Joint diseases and related surgery最新文献

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Frailty as a predictor of vertebral fractures in osteoporosis: A clinical perspective. 虚弱作为骨质疏松症椎体骨折的预测因子:临床观点。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-04-05 DOI: 10.52312/jdrs.2025.2202
Zeynep Şahiner, Merve Güner, Özgür Selim Uysal
{"title":"Frailty as a predictor of vertebral fractures in osteoporosis: A clinical perspective.","authors":"Zeynep Şahiner, Merve Güner, Özgür Selim Uysal","doi":"10.52312/jdrs.2025.2202","DOIUrl":"10.52312/jdrs.2025.2202","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to assess the correlation between vertebral compression fractures (VCFs) and frailty and to identify the possible link between the number of VCFs and frailty intensity in patients with osteoporosis (OP).</p><p><strong>Patients and methods: </strong>Between January 2025 and February 2025, a total of 204 patients (143 males, 61 females; mean age: 71.8±5.5 years; range, 65 to 89 years) over 65 years who received treatment for OP in the inpatient setting were included. The patients were divided into two groups according to their Clinical Frailty Scale (CFS) scores as the frail group (n=141, CFS ≥4) and the non-frail group (n=63, CFS <4). Demographic and clinical characteristics, geriatric syndromes, and fracture prevalence were recorded.</p><p><strong>Results: </strong>The handgrip strength was significantly reduced in the frail group (19 kg vs. 21 kg, p=0.004), with a probable sarcopenia rate of 42% (p=0.034). The rate of participants with no fractures, a single fracture, and multiple fractures was 42%, 26%, and 22% in the non-frail group, compared to 57%, 73%, and 77% in the frail group, respectively (p=0.018). This difference was particularly evident in patients with multiple fractures (odds ratio [OR]=2.34, 95% confidence interval [CI]: 1.13-4.87, p=0.023).</p><p><strong>Conclusion: </strong>Frailty is strongly associated with a higher incidence of VCFs and multiple fractures in older individuals with OP.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"408-414"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the performance of ChatGPT-4o on the Turkish Orthopedics and Traumatology Board Examination. 评估chatgpt - 40在土耳其骨科和创伤学委员会考试中的表现。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-04-05 DOI: 10.52312/jdrs.2025.1958
Hilal Yağar, Ender Gümüşoğlu, Zeynel Mert Asfuroğlu
{"title":"Assessing the performance of ChatGPT-4o on the Turkish Orthopedics and Traumatology Board Examination.","authors":"Hilal Yağar, Ender Gümüşoğlu, Zeynel Mert Asfuroğlu","doi":"10.52312/jdrs.2025.1958","DOIUrl":"10.52312/jdrs.2025.1958","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to assess the overall performance of ChatGPT version 4-omni (GPT-4o) on the Turkish Orthopedics and Traumatology Board Examination (TOTBE) using actual examinees as a reference point to evaluate and compare the performance of GPT-4o with that of human participants.</p><p><strong>Materials and methods: </strong>In this study, GPT-4o was tested with multiple-choice questions that formed the first step of 14 TOTBEs conducted between 2010 and 2023. The assessment of image-based questions was conducted separately for all exams. The questions were classified based on the subspecialties for the five exams (2010-2014). The performance of GPT-4o was assessed and compared to those of actual examinees of the TOTBE.</p><p><strong>Results: </strong>The mean total score of GPT-4o was 70.2±5.64 (range, 61 to 84), whereas that of actual examinees was 58±3.28 (range, 53.6 to 64.6). Considering accuracy rates, GPT-4o demonstrated 62% accuracy on image-based questions and 70% accuracy on text-based questions. It also demonstrated superior performance in the field of basic sciences, whereas actual examinees performed better in the specialty of reconstruction. Both GPT-4o and actual examinees exhibited the lowest scores in the subspecialty of lower extremity and foot.</p><p><strong>Conclusion: </strong>Our study results showed that GPT-4o performed well on the TOTBE, particularly in basic sciences. While it demonstrated accuracy comparable to actual examinees in some areas, these findings highlight its potential as a helpful tool in medical education.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"304-310"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guyon's canal syndrome caused by mass effect after chronic dog bite hand injury. 慢性犬咬伤手后肿块效应所致盖恩管综合征。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-04-05 DOI: 10.52312/jdrs.2025.2136
