Journal of frailty, sarcopenia and falls最新文献_第3页

Drugs with Anticholinergic Properties and Association with Hip Fractures in Older Patients: A Danish Nationwide Cohort-Study. 具有抗胆碱能特性的药物与老年患者髋部骨折的关系：丹麦全国队列研究

Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-207

Rebekka Vedelsbøl, Pavithra Laxsen Anru, Jesper Ryg

{"title":"Drugs with Anticholinergic Properties and Association with Hip Fractures in Older Patients: A Danish Nationwide Cohort-Study.","authors":"Rebekka Vedelsbøl, Pavithra Laxsen Anru, Jesper Ryg","doi":"10.22540/JFSF-09-207","DOIUrl":"10.22540/JFSF-09-207","url":null,"abstract":"Objectives: Hip fractures (HFx) resulting from falls are a significant health concern, and drugs with anticholinergic properties (DAP) increase the risk of falls. This study aimed to assess the association between use of DAP at hospital admission and HFx risk in older patients.Methods: This nationwide population-based study included all patients ≥65 years admitted to Danish geriatric wards during 2005-2014. Outcome of interest was first HFx within 2-years follow-up. The Anticholinergic Cognitive Burden (ACB) scale quantified DAP use. Cox regression analysis of data from four national registries was adjusted for activities of daily living, age, marital status, admission year, BMI, fracture history, previous admissions, dementia, anti-osteoporotic drugs, and Charlson comorbidity index.Results: 74,589 patients (62.8% female) were included, 45,463 (60.9%) received DAP at index, and 7,861 HFx occurred during follow-up. Cumulative 2-year HFx hazard was highest for ACB=0 (15.3%). Higher ACB-score was not associated with increased HFx risk in univariable nor multivariable analyses. In sensitivity analysis, use of DAP with high anticholinergic burden (≥2) did not alter results.Conclusions: In this high-incidence national cohort, higher ACB-score was not associated with increased HFx risk. Our results call for further research on association between specific DAP and risk of HFx.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"207-217"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142128163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the Cycle of Physical Frailty in Falls Clinic Attendees Through Structural Equation Modeling. 通过结构方程模型研究跌倒门诊就诊者身体虚弱的周期。

Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-227

Román Romero Ortuño, Eoin Duggan

{"title":"Examining the Cycle of Physical Frailty in Falls Clinic Attendees Through Structural Equation Modeling.","authors":"Román Romero Ortuño, Eoin Duggan","doi":"10.22540/JFSF-09-227","DOIUrl":"10.22540/JFSF-09-227","url":null,"abstract":"In 1998, Fried and Walston introduced the Cycle of Frailty (CF) as a foundational concept for defining the physical frailty phenotype (FP). While the FP has been extensively validated, the CF hypothesis lacks equivalent support. This study aimed to internally validate the CF using structural equation modeling (SEM) in a clinical dataset of adults aged 50 or older attending an outpatient falls clinic. Measures included: age, morbidity, nutrition, sarcopenia by bioelectrical impedance, VO2max, handgrip strength, basal metabolic rate (BMR), 5-times chair stand test (5CST), physical activity, and total energy expenditure (TEE). The SEM, incorporating CF hypothesized causal pathways, was tested using IBM® SPSS® Amos 27.0.0 (maximum likelihood method) with a sample of 102 adults (mean age 69.8 years, 58.8% women). Overall, the SEM was supported by the data (χ2 = 44.4, df = 37, p = 0.189), with significant (p < 0.05) regression weights for morbidity→sarcopenia, age→sarcopenia, sarcopenia→VO2max, sarcopenia→handgrip strength, handgrip strength→5CST, physical activity→TEE, TEE→nutrition, and BMR→TEE. However, nutrition→sarcopenia, sarcopenia→BMR, VO2max→5CST, and 5CST→physical activity were not significant. Although the SEM was limited by inclusion of surrogate CF measures (e.g., 5CST instead of gait speed, VO2max based on age-predicted maximal/resting heart rate), it provided some internal support for the CF hypothesis.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"227-231"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Benchmarking Exercise Programme for Older People (BEPOP): Design, Results and Recommendations from The First Wave of Data Collection. 老年人基准测试计划（BEPOP）：第一波数据收集的设计、结果和建议。

Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-169

Lorna Caulfield, Susanne Arnold, Sarah De Biase, Charlotte Buckland, Philip Heslop, Christopher Hurst, Avan A Sayer, Dawn A Skelton, Miles D Witham

