Advances in Polymer Technology最新文献

{"title":"A Review on Vehicle Tire Elastomers and Tire Wear Particles: Composition, Degradation Mechanisms, Analytical Methods, and Predictive Multiscale Computational Modeling","authors":"Roman Tangalychev,&nbsp;Vasilii Korotenko,&nbsp;Valentin Ivanov","doi":"10.1155/adv/1352384","DOIUrl":"https://doi.org/10.1155/adv/1352384","url":null,"abstract":"<p>The study of the properties, chemical composition, and degradation patterns of rubber materials used in vehicle tires remains a complex and interdisciplinary task. Rubber for tires—more precisely, complex mixtures of elastomers containing fillers, plasticizers, binders, and other additives—is a condensed chemically active material, the composition and microstructure of which crucially determine the performance characteristics of tires, their durability, and the formation of tire wear particles (TWPs). These particles contribute to environmental pollution and therefore require a detailed understanding of their formation mechanisms, chemical structure, and identification methods. This review provides a comprehensive description of current knowledge about the chemical nature of elastomeric tire systems and the effects of external and operational factors on aging and structural degradation, as well as key physicochemical parameters that determine both performance and environmental impact. We briefly describe the chemical reactions that occur during operation, including oxidation, crosslinking, chain breaking, and the processes of filler–polymer interaction (vulcanization and silica embedding), as well as their role in mechanical stress and long-term stability of the material. In addition, the article discusses modern analytical approaches to the collection, identification, and quantification of TWP, including laboratory methods for determining morphological, chemical, and molecular characteristics. The central part of this review is devoted to multiscale chemical computer modeling as a tool for predicting the behavior and properties of materials, as well as ways of their decomposition and further behavior in nature. We summarize the research results using methods of quantum mechanics (QMs), polyatomic molecular dynamics (MDs), and coarse-grained (CG) modeling, highlighting how these approaches provide a concrete understanding of key structural and property relationships in elastomeric mixtures. Promising areas of future research include combining QM–MD–CG workflows with experimental verification and developing standardized predictive models linking rubber composition to mechanical moduli and environmental emissions.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/1352384","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Basic Characterization of an Industrial Elastomeric O-Ring for Petrochemical Sealing Using Accessible Laboratory Techniques","authors":"Soheila Lashgari,&nbsp;Seyed Omidreza Mousavi,&nbsp;Azam Ghadami,&nbsp;Daryoush Haghi,&nbsp;Somayeh Lashgari,&nbsp;Sakineh Hajebi","doi":"10.1155/adv/8270302","DOIUrl":"https://doi.org/10.1155/adv/8270302","url":null,"abstract":"<p>Rubber O-rings are vital sealing components in petrochemical and refinery applications, where reliable performance under harsh conditions is essential. This study employs a multianalytical approach to investigate the material composition, curing system, and performance of an industrial O-ring. Fourier transform infrared (FTIR) spectroscopy identified characteristic bands at 1394 cm⁻¹, confirming the O-ring as a fluorocarbon elastomer (FKM), with a peak at 3428 cm⁻¹ (attributed to N–H groups) diminishing post-Soxhlet extraction, indicating an amine-based curing system. Thermogravimetric analysis (TGA) revealed a 91.69% weight loss up to 700°C, with significant degradation at 493°C (58.37% loss between 400 and 550°C) and a residual mass of 8.31%, suggesting minimal filler content. Mechanical testing demonstrated a modulus of 4.60 MPa, tensile strength of 5.86 MPa, strain at break of 165%, and a compression set of 41%, reflecting robust material properties. The O-ring was identified as Viton A (a vinylidene fluoride [VDF]/hexafluoropropylene [HFP] copolymer) with a diamine curing system, typical of early FKM grades used in demanding chemical environments. While FTIR identifies key functional groups, its integration with TGA (for thermal stability and filler content), Soxhlet extraction (for additive isolation), and mechanical testing provides a practical, accessible framework for reverse engineering industrial elastomers—offering actionable insights into material suitability for petrochemical sealing applications.