Journal of trace elements and minerals最新文献

{"title":"Assessment of borehole water quality in Nwadzekudzeku village, Giyani, Limpopo Province, South Africa: Implication for potential human health risks","authors":"Tsakane Patience Maluleke,&nbsp;Sifelani Dube,&nbsp;Emmanuel Daanoba Sunkari,&nbsp;Abayneh Ataro Ambushe","doi":"10.1016/j.jtemin.2024.100206","DOIUrl":"10.1016/j.jtemin.2024.100206","url":null,"abstract":"<div><h3>Introduction</h3><div>Due to a lack of potable water supplies in rural areas of South Africa, most rural communities depend on groundwater for subsistence. Concerns have been raised about the quality of Nwadzekudzeku village borehole water.</div></div><div><h3>Methods</h3><div>This study investigated physicochemical parameters, anions and potentially toxic elements (PTEs) in drinking water to evaluate the borehole water quality from Nwadzekudzeku village. A multi-methods approach involving water quality analysis, geospatial mapping, multivariate statistical analysis, and human health risk analysis were employed in this study.</div></div><div><h3>Results and Discussion</h3><div>The results showed that borehole water had a pH ranging from 6.96 - 7.76, an electrical conductivity (EC) of 132 - 2740 µS.cm⁻¹, total dissolved solids (TDS) of 381 - 1336 mg.<em>L</em>⁻¹, resistivity in the range of 62 - 1030 Ω, salinity from 0.32 - 1.34 ppt and an oxidation–reduction potential (ORP) of 9.20 - 233 mV. Most borehole water samples were found to have all physicochemical parameters above the maximum permissible levels (MPLs) set by the World Health Organization (WHO) and South African National Standards (SANS) except for pH and temperature. Concentrations of anions were determined in the mg.<em>L</em>⁻¹ range with Cl⁻ (44.0 – 853 mg.<em>L</em>⁻¹) and NO₃⁻ (25.0 – 127 mg.<em>L</em>⁻¹) as the only anions above WHO and SANS stipulated limits for drinking water. The results of cations showed that Na is the dominant cation with concentrations ranging from 42.8 – 241 mg.<em>L</em>⁻¹, which exceed the WHO MPL. Based on the cation and anion dominance in the borehole water, the water is predominantly Na-Cl water type. The concentrations of PTEs in water were within the MPLs set by WHO. Multivariate statistical analysis revealed that the hydrochemical parameters were enriched in the aquifer through ion exchange reaction, dissolution of silicate minerals from the mafic-ultramafic lithologies, and agricultural activities. Children are the hypersensitive population with respect to nitrate toxicity in water as they show cumulative hazard index (HI) values ranging from 0.02 - 6.59 with an average value of 2.49, whereas HI for adults ranged from 0.02 - 4.71 with an average value of 1.78.</div></div><div><h3>Conclusion</h3><div>This suggests that there is a high non-carcinogenic risk in the Nwadzekudzeku village because of the concentration of nitrate, as indicated by the average cumulative HI for children and adults being higher than the recommended value of 1.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"11 ","pages":"Article 100206"},"PeriodicalIF":0.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143153436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of nutrients on the growth and quality of medicinal and aromatic plants, affecting athletic abilities","authors":"Mohammad Miransari,&nbsp;Shirin Adham,&nbsp;Mahdiar Miransari,&nbsp;Amir Arshia Miransari","doi":"10.1016/j.jtemin.2024.100205","DOIUrl":"10.1016/j.jtemin.2024.100205","url":null,"abstract":"<div><h3>Background</h3><div>Although the use of medicinal and aromatic plants (herbs and fruits) has become popular, worldwide, more has yet to be indicated on their applications, due to their significance from economic and health aspects. Medicinal and aromatic plants are used for treating diseases and improving the nutrition and health of people including athletes.</div></div><div><h3>Objectives and methods</h3><div>It is accordingly pertinent to find and use methods, which may improve growth and biochemical properties of medicinal and aromatic plants. The objective was to investigate how macro- and micro-nutrients may effectively enhance the quantity and quality of medicinal and aromatic plants by regulating plant biochemical properties (production of secondary metabolites) and increasing plant growth and quality in different conditions including stress. This may also be of significance for the athletic activities.