{"title":"The Benchmarking Exercise Programme for Older People (BEPOP): Design, Results and Recommendations from The First Wave of Data Collection.","authors":"Lorna Caulfield, Susanne Arnold, Sarah De Biase, Charlotte Buckland, Philip Heslop, Christopher Hurst, Avan A Sayer, Dawn A Skelton, Miles D Witham","doi":"10.22540/JFSF-09-169","DOIUrl":"10.22540/JFSF-09-169","url":null,"abstract":"Objectives: The Benchmarking Exercise Programme for Older People (BEPOP) service improvement project seeks to determine and promote the exercise training characteristics associated with positive outcomes for resistance exercise for older people living with, or at risk of, sarcopenia or physical frailty.Methods: Mixed-methods service improvement project. Ten UK National Health Service physiotherapist-led therapy services delivering exercise interventions for older people submitted anonymized data for up to 20 consecutive patients. A multidisciplinary expert panel generated a report and recommendations with site-specific benchmarking data and feedback. In parallel, participating physiotherapy team members were interviewed to elicit feedback on BEPOP rationale, processes and perceived value.Results: Data from 188 patients were included, mean age 80 years (range 60-101). 115 (61%) received objective assessment of strength-based physical performance. Bodyweight exercises (173 [92%]) and resistance bands (49 [26%]) were the commonest exercise modalities. Exercises progressed predominantly through increased repetitions (163 [87%]) rather than increased load. 50 (30%) had no reassessment of outcomes; only 68 (41%) were signposted to follow-on exercise services. Staff interviews identified themes around knowledge, diagnosis, data collection and practice reflection.Conclusion: BEPOP was feasible to deliver and generated actionable insights for service improvement via improved diagnosis, measurement and progression of resistance exercise.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"169-183"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of an Oral Nutritional Supplementation and Physical Exercise Intervention on Older Adults at Risk for Sarcopenia. 口服营养补充剂和体育锻炼干预对易患肌肉疏松症的老年人的影响

Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-184

Thiago J M Gonçalves, Bruna T Carlos, Mayara S de Souza, Valeria C Jorge, Sandra E A B Gonçalves, Rafaela A Campos, Valeria A S Rosenfeld

{"title":"Effects of an Oral Nutritional Supplementation and Physical Exercise Intervention on Older Adults at Risk for Sarcopenia.","authors":"Thiago J M Gonçalves, Bruna T Carlos, Mayara S de Souza, Valeria C Jorge, Sandra E A B Gonçalves, Rafaela A Campos, Valeria A S Rosenfeld","doi":"10.22540/JFSF-09-184","DOIUrl":"10.22540/JFSF-09-184","url":null,"abstract":"Objectives: Sarcopenia is a skeletal muscle mass (SMM) disease characterized by loss of strength with generalized loss of SMM. The aim of this study is to evaluate the effects of a 12-week intervention on SMM, strength, and functionally in older adults.Methods: This is a retrospective analysis of an intervention protocol with older adults at risk of sarcopenia who performed a daily intake of oral nutritional supplements (ONS) and resistance training exercise (RET), 3 times a week. Calf circumference (CC), bioelectrical impedance analysis (BIA), handgrip strength (HGS) and Timed Up and Go (TUG) were performed at baseline and at 12 weeks.Results: Fifty-one older adults were included. The mean age was 76.3 ± 8.3 years and 68.6% were women. After 12 weeks, the study showed an increase of CC in cm (1.9 ± 2.5, p < 0.001), increase of strength in kg (5.4 ± 2.1, p < 0.001), reduction of TUG in seconds (-2.4 ± 4.8, p = 0.001), increase of free-fat mass in kg (1.0 ± 1.3, p < 0.001) and SMM in kg (0.9 ± 0.5, p < 0.001).Conclusions: Nutritional intervention with ONS associated with RET, can increase muscle strength, SMM and functionality among older adults at risk for sarcopenia.","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"184-191"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Economic Cost Analysis of Implementing a Frailty Care Bundle to Reduce Risk of Hospital Associated Decline Among Older Patients. 实施虚弱护理捆绑方案以降低老年患者住院相关衰退风险的经济成本分析》（An Economic Cost Analysis of Implementing a Frailty Care Bundle to Reduce Risk of Hospital Associated Decline Among Older Patients）。

