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Journal of clinical and translational pathology最新文献

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Pseudotumor Associated with a Bioabsorbable Screw in a Patient with Reconstructed Congenital Absence of the Anterior Cruciate Ligament: a Case report 假肿瘤合并生物可吸收螺钉治疗先天性前交叉韧带缺损1例
Journal of clinical and translational pathology Pub Date : 2022-12-15 DOI: 10.14218/jctp.2022.00024
Yaxia Zhang, T. Bauer, S. Rodeo
{"title":"Pseudotumor Associated with a Bioabsorbable Screw in a Patient with Reconstructed Congenital Absence of the Anterior Cruciate Ligament: a Case report","authors":"Yaxia Zhang, T. Bauer, S. Rodeo","doi":"10.14218/jctp.2022.00024","DOIUrl":"https://doi.org/10.14218/jctp.2022.00024","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45094395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Review and Update on Epithelial Tumors of the Anal Canal 肛管上皮性肿瘤的研究进展
Journal of clinical and translational pathology Pub Date : 2022-12-13 DOI: 10.14218/jctp.2022.00027
Xiaoyan Liao
{"title":"A Review and Update on Epithelial Tumors of the Anal Canal","authors":"Xiaoyan Liao","doi":"10.14218/jctp.2022.00027","DOIUrl":"https://doi.org/10.14218/jctp.2022.00027","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45660409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prognosis and Immunotherapy Prediction Based on Immunogenic Cell Death-related lncRNA in Gastric Cancer 基于免疫原性细胞死亡相关lncRNA的癌症预后及免疫治疗预测
Journal of clinical and translational pathology Pub Date : 2022-12-08 DOI: 10.14218/jctp.2022.00022
Qinian Jiang, Zhengshan Liu, Hang Yang
{"title":"Prognosis and Immunotherapy Prediction Based on Immunogenic Cell Death-related lncRNA in Gastric Cancer","authors":"Qinian Jiang, Zhengshan Liu, Hang Yang","doi":"10.14218/jctp.2022.00022","DOIUrl":"https://doi.org/10.14218/jctp.2022.00022","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49584921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Clinical Significance of the Positive Surgical Margin and Dominant Tumor Laterality Following Radical Prostatectomy: A Retrospective Study 前列腺癌根治术后手术切缘阳性和显性肿瘤侧位的临床意义：回顾性研究
Journal of clinical and translational pathology Pub Date : 2022-11-22 DOI: 10.14218/jctp.2022.00023
Shulin Wu, Sharron X. Lin, G. Wirth, Alexander O. Subtelny, Min Lu, Jian Lu, Zongwei Wang, A. Olumi, D. Dahl, M. Blute, Chin-Lee Wu
{"title":"The Clinical Significance of the Positive Surgical Margin and Dominant Tumor Laterality Following Radical Prostatectomy: A Retrospective Study","authors":"Shulin Wu, Sharron X. Lin, G. Wirth, Alexander O. Subtelny, Min Lu, Jian Lu, Zongwei Wang, A. Olumi, D. Dahl, M. Blute, Chin-Lee Wu","doi":"10.14218/jctp.2022.00023","DOIUrl":"https://doi.org/10.14218/jctp.2022.00023","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46346717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High Frequency of HES1 Loss in Colorectal Adenocarcinomas with RAS/BRAF Mutations 具有RAS/BRAF突变的结直肠癌中HES1的高频率缺失
Journal of clinical and translational pathology Pub Date : 2022-10-27 DOI: 10.14218/jctp.2022.00020
W. Chen, Lan Zhou, Wei Xin
{"title":"High Frequency of HES1 Loss in Colorectal Adenocarcinomas with RAS/BRAF Mutations","authors":"W. Chen, Lan Zhou, Wei Xin","doi":"10.14218/jctp.2022.00020","DOIUrl":"https://doi.org/10.14218/jctp.2022.00020","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48514651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Histopathological Evaluation of Recurrent Primary Biliary Cholangitis after Liver Transplantation 肝移植术后复发性原发性胆总管炎的组织病理学评价
Journal of clinical and translational pathology Pub Date : 2022-09-28 DOI: 10.14218/jctp.2022.00021
Wegahta Weldemichael, Dongwei Zhang, Jingmei Lin
{"title":"Histopathological Evaluation of Recurrent Primary Biliary Cholangitis after Liver Transplantation","authors":"Wegahta Weldemichael, Dongwei Zhang, Jingmei Lin","doi":"10.14218/jctp.2022.00021","DOIUrl":"https://doi.org/10.14218/jctp.2022.00021","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44417046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Entities and Emerging Issues in Gastrointestinal and Liver Pathology 胃肠道和肝脏病理学中罕见的实体和新出现的问题
Journal of clinical and translational pathology Pub Date : 2022-09-28 DOI: 10.14218/jctp.2022.00025
F. Yin, Huamin Wang
{"title":"Rare Entities and Emerging Issues in Gastrointestinal and Liver Pathology","authors":"F. Yin, Huamin Wang","doi":"10.14218/jctp.2022.00025","DOIUrl":"https://doi.org/10.14218/jctp.2022.00025","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42216797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Elevated Serum Soluble Triggering Receptor Expressed on Myeloid Cells-1 with 90-day Outcomes of Patients with Acute-on-chronic Liver Failure: A Cohort Study 骨髓细胞-1表达的血清可溶性触发受体升高与急慢性肝功能衰竭患者90天预后的相关性：一项队列研究