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/8270302","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148324007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-Cation Fe/Zn Complexes and Their Catalysis Effects on Polyurethane Synthesis","authors":"Lei Yang,&nbsp;Minghao Sun,&nbsp;Xiaoyu Dong,&nbsp;Chenxi Wang,&nbsp;Jinghua Du,&nbsp;Xiaohua Hou,&nbsp;Sheng Cheng,&nbsp;Chao Liu,&nbsp;Haoyan Yin,&nbsp;Yunsheng Ding","doi":"10.1155/adv/9666254","DOIUrl":"https://doi.org/10.1155/adv/9666254","url":null,"abstract":"<p>Replacing toxic organotin catalysts in polyurethane (PU) synthesis remains a critical challenge, as current alternatives suffer from either low activity or diminished product performance. Herein, we report a new class of dual-cation Fe/Zn complexes through strategic integration of imidazolium frameworks with transition metal centers, characterized by FT-IR, nuclear magnetic resonance (NMR) spectroscopy, and single crystal X-ray diffraction (SC-XRD). These catalysts exhibit activities higher than commercial organotin and tertiary amines while maintaining excellent biocompatibility as well. Mechanistic investigations establish a 7.4-fold enhancement in conversion rates through synergistic cooperation, as imidazolium cations and Zn²⁺ centers both activate isocyanate groups, while coulombic repulsion between cationic moieties effectively prevents metal aggregation. This work provides both a sustainable alternative to tin catalysts for PU synthesis and a general design principle for multifunctional polymerization catalysis strategies.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/9666254","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148281945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Croton Macrostachyus Leaf Extract Loaded Nanofibers for Potential Wound Dressings","authors":"Biruk Fentahun Adamu,&nbsp;Jing Gao,&nbsp;Abdul Khalique Jhatial,&nbsp;Hermela Ejegu,&nbsp;Shaojie Tan,&nbsp;Kura Alemayehu Beyene,&nbsp;Erkihun Zelalem Liyew,&nbsp;Feteya Hayredin Endress,&nbsp;Demesew Ephrem Getahun","doi":"10.1155/adv/9112136","DOIUrl":"https://doi.org/10.1155/adv/9112136","url":null,"abstract":"<p><i>Croton macrostachyus</i> (CM) is rich in bioactive compounds, including carbohydrates, saccharides, phenolic acids, and diterpenes, known for their antibacterial, wound-healing, and anti-inflammatory properties. This study aims to leverage these properties by incorporating CM leaf extract into polycaprolactone–cellulose acetate (PCL–CA) nanofibers to develop advanced wound dressings that prevent infection and promote healing. For the first time, CM leaf extract was successfully integrated into PCL–CA nanofibers via electrospinning. The resulting composite nanofibers were subjected to a comprehensive analysis of their morphology, porosity, crystallinity, thermal stability, hydrophilicity, and mechanical strength. In vitro evaluations assessed antibacterial efficacy, wound healing, cytotoxicity, and drug release profiles. The results demonstrated that PCL–CA–CM nanofibers form interconnected, bead-free structures with fiber diameters of 326 ± 85 nm to 374 ± 92 nm and a porosity of 61–80%. The mats exhibited significant antibacterial activity, reducing <i>Staphylococcus aureus</i> (<i>S. aureus</i>) by 66.77–99% and <i>Escherichia coli</i> (<i>E. coli</i>) by 58.18–99%. Cytotoxicity assays confirmed minimal toxicity with cell viability exceeding 70%. Furthermore, nanofibers significantly enhanced cell migration. The incorporation of CM also improved hydrophilicity, swelling capacity, and mechanical strength of the mats. These findings collectively highlight the potential of CM-loaded PCL–CA nanofibers as an effective advanced wound care application.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/9112136","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148237674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Polymer Based Materials for Substituting Single Use Plastics Within the Circular Economy Framework","authors":"Usman Saleem,&nbsp;Vladimír Kočí","doi":"10.1155/adv/5382267","DOIUrl":"https://doi.org/10.1155/adv/5382267","url":null,"abstract":"<p>The need to find sustainable substitutes for conventional plastics made from petroleum has been heightened by the global problem of plastic pollution and the depletion of fossils. Natural polymer-based bioplastics are among the most promising answers because they can lessen dependency on fossil fuels while providing cleaner and greener end-of-life (EOL) alternatives. This study provides a thorough and critical examination of the formation, functionality, and alignment of circularity of natural polymers, including cellulose, starch, chitosan, lignin, alginate, and gelatin. It also evaluates popular bioplastics, such as polylactic acid (PLA), polybutylene adipate terephthalate (PBAT), and polyhydroxyalkanoates (PHAs), pointing out their advantages and disadvantages in different industrial domains. In order to improve material functioning, the paper also examines novel blending processes, bio-based plasticizers, and new monomers. Life cycle assessment (LCA), circular design concepts, and the real-world difficulties of manufacturing scalability are given particular attention. Through creative diagrams, comparison tables, and a radar chart showing EOL paths, this paper presents a unique integrated viewpoint on the role of natural polymers in the shift to a circular bioeconomy. A critical evaluation of present policy frameworks and tactical suggestions to get beyond obstacles to broad adoption are included in the study’s conclusion. Computational material science-assisted advances in polymer chemistry and applications pave the way for a complete approach to these problems by designing for biodegradability and recyclability. This review examines the ways in which advancements in science, new legal frameworks, societal norms, and economic constraints pave the way for the shift to a circular economy of polymers.