</div></div><div><h3>Results</h3><div>High number of related research and review articles were consulted, which indicated medicinal and aromatic plants and chemical supplements can be used to promote athletes' health and improve their athletic performance. This investigation also revealed that the production of free radicals during exercise may unfavorably affect athletes' health, however, the use of medicinal and aromatic plants may be a favorite method to diminish such unfavorite effects and enhance athletes' health. The use of soil microbes may also enhance the growth and physiology of medicinal and aromatic plants in different conditions by enhancing plant nutrient uptake and subsequent alleviation of stress.</div></div><div><h3>Conclusion</h3><div>In the present review the most recent research about the effects of nutrients on the growth and physiological properties of medicinal and aromatic plants and their subsequent effects on the athletes' health have been reviewed and analysed. Planning a suitable nutritional strategy for the athletes using chemical supplements and medicinal and aromatic plants can significantly improve their performance. The review can be beneficial for promoting people's health including athletes in the society, which is also of economic significance as it may decrease the expenses spent for medical treatment in the society.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"11 ","pages":"Article 100205"},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143153439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appraisal of pollution, ecological and health risks assessment of trace metals in soils of Logbadjeck quarrying area, Nyong Series, Cameroon","authors":"Anicet Feudjio Tiabou ,&nbsp;Guy Amie Atabe Atabe ,&nbsp;Cyrille Sigue ,&nbsp;Lemnyuy Prosper Yiika ,&nbsp;Fatemeh Kachoueiyan ,&nbsp;Nkeng Enstein Forchenallah","doi":"10.1016/j.jtemin.2024.100204","DOIUrl":"10.1016/j.jtemin.2024.100204","url":null,"abstract":"<div><h3>Background</h3><div>Assessing toxic metals in agricultural soils or farmlands is a worldwide concern for maintaining ecosystem health, especially in developing countries such as Cameroon. Therefore, this study examines the contamination levels and the ecological and health risks of trace metals in the soils of the Logbadjeck quarrying area.</div></div><div><h3>Methods</h3><div>Soil samples from the Logbadjeck quarrying area were examined using Inductively Coupled Plasma-Mass Spectrometry (ICP-MS).</div></div><div><h3>Results and discussion</h3><div>The findings of this research show that trace metals in soils examined significantly exceeded the permissible limit. Correlation matrix and principal component analysis suggest similar provenance of trace metals. A low to moderate level of contamination was found using the geo-accumulation index, ecological risk index, and contamination factor. Logbadjeck soils had minimal pollution levels, as indicated by most stations with pollution load index values &lt; 1 and Nemerow integrated pollution index values of 1–2. The ecological and toxic risk index shows negligible ecological risk and no toxic risk levels of trace metals. The health risk assessment's findings showed that while accidental ingestion and skin contact with trace metals in soils exposed recreational receptors to carcinogenic and non-carcinogenic risks, it was necessary to implement policies and undertake remediation to control the elevated carcinogenic risks of Cr, Ni, and Pb in soil. This study's data offers profound insights into our knowledge of environmental contaminants and their potentially harmful impacts in the study area.</div></div><div><h3>Conclusion</h3><div>The soils of the Logbadjeck quarrying area are in the low to moderate contamination category due to geogenic influences and anthropogenic practices. It is recommended that ongoing soil and agricultural products be monitored to avoid trace metal concentrations from anthropogenic practices in the food chain rising above permissible bounds and safeguard the health of humans and animals in the research region.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"10 ","pages":"Article 100204"},"PeriodicalIF":0.