Journal of frailty, sarcopenia and falls最新文献_第9页

Comparison of Habitual and Maximal Gait Speed and their Impact on Sarcopenia Quantification in German Nursing Home Residents. 德国养老院居民习惯性和最大步态速度的比较及其对肌肉减少症量化的影响。

Journal of frailty, sarcopenia and falls Pub Date : 2022-12-01 DOI: 10.22540/JFSF-07-199

Daniel Haigis, Silas Wagner, Gorden Sudeck, Annika Frahsa, Ansgar Thiel, Gerhard W Eschweiler, Andreas M Niess

{"title":"Comparison of Habitual and Maximal Gait Speed and their Impact on Sarcopenia Quantification in German Nursing Home Residents.","authors":"Daniel Haigis, Silas Wagner, Gorden Sudeck, Annika Frahsa, Ansgar Thiel, Gerhard W Eschweiler, Andreas M Niess","doi":"10.22540/JFSF-07-199","DOIUrl":"https://doi.org/10.22540/JFSF-07-199","url":null,"abstract":"Objectives: Sarcopenia is characterized by loss of muscle strength and muscle mass. The EWGSOP2 specifications include physical functioning determination for quantification of the sarcopenia severity. However, there is a lack in the use of habitual and maximal gait speed and their influence on sarcopenia quantification. We hypothesize differences in sarcopenia quantification using habitual and maximal gait speed.Methods: Sixty-six residents from five nursing homes were examined. Habitual and maximal gait speed were measured by 4-meter-walking-Test. McNemar-Test and χ2-test were used to identify quantification differences. Effect sizes of both gait speeds were calculated with Spearman's rank-correlation-coefficient.Results: Significant difference was identified for twenty-two residents in physical functioning classification by McNemar-Test (p<.001). χ2-Test identified a significant frequency distribution for sarcopenia categories between both gait speeds (χ2 (df2)=11.215, p=.004; Cramer's V=.412). Significant correlations (p<.05) were only shown for maximal gait speed in variables falls in the last three months (|rs|=.326), Barthel-Index (|rs|=.415), and SARC-F (|rs|=.335).Conclusions: The use of habitual and maximal gait speed has a significant impact on sarcopenia quantification in nursing home residents. An adapted standardization in the EWGSOP2 specifications should follow.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 4","pages":"199-206"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/da/b0/JFSF-7-199.PMC9729759.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10404940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to: Sarcopenia in Hemiplegia. 偏瘫患者肌肉减少症的更正。

Journal of frailty, sarcopenia and falls Pub Date : 2022-12-01 DOI: 10.22540/JFSF-07-257

Maria C Papadatou

引用次数: 0

Association of Obesity with Cognitive Impairment and Depression among Oldest Old Population having Frailty syndrome. 患有虚弱综合征的高龄老人中肥胖与认知障碍和抑郁的关系。

Journal of frailty, sarcopenia and falls Pub Date : 2022-12-01 DOI: 10.22540/JFSF-07-207

Gunampalli Anaika, Sai Sruthi Regalla, Bana Manishaa Reddy, Enakshi Ganguly, Pawan Kumar Sharma

{"title":"Association of Obesity with Cognitive Impairment and Depression among Oldest Old Population having Frailty syndrome.","authors":"Gunampalli Anaika, Sai Sruthi Regalla, Bana Manishaa Reddy, Enakshi Ganguly, Pawan Kumar Sharma","doi":"10.22540/JFSF-07-207","DOIUrl":"10.22540/JFSF-07-207","url":null,"abstract":"Objectives: The objectives were to estimate prevalence of obesity among frail individuals aged ≥80 years and examine the association of obesity with cognitive impairment and depression among frail individuals aged ≥80 years.Methods: Two-hundred community-dwelling participants aged ≥80 years, were enrolled; 166 frail participants were further analyzed. Obesity and adiposity were determined by Body Mass Index (BMI), Waist Circumference (WC) and Body Fat Percentage (BF%). Cognitive impairment and Depression were assessed using Mini Mental State Examination (MMSE) and Geriatric Depression Scale (GDS-15). Frailty was assessed by Fried criteria. Chi-Square, t-test, trend-analysis and Logistic Regression (LR) were done.Results: Obesity among Frail individuals aged ≥80 years was 40% using BMI and 73.2% using WC. Obesity was inversely associated with cognitive impairment and depression among frail individuals. Severity of cognitive impairment and depression was lower among obese frail than non-obese frail. Trend-analysis showed decreasing cognitive impairment and depression with increasing BF%. On LR, obesity among frail individuals had inverse association with cognitive impairment and depression.Conclusion: Obesity among frail individuals aged ≥80 years was associated with lower odds of cognitive impairment and depression in our population. Positive effects of weight gain in oldest old frail individuals and development of cognitive impairment and dementia should be explored in further researches.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 4","pages":"207-221"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/19/c8/JFSF-7-207.PMC9729753.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10399013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is handgrip strength a useful tool to detect slow walking speed in older Indian adults: A cross-sectional study among geriatric outpatients in a tertiary care hospital in South India. 握力是检测印度老年人步行慢速的有用工具吗:一项对印度南部一家三级医院老年门诊患者的横断面研究

