Journal of frailty, sarcopenia and falls最新文献

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Evaluation of strategies to recruit and retain older people with dementia and their informal carers into a Tai Chi Trial to improve balance and prevent falls 评估招募和留住老年痴呆症患者及其非正式护理人员参加太极拳试验以改善平衡和预防跌倒的策略
Journal of frailty, sarcopenia and falls Pub Date : 2022-03-01 DOI: 10.22540/JFSF-07-001
M. Heward, Layla Johnson, S. Nyman
{"title":"Evaluation of strategies to recruit and retain older people with dementia and their informal carers into a Tai Chi Trial to improve balance and prevent falls","authors":"M. Heward, Layla Johnson, S. Nyman","doi":"10.22540/JFSF-07-001","DOIUrl":"https://doi.org/10.22540/JFSF-07-001","url":null,"abstract":"Abstract Objectives: Randomised control trials (trials) involving people with dementia lack detailed analysis of recruitment and retention strategies. To address this, we examined the effectiveness of strategies in “The TACIT Trial: TAi ChI for people with demenTia” Methods: We recruited dyads (people with dementia and carers) from 3 South of England sites utilising different strategies. Recruitment strategy effectiveness was measured by percent yield (number randomised of total referrals) and cost per randomised participant. Our retention strategy (maintaining contact with participants during weekly telephone calls) was measured by percent yield (number retained by six-month follow-up). Results: Of 359 dyads, 24% were randomised into the study (n=85). The most resource-intensive strategy (research nurses spending 30 minutes explaining the study) had the highest referral to randomisation rate. An incremental cost-effectiveness ratio suggested an alternative approach (nurses and doctors spending 5 minutes explaining the study) was most cost-effective. Retention rates were 86% (n=36/42; intervention group) and 81% (35/43; control group); main reasons for attrition were worsening health and lack of study interest. Conclusions: The results demonstrate person-centred strategies enabling staff to spend time with participants were effective in supporting recruitment and retention. Those designing future trials must consider such strategies and the associated costs.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 1","pages":"1 - 12"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43806385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computerized Tomography derived psoas muscle indices in a healthy young population in the United States 计算机断层扫描得出的腰肌指数在美国健康的年轻人群
Journal of frailty, sarcopenia and falls Pub Date : 2022-03-01 DOI: 10.22540/JFSF-07-038
Maxwell A. Lawlor, J. Oliveto, J. Geske, B. Khandalavala
{"title":"Computerized Tomography derived psoas muscle indices in a healthy young population in the United States","authors":"Maxwell A. Lawlor, J. Oliveto, J. Geske, B. Khandalavala","doi":"10.22540/JFSF-07-038","DOIUrl":"https://doi.org/10.22540/JFSF-07-038","url":null,"abstract":"Abstract Objective: Psoas muscle metrics from diagnostic computerized tomography (CT) scans are emerging as clinically relevant biomarkers. Most muscle metrics from the US population are from older cohorts with co-morbidities. Published reports from a young or healthy population in the United States on psoas muscle metrics optimized for age, body mass index (BMI), and sex are lacking. This study determines the psoas muscle index (PMI) and psoas muscle density (PMD) for a normal young Midwestern US population. Methods: Retrospective cross-sectional analysis of pre-existent abdominal non-contrast CT scans from a young (19-40 years old), Midwestern, predominately Caucasian population was conducted within Aquarius iNtuition software automatically after manual identification of the psoas muscle. Electronic medical records provided access to subject data and archived CT scans were reviewed. Results: From 193 (45 male, 148 female) CT scans, for males, PMI was 5.9 cm2/m2 (SD=1.7) and PMD 48.4 HU (SD=5.5); for females PMI was 5.4 cm2/m2 (SD=1.4) and PMD 48.18 HU (SD=5.5). BMI was significantly correlated with PMI and PMD for both men (p<0.001, p<0.001 respectively) and women (p<0.001, p<0.001 respectively). Conclusion: Psoas muscle metrics are newly generated for PMI and PMD in a healthy population, allowing for future comparison studies determining muscle status.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 1","pages":"38 - 46"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43862543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
B12 levels and frailty syndrome B12水平和虚弱综合症
Journal of frailty, sarcopenia and falls Pub Date : 2022-03-01 DOI: 10.22540/JFSF-07-032
Elisavet E Pyrgioti, Nikolaos D. Karakousis