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elemental profiling of the root samples of six species of the genus Sida L","authors":"G Ashwathy,&nbsp;Krishnakumar K","doi":"10.1016/j.jtemin.2024.100201","DOIUrl":"10.1016/j.jtemin.2024.100201","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Sida</em> L. is a medicinally important genus comprising many species used in the traditional systems of medicine in different parts of the world. The present study deals with the elemental analysis of the root samples of six species of <em>Sida</em> L. viz.<em>, S. alnifolia</em> L., <em>S. beddomei</em> Jacob.<em>, S. fryxelli</em> Sivar. &amp; Pradeep.<em>, S. rhomboidea</em> Roxb. ex. Flemming.<em>,</em> and <em>S. keralensis</em> E. S. S. Kumar, Shailaja, Sreekala, Parthipan &amp; R. Prakashkumar sp. <em>nov</em>.</div></div><div><h3>Materials and methods</h3><div>Field explorations were carried out in Kerala, India, and root samples of different species were collected, shade-dried, and powdered. The powdered root samples of each species were analyzed using Atomic Absorption Spectrophotometer (AAS), and Flame Photometer.</div></div><div><h3>Results</h3><div>The presence of Sodium (Na), Potassium (K), Calcium (Ca), Magnesium (Mg), Iron (Fe), Zinc (Zn), Manganese (Mn), Copper (Cu), Cadmium (Cd), Chromium (Cr), Nickel (Ni), and Lead (Pb) were detected in the species of <em>Sida</em> L. under study. The most abundant macro-element was detected as K, ranging from 15,630±0.21 mg kg⁻¹ in <em>S. rhomboidea</em> to 24,910±0.14 mg kg⁻¹ in <em>S. beddomei</em>. Among the micro-elements, Fe was present in higher concentrations ranging from 461.7 ± 193.96 mg kg⁻¹ in <em>S. cordata</em> to 1363.93±192.90 mg kg⁻¹ in <em>S. beddomei.</em> Toxic metals like Cr, Cd, Ni, and Pb were below detectable levels.</div></div><div><h3>Conclusion</h3><div>The elemental composition of the species under study was quite different but within the permissible limits recommended by WHO. The current study revealed that the species of <em>Sida</em> L. under study could be valuable for Ayurvedic practitioners and traditional healers in developing herbal formulations.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"10 ","pages":"Article 100201"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing metals and metalloids impact of roadside dust on human health in Osogbo, Osun state, Nigeria","authors":"A.O. Aturamu ,&nbsp;O Asaolu ,&nbsp;O.J. Ademuyiwa","doi":"10.1016/j.jtemin.2024.100202","DOIUrl":"10.1016/j.jtemin.2024.100202","url":null,"abstract":"<div><h3>Background</h3><div>Metals and metalloids in roadside dust pose considerable threats to both human health and the environment.</div></div><div><h3>Objectives</h3><div>This study assesses human health risks of metal exposure to roadside dust by conducting a health risk assessment (HRA) for metals and metalloids uptake rates for children and adults via exposure pathways.</div></div><div><h3>Methods</h3><div>Settled dust samples were collected from the major roads in Osogbo, Osun state. These samples were subjected to standard laboratory procedures for metals and metalloids analysis using Atomic Absorption Spectroscopy (AAS).</div></div><div><h3>Results</h3><div>All the metals and metalloids except Cd had their concentration below the WHO limit. The average concentration of Cd was 1.54 mg kg-1, significantly above the WHO guideline of 0.80 mg kg-1, indicating a possible health concern. A strong positive correlation exits between Ni and Cd (0.774^⁎⁎) (<em>p</em> &lt; 0.01), Pb (0.662^⁎⁎) (<em>p</em> &lt; 0.01), Zn (0.606^⁎⁎) (<em>p</em> &lt; 0.01), and as (0.549*) (<em>p</em> &lt; 0.05), showing that greater Ni concentrations are associated with higher concentrations of Cd, Pb, Zn, and As. Two principal components were identified, accounting for 80 % of the overall variation. PC1 has an eigenvalue of 60.834; however, PC2 has a higher eigenvalue of 74.952, implying that PC2 explains more of the variation in the data than PC1. Non-carcinogenic risk evaluations identify possible health risks linked with Cu, Cd, Cr, and As exposure, primarily through inhalation routes. Carcinogenic risk showed that Cd demonstrated high CR values ranging from 3740 to 1.30×10¹² for adults and children throughout the study's various exposure paths.