Journal of mother and child最新文献

{"title":"Epidemiological, Clinical, and Laboratory Features of Children with SARS-CoV-2 in Ukraine.","authors":"Tetiana Harashchenko, Tetiana Umanets, Volodymyr Podolskiy, Tetiana Kaminska, Yuriy Marushko, Vasily Podolskiy, Volodymyr Lapshyn, Yurii Antypkin","doi":"10.34763/jmotherandchild.20232701.d-23-00012","DOIUrl":"10.34763/jmotherandchild.20232701.d-23-00012","url":null,"abstract":"<p><strong>Introduction: </strong>In December 2019, the Chinese city of Wuhan reported the first cases of pneumonia from a new type of beta coronavirus named SARS-CoV-2. In the early days of the COVID-19 outbreak, paediatric patients were thought to be immune to the new virus; however, further studies have shown people of all ages to be susceptible to the virus.</p><p><strong>Objective: </strong>Identify and describe the clinical and epidemiological features of COVID-19 among hospitalized children in Ukraine.</p><p><strong>Materials and methods: </strong>Retrospective study of 171 children aged 2 months to 18 years who were hospitalized with laboratory-confirmed SARS-CoV-2.</p><p><strong>Results: </strong>Most patients in the study had a moderate progression of the disease (77.78%, or n=133), whereas a severe course was noted in 22.22% (n=38). Across age groups, children aged 6-12 was the predominant age group affected (35.67%, or n=61). The most common symptoms were fever in 88.2% of patients, sore throat in 69.2% and cough in 60.9%. Symptoms associated with dyspnoea and cyanosis were significantly more common in children with the severe course (p<0.05). Almost half of children had at least one comorbidity, the most prevalent being chronic tonsillitis (11.8% of patients) and anemia (6.5% of patients). A positive correlation (r=0.7 p<0.05) was found between CRP levels and COVID-19 severity. X-ray changes in the lungs were present in 76.61% of examined children and ground-glass opacity symptom was registered in 50.88%.</p><p><strong>Conclusions: </strong>COVID-19 among hospitalized children in Ukraine usually has a moderate course of illness and a good prognosis.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"27 1","pages":"33-41"},"PeriodicalIF":0.0,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10503458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and Determinants of Non-Utilization of Modern Contraception in Ekiti State, Nigeria: A Ten-Year Review.","authors":"Oluwafunmilayo Oluwadamilola Ibikunle, Tope Michael Ipinnimo, Ayobami Oyekunle Afape, Austine Idowu Ibikunle, Caroline Ajoke Bakare, Babatunde Ajidagba, Demilade Olusola Ibirongbe, Esther Opeyemi Ajidahun, Kabir Adekunle Durowade, Adebowale Femi Akinwumi, Ayokunle Faniku, Babatunde Adelekan","doi":"10.34763/jmotherandchild.20232701.d-22-00067","DOIUrl":"10.34763/jmotherandchild.20232701.d-22-00067","url":null,"abstract":"<p><strong>Background: </strong>An increase in correct usage of modern contraception is vital in reducing the maternal mortality ratio and Under-5 mortality, leading towards the achievement of Sustainable Development Goal 3. Our study examined the trends and factors affecting non-utilization of modern contraceptives over a 10-year period in Ekiti State, Nigeria.</p><p><strong>Methodology: </strong>This study used data from three consecutive National Demographic Health Surveys (NDHS) - 2008, 2013, and 2018 - with a weighted sample size of 1,357 women of reproductive age (15-49 years). Data on contraceptive use on these women, provided by the NDHS, were extracted and analysed using IBM SPSS version 25. The sample was weighted to adjust for disproportionate sampling and non-response. Pearson's chi-square and binary logistic regression were used to assess the factors associated with non-utilization of modern contraceptives.</p><p><strong>Results and findings: </strong>The mean age of the women was 30 years. Modern contraceptive use increased from 13.1% in 2008 to 23.0% in 2018, while unmet need for modern contraceptives decreased from 84.8% in 2008 to 75.4% in 2018. Identified predictors of non-utilization of modern contraceptive were age 20-24 years [aOR=0.33, 95%CI=0.19-0.59], 25-29 years [aOR=0.34, 95%CI=0.18-0.64], 30-34 years [aOR=0.46, 95%CI=0.22-0.94], 35-39 years [aOR=0.29, 95%CI=0.14-0.61] and 40-44 years [aOR=0.37, 95%CI=0.17-0.80] compared to age 15-19 years; living in urban areas [aOR=0.72, 95%CI=0.53-0.98] compared to in rural areas; higher level of education [aOR=0.46, 95%CI=0.21-0.98] compared to no education; and desire for more children [aOR=0.48, 95%CI=0.32-0.73] compared to not wanting more children.