Jangyoun Choi, Jun Hyeok Lee, Young Joon Jun, Jong Yun Choi
{"title":"Guyon's canal syndrome caused by mass effect after chronic dog bite hand injury.","authors":"Jangyoun Choi, Jun Hyeok Lee, Young Joon Jun, Jong Yun Choi","doi":"10.52312/jdrs.2025.2136","DOIUrl":"10.52312/jdrs.2025.2136","url":null,"abstract":"<p><p>Epidermal inclusion cysts are defined as dermal or subcutaneous epithelial cysts which are filled with keratin and lined with true epidermis. Although exceedingly rare, they can lead to pathological conditions, such as nerve compression syndrome. To the best of our knowledge, this is the first documented case of a 59-year-old woman with ulnar nerve compression at the wrist due to dog bite hand injury. An epidermal inclusion cyst was located adjacent to the ulnar nerve, resulting in significant compression. Notably, no direct connection was observed between the cyst and ulnar nerve. Surgical resection of the cyst led to complete resolution of tingling in the patient's middle and ring fingers. Although uncommon compared to the frequently reported causes of ulnar neuropathy, epidermal inclusion cysts should be considered as a differential diagnosis, particularly in patients with a history of repetitive wrist motion and trauma. A comprehensive diagnostic approach and tailored surgical interventions are needed to ensure good clinical outcomes in such cases.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"456-460"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hidden blood loss of percutaneous vertebroplasty for osteoporotic vertebral compression fractures. 经皮椎体成形术治疗骨质疏松性椎体压缩性骨折的隐蔽性失血。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-04-05 DOI: 10.52312/jdrs.2025.2201
Lu Tang, Huai Zhang, Yun Yang, Hua-Qiang Huang
{"title":"Hidden blood loss of percutaneous vertebroplasty for osteoporotic vertebral compression fractures.","authors":"Lu Tang, Huai Zhang, Yun Yang, Hua-Qiang Huang","doi":"10.52312/jdrs.2025.2201","DOIUrl":"10.52312/jdrs.2025.2201","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to evaluate the amount of hidden blood loss (HBL) in patients treated with percutaneous vertebroplasty (PVP) for thoracolumbar osteoporotic vertebral compression fractures (OVCFs) and to compare the HBL between unilateral extrapedicular approach and unilateral transpedicular approach.</p><p><strong>Patients and methods: </strong>Between February 2022 to February 2023, a total of 136 patients (49 males, 87 females; mean age: 76.4±9.5 years; range, 55 to 100 years) with thoracolumbar OVCFs treated with PVP were retrospectively analyzed. Patients who underwent unilateral transpedicular approach were divided into Group A (n=62) and patients who underwent unilateral extrapedicular approach were divided into Group B (n=74). Demographic results and clinical data were collected and compared between the two groups. The HBL was calculated according to the Sehat formula.</p><p><strong>Results: </strong>The mean operation duration was 31.7±9.9 min in Group A and 29.1±11.1 in Group B, indicating no statistically significant difference between the groups (p=0.159). The mean volume of bone cement instilled was 4.4±0.4 mL in Group A and 4.7±0.6 mL in Group B. The volume of cement injected in Group A was less than that of Group B (p=0.001). The mean hemoglobin loss and the amount of HBL were significantly lower in Group A than Group B (p=0.001 and p=0.040, respectively).</p><p><strong>Conclusion: </strong>Our study results suggest that perioperative HBL cannot be ignored in PVP for thoracolumbar OVCFs, regardless of the surgical approach chosen. We should be more concerned about anemia in patients with thoracolumbar OVCFs after unilateral extrapedicular approach compared to the unilateral transpedicular approach.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"240-247"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086476/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of high large unstained cell percentages in ongoing inflammation in the intercritical gout. 高未染色细胞百分比在临界间痛风持续炎症中的作用。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-04-05 DOI: 10.52312/jdrs.2025.2188