Journal of frailty, sarcopenia and falls Pub Date : 2024-09-01 DOI: 10.22540/JFSF-09-218

Aileen Murphy, Federica de Blasio, Ann Kirby, Marguerite de Foubert, Corina Naughton

{"title":"An Economic Cost Analysis of Implementing a Frailty Care Bundle to Reduce Risk of Hospital Associated Decline Among Older Patients.","authors":"Aileen Murphy, Federica de Blasio, Ann Kirby, Marguerite de Foubert, Corina Naughton","doi":"10.22540/JFSF-09-218","DOIUrl":"10.22540/JFSF-09-218","url":null,"abstract":"Objective: To conduct an economic cost analysis and budget impact assessment (BIA) of implementing the Frailty Care Bundle (FCB) intervention nationally over five-years for hip fracture patients. The FCB was designed to reduce hospital associated decline in older hospitalised patients.Methods: The FCB was delivered in two Irish hospitals on two wards per hospital. A micro level cost analysis, from the Irish health service perspective was undertaken. Direct costs of the FCB were considered (personnel, training, resources), expressed in Euros (2020). For the BIA national population estimates for hip fracture and costs avoided were based on 18% difference in patients returning to their baseline capability in the post compared to pre-intervention group, valued using cost estimates of functional decline.Results: We estimated total intervention costs at €53,619 (89% for personnel) and the average cost per patient was €156.03. The expected costs of implementing the FCB nationally over 12-months was €57,274 per hospital (€72.92 per patient). The BIA for an expected targeted population (16,000 over 5 years), estimated that the cost of implementing the FCB (€1.2m) was less than the expected value of functional decline avoided owing to the intervention (€3.6m), suggesting a positive net effect (€2.4m).Conclusion: Investment in the FCB can be offset with more rapid patient return to baseline functional capability, reducing health care costs. Trial and Protocol Registration (retrospective): BMC ISRCTN 15145850, (https://doi.org/10.1186/ISRCTN15145850).","PeriodicalId":73754,"journal":{"name":"Journal of frailty, sarcopenia and falls","volume":"9 3","pages":"218-226"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors Associated with Subjective Aging Among Older Outpatients In Northern - India 印度北部老年门诊患者主观衰老的相关因素

Journal of frailty, sarcopenia and falls Pub Date : 2024-06-01 DOI: 10.22540/jfsf-09-122

Urza Bhattarai, Arun Gautam, Manisha Shrestha, Anusha Rayamajhi, Rohan Basnet, Manicka Saravanan, A. B. Dey, Prasun Chatterjee

引用次数: 0

A Case Report of Probable Secondary Sarcopenia After Intensive Care Hospitalization 重症监护住院后可能出现继发性肌少症的病例报告

Journal of frailty, sarcopenia and falls Pub Date : 2024-06-01 DOI: 10.22540/jfsf-09-157

Cihat Kurt, Yasemin Yumusakhuylu, Belgin Erhan

引用次数: 0

Commentary on: Are multimorbidity patterns associated with fear of falling in community-dwelling older adults? 评论：多病模式与居住在社区的老年人害怕跌倒有关吗？

Journal of frailty, sarcopenia and falls Pub Date : 2024-06-01 DOI: 10.22540/jfsf-09-161

Lloyd D. Hughes

引用次数: 0

Understanding the delivery of the Falls Management Exercise Programme (FaME) across the U.K. 了解英国各地实施跌倒管理练习计划 (FaME) 的情况。

Journal of frailty, sarcopenia and falls Pub Date : 2024-06-01 DOI: 10.22540/jfsf-09-096

Helen Hawley-Hague, Jodi Ventre, Chloe Quigley, D. Skelton, Chris Todd

引用次数: 0

The Feasibilty of the Motor Control Home Ergonomics Elderlies' Prevention of Falls (McHeELP) Programme in Patients with Sarcopenia: A Pilot Study 运动控制家庭工效学老年人预防跌倒 (McHeELP) 计划在肌肉疏松症患者中的可行性：试点研究

Journal of frailty, sarcopenia and falls Pub Date : 2024-06-01 DOI: 10.22540/jfsf-09-089

M. Tsekoura, C. Matzaroglou, Sofia Xergia, Yannis Dionyssiotis, E. Tsepis, Vassiliki Sakellari, Evdokia Billis

引用次数: 0