that the unpeeled red cocoa yam (URCY) and unpeeled white cocoa yam (UWCY) consistently displayed significantly higher levels of macrominerals, such as calcium (123.238±0.02 mg 100 g in UWCY and 115.793±0.56 mg 100 g in URCY), magnesium, sodium, and potassium, compared to the peeled counterparts (PWCY and PRCY). The unpeeled varieties also exhibited greater concentrations of trace minerals, including iron (17.987±0.02 mg 100<em>g</em>⁻¹ in URCY and 63.320±0.03 mg 100 g in UWCY), copper, zinc, and manganese. Interestingly, all varieties had negligible levels of lead, indicating minimal contamination. The vitamin composition analysis further highlighted the importance of the peel. The unpeeled URCY variety demonstrated the highest levels of fat-soluble vitamins, such as vitamin A (3.947±0.04 μg 100<em>g</em>⁻¹ URCY and 4.315±0.01 μg 100 g in UWCY), vitamin E, and vitamin K. For water-soluble vitamins, URCY also had the greatest amounts of vitamin C (8.652±0.02 mg 100<em>g</em>⁻¹) and vitamin B6.</div></div><div><h3>Conclusion</h3><div>These findings suggest that the peel of the cocoa yam is a rich source of various essential minerals and vitamins, which are known to confer numerous health benefits. Consuming cocoa yam with the peel intact can provide greater nutritional and functional food benefits to consumers compared to peeled varieties.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"14 ","pages":"Article 100262"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145106152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health risks from the harmful mineral elements’ extractability in the Lubumbashi’s three most used medicinal plants root barks","authors":"Cedrick S. Mutombo ,&nbsp;Cynthia M. Kibwe ,&nbsp;Gael N. Mavungu ,&nbsp;Henry M. Manya ,&nbsp;Arsene T. Kabamba ,&nbsp;Vianney N. Ntabaza ,&nbsp;Salvius A. Bakari ,&nbsp;Joh B. Kahumba","doi":"10.1016/j.jtemin.2025.100261","DOIUrl":"10.1016/j.jtemin.2025.100261","url":null,"abstract":"<div><h3>Background</h3><div>To date, no studies have been reported on the mineral element’s extractability in medicinal plants from Lubumbashi, despite the harmful mineral element’s accumulation in medicinal plant species from this region. This study evaluates (<em>i</em>) the extractability of mineral elements in aqueous extracts of root barks from 3 of Lubumbashi’s most used medicinal plants and (<em>ii</em>) the health risk from the harmful mineral elements bioaccessibility.</div></div><div><h3>Methods</h3><div>Root bark powders of <em>Oldfieldia dactyllophylla</em> (Welw.exOliv.) J. Léonard, <em>Phyllanthus muellerianus</em> (Kuntze) Exell, and <em>Securidaca longepedunculata</em> Fresen, collected from 3 sites in the Lubumbashi region, were macerated (2 h, 6 h, 12 h, and 24 h), infused and decocted in distilled water. These extracts, corresponding crude samples (powders), and used solvent were subjected to inductively coupled plasma atomic emission spectroscopy.</div></div><div><h3>Results</h3><div>4 macroelements (Ca, K, Na, Mg), 6 trace elements (Co, Cu, Fe, Mn, Zn, Se), and 5 non-essential elements (Ag, Al, Cd, Pb, Ni), were detected and quantified in the crude sample of each species. Cd, Co, Fe, and Na were most extracted (82.5, 64.3, 89.8, and 55.6 % respectively) by infusion in <em>P. muellerianus</em>; Mg by infusion (41.3 %), and Cd by decoction (37.1 %) in <em>O. dactylophylla</em>; as well as Se and Co by infusion (74.6 and 55.4 % respectively) in <em>S. longepedunculata</em>. Mineral elements daily intake trough the studied extracts decreased in order <em>P. muellerianus</em> &gt; <em>S. longepedunculata</em> &gt; <em>O. dactyllophylla</em>, reflecting the mineral content of their crude drugs, and showing the dangerousness of <em>P. muellerianus</em>, known to bioaccumulate harmful minerals including Cd and Pb. Target hazard quotients (HTQ) were &gt; 1 for Al, Cd and Pb, multiplying the non-carcinogenic toxic hazard index (HI) by 40, 22, and 32 respectively for infused, decocted and 24 h macerated <em>P. muellerianus</em>. However, the carcinogenic risk was significantly negligible (CR &lt; 0.0001) for extracts of all the analyzed species.</div></div><div><h3>Conclusion</h3><div>Ingestion of 367 mL of <em>O. dactyllophylla</em> root bark aqueous extracts would be harmless, whereas extraction on the same samples of <em>S. longepedunculata</em> and <em>P. muellerianus</em> should preferably be 2 to 12 h maceration.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"14 ","pages":"Article 100261"},"PeriodicalIF":0.