Journal of frailty, sarcopenia and falls Pub Date : 2022-12-01 DOI: 10.22540/JFSF-07-183

Reuben Jerrald Felix, Rakesh Mishra, Jini Chirackel Thomas, Benny Paul Wilson, Antonisamy Belavendra, Gopinath Kango Gopal

{"title":"Is handgrip strength a useful tool to detect slow walking speed in older Indian adults: A cross-sectional study among geriatric outpatients in a tertiary care hospital in South India.","authors":"Reuben Jerrald Felix, Rakesh Mishra, Jini Chirackel Thomas, Benny Paul Wilson, Antonisamy Belavendra, Gopinath Kango Gopal","doi":"10.22540/JFSF-07-183","DOIUrl":"https://doi.org/10.22540/JFSF-07-183","url":null,"abstract":"Objectives: To determine whether handgrip strength can be used as a proxy for detecting slow walking speed in older adults. Measuring walking speed in older adults can be challenging as cognitive and functional decline may have a significant impact on test performance.Methods: Hundred subjects aged >/= 60 were recruited. Slow walking speed was defined as walking speed <1.0 m/s. Handgrip strength was measured using handheld dynamometer. Multiple linear regression analysis was used to determine the relationship between the two.Results: The mean age of the study participants was 67.8±6.2 years. There were 63 males and 37 females. The mean handgrip strength of the participants was 23±5.9 kgs. Older subjects had slow gait speed (r=-0.40, p<0.001) while patients with higher BMI (r=0.36, p<0.001), handgrip strength (r=0.72, p<0.001) and appendicular lean mass (r=0.53, p<0.001) had normal gait speed. On multiple linear regression analysis, only handgrip strength (OR 0.71; 95% CI 0.58-0.87, p=0.001) and nutritional status (OR 8.60; 95% CI 1.98 - 37.40, p=0.004) were found to have a significant association with walking speed.Conclusions: Our study shows that handgrip strength assessment can be used as a surrogate indicator for detecting slow walking speed. Large population studies are warranted to examine its validity.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 4","pages":"183-191"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ad/6e/JFSF-7-183.PMC9729754.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10404942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of weight-bearing exercise on the mechanisms of bone health in young females: A systematic review. 负重运动对年轻女性骨骼健康机制的影响：系统综述。

Journal of frailty, sarcopenia and falls Pub Date : 2022-12-01 DOI: 10.22540/JFSF-07-231