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/5382267","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148237673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Effects of Maleic Anhydride and Epoxidized Palm Oil on PLA/Tapioca Starch Biocomposites","authors":"Gautheman Kurup,&nbsp;Muhammad Fadzlee Firas Bin Mohd Fadzillah,&nbsp;Nishata Royan Rajendran Royan,&nbsp;Nabilah Afiqah Mohd Radzuan,&nbsp;Abu Bakar Sulong,&nbsp;Farrahshaida Mohd Salleh","doi":"10.1155/adv/3535137","DOIUrl":"https://doi.org/10.1155/adv/3535137","url":null,"abstract":"<p>The proliferation of single-use plastics (SUPs) has raised concerns about waste management and environmental sustainability. Polylactic acid (PLA) can be used as a green alternative, but its high cost and brittleness have hindered its widespread adoption. This paper explores the use of compatibilizer and plasticizer to enhance the compatibility and flexibility of PLA/tapioca starch (TS) biocomposites. Maleic anhydride (MA) was grafted to form PLA-g-MA and used as a compatibilizer followed by the addition of epoxidized palm oil (EPO) as a plasticizer. Results demonstrated an overall positive impact, indicating the opportunity to develop an optimized blend composition. Fourier transform infrared (FTIR) confirmed the presence of new functional groups, while thermal analysis indicated successful compatibilization. Plasticization was verified by a reduced <i>T</i>_<i>g</i>. Rheology confirmed pseudoplastic behavior with <i>n</i> value of 0.510 &lt; <i>n</i> &lt; 0.552 and activation energy (<i>E</i>_<i>a</i>) of 25.25 kJ/mol. Tensile tests showed that the addition of 5% PLA-g-MA improved the tensile strength by 13%, while the addition of 2% of EPO doubled the elongation at break. The Young’s modulus of the plasticized blend observed a decrease, which indicated improved ductility. Morphology confirmed compatibilization and demonstrated microfibrils. Overall, the PLA/tapioca biocomposite exhibited favorable properties, high quality, and cost-effectiveness, indicating good potential in short-term food packaging applications.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/3535137","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148174293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioinspired Electrospun Chitosan–Based Materials for Tissue Regeneration","authors":"Teboho Clement Mokhena,&nbsp;Asanda Mtibe,&nbsp;Lerato Hlekelele,&nbsp;Amos Nhlapo,&nbsp;Katekani Shingange,&nbsp;Sivuyisiwe Mapukata,&nbsp;Antonio Benjamim Mapossa,&nbsp;Mokgaotsa Jonas Mochane,&nbsp;Eric Mathete,&nbsp;Ndivhuwo Shumbula,&nbsp;Odireleng Martin Ntwaeaborwa","doi":"10.1155/adv/8830315","DOIUrl":"https://doi.org/10.1155/adv/8830315","url":null,"abstract":"<p>Chitosan (CS) is a cationic biopolymer that has shown unique opportunities in tissue engineering. The well-defined geometry, porosity, easy processability, and antimicrobial and antifungal properties are particularly beneficial for tissue regeneration. This review outlines the progress made in the preparation of bioinspired electrospun CS for tissue regeneration. The article concentrates on bioinspired electrospun CS and CS-based composites which have appeared in a good number of publications in the literature and enriched the field of tissue engineering. It also highlights the upscaling of electrospun nanofibers with recent advanced technologies. Finally, the overall summary, challenges, and future perspective in tissue regeneration based on bioinspired CS and related composite materials is presented.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/8830315","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148174294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polymers and Bioactive Molecules: Wound Dressings Fighting Against Resistant Bacterial Infections","authors":"Carla Andrea Nomura-Contreras,&nbsp;Alejandra Romero-Montero,&nbsp;Isidro Badillo Ramírez,&nbsp;Emilio Franco-Valdés,&nbsp;Nayeli Rodríguez-Fuentes,&nbsp;Gerardo Leyva-Gómez,&nbsp;María Luisa Del Prado-Audelo","doi":"10.1155/adv/1632605","DOIUrl":"https://doi.org/10.1155/adv/1632605","url":null,"abstract":"<p>Disruptions in the skin restoration process can impair wound healing and lead to severe clinical complications, particularly in environments prone to microbial colonization and biofilm formation. Modern wound dressings are, therefore, designed not only to restore tissue integrity but also to actively modulate the wound microenvironment and mitigate infections caused by multidrug-resistant microorganisms. In this context, polymeric matrices play a fundamental role by providing structural support, moisture regulation, and controlled delivery capabilities that guide cellular responses and tissue regeneration. Recent advances have focused on integrating naturally derived bioactive agents, such as stem cell-derived components, vitamins, growth factors, and phytochemicals, into polymer-based systems to enhance their therapeutic performance due to their effectiveness depending strongly on the protective and regulatory functions of the polymeric carrier. Polymeric platforms enable stabilization, sustained release, and targeted activity of these molecules, thereby improving their bioavailability and functional impact within the wound site. This review examines the wound healing process from a polymer engineering perspective and discusses emerging strategies for incorporating natural and bioactive molecules into polymeric wound dressings to address the dual challenge of tissue regeneration and antimicrobial resistance (AMR). Emphasis is placed on how polymer properties govern therapeutic outcomes. Finally, we outline current advantages, limitations, and future directions in the design of advanced polymer-based wound dressings capable of enhancing healing while combating resistant microbial infections.