Rezan Koçak Ulucaköy Rezan Koçak Ulucaköy Rezan Koçak Ulucaköy, Esra Kayacan Erdoğan, Kevser Orhan, Elif Kübra Gürler, Ebru Atalar, Bahar Özdemir Ulusoy, Hakan Babaoğlu, Berkan Armağan, İsmail Dogan, Serdar Can Güven
{"title":"The role of high large unstained cell percentages in ongoing inflammation in the intercritical gout.","authors":"Rezan Koçak Ulucaköy Rezan Koçak Ulucaköy Rezan Koçak Ulucaköy, Esra Kayacan Erdoğan, Kevser Orhan, Elif Kübra Gürler, Ebru Atalar, Bahar Özdemir Ulusoy, Hakan Babaoğlu, Berkan Armağan, İsmail Dogan, Serdar Can Güven","doi":"10.52312/jdrs.2025.2188","DOIUrl":"10.52312/jdrs.2025.2188","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate whether large unstained cells (LUCs) is a marker of inflammation in gout patients and whether it is associated with different clinical conditions such as erosion, tophus, intercritical period, and gout flare.</p><p><strong>Patients and methods: </strong>Between November 2022 and May 2023, a total of 100 consecutive adult gout patients (81 males, 19 females; mean age 53.8±12.8 years; range, 21 to 79 years) and 30 healthy controls (24 males, 6 females; mean age 57.2±10.6 years; range, 28 to 75) were included in this cross-sectional study. Data including demographics, clinical characteristics, laboratory results and direct radiography images of affected joints at the most recent visit were recorded.</p><p><strong>Results: </strong>Leukocyte counts were found to be significantly higher in gout patients (p=0.048). The LUC counts and percentages and levels of acute phase reactants were similar between the patient and control groups (p=0.401, p=0.668, p=0.222, and p=0.505, respectively). In subgroup analyses of the gout patients, there were no significant differences in LUC counts and percentages between those with tophaceous disease (p=0.650 and p=0.388, respectively), erosions (p=0.154 and p=0.137, respectively) and elevated serum uric acid levels (p=0.918 and p=0.196, respectively). However, LUC percentages were statistically significantly higher in patients without elevated C-reactive protein (CRP) and in the intercritical gout (p=0.039 and p=0.05, respectively).</p><p><strong>Conclusion: </strong>Our study results showed similar LUC counts and percentages between the gout patients and healthy controls. However, in the subgroup analysis of the gout patients, the LUC percentages were observed to be significantly higher in those without high CRP levels and in patients with intercritical gout. This finding may suggest that subclinical inflammation persists in intercritical gout.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"366-372"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glove-like hand: A case of severe-circumferential hand degloving injury. 手套样手:严重环向手脱手套伤1例。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-04-05 DOI: 10.52312/jdrs.2025.2131
Çağdaş Pamuk, Meriç Uğurlar, Ülker Moralar
{"title":"Glove-like hand: A case of severe-circumferential hand degloving injury.","authors":"Çağdaş Pamuk, Meriç Uğurlar, Ülker Moralar","doi":"10.52312/jdrs.2025.2131","DOIUrl":"10.52312/jdrs.2025.2131","url":null,"abstract":"<p><p>While limb amputations are a common and routine procedure for hand surgery, degloving injuries to the hand and fingers are less common and challenging for many surgeons. For degloving injuries which mostly result in limb loss, amputation has been recommended in previous studies and established classification systems, if there is a total avulsion injury. In this article, we present a replantation case in which all difficult microsurgical techniques were used in an injury where four fingers were degloved like a glove and accompanied by a second-degree burn that would prevent flap applications along the dorsum of the forearm. We also performed a detailed analysis of a rare clinical image. In conclusion, many treatment options have been described for degloving injuries, such as flaps and skin-grafting, the most optimal functional and cosmetic results can be achieved with replantation. Therefore, the first option should be replantation, if possible, but in case of failure, other surgical options should be evaluated without delay.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"472-478"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound-guided nerve hydrodissection for sciatic neuropathy caused by piriformis rhabdomyolysis: A case report. 超声引导下神经水解剖治疗梨状肌横纹肌溶解性坐骨神经病变1例。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-04-05 DOI: 10.52312/jdrs.2025.2183