{"title":"B12 levels and frailty syndrome","authors":"Elisavet E Pyrgioti, Nikolaos D. Karakousis","doi":"10.22540/JFSF-07-032","DOIUrl":"https://doi.org/10.22540/JFSF-07-032","url":null,"abstract":"Abstract Vitamin B12, widely known as cobalamin, is a water-soluble vitamin crucial for human metabolism. It is synthesized only by prokaryotic organisms and since humans do not have the ability to synthesize it, they rely on its exogenous dietary intake. After its consumption, vitamin B12 undergoes a complicated procedure of absorption and assimilation and it is essential for cellular function, especially for nervous system, red blood cell production and DNA synthesis. Deficiency of vitamin B12 is considered as an important public health issue worldwide, while it is common in the elderly. Deficiency of this vitamin, as well as high levels, indicate a risk factor for morbidity with various clinical manifestations. Frailty is an age-related syndrome, which affects the elderly and is characterized by decreased function in many physiological systems, accompanied by vulnerability to stressors. A narrative non-systematic mini review of the literature was conducted and highlighted that vitamin B12 levels may have an impact on frailty and vice versa. As shown in several studies, vitamin B12 levels may be related to sarcopenia, cognitive and musculoskeletal disorders, neurological or psychiatric symptoms, which are closely linked to frailty. Furthermore, it is suggested that the extensions of frailty may affect the bioavailability of vitamin B12.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 1","pages":"32 - 37"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48942360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Otago Exercise Program Delivery using Digital Practice: A Prospective Case Report 使用数字实践的奥塔哥运动项目交付:前瞻性案例报告
Journal of frailty, sarcopenia and falls Pub Date : 2022-03-01 DOI: 10.22540/jfsf-07-047
Cheryl J. Hardy-Gostin, Kelly J. Negley, Jade J. Bender-Burnett
{"title":"Otago Exercise Program Delivery using Digital Practice: A Prospective Case Report","authors":"Cheryl J. Hardy-Gostin, Kelly J. Negley, Jade J. Bender-Burnett","doi":"10.22540/jfsf-07-047","DOIUrl":"https://doi.org/10.22540/jfsf-07-047","url":null,"abstract":"Abstract Activity restrictions during the COVID-19 pandemic left many older adults without access to community-based falls prevention programs. Despite a lack of evidence to support the digital delivery of exercise and rehabilitation, these services were quickly implemented during the pandemic in an effort to prevent the transmission of COVID-19, yet support a continuity of care. Our report describes the novel practice and digital delivery of a condensed Otago Exercise Program, a well-documented falls prevention program, to an 83-year-old female with high falls risk. After four weeks of the Otago Exercise Program via digital delivery, the patient in our case had notable improvement in her scores on the Timed Up and Go, Five Times Sit to Stand, 30-Second Chair Stand Test and One Leg Stance tests. Our findings necessitate the additional exploration of the digital delivery of exercise for future community-based falls prevention programs and provide an alternate method of delivery for falls prevention for practitioners to consider.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 1","pages":"47 - 51"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49039006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Achieving the hip fracture Best Practise Tariff during the COVID-19 pandemic. 在新冠肺炎大流行期间实现髋部骨折最佳实践关税
Journal of frailty, sarcopenia and falls Pub Date : 2022-03-01 DOI: 10.22540/JFSF-07-013
Mohammed Ali, Ahmed Fadulelmola, Marie Urwin, Cristian Nita
{"title":"Achieving the hip fracture Best Practise Tariff during the COVID-19 pandemic.","authors":"Mohammed Ali, Ahmed Fadulelmola, Marie Urwin, Cristian Nita","doi":"10.22540/JFSF-07-013","DOIUrl":"10.22540/JFSF-07-013","url":null,"abstract":"<p><strong>Objectives: </strong>Achieving the hip fracture best practice tariff is associated with decreased mortality rates. The aim of this study is to evaluate the impact of Covid-19 pandemic on achieving Best Practice Tariff.</p><p><strong>Methods: </strong>We retrospectively reviewed all adult hip fractures admitted to our unit between March and June 2020. Patient's characteristics, place of residence, delirium assessment, and mobility status were recorded. All the Best practice Tariff criteria have been analysed. Covid-19 was diagnosed using reverse transcriptase polymerase chain reaction.</p><p><strong>Results: </strong>178 patients with a mean age of 82.8 years presented with hip fractures during the study period. 18 patients (10.1%) tested positive for COVID-19. 44.4% failed to achieve the BPT from the COVID-19 positive group and 22.5% from the negative group.</p><p><strong>Conclusion: </strong>Based on this study, hip fractures associated with Covid-19 infection are more likely to fail the BPT and have higher 30-day mortality rates compare to the COVID-19 negative patients.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 1","pages":"13-17"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8886778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42420864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteosarcopenia School. 骨质疏松症学校。
Journal of frailty, sarcopenia and falls Pub Date : 2021-12-01 DOI: 10.22540/JFSF-06-231
Yannis Dionyssiotis, Konstantinos Prokopidis, Panagiotis Vorniotakis, Eleftherios Bakas
