Polymer Bulletin最新文献

{"title":"Evaluation of a green synthesized biopolymer polymethyl methacrylate grafted Moringa gum amphiphilic graft copolymer (MOG-g-PMMA) with polymeric-surfactant like properties for biopharmaceutical applications","authors":"Shreya Sharma,&nbsp;Trishna Bal","doi":"10.1007/s00289-024-05504-6","DOIUrl":"10.1007/s00289-024-05504-6","url":null,"abstract":"<div><p>The current study utilized a green synthesis where microwave-assisted free radical technique was applied for economical synthesis of a novel biocompatible polymethyl methacrylate grafted moringa gum amphiphilic graft copolymer, focusing on optimization based on percentage yield, percentage grafting, and intrinsic viscosity was performed, and analytical characterizations confirmed successful grafting. The copolymer demonstrated surfactant-like properties, as evidenced by the determined critical micelle concentration (CMC). Evaluation of its impact on poorly water-soluble drugs, simvastatin, and metronidazole benzoate, revealed efficient release within 60 min. Safety assessments, including <b>In vitro</b> assessments like hemocompatibility, bactericidal activity, fish toxicity, and <b>in vivo</b> evaluations such as oral toxicity, and wound repair studies and cell toxicity studies indicated the safety profile of prepared graft copolymer and explored its potential as a biopolymer for pharmaceutical delivery and tissue regrowth platform.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"17017 - 17047"},"PeriodicalIF":3.1,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142268815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis and optimization of bacterial cellulose production from food industry by-products by response surface methodolgy","authors":"Ashutosh Pandey,&nbsp;Annika Singh,&nbsp;Mukesh Kr. Singh","doi":"10.1007/s00289-024-05492-7","DOIUrl":"10.1007/s00289-024-05492-7","url":null,"abstract":"<div><p>The statistical optimization of process parameters using eco-friendly methods to utilize industrial waste for optimal bacterial cellulose (BC) production has yet to be explored. This study adopts a sustainable approach to optimize the biosynthesis of BC production parameters using response surface methodology. A Box-Behnken Experimental Design with three independent variables, such as incubation temperature, medium shaking frequency, and pH of the nitrogen source, was employed to prepare 17 samples of BC from traditional carbon sources (D-Glucose) and low-cost carbon sources such as molasses and beehive extract, which are byproducts of the food industry. The purity and presence of cellulose in the BC were characterized by chemical solubility tests and Fourier transform infrared spectroscopy analysis. The physical and crystalline morphology of the BC was characterized by scanning electron microscopy and X-ray diffractometry. The thermal stability and molar mass (m/z) of BC were analyzed using thermogravimetric analysis and MALDI-TOF mass spectrometry. The influence of process parameters on BC production yields was recorded as 6 g/L in glucose medium, 9.5 g/L in beehive extract medium, and 11.7 g/L in molasses medium under the optimized conditions of 29.08 °C incubation temperature, 126.98 rpm shaking frequency, and pH 5.68. The estimated total costs for BC production were $175/kg from the glucose-based medium, $85.08/kg from the molasses-based medium and $105.26/kg from the beehive extract-based medium. This study aimed to establish optimal conditions for producing comparatively cheap and cost-effective BC for biomedical applications.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"16965 - 16998"},"PeriodicalIF":3.1,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142253445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation and characterization of polyethylene glycol/sodium alginate aerogel beads loaded with biogenic zinc oxide nanoparticles: potential therapeutic option for treating multidrug-resistant bacteria and cytotoxic activity","authors":"Layth L. Hamid,&nbsp;Marwa El-Subeyhi,&nbsp;Hanan Hamed,&nbsp;Thamer Y. Mutter,&nbsp;Mohammed Hameed Sulaiman","doi":"10.1007/s00289-024-05505-5","DOIUrl":"10.1007/s00289-024-05505-5","url":null,"abstract":"<div><p>We