Tommy J Cartledge, Joey Murphy, Charlie E Foster, Byron Tibbitts

{"title":"The effect of weight-bearing exercise on the mechanisms of bone health in young females: A systematic review.","authors":"Tommy J Cartledge, Joey Murphy, Charlie E Foster, Byron Tibbitts","doi":"10.22540/JFSF-07-231","DOIUrl":"10.22540/JFSF-07-231","url":null,"abstract":"Weight-bearing exercise (WBE) has been identified as an appropriate approach for increasing peak bone mass, however, there is a lack of specific physical activity recommendations in this area. Thus, the aim of this systematic review is to determine the optimal mode of WBE, specifically identifying the intensity, duration, frequency, and load, to elicit the optimal effect on bone mass in young females, aged 5-18. A literature search was conducted from the 28th of June to the 20th of July 2021 using PubMed/Medline, Web of Science and SPORTDiscus. The search produced 1405 results, of which 15 were deemed appropriate for inclusion. The majority of studies (n=12) found a significant positive effect for at least one bone measure through their respective WBE exposure (p<0.05). Bone mass accrual was found to be site-specific depending on WBE exposure type, load, and maturity status. Also, longitudinal effects on bone mass accrual were found exclusively in gymnastics participants, even if participation level decreased (i.e., retirement). The results of this study support the use of WBE to improve parameters of bone health. However, further research is needed as the optimal mode of WBE to elicit the optimal effect on bone mass is still unclear.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 4","pages":"231-250"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/10/43/JFSF-7-231.PMC9729757.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10399019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of multimodal circuit exercises for chronic musculoskeletal pain in older adults: A randomized controlled trial protocol. 多模态回路运动对老年人慢性肌肉骨骼疼痛的有效性:一项随机对照试验方案。

Journal of frailty, sarcopenia and falls Pub Date : 2022-09-01 DOI: 10.22540/JFSF-07-175

Daniele B G Ribeiro, Paulo R V Gentil, Renan A Resende, Rodrigo L Carregaro, Sérgio T D Fonseca, Wagner R Martins

{"title":"Effectiveness of multimodal circuit exercises for chronic musculoskeletal pain in older adults: A randomized controlled trial protocol.","authors":"Daniele B G Ribeiro, Paulo R V Gentil, Renan A Resende, Rodrigo L Carregaro, Sérgio T D Fonseca, Wagner R Martins","doi":"10.22540/JFSF-07-175","DOIUrl":"https://doi.org/10.22540/JFSF-07-175","url":null,"abstract":"Studies have shown that musculoskeletal pain is one of the most prevalent health conditions that affects many individuals worldwide. In older adults, persistent pain is a widely prevalent and a disabling condition of multiple contributing factors: physical, mental, and social. Consequently, their quality of life is hampered. We aimed to analyze the effectiveness of a multimodal circuit exercise program on chronic musculoskeletal pain and disabling in older adults. This is a randomized parallel study (two arms) with blinded outcome assessments. The participants' recruitment will be done by a non-probabilistic sampling resulting from invitations to Basic Health Units (BHU). The sample size estimation indicated 164 participants. Participants will be allocated, by means of a randomization process, to one of two groups (82 for each group): Experimental Group (multimodal circuit exercise) or Control Group (cycle of multidisciplinary lectures on pain and stretching exercise). All analyses will be processed using the RStudio software, with significance when a p-value of 2 tails is less than 5% (p<0.05). Statistical analysis will follow the intention to treat. Trial registration: ClinicalTrials.gov NCT04719130, January 20, 2021.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":" ","pages":"175-182"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/43/JFSF-7-175.PMC9433943.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40365449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparison of CT-body composition measurements in non-cancer and cancer patients from a single UK centre. 来自英国单一中心的非癌症和癌症患者的ct身体成分测量的比较。

Journal of frailty, sarcopenia and falls Pub Date : 2022-09-01 DOI: 10.22540/JFSF-07-117

Josh McGovern, Ross D Dolan, Donogh Maguire, Paul G Horgan, Barry J Laird, Donald C McMillan