{"title":"Osteosarcopenia School.","authors":"Yannis Dionyssiotis, Konstantinos Prokopidis, Panagiotis Vorniotakis, Eleftherios Bakas","doi":"10.22540/JFSF-06-231","DOIUrl":"10.22540/JFSF-06-231","url":null,"abstract":"<p><p>Osteosarcopenia has been proposed as a syndrome in a subset of frail individuals at higher risk of falls, fractures and institutionalization. In this paper, we will go over the translational aspects of sarcopenia and osteoporosis research and highlight outcomes from different interventions. In addition, preventative measures and therapeutic interventions that can benefit both muscle and bone simultaneously will be analysed also. A new holistic concept called Osteosarcopenia School will be presented. This new concept is based on counselling and education of patients as part of a rehabilitation program, aiming to reduce the risk of social isolation, falls and fractures, and subsequent disability through muscle strengthening and balance training. In this patient group, the combination of pharmaceutical treatments and specific exercise programmes are essential to counteract the consequences of osteosarcopenia. Finally, educational programmes targeting patient functionality through social reintegration may have a substantial impact on their daily living activities and overall quality of life.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"6 4","pages":"231-240"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5b/9b/JFSF-6-231.PMC8649862.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39621053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A mixed-methods feasibility study of a sit-to-stand based exercise programme to maintain knee-extension muscle strength for older patients during hospitalisation. 一项基于坐立运动方案的混合方法可行性研究,以维持住院期间老年患者的膝关节伸展肌肉力量。
Journal of frailty, sarcopenia and falls Pub Date : 2021-12-01 DOI: 10.22540/JFSF-06-189
Peter Hartley, Roman Romero-Ortuno, Christi Deaton
{"title":"A mixed-methods feasibility study of a sit-to-stand based exercise programme to maintain knee-extension muscle strength for older patients during hospitalisation.","authors":"Peter Hartley,&nbsp;Roman Romero-Ortuno,&nbsp;Christi Deaton","doi":"10.22540/JFSF-06-189","DOIUrl":"https://doi.org/10.22540/JFSF-06-189","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the acceptability of an exercise programme and to identify barriers and facilitators to compliance with the programme from the participants' perspective.</p><p><strong>Methods: </strong>Patients aged 75 years or older were recruited within the first 36 hours of hospital admission. Participants were randomised to complete two strengthening-based (intervention arm) or stretching-based (control arm) exercise sessions per-day. At hospital discharge, participants were asked to take part in interviews with a member of the research team exploring the barriers and facilitators to adherence to the intervention.</p><p><strong>Results: </strong>15 participants (7 intervention arm, 8 control arm) were recruited before the trial was stopped due to COVID-19. Both groups showed reductions in knee-extension strength, and improvements in functional mobility at discharge from hospital. A total of 23/60 intervention sessions were classed as 'complete', 12/60 as partially complete, and 25/60 were missed entirely. Eight participants took part in interviews. Intrinsic factors that impacted participation in the research, related to current health, health beliefs, and experience of multi-morbidity or functional decline. Staff had both a positive and negative effect on participant adherence to the intervention.</p><p><strong>Conclusions: </strong>The exercise intervention was well received, with most participants describing health benefits, though intervention fidelity was lower than expected.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"6 4","pages":"189-203"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/89/JFSF-6-189.PMC8649864.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39761098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of probable sarcopenia in community-dwelling older Greek people. 希腊社区居住老年人可能的肌肉减少症患病率。
Journal of frailty, sarcopenia and falls Pub Date : 2021-12-01 DOI: 10.22540/JFSF-06-204
Maria Tsekoura, Evdokia Billis, Charalampos Matzaroglou, Elias Tsepis, John Gliatis
{"title":"Prevalence of probable sarcopenia in community-dwelling older Greek people.","authors":"Maria Tsekoura,&nbsp;Evdokia Billis,&nbsp;Charalampos Matzaroglou,&nbsp;Elias Tsepis,&nbsp;John Gliatis","doi":"10.22540/JFSF-06-204","DOIUrl":"https://doi.org/10.22540/JFSF-06-204","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of this study was to assess the prevalence rate of probable sarcopenia and to determine the factors associated with it in older people living in Western Greece.</p><p><strong>Methods: </strong>Probable sarcopenia was estimated based on cut-off values for handgrip strength (HGS) as recommended by EWGSOP2. Information about socio-demographic, chronic diseases, fear of falls and lifestyle of the participants were also collected. HGS was assessed using a SAEHAN dynamometer. Calf circumference was assessed with inelastic tape. A logistic regression analysis was performed in order to determine associated risk factors.