</p><p><strong>Conclusion: </strong>Although contraceptive usage increased over time, the factors associated with non-utilization were being an adolescent, living in a rural area, lower level of education, and desire for more children.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"27 1","pages":"42-51"},"PeriodicalIF":0.0,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10503457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Early Exposure to Play Materials on Motor Development in High-Risk Infants: A Randomised Controlled Trial.","authors":"Mrunmayi S Gadre, Vinuta R Deshpande","doi":"10.34763/jmotherandchild.20232701.d-22-00025","DOIUrl":"10.34763/jmotherandchild.20232701.d-22-00025","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study was to determine the impact of early exposure to play materials on motor development in high-risk infants.</p><p><strong>Materials and methods: </strong>A 1:1 parallel group randomised control study was conducted. A total of 36 participants were recruited, with 18 in each group. The intervention lasted 6 weeks for both groups, with follow-ups in the 2nd and 4th weeks. The Peabody Developmental Motor Scale 2nd Edition (PDMS-2) was used as an outcome measure. The data was analysed using the Likelihood Ratio test, Chi-square test, independent sample t-test, and paired t-test.</p><p><strong>Results: </strong>There was no difference between the groups except for the raw reflex scores (t = 3.29, p = 0.002), raw stationary scores (t = 4.26, p < 0.001), standard stationary scores (t = 2.57, p = 0.015), and Gross Motor Quotient (GMQ) (t = 3.275, p = 0.002). Statistical significance within the experimental group was observed in the raw reflex (t = -5.16, p < 0.001), stationary (t = -10.5, p < 0.001), locomotion (t = -5.67, p < 0.001), grasp (t = -4.68, p < 0.001), and visual motor (t = -5.03, p < 0.001) scores, as well as the standard stationary (t = -2.87, p = 0.010), locomotion (t = -3.43, p = 0.003), grasp (t = -3.28, p = 0.004), and visual motor (t = -5.03, p < 0.001) scores. Quotients were the GMQ (t = -7.31, p < 0.001), Total Motor Quotient (TMQ) (t = -5.71, p < 0.001), Fine Motor Quotient (FMQ) (t = -6.48, p < 0.001). Conclusions: The current study concludes that a six-week treatment of early exposure to age-appropriate toys is advantageous in enhancing motor development in high-risk neonates.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"27 1","pages":"64-71"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10148664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Covid-19 Vaccination during Pregnancy on the Obstetric and Neonatal Outcomes in a Tertiary Health Care Center.","authors":"Gargee Suman Tripathy, Tanushree Sandipta Rath, Saujanya Behera, K Shruti Lekha, Dattatreya Kar, Sujata Pendyala","doi":"10.34763/jmotherandchild.20232701.d-22-00043","DOIUrl":"10.34763/jmotherandchild.20232701.d-22-00043","url":null,"abstract":"<p><strong>Background: </strong>Pregnancy is an immuno-compromised state, and pregnant women with COVID-19 are at an increased risk for adverse pregnancy outcomes. Thus, the Center for Disease Control and Prevention (CDC) and the Advisory Committee on Immunization (ACIP) have advocated for COVID-19 vaccination in pregnant women. COVAXIN and COVISHIELD were the vaccines being used in India in the first phase of vaccination, but limited data exist on pregnancy outcomes regarding SARS-CoV-2 vaccines and pregnancy and lactation.</p><p><strong>Material and methods: </strong>A retrospective study was conducted which included only women who delivered after 24 weeks gestation. Women with an unknown vaccination status or with past or active COVID-19 infection were excluded. Demographic characteristics, maternal and obstetric outcomes, and fetal and neonatal outcomes were compared between the unvaccinated and vaccinated groups. Statistical analysis was done with Chi-square testing and the Fisher exact test using SPSS-26 software.</p><p><strong>Results: </strong>Deliveries before a gestation of 37 weeks were significantly higher in the unvaccinated group compared to the vaccinated group. Rates of vaginal deliveries and preterm deliveries were found to be higher in the unvaccinated population. Women who had taken COVAXIN had a higher rate of adverse events compared to those who had taken COVISHIELD.