Gi Young Park, Jae Ik Jung, Kang Lip Kim Kang Lip Kim Kang Lip Kim
{"title":"Ultrasound-guided nerve hydrodissection for sciatic neuropathy caused by piriformis rhabdomyolysis: A case report.","authors":"Gi Young Park, Jae Ik Jung, Kang Lip Kim Kang Lip Kim Kang Lip Kim","doi":"10.52312/jdrs.2025.2183","DOIUrl":"10.52312/jdrs.2025.2183","url":null,"abstract":"<p><p>Peripheral entrapment neuropathy is a rare complication of rhabdomyolysis and lacks successful treatment. In this article, we report a case of sciatic neuropathy caused by piriformis rhabdomyolysis which was successfully treated with ultrasound-guided sciatic nerve hydrodissection. A 27-year-old male patient with left buttock pain and left lower limb weakness received ultrasound-guided nerve hydrodissection via injection of dexamethasone and 5% dextrose water into the area surrounding the left sciatic nerve. After injection, the patient's pain and left lower extremity weakness subsided. In conclusion, although peripheral entrapment neuropathy due to rhabdomyolysis is rare, early diagnosis and treatment using ultrasound-guided nerve hydrodissection may yield favorable clinical outcomes.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"461-466"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare cause of knee pain: Multiple intraosseous lipomas mimicking bone metastasis. 膝关节疼痛的罕见原因:多发性骨内脂肪瘤模拟骨转移。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-04-05 DOI: 10.52312/jdrs.2025.2017
Hatice Betigul Meral, Mehmet Agirman
{"title":"A rare cause of knee pain: Multiple intraosseous lipomas mimicking bone metastasis.","authors":"Hatice Betigul Meral, Mehmet Agirman","doi":"10.52312/jdrs.2025.2017","DOIUrl":"10.52312/jdrs.2025.2017","url":null,"abstract":"<p><p>Intraosseous lipomas (IOLs) are rare benign bone tumors which can closely mimic malignancy on imaging, leading to diagnostic challenges. A 34-year-old male patient was admitted with persistent knee pain which was initially suspected to be metastatic bone disease. The patient reported activity-related pain relieved by rest. Physical examination revealed mild tenderness without swelling or restricted motion. Laboratory findings, including serum calcium and inflammatory markers, were normal. Magnetic resonance imaging (MRI) showed hyperintense lesions in the tibial and femoral metaphyses with surrounding bone marrow edema, raising suspicion of malignancy. Bone scintigraphy revealed increased radionuclide uptake in the tibial tuberosity, iliac crest, and the ninth rib, further mimicking metastatic disease. A biopsy of the tibial lesion confirmed mature adipocytes without necrosis or atypia, diagnosing IOLs. The patient was managed conservatively with non-steroidal anti-inflammatory drugs and physiotherapy. At three months, symptoms resolved completely, with no recurrence or new complaints. Follow-up MRI confirmed lesion stability. In conclusion, this case highlights the diagnostic complexity of IOLs and emphasizes the need for multimodal imaging and histopathological confirmation to differentiate benign lesions from malignancies. Including IOLs in the differential diagnosis of unexplained bone pain can prevent unnecessary invasive procedures and mistreatment.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"467-471"},"PeriodicalIF":1.9,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proximal partial fibular resection versus high tibial osteotomy: Comparative outcomes in early-stage knee osteoarthritis. 近端部分腓骨切除术与胫骨高位截骨术:早期膝关节骨关节炎的比较结果。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-02-07 DOI: 10.52312/jdrs.2025.2107
Emre Gultac, Fatih İlker Can, Nevres Hürriyet Aydoğan