{"title":"A comparison of CT-body composition measurements in non-cancer and cancer patients from a single UK centre.","authors":"Josh McGovern, Ross D Dolan, Donogh Maguire, Paul G Horgan, Barry J Laird, Donald C McMillan","doi":"10.22540/JFSF-07-117","DOIUrl":"https://doi.org/10.22540/JFSF-07-117","url":null,"abstract":"Objectives: Establish the prevalence of low skeletal muscle index and density in our population, by comparing age and sex matched cohorts of patients with and without cancer, using standardized methodology for CT-Body composition (CT-BC).Methods: A retrospective analysis of prospectively collected data. Patients admitted to our institution between 17th March 2020 - 1st May 2020, with confirmed coronavirus disease and imaging suitable for CT-BC (n=52), were age and sex matched with patients undergoing resection for colorectal cancer (n=52).Results: 104 patients were included in the final analysis. 43% (n=45) were male, 77% (n=80) were aged 65 years or older, 50% (n=50) were overweight (BMI ≥25) and 53% (n=55) were systemically inflamed (mGPS ≥1). The prevalence of a low SMI (56% vs. 65%) and low SMD (83% vs. 67%) was similar between cohorts. A low SMI and SMD were both associated with age (p<0.05 and p<0.01, respectively) on univariate analysis. On multivariate analysis, a low SMD was independently associated with age (OR 2.38 (1.34-4.22), p=0.003) and mGPS (OR 2.10 (1.20-3.68), p=0.01).Conclusions: In conclusion, the prevalence of a low SMI and low SMD was similar in non-cancer and cancer cohorts in our institution.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":" ","pages":"117-122"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/30/JFSF-7-117.PMC9433946.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40365448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Induced frailty and acute sarcopenia are overlapping consequences of hospitalisation in older adults. 诱发性虚弱和急性肌肉减少症是老年人住院治疗的重叠后果。

Journal of frailty, sarcopenia and falls Pub Date : 2022-09-01 DOI: 10.22540/JFSF-07-103

Carly Welch, Carolyn Greig, Zeinab Majid, Tahir Masud, Hannah Moorey, Thomas Pinkney, Thomas Jackson

{"title":"Induced frailty and acute sarcopenia are overlapping consequences of hospitalisation in older adults.","authors":"Carly Welch, Carolyn Greig, Zeinab Majid, Tahir Masud, Hannah Moorey, Thomas Pinkney, Thomas Jackson","doi":"10.22540/JFSF-07-103","DOIUrl":"10.22540/JFSF-07-103","url":null,"abstract":"Objectives: To determine the effects of hospitalisation upon frailty and sarcopenia.Methods: Prospective cohort study at single UK hospital including adults ≥70 years-old admitted for elective colorectal surgery, emergency abdominal surgery, or acute infections. Serial assessments for frailty (Fried, Frailty Index, Clinical Frailty Scale [CFS]), and sarcopenia (handgrip strength, ultrasound quadriceps and/or bioelectrical impedance analysis, and gait speed and/or Short Physical Performance Battery) were conducted at baseline, 7 days post-admission/post-operatively, and 13 weeks post-admission/post-operatively.Results: Eighty participants were included (mean age 79.2, 38.8% females). Frailty prevalence by all criteria at baseline was higher among medical compared to surgical participants. Median and estimated marginal CFS values and Fried frailty prevalence increased after 7 days, with rates returning towards baseline at 13 weeks. Sarcopenia incidence amongst those who did not have sarcopenia at baseline was 20.0%. However, some participants demonstrated improvements in sarcopenia status, and overall sarcopenia prevalence did not change. There was significant overlap between diagnoses with 37.3% meeting criteria for all four diagnoses at 7 days.Conclusions: Induced frailty and acute sarcopenia are overlapping conditions affecting older adults during hospitalisation. Rates of frailty returned towards baseline at 13 weeks, suggesting that induced frailty is reversible.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"7 3","pages":"103-116"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/56/25/JFSF-7-103.PMC9433945.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9505138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and validation of a fall risk Questionnaire in Greek community-dwelling individuals over 60 years old. 希腊60岁以上社区居民跌倒风险问卷的开发和验证。

Journal of frailty, sarcopenia and falls Pub Date : 2022-09-01 DOI: 10.22540/JFSF-07-133

Chrysoula Argyrou, Yannis Dionyssiotis, Antonios Galanos, Ingka Kantaidou, John Vlamis, Ioannis K Triantafyllopoulos, George P Lyritis, Ismene A Dontas, Efstathios Chronopoulos