</p><p><strong>Conclusion: </strong>There were no significant differences in adverse obstetric outcomes attributed to vaccine administration between the vaccinated and unvaccinated pregnant women. The beneficial effects of the vaccines in protecting against COVID-19 infection, particularly in pregnancy, outweigh the minor adverse events associated with vaccine administration.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"27 1","pages":"72-78"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10521479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Review on Hot Ambient Temperature and its Impacts on Adverse Pregnancy Outcomes.","authors":"Shanmugam Rekha, Sirala Jagadeesh Nalini, Srinivasan Bhuvana, S Kanmani, Venugopal Vidhya","doi":"10.34763/jmotherandchild.20232701.d-22-00051","DOIUrl":"10.34763/jmotherandchild.20232701.d-22-00051","url":null,"abstract":"<p><strong>Introduction: </strong>High workplace/ambient temperatures have been associated with Adverse Pregnancy Outcomes (APO). Millions of women working in developing nations suffer due to the rising temperatures caused by climate change. There are few pieces of research linking occupational heat stress to APO, and fresh evidence is required.</p><p><strong>Methodology: </strong>We used databases including PubMed, Google Scholar, and Science Direct to search for research on high ambient/workplace temperatures and their effects. Original articles, newsletters, and book chapters were examined. The literature we analysed was categorised as follows: Heat, strain, and physical activity harming both mother and fetus. After categorising the literature, it was examined to identify the major results.</p><p><strong>Results: </strong>We found a definite association between heat stress and APOs such as miscarriages, premature birth, stillbirth, low birthweight, and congenital abnormalities in 23 research articles. Our work provides important information for future research into the biological mechanisms that create APOs and various prevention measures.</p><p><strong>Conclusion: </strong>Our data suggest that temperature has long-term and short-term effects on maternal and fetal health. Though small in number, this study stressed the need for bigger cohort studies in tropical developing countries to create evidence for coordinated policies to safeguard pregnant women.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"27 1","pages":"10-20"},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10146683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Oral Protein Supplementation on the Growth of Very Low Birth Weight Preterm Infants Admitted to the Neonatal Intensive Care Unit: A Randomized Clinical Trial.","authors":"Fariba Hemmati, Maral Ghassemzadeh","doi":"10.34763/jmotherandchild.20232701.d-22-00072","DOIUrl":"10.34763/jmotherandchild.20232701.d-22-00072","url":null,"abstract":"<p><strong>Background: </strong>During NICU admission, extra-uterine growth retardation that can affect the neurodevelopmental outcome is a challenging problem in extremely preterm infants. This trial aimed to determine the effect of additional enteral protein supplementation on the growth velocity of the anthropometric parameters.</p><p><strong>Method: </strong>In this randomized controlled trial, 77 preterm infants (gestational age ≤33 weeks and birth weight <1500 g) who reached full enteral feeding with either fortified breast milk or preterm formula were included. They were randomized to receive either 4-<5 g/kg/day protein through extra protein supplementation (intervention) or 3-<4 g/kg/day protein. Weight gain, as well as length and head circumference growth, were monitored daily and weekly, respectively. Venous blood gas, blood urea nitrogen (BUN), and albumin levels were checked weekly.</p><p><strong>Results: </strong>Five out of 77 participants were excluded due to feeding intolerance. Analyses were conducted on 36 neonates with protein intake of 3.66 ± 0.22 gr/kg/day and 36 with extra protein intake. Baseline characteristics were similar between the groups. An additional protein supply of 0.89 gr/kg/day, resulting in an average protein intake of 4.55 ± 0.18 in the intervention group, increased the postnatal weight gain, linear growth, and head circumference growth (7.98 gr/kg/day, 0.347 cm/week, and 0.38 cm/week, respectively). The albumin levels were significantly increased, but the BUN levels were not significantly increased in the intervention group. None of the patients developed necrotizing enterocolitis or significant acidosis.