present a novel 3D nanocomposite aerogel that combines the benefits of polyethylene glycol (PEG), sodium alginate (SA) and zinc oxide nanoparticles (ZnO NPs). PEG serves as the primary component of the aerogel, while SA acts as a filler to enhance its mechanical properties. Both PEG and SA contribute to the aerogel’s adsorption capabilities, while the incorporation of ZnO NPs enhances its antibacterial properties. The ZnO NPs were synthesized using a green method with the assistance of <i>Atriplex halimus</i> (<i>A. halimus</i>) extract. The biosynthesized ZnO NPs were added to a mixture of PEG and SA, and the resulting mixture was subjected to freeze-drying to obtain a porous aerogel beads with a distinctive 3D microstructure. The aerogel composite exhibited a highly porous and sheet-like surface as indicated by scanning electron microscope (SEM). Also, the physicochemical properties of the PEG/SA/ ZnO NPs aerogels composite were estimated such as crystallinity, chemical structure and optical properties. The PEG/SA/ZnO NPs aerogels beads exhibited a swelling rate exceeding 200%. The MIC of the ZnO NPs against <i>E. coli</i>, <i>A. baumannii</i>, <i>K. pneumonia</i>, <i>P. aeruginosa</i>, <i>S. aureus</i> and <i>S. epidermidis</i> were 12.5, 12.5, 25, 25, 6.25 and 6.25 U/ml, respectively. The aerogel demonstrated remarkable antibacterial activities, as evidenced by inhibition zones ranging between 15 and 22 mm² against multidrug-resistant bacteria (MDR). Moreover, the aerogels exhibited significant inhibition efficacy on the MDR bacterial growth with complete inhibition for all strains. These findings highlight the highly effective bactericidal properties of the aerogels. The cytotoxicity of both ZnO NPs and PEG/SA/ZnO NPs was evaluated using HeLa cell lines. The results showed that the ZnO NPs and PEG/SA/ZnO NPs exhibited reasonable anticancer activity against this cell line. The newly developed 3D composite PEG/SA/ZnO NPs aerogels exhibits broad-spectrum antibacterial capabilities against MDR bacterial strains for medical and pharmaceutical applications.</p></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"16999 - 17016"},"PeriodicalIF":3.1,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142253447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of silicious rock dust on mechanical, thermal and flammability behaviour of Himalayan nettle fibre-reinforced vinyl ester composite","authors":"A. Anbuchezian,&nbsp;S. Suresh Pungaiah,&nbsp;R. Muthukumaran,&nbsp;M. Nithya","doi":"10.1007/s00289-024-05489-2","DOIUrl":"10.1007/s00289-024-05489-2","url":null,"abstract":"<div><p>This research delves into the comprehensive assessment of a novel composite material, comprising Himalayan nettle fibre (HNF) and vinyl ester resin, reinforced with silicon-rich siliceous rock dust (SRD). The purpose of this study is to develop an eco-friendly composite material for various engineering applications. The HNF was used in chopped form, and the composites were prepared via hand layup process. Results of these composites revealed that the inclusion of SRD led to a significant enhancement in wear resistance with reduced sp. wear rate of 0.009 mm³/Nm and coefficient of friction of 0.22, indicating material’s resistance to wear. Similarly, flammability characteristics were rigorously examined through standard tests. The introduction of siliceous rock dust induced a substantial improvement in fire resistance, as evidenced in VN3 (HNF 40 vol.% and SRD 5 vol.%) composite by reduced flame propagation speed of 4.11 mm/min with HB and V-0 UL-94 ratings. Similarly, the composite’s thermal stability was increased with the incorporation of SRD. Composite VN3 (HNF 40 vol.% and SRD 5 vol.%) observed with high initial degradation temperature of 387 °C, respectively. The findings of this study are significant, showcasing the positive impact of silicon-rich siliceous rock dust on the dry sliding wear resistance, flammability and thermal stability of the composite. This innovative material has the potential to revolutionize industries where mechanical performance and fire resistance are of concern, including but not limited to construction, transportation, and aerospace.