</div></div><div><h3>Conclusion</h3><div>This study offered significant insight into the metals and metalloids pollution status in Osogbo, Nigeria, employing data and statistics, highlighting the need for evidence-based actions for environmental preservation to safeguarding people's health.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"10 ","pages":"Article 100202"},"PeriodicalIF":0.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142656710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macromineral, micromineral and metal concentration of bovine colostrum samples from Salzburg, Austria","authors":"Katharina Lichtmannsperger ,&nbsp;Nicole Hechenberger ,&nbsp;Ariane Psenner ,&nbsp;Maren Marseiler ,&nbsp;Andrea Hildebrand ,&nbsp;Elisabeth Müller ,&nbsp;Alexander Tichy ,&nbsp;Thomas Wittek","doi":"10.1016/j.jtemin.2024.100203","DOIUrl":"10.1016/j.jtemin.2024.100203","url":null,"abstract":"<div><h3>Background</h3><div>Besides immunoglobulins which are essential for the calf to prevent Failure of Transfer of Passive Immunity (FTPI) colostrum contains multiple other constituents such microminerals, macrominerals and metals. The concentration of the minerals seems to be higher in colostrum than in normal milk. The aims of this study were to describe macromineral, micromineral and metal concentration of bovine colostrum samples from Salzburg, Austria and to see if there are differences in the concentrations between different cow feeding strategies and farm locations.</div></div><div><h3>Methods</h3><div>Therefore, 1050 individual colostrum samples were collected from 72 dairy farms from different districts of Salzburg. All colostrum samples were analysed for macromineral (K, Mg, Na), micromineral (Co, Cu, Fe, I, Mg, Se, Zn) andmetal (As, Ba, Cd, Li, Mo, Ni, Pb, Sr, Tl, U) concentrations by inductive coupled plasma mass spectrometry.</div></div><div><h3>Results</h3><div>The mean K, Mg and Na levels were 1218.71 mg l^-1, 245.44 mg l^-1 and 358.62 mg l^-1, respectively. The micromineral concentrations of I, Se, Co and Zn were significantly higher in colostrum from dairy cows feeding a Total-Mixed-Ration during the lactation period in comparison to cows receiving microminerals by hand feeding, transponder feeding or via a licking bucket or licking stone. The metal analysis showed that in three farms, most of the colostrum samples showed Pb levels above the limit of 5 µg l^-1.</div></div><div><h3>Implications</h3><div>Herd-level factors need to be addressed to elevate micromineral concentrations and to reduce metal concentrations in colostrum from dairy cows from Salzburg, Austria.</div></div><div><h3>Conclusion</h3><div>The results show that the macrominerals K, Mg and Na are within the range of published concentrations. For the microminerals, Co, Cu, Fe, I, Mg, Se and Zn the concentrations were significantly different depending on the mineral feeding strategies during the lactation and dry period. Metal concentrations of As, Ba, Cd, Li, Mo, Ni, Pb, Sr, Tl and U differed between the districts of Salzburg.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"10 ","pages":"Article 100203"},"PeriodicalIF":0.0,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial for the virtual special issue (VSI) “metal and metalloid contamination in soil and vegetables”","authors":"Sidney Fernandes Sales Júnior ,&nbsp;Enrico Mendes Saggioro","doi":"10.1016/j.jtemin.2024.100198","DOIUrl":"10.1016/j.jtemin.2024.100198","url":null,"abstract":"<div><h3>Background</h3><div>Industrial growth and population expansion have led to increasing contamination of soils and plants by metals and metalloids. Toxic elements such as lead, cadmium, and arsenic persist in the environment, presenting significant risks to both ecosystems and human health. This editorial introduces the Virtual Special Issue, which compiles recent studies on the infiltration of these contaminants into soils and their bioaccumulation in plants.</div></div><div><h3>Objectives</h3><div>This special issue aims to explore the interaction between human activities and metal/metalloid contamination, highlight key bioaccumulation mechanisms, transfer dynamics, and assess the risks posed to human health by contaminated soils and plants.