</p><p><strong>Conclusion: </strong>Protein supplementation significantly improves the growth of the anthropometric parameters. An increase in serum albumin and no increase in serum urea can indicate the anabolic effect of extra protein. Protein supplementation can add to routine feeding protocols of VLBW infants without any short-term adverse effect; however, further study for evaluation of long-term complications is needed.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"27 1","pages":"21-29"},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10146685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Menstrual Health Problems of Women Indigenous Peoples around Protected Forest Area in Sumatra, Indonesia, and Plants' Usefulness to Treat It.","authors":"Yesi Mustika Sari, N Novriyanti","doi":"10.34763/jmotherandchild.20222601.d-22-00064","DOIUrl":"10.34763/jmotherandchild.20222601.d-22-00064","url":null,"abstract":"<p><strong>Background: </strong>Some cultures have a favorable view of menstruation, consider it sacred, and respect the female body, so some local wisdom and the practice of using plant species are also attached to it. Moreover, menstruation is an integral part of reproductive health for women as mothers of a nation. However, the management of menstrual problems included in the United Nations Sustainable Development Goals (gender justice) goals in several indigenous communities around the forest has not received attention.</p><p><strong>Objective: </strong>This study aims to explain the situation of menstrual management, predict indications of reproductive problems, and record the practice of using plants to overcome these problems in indigenous tribal communities around the forest.</p><p><strong>Material and methods: </strong>A total of 15 youths of the Orang Rimba, one of the marginal indigenous people in Jambi Province, Sumatra Island, Indonesia, were the subjects of measurement of all variables using anthropometric measurement procedures. The 15 girls were also interviewed regarding menstrual problems, personal hygiene management, and using plant species to overcome them. Meanwhile, ten adults became respondents to the complementary primary data.</p><p><strong>Results: </strong>No plant species were explicitly used to treat menstrual problems. Four species are used by the Orang Rimba concerning labor management (pre- and postpartum).</p><p><strong>Conclusion: </strong>There are no significant reproductive problems despite the incidence of dysmenorrhea. However, aspects of nutrition and personal hygiene, including during menstruation, still need special attention, especially considering that the typology of Orang Rimba varies according to their Tumenggung and the characteristics of their forest habitat; It is challenging to measure their health as a group. This condition may also apply to other communities around the forest due to their limited reproductive health knowledge.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"27 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2023-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10151536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asymptomatic 39 Weeks Abdominal Pregnancy - Video Report of a Case Occurred in Ivory Coast Resulting in a Live Birth.","authors":"Pietro Iovenitti,&nbsp;Valentina Galiano,&nbsp;Andrea Finco,&nbsp;Francesca Tiberio,&nbsp;Okon Gerard,&nbsp;Emanuele Garzia,&nbsp;Privat Guie","doi":"10.34763/jmotherandchild.20232701.d-23-00001","DOIUrl":"https://doi.org/10.34763/jmotherandchild.20232701.d-23-00001","url":null,"abstract":"<p><strong>Background: </strong>Despite the current advances in antenatal care and imaging methodologies in obstetrics, cases of advanced abdominal pregnancies are still reported, mostly in low- and middle-income countries where frequently only a few perinatal checks are performed and where these methodologies are sometimes not adopted in obstetrical outpatient settings.</p><p><strong>Case presentation: </strong>We report the video of a case of a 20-year-old I gravida Ivorian patient, sent to CHU de T reichville in Abidjan, Ivory Coast, for management of abdominal 39 weeks pregnancy after routine antenatal care. She was asymptomatic with a live foetus in transverse lie position. The anamnesis revealed four prenatal checks without ultrasound evaluation, the first one at 24 weeks of pregnancy. Emergency median longitudinal sub-umbilical laparotomy incision was performed. Foetal extraction was realized by transplacental incision due to omental placental implantation. A live female baby weighting 3350 grams was delivered, presenting bilateral clubfeet and an enlarged neck. The release of the adherent placenta required a partial omentectomy and left adnexectomy and was carefully removed following active bleeding from its detached margins. The newborn died of respiratory distress on the first day after birth. No autopsy was performed. Postoperative morbidity for the woman was minimal and she was discharged on the seventh post-operative day in good general condition.