{"title":"Proximal partial fibular resection versus high tibial osteotomy: Comparative outcomes in early-stage knee osteoarthritis.","authors":"Emre Gultac, Fatih İlker Can, Nevres Hürriyet Aydoğan","doi":"10.52312/jdrs.2025.2107","DOIUrl":"10.52312/jdrs.2025.2107","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare the clinical and radiographic outcomes of proximal partial fibular resection (PPFR) and opening-wedge high tibial osteotomy (OWHTO) in middle-aged patients with early-stage medial compartment knee osteoarthritis (OA).</p><p><strong>Patients and methods: </strong>Between January 2017 and January 2023, a total of 90 patients (47 males, 43 females; mean age: 50.9±5.8 years; range, 40 to 59 years) who underwent PPFR or OWHTO for early-stage medial compartment knee OA were retrospectively analyzed. The patients were divided into two groups based on the surgical technique: Group 1 (n=48) included those who underwent PPFR, while Group 2 (n=42) comprised those treated with OWHTO. Clinical outcomes were evaluated using the Visual Analog Scale (VAS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Radiographic measurements included femorotibial angle (FTA) and lateral joint space (LJS).</p><p><strong>Results: </strong>Both procedures demonstrated a significant improvement in function and pain. The mean postoperative FTA change was greater in the OWHTO group (7.69±1.35°) compared to the PPFR group (2.87±1.24°, p=0.001). The mean LJS changes were not statistically significant between the groups. Postoperative WOMAC and VAS scores improved in both groups, indicating no significant difference. Minor complications included transient peroneal nerve symptoms in the PPFR group, which resolved spontaneously at three months postoperatively.</p><p><strong>Conclusion: </strong>Both PPFR and OWHTO are effective surgical options for early-stage medial compartment knee OA. While OWHTO offers superior mechanical correction, PPFR provides a less invasive alternative with similar functional outcomes.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"266-271"},"PeriodicalIF":1.9,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of ozone therapy in the treatment of frozen shoulder in rats: An experimental study. 臭氧疗法治疗大鼠肩周炎的实验研究。
IF 1.9
Joint diseases and related surgery Pub Date : 2025-01-20 DOI: 10.52312/jdrs.2025.2055
Ekin Kaya Simsek, Duygu Turkbey Simsek, Deniz Mert Ayan, Coskun Araz, Bahtiyar Haberal
{"title":"Efficacy of ozone therapy in the treatment of frozen shoulder in rats: An experimental study.","authors":"Ekin Kaya Simsek, Duygu Turkbey Simsek, Deniz Mert Ayan, Coskun Araz, Bahtiyar Haberal","doi":"10.52312/jdrs.2025.2055","DOIUrl":"10.52312/jdrs.2025.2055","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to explore the therapeutic effects of medical ozone therapy on the frozen shoulder (FS) model and compares it with traditional corticosteroid treatments in rats.</p><p><strong>Materials and methods: </strong>A total of 30 Sprague-Dawley rats aged 18 to 20 months weighing between 400 to 450 g were included in the study. The rats were randomly divided into three equal groups: a control group (C, n=10, FS model only), a corticosteroid treatment group (CST, n=10, FS model + intraarticular 0.5 mg/kg betamethasone), and an ozone treatment group (OT, n=10, FS model + intraarticular 1 mg/kg ozone). Frozen shoulder was induced via surgical immobilization, and treatments were administered intraarticularly. Outcomes were measured through histopathological and functional assessments.</p><p><strong>Results: </strong>The CST and OT significantly reduced inflammation (p<0.001), capillary proliferation (p<0.001), fibroblastic proliferation (p=0.002), collagen type 3 staining (p=0.022), and mean capsular thickness (p<0.001), while improving the range of motion in all directions compared to the control group. Ozone therapy showed a comparable reduction in fibrosis and improvement in joint mobility to CST (p=0.001).</p><p><strong>Conclusion: </strong>Ozone therapy effectively reduces fibrosis and improves mobility in an FS rat model, presenting a promising alternative to corticosteroids. However, further studies are still needed to elucidate the molecular mechanisms and optimize treatment protocols, underscoring the potential for future discoveries in this area.</p>","PeriodicalId":73560,"journal":{"name":"Joint diseases and related surgery","volume":"36 2","pages":"272-282"},"PeriodicalIF":1.9,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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