</p><p><strong>Results: </strong>The sample comprised 402 participants (292 women;110 men), with a mean age of 71.51±7.63 years. Overall, 25.4% of the elderly participants were diagnosed with probable sarcopenia (men:36.4%; women:21.2%). The findings of this study demonstrated that probable sarcopenia was positively associated with age (OR=0.14, 95% CI=0.008 to 0.200), gender (OR=-0.6, 95% CI=-0.700 to -0.530), Body mass Index (OR=0.01, 95% CI=-0.030 to -0.005), Skeletal muscle mass index (OR=0.05, 95% CI=0.030 to 0.080), calf circumference (OR=0.02, 95% CI=0.007 to 0.040), and comorbidities (OR=0.04, 95% CI=0.030 to 0.080).</p><p><strong>Conclusion: </strong>There was a 25.4% prevalence of probable sarcopenia in Greek elderly. The results highlight the importance of the detection of HGS and probable sarcopenia in older people in order to develop effective strategies of prevention and intervention of sarcopenia.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"6 4","pages":"204-208"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ad/7f/JFSF-6-204.PMC8649860.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39761099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Frailty associations with socioeconomic status, healthcare utilisation and quality of life among older women residing in regional Australia. 居住在澳大利亚地区的老年妇女的衰弱与社会经济地位、保健利用和生活质量的关系。
Journal of frailty, sarcopenia and falls Pub Date : 2021-12-01 DOI: 10.22540/JFSF-06-209
Shi-Jynn Yong, Stella M Gwini, Monica C Tembo, Boon L Ng, Chong Han Low, Robert G Malon, Trisha L Dunning, Julie A Pasco, Mark A Kotowicz
{"title":"Frailty associations with socioeconomic status, healthcare utilisation and quality of life among older women residing in regional Australia.","authors":"Shi-Jynn Yong,&nbsp;Stella M Gwini,&nbsp;Monica C Tembo,&nbsp;Boon L Ng,&nbsp;Chong Han Low,&nbsp;Robert G Malon,&nbsp;Trisha L Dunning,&nbsp;Julie A Pasco,&nbsp;Mark A Kotowicz","doi":"10.22540/JFSF-06-209","DOIUrl":"https://doi.org/10.22540/JFSF-06-209","url":null,"abstract":"<p><strong>Objectives: </strong>The health and well-being of older women may be influenced by frailty and low socioeconomic status (SES). This study examined the association between frailty and SES, healthcare utilisation and quality of life (QOL) among older women in regional Australia.</p><p><strong>Methods: </strong>Cross-sectional analysis of the Geelong Osteoporosis Study was conducted on 360 women (ages ≥60yr) in the 15-year follow up. Frailty was identified using modified Fried's phenotype. Individual SES measures and healthcare utilisation were documented by questionnaire. Area-based SES was determined by cross-referencing residential addresses with the Australian Bureau of Statistics Index of Relative Socio-economic Advantage and Disadvantage (IRSAD). QOL was measured using the Australian World Health Organisation Quality of Life Instrument (WHOQoL-Bref). Multinomial logistic regression was conducted with frailty groupings as outcome.</p><p><strong>Results: </strong>Sixty-two (17.2%) participants were frail, 199 (55.3%) pre-frail and 99 (27.5%) robust. Frail participants were older with higher body mass index. Frailty was associated with lower education but not marital status, occupation or IRSAD. Strong associations with frailty were demonstrated for all WHOQoL-Bref domains. Frailty was associated with more primary care doctor visits (p<0.001).</p><p><strong>Conclusions: </strong>This population-based study highlights the significant impact of frailty on older women, indicating reduced QOL and increased primary care doctor visits.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"6 4","pages":"209-217"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9a/7f/JFSF-6-209.PMC8649863.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39621051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Hyponatremia in the frail. 体弱者低钠血症。
Journal of frailty, sarcopenia and falls Pub Date : 2021-12-01 DOI: 10.22540/JFSF-06-241
Nikolaos D Karakousis, Nikolaos A Kostakopoulos
{"title":"Hyponatremia in the frail.","authors":"Nikolaos D Karakousis,&nbsp;Nikolaos A Kostakopoulos","doi":"10.22540/JFSF-06-241","DOIUrl":"https://doi.org/10.22540/JFSF-06-241","url":null,"abstract":"<p><p>As the lifespan increases, special attention has been given to the supportive care needs of the elderly. Frailty is an important issue in third age, since it is related to poor quality of life and mortality. The prevalence of pathological conditions related to sodium levels, specifically hyponatremia, is also present in the elderly. Yet, it is unclear, if hyponatremia and frailty are related to each other. This review summarizes the current state of knowledge regarding hyponatremia and frailty and analyzes five independent studies which searched for an association between those two parameters. As indicated by this study results, hyponatremia consists a risk factor for frailty. This could be explained by an effect of hyponatremia on sarcopenia and on cognitive function, which consist components of frailty. Thus, it is essential to monitor sodium levels in the elderly and to develop related interventions (e.g. using arginine vasopressin antagonists) in order to prevent frailty.</p>","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"6 4","pages":"241-245"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/ee/JFSF-6-241.PMC8649861.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39621054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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