</p></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"16949 - 16964"},"PeriodicalIF":3.1,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142253448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of polyaniline particle size on the chromate adsorption from aqueous electrolyte","authors":"Nesrine Allal,&nbsp;Abderrezak Abdi,&nbsp;Radia Bagtache,&nbsp;Mohamed Trari","doi":"10.1007/s00289-024-05486-5","DOIUrl":"10.1007/s00289-024-05486-5","url":null,"abstract":"<div><p>In this contribution, we report the investigation on removing of the oxochromium (VI), a hazardous species, using HCl-doped polyaniline (PAni-HCl) as adsorbent versus particles size. PAni-HCl has been successfully elaborated by conventional oxidative chemical method in the temperature range (0–3 °C). The recovered powder was milled and sieved into size ranges of &lt; 50, 50–63, 125–160 and &gt; 200 µm. The batch adsorption experiments were performed at 25 °C, using 250 mg of PAni-HCl dispersed in 250 mL of Cr(VI) aqueous solution (250 mg L⁻¹). The Cr(VI) uptake was significantly influenced by both the particle size and contact time. Smaller particle sizes allow a quick initial adsorption and high removal efficiency (~100%). The kinetics of the Cr(VI) adsorption follow the pseudo-second-order model. A good correlation was demonstrated between the removal chromium (VI) properties (<i>Q</i>_e,exp, <i>k</i>₂ and <i>τ</i>(%)) and the (normalized) mean diameter ratio.</p></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"16935 - 16948"},"PeriodicalIF":3.1,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142253446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brief review of trans-ferulic acid-loaded polymeric nanoformulations: pharmacological applications and future perspectives","authors":"Usha Rani,&nbsp;Asha Rani,&nbsp;Rajesh Thakur","doi":"10.1007/s00289-024-05488-3","DOIUrl":"10.1007/s00289-024-05488-3","url":null,"abstract":"<div><p>Plants are mainly considered as the important source of energy and from ancient times plants, and the plants products are used in various form. These pharmacologically bioactive compounds have limited use due to their insolubility in water, and to overcome this, these compounds were encapsulated in biodegradable polymers and gums which enable them to be used practically for therapeutic purposes. In this review article we briefly discussed about the trans-ferulic acid-loaded polymeric nanoformulations which can be used for preclinical and clinical purpose. Trans-ferulic acid-loaded polymeric nanoformulations were synthesized using ionic gelation method. The polymeric nanoformulations have diameter mainly in nanometers which is mainly due to their high surface area to volume ratio. Their unique physical and chemical properties make them attractive for a variety of applications, such as drug administration, cosmetics, and environmental remediation. Plant science is becoming more and more interested in the topic of nanotechnology, particularly with regard to the use of nanomaterials as vehicles for agrochemicals or biomolecules and their enormous potential in different fields. It has been shown in recent years that significant advancements in nanotechnology have been made in the synthesis of nanoparticles and their use in diagnosis and treatment in medicine. More research is deemed necessary in this direction to optimize the synthesis and biofunctionalization of nanoparticles for different applications, as well as to better understand the mechanisms and enhance sustainability for human health. Lastly, we have examined a few cutting-edge and novel ferulic acid nanoformulations and we assume that this review article will provide researchers a chance to close the gaps in preclinical and clinical research.