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-anemic potential of cerium oxide nanoparticles in diet-induced obese rats: Role of hepcidin, oxidative stress, and inflammation","authors":"Samir A.E. Bashandy ,&nbsp;Marawan A. Elbaset ,&nbsp;Fatma A.A. Ibrahim ,&nbsp;Sherif A. Abdelmottaleb Moussa ,&nbsp;Noha A. Abd El-Latif ,&nbsp;Sherif M. Afifi ,&nbsp;Tuba Esatbeyoglu ,&nbsp;Ahmed M.A. El-Seidy","doi":"10.1016/j.jtemin.2025.100260","DOIUrl":"10.1016/j.jtemin.2025.100260","url":null,"abstract":"<div><h3>Background</h3><div>Obesity and overweight result in low-grade systemic inflammation associated with an increase of oxidative stress and hepcidin discharging and lowering iron absorption giving rise to anemia. This study is aimed to investigate the anti-anemic effect of cerium oxide nanoparticles (CeO₂NPs) in obese rats via investigation of hepcidin expression, ferritin, inflammatory markers, and oxidative stress parameters</div></div><div><h3>Methods</h3><div>CeO₂NPs were synthesized using sol–gel method. Eight male rats were specified as control non-obese. Twenty-four Wistar adult male rats were subjected to high fat diet /sucrose and they were divided into 3 groups; obese, 15 or 30 mg.kg⁻¹ CeO₂NPs IP treatment for the subsequent 8 weeks. Blood cell counts, hepicidin gene expression in adipose tissue, inflammatory and oxidative stress parameters beside iron parameters were evaluated in the experimental groups.</div></div><div><h3>Results</h3><div>CeO₂NPs crystallite size is 48.88 nm. The ratio of Ce⁴⁺ was 69.33 %. The intraperitoneal injection of obese rats with CeO₂NPs substantially reduced the elevetion in WBCs, platelets count, plasma cholesterol, triglycerides, malondialdehyde (MDA), superoxide dismutase (SOD), TNF-α (Tumor necrosis factor alpha), IL-6 (Interleukin-6), and CRP (C-reactive protein) levels. Also, CeO₂NPs combate the increase of hepcidin gene expression, ferritin level, iron content in adipose tissue, body weight, body mass index (BMI) and plasma leptin concentration of obese rats. Moreover, RBCs and WBCs count, Hb level, adiponectin level, and reduced glutathione (GSH) were enhanced in obese rats given CeO₂NPs.</div></div><div><h3>Conclusion</h3><div>CeO₂NPs may have anti-anemic activity in obese rats via management of hepcidin gene expression along with antioxidant and anti-inflammatory properties.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"14 ","pages":"Article 100260"},"PeriodicalIF":0.0,"publicationDate":"2025-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144988825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global lead contamination in soils, sediments, and aqueous environments: Exposure, toxicity, and remediation","authors":"Pratibha Mishra ,&nbsp;Shakir Ali ,&nbsp;Rakesh Kumar ,&nbsp;Shashank Shekhar","doi":"10.1016/j.jtemin.2025.100259","DOIUrl":"10.1016/j.jtemin.2025.100259","url":null,"abstract":"<div><h3>Background</h3><div>Lead (Pb) is a heavy meta(loid) and historically been used in paints, jewelleries, electronics, soldering, plumbing, and cookware due to its high malleability, low melting point, resistance to corrosion, and ability to bond with other metals. However, Pb is recognized as one of the toxic elements commonly occurring in soils, sediments, and natural water.</div></div><div><h3>Objectives and methods</h3><div>This article provides a comprehensive review of the current status of Pb contamination, underscoring its distribution, persistence, fate, and impacts on humans and plants. We investigated recent literature focusing on: <strong>(a)</strong> sources of Pb contamination in soils, sediments, and aqueous environments, <strong>(b)</strong> lead mobilization, occurrences, toxicity mechanisms, and their potential health effects; and <strong>(c)</strong> various remediation methods for Pb contamination in soil and water. Additionally, case studies from the USA, China, and India on Pb sources and pollution in different ecosystems are discussed.</div></div><div><h3>Results</h3><div>Our findings indicate that: 1) Lead concentrations exceed permissible limits in numerous soils, sediments, and water globally, while remediation efforts remain largely localized and limited in scale. 2) The mobility of Pb facilitates its bioaccumulation, enabling it to substitute for Ca²⁺ as a signalling messenger in plants and animals. This results in adverse effects such as impaired germination and nutrient uptake in plants, as well as neurotoxicity and other cascading negative impacts in humans and animals.</div></div><div><h3>Conclusion</h3><div>The study reveals that soils, sediments, and aqueous environments are moderately to highly polluted with Pb, necessitating further investigation into its mobilization and toxicity. Therefore, this contaminant should be comprehensively studied and mitigated through appropriate policy interventions.