Journal of clinical and translational pathology Pub Date : 2022-09-27 DOI: 10.14218/jctp.2022.00015
Yue Huang, Jun-Jun Cai, T. Han
{"title":"Association of Elevated Serum Soluble Triggering Receptor Expressed on Myeloid Cells-1 with 90-day Outcomes of Patients with Acute-on-chronic Liver Failure: A Cohort Study","authors":"Yue Huang, Jun-Jun Cai, T. Han","doi":"10.14218/jctp.2022.00015","DOIUrl":"https://doi.org/10.14218/jctp.2022.00015","url":null,"abstract":"","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48373241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Goblet Cell Adenocarcinoma of the Appendix: Diagnosis, Prognosis and Nomenclature 阑尾杯状细胞腺癌的诊断、预后及命名
Journal of clinical and translational pathology Pub Date : 2022-09-06 DOI: 10.14218/jctp.2022.00018
Hanlin L. Wang
{"title":"Goblet Cell Adenocarcinoma of the Appendix: Diagnosis, Prognosis and Nomenclature","authors":"Hanlin L. Wang","doi":"10.14218/jctp.2022.00018","DOIUrl":"https://doi.org/10.14218/jctp.2022.00018","url":null,"abstract":"Goblet cell adenocarcinoma (GCA) is a new name for goblet cell carcinoid used by the fifth edition of the World Health Organization Classification of Tumors of the Digestive Sys- tem published in 2019. This name change put an end to the years’ name confusion and led to the simplification and standardization of the diagnostic criteria and grading system for this unique epithelial neoplasm almost exclusively occur- ring in the appendix. This is extremely important because accurate diagnosis and grading are essential to patient man- agement and prognostication. Under this new name, GCA is recognized to have low-grade and high-grade components with variable proportions. As such, the presence of the low-grade components is required for the diagnosis, but the pro- portion of the high-grade components dictates the prognosis. With regard to the nomenclature, GCA does not seem to be an ideal name for this tumor because goblet cells are ap-parently not the cell origin nor the unique cell population of the tumor. While the histogenesis remains ambiguous, the name “crypt","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42323496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune Checkpoint Inhibitor-Induced Hepatic Injury: A Clinicopathologic Review. 免疫检查点抑制剂诱发的肝损伤：临床病理学回顾
Journal of clinical and translational pathology Pub Date : 2022-09-01 Epub Date: 2022-09-26 DOI: 10.14218/jctp.2022.00017
Mehran Taherian, Deyali Chatterjee, Huamin Wang
{"title":"Immune Checkpoint Inhibitor-Induced Hepatic Injury: A Clinicopathologic Review.","authors":"Mehran Taherian, Deyali Chatterjee, Huamin Wang","doi":"10.14218/jctp.2022.00017","DOIUrl":"10.14218/jctp.2022.00017","url":null,"abstract":"<p><p>Although immune checkpoint inhibitors (ICIs) have been a revolutionary milestone in immuno-oncology, immune-related adverse events (irAEs) may occur due to enhanced T cell activation and immune dysregulation. The irAEs can occur as early as within days to reportedly as late as up to 26 weeks. They may affect any organ system in the body, most commonly the luminal gastrointestinal tract, liver, skin, endocrine system, and lungs. The mechanisms of irAEs are complex and have not been fully understood. A breach of self-tolerance, which leads to autoantigen reactivity due to the enhanced activation and infiltration of T cells or the production of autoantibodies, and a non-specific autoinflammatory mechanism have been proposed. Limited data is available on the clinical and pathologic features of ICI-induced liver injury. This review presents an overview of the clinical and common histopathologic features and patterns of ICI-induced liver injury, the differential diagnoses, and the clinical management. Available data suggest that the histopathologic findings of ICI-induced hepatic injury are often non-specific and overlap with other challenging differential diagnoses. Therefore, a good knowledge of the histopathologic spectrum of ICI-induced hepatic injury and their differential diagnoses combined with the serological test results, clinical correlation, and communication with the clinical team is necessary to make an accurate and timely diagnosis.</p>","PeriodicalId":73661,"journal":{"name":"Journal of clinical and translational pathology","volume":"2 3","pages":"83-90"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d2/cd/nihms-1844355.PMC9815477.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10514988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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