</p></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"16329 - 16354"},"PeriodicalIF":3.1,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142222292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lemongrass essential oil nanoemulsion formulations based on tragacanth gum and guar gum as durable anti-mosquito fabric finishing agents","authors":"Nurul Nabila Aini Abdullah,&nbsp;Azlan Kamari,&nbsp;Siew Tin Susana Wong,&nbsp;Norjan Yusof,&nbsp;Hidayatulfathi Othman,&nbsp;Mohd Zobir Hussein,&nbsp;Justin S. J. Hargreaves","doi":"10.1007/s00289-024-05490-9","DOIUrl":"10.1007/s00289-024-05490-9","url":null,"abstract":"<div><p>Mosquito-repellent textiles are classified as protective textiles designed to mitigate the presence of mosquito species recognised as vectors for diseases such as malaria and dengue fever. This study aimed to explore the feasibility of employing a nanoemulsion system containing lemongrass essential oil encapsulated with biopolymers, specifically tragacanth gum and cationic guar gum, as finishing materials on cotton and polyester fabrics. Being anionic biopolymer, tragacanth gum has resulted in outstanding zeta potential, polydispersity index, particle size and encapsulation efficiency with the values of − 38.1 mV, 0.2, 14.1 nm and 99%, respectively. The positively charged guar gum that interacted with aluminium chloride led to precipitation, which disfavoured retention and repellency properties. Based on correlation coefficient (<i>R</i>²) values for tragacanth gum (0.9832) and cationic guar gum (0.9761)-based nanoemulsions, the release of lemongrass essential oil from nanoemulsions followed the Korsmeyer–Peppas kinetic model. Following five cycles of washing and heating, the retention of tragacanth gum-based nanoemulsion on cotton and polyester was determined as 62% and 46%, respectively. From an Excito chamber study, 64% of <i>Aedes aegypti</i> were successfully repelled from nanoemulsion-treated cotton, whereas 53% of the same mosquito species were repelled from nanoemulsion-treated polyester. Overall, results from this study are in line with the mosquito vector control initiative outlined by the World Health Organization.</p></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"16903 - 16933"},"PeriodicalIF":3.1,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142222296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new porous composite hydroxyapatite/chitosan/microcrystalline-cellulose: synthesis, characterization and application to the adsorption of Eriochrome Black T","authors":"Yassine Benali,&nbsp;Nabil Mabrouki,&nbsp;Hassen Agougui,&nbsp;Mahjoub Jabli,&nbsp;Hatem Majdoub,&nbsp;Daniela Predoi,&nbsp;Steluța Ciobanu,&nbsp;Simona Liliana Iconaru,&nbsp;Ştefan Ţălu,&nbsp;Khaled Boughzala","doi":"10.1007/s00289-024-05496-3","DOIUrl":"10.1007/s00289-024-05496-3","url":null,"abstract":"<div><p>In the current study, a porous composite material, hydroxyapatite/chitosan/microcrystalline-cellulose (CaHAp–CS–MCC), was successfully prepared and used for the adsorption of Eriochrome Black T (EBT) from water. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), differential thermal analysis (DTA), thermogravimetric analysis (TGA), specific surface area (SSA), and atomic force microscope (AFM) were used to evaluate the physicochemical properties of the prepared adsorbents. CaHAp–CS–MCC exhibited a decrease in crystallinity and reduction in crystallite size. CaHAp–CS–MCC surface exhibited cracks and pores. AFM displayed changes in surface micro-texture of CaHAp, formation of new surface structures, and variations in particle size and distribution. Upon grafting CaHAp with CS and MCC, its specific surface area decreased from 139.224 to 11.775 m²/g. BET suggested that filling CaHAp pores by CS and MCC contributed to the reduction in surface area. The pore volume values decreased from 2.56 × 10^–1 (CaHAp) to 3.91 × 10^–2 cm³/g (CaHAp–CS–MCC). Adsorption equilibrium was reached at about 40 min. The adsorption capacities values of CaHAp–CS–MCC and CaHAp were equal to 248 mg/g and 92 mg/g, respectively. The pseudo-second order and the Langmuir equations fitted well the adsorption phenomenon. The calculated thermodynamic parameters showed an exothermic and non-spontaneous system.