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"14 ","pages":"Article 100259"},"PeriodicalIF":0.0,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interactive effect of copper and nickel on juveniles of tambaqui (Colossoma macropomum) exposed to pH 4 and pH 7","authors":"Priscylla M. Pavione,&nbsp;Adalberto L. Val","doi":"10.1016/j.jtemin.2025.100257","DOIUrl":"10.1016/j.jtemin.2025.100257","url":null,"abstract":"<div><div>Copper (Cu) and nickel (Ni) are common in natural waters and can be toxic to fish, including those in the Amazon. The objective of this study is to assess the impact of copper (Cu) and nickel (Ni) on the biochemical and physiological characteristics of juvenile <em>Colossoma macropomum</em>. The study exposed 64 animals to varying concentrations of Cu and Ni, as well as a mixture of both metals, at pH levels of 4 and 7 for 96 h. The results demonstrated that pH levels significantly impacted several biological markers, including hemoglobin, catalase, lipoperoxidation (LPO), superoxide dismutase (SOD), and acetylcholinesterase (AChE). In particular, pH 7 was found to increase LPO and catalase levels while decreasing SOD and AChE levels. Notably, the study identified an inverse relationship between LPO levels and AChE activities. Exposure to Cu and Cu+Ni mix resulted in the inhibition of H⁺-ATPase activity at pH 4. At pH 4, Cu and Cu+Ni mix also inhibited Na⁺/K⁺-ATPase activity, while at pH 7, Ni and Cu+Ni mix inhibited it. The antagonistic effect of Ni and Cu on Na⁺/K⁺-ATPase was confirmed in animals exposed to a Cu+Ni mix. In all experimental conditions, superoxide dismutase (SOD) activities exhibited an increase at pH 4, which was followed by a decrease in lipid peroxidation (LPO). The effects of metals on SOD, LPO, and ACHE were found to be offset by changes in water pH.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"13 ","pages":"Article 100257"},"PeriodicalIF":0.0,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144828965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of pond water quality and human health risk in the shoreline, intermediate and inland coastal areas of Bangladesh","authors":"Md. Shohel Khan ,&nbsp;Shitangsu Kumar Paul","doi":"10.1016/j.jtemin.2025.100256","DOIUrl":"10.1016/j.jtemin.2025.100256","url":null,"abstract":"<div><h3>Introduction</h3><div>Surface water quality of the southwestern coastal zones of Bangladesh has been deteriorating through different human, industrial and agricultural activities. The emission of the effluents containing trace metals from these activities can contaminate the surface water. Human health may be adversely affected through the intake of trace metals present in drinking water.</div></div><div><h3>Objectives</h3><div>The study assessed pond water quality and human health risk in three villages named shoreline (Rajoir), intermediate (Gangarampur) and inland (Ganapatipur) of southwest coastal Bangladesh. A total of 36 water samples were collected from randomly selected 12 stations covering almost the entire study area. A total of 18 parameters were tested to determine the quality through water quality index (WQI), metal evaluation index (MEI), metal pollution index (MPI), and hazard index (HI). In addition, a total of 338 household heads (HHs) were interviewed through a self-developed semi-structured questionnaire along with three focus group discussions (FGDs) to achieve the objectives.</div></div><div><h3>Results</h3><div>The mean WQI increased from 105.95–150.69 from the shoreline to the inland area and was graded as ‘unsuitable’. The mean MEI was higher in the intermediate than that of shoreline and inland areas. The mean HI_child was also higher than HI_infant and HI_adult in the three study areas, indicating that children were at higher risk rather than other. The MEI results indicated that about 50 % of water samples were graded as ‘moderately affected’ for all the study area. According to MPI, about 75 % (inland) and 50 % (shoreline) water samples were graded as ‘moderately affected’. HI recommended that all the sampling stations were graded as ‘unsafe’ except 25 % of samples from both shoreline and intermediate areas for infants. The majority of the respondents reported suffering from various diseases.</div></div><div><h3>Conclusion</h3><div>Pond water is recommended for use in drinking or household purposes only after proper filtration. Furthermore, the research findings are important for environmental and human health. Further research would be beneficial to explore the link among water pollution, human health, and livelihoods, and to understand the extent of pollution. This study also serves as a baseline for the coastal area of Bangladesh.