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/1632605","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148174089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A High-Stability Hydrogel Sensor for Pulse Monitoring","authors":"Jinli Zhou,&nbsp;Chenxiao Wang,&nbsp;SaiYa Wang,&nbsp;Erwei Yuan,&nbsp;Fan Xiong,&nbsp;TianXiao Pan,&nbsp;Shulei Guo,&nbsp;Huizeng Xia,&nbsp;Gaoqiang Feng,&nbsp;Hongying Yang","doi":"10.1155/adv/7999020","DOIUrl":"https://doi.org/10.1155/adv/7999020","url":null,"abstract":"<p>Recent advances in flexible sensor technology have driven the widespread adoption of smart wearable devices. Pulse sensors, which monitor heartbeats, provide essential information about human health and serve as vital tools in personal health management, disease prevention, and medical diagnosis. However, developing sensor materials with high reproducibility for the precise detection of weak pulse signals remains challenging. In this work, a pulse-sensing composite conductive hydrogel (PCP) was fabricated via a five-cycle freeze–thaw method for application in traditional Chinese medicine (TCM) pulse diagnosis. The hydrogel was composed of polyvinyl alcohol (PVA), chitosan quaternary ammonium salt (CHACC), and PEDOT:PSS in an optimized mass ratio of PVA:CHACC = 7:3. It exhibits outstanding tensile strain (567%), a broad sensing range (0%–250%), fast response (0.7 s), excellent repeatability (over 1000 cycles), and high conductivity (1.5 S/m). These properties allow precise monitoring of motion signals from different body regions with sustained stability. Furthermore, the hydrogel showed antibacterial activity against <i>Staphylococcus aureus</i> with an inhibition zone diameter of 18.2 ± 0.5 mm, indicating enhanced biosafety. An integrated three-channel wristband sensor based on this hydrogel was also developed, enabling real-time and accurate detection of human pulse signals. This system provides a promising platform for digitized pulse diagnosis in wearable health monitoring.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/7999020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148174087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in Polyhydroxybutyrate-Based Scaffolds for Tissue Engineering Through Pre and Postprocessing Modifications","authors":"Reyhan Gholami,&nbsp;Mohammad Mohammadalipour,&nbsp;Hesamodin Astaraki","doi":"10.1155/adv/3728039","DOIUrl":"https://doi.org/10.1155/adv/3728039","url":null,"abstract":"<p>Electrospinning (ES) techniques produce fibrous scaffolds that closely mimic the three-dimensional architecture of the extracellular matrix (ECM), providing a favorable microenvironment for cell proliferation, migration, differentiation, and function within a supportive framework. Replicating this native structure with nontoxic materials is essential for tissue regeneration (RG). Polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrate (PHB), are a class of natural polymers that have been extensively studied for applications in tissue engineering (TE). The inherent biocompatibility, biodegradability, piezoelectric properties (PEs), and mechanical strength of this biological macromolecule make it an attractive candidate for scaffold fabrication, as its degradation by-products exhibit very low cytotoxicity. Despite these advantages, PHB exhibits intrinsic limitations such as hydrophobicity, slow degradation rate, and brittleness, which restrict its broader applicability. To overcome these challenges, various modification strategies, including blending, nanocomposite (NC) incorporation, and surface modification, have been developed to enhance its physicochemical and biological performance. This review comprehensively presents recent advancements in the design and fabrication of PHB-based electrospun scaffolds (ES-Ss), highlighting their structural, mechanical, and biological properties. Additionally, it explores their diverse in vitro and in vivo outcomes across multiple tissue types, including bone, cartilage, skin, cardiac, and neural tissues. This study further addresses current challenges and future perspectives to optimize PHB-based scaffolds for clinical translation in regenerative medicine.</p>","PeriodicalId":7372,"journal":{"name":"Advances in Polymer Technology","volume":"2026 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/adv/3728039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148173929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}