</div></div><div><h3>Methods</h3><div>The contributions to this issue include a variety of methodologies, both in laboratory and field settings, such as soil contamination assessments, bioaccumulation studies in plant species, and risk estimations for human exposure.</div></div><div><h3>Results</h3><div>The compiled studies demonstrate significant contamination levels in soils and plants, especially in regions of Africa and Asia, where cadmium, mercury, zinc, and arsenic frequently exceed safety guidelines. These findings emphasize the urgent need for stricter contamination controls and further investigation in underrepresented regions.</div></div><div><h3>Conclusion</h3><div>This issue provides crucial insights into metal and metalloid contamination in agricultural systems, offering evidence that can inform environmental policies and support the development of sustainable agricultural practices to mitigate contamination risks.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"10 ","pages":"Article 100198"},"PeriodicalIF":0.0,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142537800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced antibacterial effect of natural tannin stabilized silver nano particles against human pathogens: A target toward FtsZ proteins","authors":"Ishita Biswas ,&nbsp;Debanjan Mitra ,&nbsp;Soumitra Das ,&nbsp;Devbarni Sarkar ,&nbsp;Pradeep K. Das Mohapatra","doi":"10.1016/j.jtemin.2024.100200","DOIUrl":"10.1016/j.jtemin.2024.100200","url":null,"abstract":"<div><h3>Background</h3><div>Tannins are the polyphenolic group of plant compounds having strong antimicrobial potential. Research on human pathogens using silver nanoparticles for antimicrobial purposes has opened up new possibilities in nanomedicine.</div></div><div><h3>Objective</h3><div>The present study was concerned with combining the effectiveness of the two by the green synthesis of silver nanoparticles with plant tannin.</div></div><div><h3>Methods</h3><div>Synthesis of silver nanoparticles was done based on the tannin content of the selected plants. Characterization of the synthesized nanoparticles has been performed through UV–VIS, FTIR spectroscopy, Zeta potential, XRD analysis and FEGSEM imaging. The antibacterial potentiality of the nanoparticles was checked against two most susceptible bacteria <em>Staphylococcus epidermidis</em> and <em>Salmonella typhi</em>.</div></div><div><h3>Results</h3><div>Among the studied plants, <em>Phyllanthus emblica</em> showed highest tannin content and best bactericidal properties. The nanoparticles synthesized with <em>P. emblica</em> showed the highest zone of inhibition against the studied bacteria. An in-silico comparative molecular docking study of the bioactive compounds from the selected plants was performed against the FtsZ protein of <em>S. epidermidis</em> and YfdX protein of <em>S. typhi.</em> Three compounds namely Isocorilagin,1(β), 6-di-o-galloylglucose and Hamamelitannin appeared as the best inhibitors of the said proteins and among them, Isocorilagin, a natural tannin showed the best docking score of -10.2 Kcal/mol with FtsZ protein. Further molecular dynamics simulation studies of the FtsZ protein-Isocorilagin complex support its stability indicating Isocorilagin as the natural inhibitor of the pathogenic bacterial protein FtsZ.</div></div><div><h3>Conclusion</h3><div>These results concluded that synthesis of nanoparticles with plant tannin is a cost effective green approach and the synthesised nanoparticles appear as efficient antimicrobial agent.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"10 ","pages":"Article 100200"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142420583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatotoxicity induced by subacute exposure of Mancozeb and Arsenic in Wistar rats: Mitigating effect of quercetin and catechin","authors":"Rasia Yousuf ,&nbsp;Pawan Kumar Verma ,&nbsp;Priyanka Sharma ,&nbsp;Shilpa Sood ,&nbsp;Nrip K. Pankaj ,&nbsp;Zuhaib F. Bhat","doi":"10.1016/j.jtemin.2024.100199","DOIUrl":"10.1016/j.jtemin.2024.100199","url":null,"abstract":"<div><h3>Background</h3><div>Widespread use of Mancozeb (MZ) fungicide in endemic areas having high levels of arsenic (As⁺³) in the groundwater is likely to cause toxicosis in humans and animals. Therefore, the present study aimed to determine the hepatotoxic effect of MZ and As⁺³ interaction in Wistar rats and mitigating potential of quercetin and catechin on such toxicity.