</p></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"16875 - 16902"},"PeriodicalIF":3.1,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142222298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In situ green synthesis of iron nanoparticles on PVA nanofiber and its application in adsorptive removal methylene blue","authors":"Mahdi Filsara,&nbsp;Zahra‑Beagom Mokhtari‑Hosseini,&nbsp;Masoumeh Mansoori-Rashvanloo","doi":"10.1007/s00289-024-05491-8","DOIUrl":"10.1007/s00289-024-05491-8","url":null,"abstract":"<div><p>This study presents a novel approach for environmentally friendly paint removal, focusing on the efficient removal of methylene blue from aqueous environments using iron nanoparticles embedded in polyvinyl alcohol nanofibers. Iron nanoparticles were synthesized via a green method employing green tea extract under optimized conditions and characterized by FESEM, DLS, TGA, DTG, EDS, FTIR, and XRD. The average size of synthesized iron nanoparticles was 22 nm. Two fabrication techniques were employed to embed the nanoparticles into polyvinyl alcohol nanofibers: electrospinning of a solution containing iron nanoparticles, and in situ synthesis of nanoparticles on the PVA nanofibers. Comparative analyses revealed superior methylene blue adsorption rates when nanoparticles were synthesized in situ on the nanofibers. Characterization techniques, including FESEM, XRD, and FTIR, confirmed the successful formation of nanoparticles on the nanofibers. Response surface method using central composite design (CCD) was performed to find the optimal removal conditions. Optimal removal (85%) occurred under adsorption conditions of pH 8.6, an initial methylene blue concentration of 30 mg/L, a nanofiber dose of 1.6 g/L, and a contact time of 100 min. Kinetic studies demonstrated a pseudo-second-order adsorption model, while Langmuir isotherm analysis indicated a maximum adsorption capacity of 24.509 mg/g. Thermodynamic analysis suggested the spontaneous and exothermic nature of the adsorption process. This composite membrane is an efficient and economical method for removal dye from wastewaters.</p></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"16827 - 16852"},"PeriodicalIF":3.1,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142222316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new drug delivery coated matrix membrane system for theophylline delivery","authors":"Gulsen Asman,&nbsp;Sevil Uyanik","doi":"10.1007/s00289-024-05473-w","DOIUrl":"10.1007/s00289-024-05473-w","url":null,"abstract":"<div><p>This study focuses on the evaluation and the drug release characteristics of a new coated matrix membrane (CMM) system, particularly emphasizing drug delivery from porous systems that offer more precise release control, especially for drugs with narrow therapeutic indexes (NTIs), such as theophylline. The parameters affecting the delivery of theophylline from the CMM were systematically studied. In the study, ethyl cellulose (ETC) served as the coating polymer, while poly (ethylene glycol) (PEG) was selected as the pore-forming agent. Poly (vinyl alcohol) (PVA) was used as the base polymer in the preparation of matrix membranes, and poly (vinyl pyrrolidone) (PVP) was preferred as the hydrophilicity balancing guest polymer. The effects of matrix membrane (MM) thickness, heat treatment temperature (HTT), coating layer thickness, drug loading concentration and coating layer porosity on the release rate of theophylline from CMM systems were all investigated. Additionally, the impacts of pH and temperature on theophylline release from CMM systems were examined. All experiments were conducted in vitro. By the study, 150 °C was determined as optimal HTT temperature. At more acidic pH values greater release rates were obtained. The release mechanism consistent with the Case I (Fickian) diffusion model and the activation energy for the permeation of theophylline through CMM systems was found as 62.355 J mol⁻¹. As a result of the study, it was determined that the optimized CMM system with improved release properties can control the released amount of theophylline and it was proposed as a promising material for the dermal delivery of theophylline in vivo.</p><h3>Graphical abstract</h3><p>A new drug delivery coated matrix membrane system for theophylline delivery.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":737,"journal":{"name":"Polymer Bulletin","volume":"81 18","pages":"16853 - 16874"},"PeriodicalIF":3.1,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142222297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}