{"title":"Development and validation of a fall risk Questionnaire in Greek community-dwelling individuals over 60 years old.","authors":"Chrysoula Argyrou, Yannis Dionyssiotis, Antonios Galanos, Ingka Kantaidou, John Vlamis, Ioannis K Triantafyllopoulos, George P Lyritis, Ismene A Dontas, Efstathios Chronopoulos","doi":"10.22540/JFSF-07-133","DOIUrl":"https://doi.org/10.22540/JFSF-07-133","url":null,"abstract":"Objectives: The purpose of this study was to develop a questionnaire that can reliably recognize Greek individuals over the age of 60 with increased risk of falls.Methods: An 11-item self-reported Questionnaire (LRMS) was developed and delivered to 200 individuals. Collected data were compared to Timed Up and Go (TUG), Falls Efficacy Scale-International (FES-I), Tinetti Assessment Tool, Geriatric Depression Scale-15 (GDS-15) and Morse fall scale. The results were statistically analyzed.Results: Correlation between LRMS and the examined tools was high TUG (r=0.831), FES-I (r=-0.820), Tinetti balance (r=-0.812), Tinetti gait (r=-0.789), GDS-15 (r=-0.562), and Morse fall scale (r=0.795). Cronbach's alpha for LRMS total score was 0.807. ICC of the LRMS total score was 0.991. The area under the curve of LRMS was 0.930 (cut-off point 10.5, 95% C.I. 0.88 - 0.98, p<0.001, sensitivity=86%, specificity=98%) with TUG as gold standard, 0.919 (cut-off point 11.5, 95% C.I. 0.88 - 0.96, p<0.001, sensitivity=85%, specificity=89%) with FES-I and 0.947 (cut-off point 10.5, 95% C.I. 0.91 - 0.98, p<0.001, sensitivity=93%, specificity=91%) with Tinetti.Conclusions: The LRMS Questionnaire showed sufficient internal consistency, excellent test-retest reliability and high correlation with the already established tools for fall risk assessment. It is short and easy to use without assistance from specially trained personnel.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":" ","pages":"133-146"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1d/20/JFSF-7-133.PMC9433940.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40365450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Outcomes of radical cystectomy in pT4 bladder cancer frail patients: Α high-volume single center study. pT4膀胱癌虚弱患者根治性膀胱切除术的结果:Α大容量单中心研究。

Journal of frailty, sarcopenia and falls Pub Date : 2022-09-01 DOI: 10.22540/JFSF-07-147

Panagiotis Velissarios Stamatakos, Dimitrios Moschotzopoulos, Ioannis Glykas, Charalampos Fragkoulis, Nikolaos Kostakopoulos, Georgios Papadopoulos, Georgios Stathouros, Odysseas Aristas, Athanasios Dellis, Athanasios Papatsoris, Konstantinos Ntoumas

{"title":"Outcomes of radical cystectomy in pT4 bladder cancer frail patients: Α high-volume single center study.","authors":"Panagiotis Velissarios Stamatakos, Dimitrios Moschotzopoulos, Ioannis Glykas, Charalampos Fragkoulis, Nikolaos Kostakopoulos, Georgios Papadopoulos, Georgios Stathouros, Odysseas Aristas, Athanasios Dellis, Athanasios Papatsoris, Konstantinos Ntoumas","doi":"10.22540/JFSF-07-147","DOIUrl":"https://doi.org/10.22540/JFSF-07-147","url":null,"abstract":"Objectives: This study aims to evaluate the effect of frailty in patients undergoing radical cystectomy (RC) for locally advanced bladder cancer.Methods: In this retrospective, single center study we evaluated 51 patients with pT4 bladder cancer treated with radical cystectomy between 2016-2020. Patient frailty was assessed with the Clinical Frailty Scale (CFS). Furthermore, six separate parameters (early mortality index within 30 days after surgery, death after one year, length of stay, respiratory complications, readmission index, total hospital charges) were also evaluated. The patients were categorized on three groups (Group 1, 2, 3) based on the CFS.Results: A total of 51 pT4 RC patients were included in the study. Mean age was 75.6 years. Early mortality rate at 30 days after surgery was low all the groups. One year mortality rate was higher in Group 2 (22%) and 3 (69%). The length of stay and the number of patients with respiratory complications were also higher in the frailer groups. 30 days readmission rate was 22% in Group 2 and 38% in Group 3.Conclusions: Preoperative frailty is associated with worse postoperative results after RC. CFS is an objective tool for patient risk stratification and can predict postoperative complications and mortality.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":" ","pages":"147-150"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/e3/JFSF-7-147.PMC9433942.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40365451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1