</div></div><div><h3>Methods</h3><div>Sixty adult rats were randomly divided into 10 groups of 6 animals each. Group I served as control and group II was exposed to MZ (800 mg kg^-1, PO). Groups III, IV, and V were provided drinking water containing As⁺³ at the rate of 10, 50 and 100 µg L^-1, respectively. Groups VI, VII, and VIII were given drinking water containing As⁺³ at 10, 50 and 100 µg L^-1, respectively, along with MZ. Groups IX and X received drinking water contaminated with 100 µg L^-1, As⁺³ and MZ along with quercetin or catechin (50 mg kg^-1 each), respectively.</div></div><div><h3>Results</h3><div>Significant (p &lt;0.05) alterations in hepatic biomarkers in blood, liver antioxidant status and hepatic histoarchitecture were observed in animals treated with individual toxicants in a dose-dependent manner, however, such toxicity-induced changes were more severe in co-exposed rats. The administration of quercetin or catechin significantly mitigated the dual toxicant administration-driven changes in biochemical markers of hepatic damage, hepatic antioxidant profile and liver histomorphology.</div></div><div><h3>Conclusions</h3><div>Both quercetin and catechin proved beneficial in reducing toxicant-induced oxidation-mediated hepatic damage as demonstrated by alleviation in altered levels of determinants of hepatic biochemical and oxidative stress parameters in addition to restoration of toxicant-induced histological alterations of hepatic tissue.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"10 ","pages":"Article 100199"},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142440904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnesium involvement in social behavior and in the treatment of some psychological disorders. A review","authors":"Mihai Nechifor","doi":"10.1016/j.jtemin.2024.100194","DOIUrl":"10.1016/j.jtemin.2024.100194","url":null,"abstract":"<div><h3>Background</h3><div>Social behavior is generally defined as all behavior that influences, or is influenced by, other members of the same species. This behavior is essential for social life and the evolution of society. Numerous factors influence this behavior. One of the factors that are important for social behavior and that modulates many of the neural mechanisms involved in the production of social behavior is formed by magnesium (Mg) and other bivalent cations in the brain.</div></div><div><h3>Methods</h3><div>In this review, the results of some articles included in the international databases were used.</div></div><div><h3>Results</h3><div>Mg has an essential modulating role for a large part of the elements that are part of social behavior such as: aggression, memory and cognition, eating behavior, addictions and others. Memory disorders, cognition, all forms of addiction are important psychiatric diseases, but they also have a strong impact on social behavior. The main mechanisms by which Mg is involved in social behavior are: the modulation of the presynaptic release of some brain neurotransmitters, synaptic neuroplasticity, the modification of the affinity of some neuronal receptors for their agonists, the transduction of the biological signal after stimulating the receptors, the activity of some neuronal enzymes. Magnesium decreases intraspecific and interspecific aggression, improves memory and eating behavior, reduces the intensity of addictions and the vulnerability of people at risk of becoming addicted, improves attention deficit in children and reduces anxiety.</div></div><div><h3>Conclusions</h3><div>Correcting the high frequency of chronic Mg deficiency in today's society is strictly necessary and must be done as soon as possible. This normalization of the Mg level improves many of the elements of social behavior. Prevention and correction of Mg deficiency reduce the risk of developing serious diseases such as depression, addictions,memory disordres, anxiety states and other. The association of Mg with the drugs used to treat these diseases can be beneficial.</div></div>","PeriodicalId":73997,"journal":{"name":"Journal of trace elements and minerals","volume":"10 ","pages":"Article 100194"},"PeriodicalIF":0.0,"publicationDate":"2024-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142322919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}