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"13 ","pages":"Article 100256"},"PeriodicalIF":0.0,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144665630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genotoxic effects of green-synthesized silver nanoparticles on human lymphocytes","authors":"Juana Sánchez-Alarcón ,&nbsp;Mirta Milić ,&nbsp;Stefano Bonassi ,&nbsp;María Isabel Álvarez Núñez ,&nbsp;Guillermo Alejandro Higareda Campos ,&nbsp;Eder José Ordoñez-Frías ,&nbsp;Rafael Valencia-Quintana","doi":"10.1016/j.jtemin.2025.100255","DOIUrl":"10.1016/j.jtemin.2025.100255","url":null,"abstract":"<div><div><strong>Background/Introduction:</strong> Silver nanoparticles (AgNPs) are widely used across various fields, particularly in biomedicine, owing to their unique physicochemical properties. Nevertheless, concerns persist regarding their potential adverse biological effects, especially genotoxicity. Although the toxicity of AgNPs has been previously investigated, studies on their genotoxic potential remain limited and yield conflicting results. <strong>Methods:</strong> This study employed the alkaline comet assay to evaluate the genotoxic potential of green-synthesized AgNPs in cultured human lymphocytes. The green-synthesized AgNPs were produced through a green reduction method using silver nitrate (AgNO₃, Reasol®, 99.98% purity) and green tea infusions (Lagg’s®), with synthesis monitored by colorimetry. Nanoparticle characterization was performed using UV-Vis spectrophotometry and Scanning Electron Microscopy (SEM), confirming their formation, stability, spherical morphology, and size range of 20 to 100 nm. Peripheral blood lymphocytes from three healthy donors were exposed to three different concentrations of green-synthesized AgNPs for 30 minutes. <strong>Results:</strong> The green-synthesized AgNPs induced DNA damage in a concentration-dependent manner, with a statistically significant increase in genotoxic effects. These findings suggest that green-synthesized AgNPs may cause oxidative stress and compromise genetic integrity. <strong>Conclusions:</strong> While green synthesis offers environmental advantages, the observed genotoxic effects raise important concerns regarding the biological safety of green-synthesized AgNPs. Further research is needed to elucidate their long-term health and environmental implications. Ongoing monitoring of products containing these nanoparticles is recommended to mitigate potential genotoxic risks.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"13 ","pages":"Article 100255"},"PeriodicalIF":0.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144580667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solanum lycopersicum exerts cardioprotective effects via reduced creatinine kinase myocardial band and ATPase activities in Wistar rats exposed to lead acetate","authors":"Olorunsola Israel Adeyomoye ,&nbsp;Olugbemi Tope Olaniyan ,&nbsp;Juliana Bunmi Adetunji ,&nbsp;Oluwaseun Charles Adetunji","doi":"10.1016/j.jtemin.2025.100253","DOIUrl":"10.1016/j.jtemin.2025.100253","url":null,"abstract":"<div><h3>Background</h3><div>Lead exposure is a known risk factor for cardiovascular diseases, yet effective cardioprotective interventions remain inadequately explored. Despite existing research, there is limited clarity on potential natural therapies that can mitigate lead-induced cardiac damage.</div></div><div><h3>Objective</h3><div>This study investigates the cardioprotective effects of ethyl acetate extract of <em>Solanum lycopersicum</em> (EESL) in lead-exposed Wistar rats, providing insights into its therapeutic potential and relevance.</div></div><div><h3>Methods</h3><div>Fresh fruits of <em>Solanum lycopersicum</em> (tomatoes) were air-dried, ground, concentrated, and extracted using ethyl acetate. A portion of EESL was analyzed using GC–MS. Fifteen (15) male Wistar rats were randomly assigned to three groups (<em>n</em> = 5 per group): control (distilled water), lead acetate (0.5 mg.mL^-1), and lead acetate + EESL (5 mg.kg^-1). Lead acetate and EESL were administered via drinking water and oral gavage, respectively, for four weeks. Body weight and lead concentration were measured using a weighing scale and flame atomic absorption spectrometry, respectively. Antioxidants and cardiac biomarkers were assessed using spectrophotometry. Data were analyzed using ANOVA at a significance level of <em>p</em> &lt; 0.05.</div></div><div><h3>Results</h3><div>Gas chromatography mass spectrometry identified 56 constituents, with 6-dehydroprogesterone (-9.3 kcal/mol) showing the highest docking affinity for the beta-adrenergic receptor. There was a significant increase in body weight in the lead acetate + EESL group compared to the lead acetate group. Lead concentration was significantly higher in the lead acetate group compared to the lead acetate + EESL group. SOD activity significantly increased in the lead acetate + EESL group, while CK-MB, Na⁺/K⁺ ATPase, and Ca²⁺ ATPase activities significantly decreased compared to the lead acetate group.</div></div><div><h3>Conclusion</h3><div><em>Solanum lycopersicum</em> ethyl acetate extract demonstrated cardioprotective effects by enhancing antioxidant activity and reducing cardiac injury markers in lead-exposed rats. However, the associated increase in body weight raises concerns about potential metabolic risks, warranting further investigation</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"13 ","pages":"Article 100253"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144296935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}