</p><p><strong>Conclusion: </strong>Abdominal pregnancies with a normal live foetus at such an advanced gestational age are extremely rare, and there are no available videos in the extant literature of the surgical procedure performed. Standardization of treatment principles, pre-operative preparation with imaging techniques (MRI, embolization of placental vessels) and adequately equipped and staffed neonatal units are necessary to optimize the foetus-maternal outcomes.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"27 1","pages":"30-32"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10298481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9755389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraperitoneally Retained Contraceptive Device After Uterine Perforation: A Case Report.","authors":"Hanan S Al-Khatlan,&nbsp;Aliaa M Al-Tuhoo,&nbsp;Mohannad Abu-Faza,&nbsp;Mariam Obaid,&nbsp;Ibrahim A Abdelazim,&nbsp;Ibrahim M Al-Kandari","doi":"10.34763/jmotherandchild.20232701.d-22-00054","DOIUrl":"https://doi.org/10.34763/jmotherandchild.20232701.d-22-00054","url":null,"abstract":"<p><p>A 29-year-old parous woman with a history of a T-shaped copper intrauterine device (IUD) insertion presented 8 months later with a complaint of the contraceptive device being missing. Computed tomography with contrast turned out to be superior to the combined abdominal and pelvic X-ray and transvaginal ultrasound in providing the detailed extrauterine location of the device between the urinary bladder and uterus. A laparoscopy was successful in the atraumatic freeing of the IUD from omental and bladder adhesions, and in its final removal.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"27 1","pages":"79-82"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9978458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal anomalies in gestational diabetes mellitus and risk of fetal anomalies in relation to pre-conceptional blood sugar and glycosylated hemoglobin.","authors":"Rami M M Al-Shwyiat, Ahmed M Radwan","doi":"10.34763/jmotherandchild.20222601.d-22-00040","DOIUrl":"10.34763/jmotherandchild.20222601.d-22-00040","url":null,"abstract":"<p><strong>Background: </strong>The risk of fetal anomalies (FAs) is increased in infants of diabetic mothers. FAs are closely related to the glycosylated hemoglobin (HbA1c) level in pregnancy.</p><p><strong>Objectives: </strong>To detect the prevalence of FAs in women with gestational diabetes mellitus (GDM).</p><p><strong>Material and methods: </strong>157 pregnant women with GDM were included in this study, and data from 151 women were analyzed. Beyond the regular antenatal check-up, the HbA1c was checked monthly during the antenatal follow-up. Collected data after delivery were analyzed to detect the prevalence of FAs in women with GDM and the risk of FAs in relation to the pre-conceptional blood sugar and HbA1c.</p><p><strong>Results: </strong>The FAs were recorded in 8.6% (13) of the 151 women with GDM. The recorded FAs were cardiovascular [2.6% (4)], musculoskeletal [1.3% (2)], urogenital [1.3% (2)], gastrointestinal [1.3% (2)], facial [0.7% (1)], central nervous system [0.7% (1)], and multiple FAs [0.7% (1)]. The uncontrolled pre-conceptional blood sugar significantly increased RR [RR 2.2 (95%CI: 1.7-2.9); P < 0.001], and odds of FAs [OR 17.05 (95%CI: 2.2-134.9); P = 0.007] in women with GDM. In addition, the HbA1c ≥6.5 significantly increased RR [RR 2.8 (95% CI: 2.1-3.8); P < 0.001], and odds of FAs [OR 24.8 (95% CI: 3.1-196.7); P = 0.002] in women with GDM.</p><p><strong>Conclusion: </strong>In this study, the prevalence of FAs in women with GDM was 8.6%. Uncontrolled pre-conceptional blood sugar and HbA1c ≥6.5 in the first trimester significantly increased the relative risk and the odds of FAs.</p>","PeriodicalId":73842,"journal":{"name":"Journal of mother and child","volume":"26 1","pages":"73-77"},"PeriodicalIF":0.0,"publicationDate":"2023-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9227062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}