JMIR dermatology最新文献

{"title":"Acral Persistent Papular Mucinosis in the United States: Case Series and Literature Review.","authors":"Devin Miller, Rachel Manci, Jay Patel, William Guo, Daniel Lozeau, James Briley","doi":"10.2196/77714","DOIUrl":"10.2196/77714","url":null,"abstract":"<p><strong>Background: </strong>Acral persistent papular mucinosis (APPM) is a localized variant of lichen myxedematosus (LM) characterized by asymptomatic, flesh-colored papules primarily distributed on the hands and forearms. This chronic dermatosis, distinct from generalized mucinosis due to its lack of systemic involvement, remains underreported in medical literature.</p><p><strong>Objective: </strong>In this study, we present two cases of APPM to the limited pool of documented cases in the United States, highlighting its emerging recognition.</p><p><strong>Methods: </strong>This is a case series of two patients presenting with asymptomatic papular eruptions on the hands and wrists, consistent with the typical presentation of APPM. Diagnostic confirmation via biopsy revealed focal cutaneous mucinosis. Comprehensive laboratory evaluations, including serum and urine protein electrophoresis, showed no evidence of underlying gammopathy in either patient.</p><p><strong>Results: </strong>Treatment modalities for APPM are limited and often ineffective. Unlike other forms of LM, APPM features are confined to skin lesions, posing primarily as a cosmetic concern with a favorable prognosis. Accurate diagnosis of this localized LM is crucial to differentiate it from the more severe, generalized form, scleromyxedema, which can have organ involvement and may become fatal. Notably, while spontaneous resolution is reported in LM, including discrete papular mucinosis, APPM typically persists without resolution even after extended follow-up.</p><p><strong>Conclusions: </strong>These cases underscore the importance of recognizing APPM and advocating for broader awareness and exploration of its clinical variability, etiology, and management strategies. With increasing recognition, the understanding of APPM can be enhanced, paving the way for optimized management and improved outcomes for affected individuals.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e77714"},"PeriodicalIF":0.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a Large Language Model as a Dermatology Case Narrator: Exploring the Dynamics of a Chatbot as an Educational Tool in Dermatology.","authors":"Emmanouil Karampinis, Dafni Anastasia Bozi Tzetzi, Georgia Pappa, Dimitra Koumaki, Dimitrios Sgouros, Efstratios Vakirlis, Aikaterini Liakou, Markos Papakonstantis, Marios Papadakis, Dimitrios Mantzaris, Elizabeth Lazaridou, Enzo Errichetti, Cristian Navarrete-Dechent, Angeliki Victoria Roussaki Schulze, Alexandros Katoulis","doi":"10.2196/72058","DOIUrl":"10.2196/72058","url":null,"abstract":"<p><strong>Unlabelled: </strong>A comparison of dermatological cases generated by artificial intelligence (AI) versus those created without AI by medical students revealed that AI-created cases were characterized by detailed case descriptions, analysis of medical history, and clinical examinations, but lacked the depth, clinical relevance, and motivational elements found in non-AI cases, which were shorter, presented clinical dilemmas, and included challenging scenarios that students found more educational and engaging.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e72058"},"PeriodicalIF":0.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Perceptions of Artificial Intelligence and Telemedicine in Dermatology: Narrative Review.","authors":"Charlotte McRae, Ting Dan Zhang, Leslie Donoghue Seeley, Michael Anderson, Laci Turner, Lauren V Graham","doi":"10.2196/75454","DOIUrl":"10.2196/75454","url":null,"abstract":"<p><strong>Background: </strong>Artificial intelligence (AI) and telemedicine have significant potential to transform dermatology care delivery, but patient perspectives on these technologies have not been systematically compared.</p><p><strong>Objective: </strong>This study aimed to examine patient perspectives on AI and telemedicine in dermatology to inform implementation strategies as these technologies increasingly converge in clinical practice.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted using PubMed, Scopus, and Embase databases between August 2024 and October 2024. We identified 48 papers addressing patient perspectives on AI and telemedicine in dermatology, with none directly comparing patients' views of both technologies.</p><p><strong>Results: </strong>Several distinct themes emerged regarding patient perspectives on these technologies: willingness to use, perceived benefits and risks, barriers to implementation, and conditions necessary for successful integration. Findings revealed that patients express hesitancy toward AI-based diagnoses that lack dermatologist involvement, while preferences for teledermatology varied by reason for appointment, age, and previous technology exposure. Patients' motivations for implementing AI are connected to its potential for quicker diagnoses and improved triage efficiency. At the same time, telemedicine addresses logistical challenges such as reduced travel time and improved appointment availability. Both technologies were perceived to improve accessibility and diagnostic efficiency, though patients expressed concerns about AI's limited communication abilities and teledermatology's inability to perform physical examinations. Primary adoption barriers for these modalities included technological limitations and trust concerns, with patients emphasizing the need for dermatologist oversight, transparency, and adequate educational resources for successful integration.</p><p><strong>Conclusions: </strong>The complementary strengths of AI and teledermatology suggest they could mitigate each other's limitations when integrated-AI potentially enhancing teledermatology's diagnostic accuracy, while teledermatology addresses AI's lack of human connection. By thoroughly examining these perspectives, this review may serve as a guide for the patient-centered integration of technology in the future landscape of accessible dermatologic care.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e75454"},"PeriodicalIF":0.0,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of Reddit Posts About Xylazine-Associated Wounds: Qualitative Study.","authors":"Anthony Spadaro, JaMor Hairston, Sahithi Lakamana, Rachel Wightman, Jennifer Love, Jeanmarie Perrone, Abeed Sarker","doi":"10.2196/70329","DOIUrl":"10.2196/70329","url":null,"abstract":"<p><strong>Background: </strong>Xylazine has been associated with skin wounds. The rising prevalence of xylazine and its debated role in wound causation have sparked concerns among public health professionals, medical experts, and people who use drugs.</p><p><strong>Objective: </strong>This study used a qualitative evaluation of Reddit posts to understand the experiences of people who use drugs concerning xylazine-associated wounds.</p><p><strong>Methods: </strong>This study explored xylazine discussions on Reddit. Data were collected from 930+ drug-related subreddits via the PRAW Python application programming interface, and natural language processing methods were employed to identify posts that mentioned xylazine and wound-related keywords. Retrieved posts were manually coded for thematic analysis, and a term frequency-inverse document frequency analysis was performed per theme to obtain additional insights.</p><p><strong>Results: </strong>The manual classification of 286 posts revealed predominant themes related to the pathophysiology of xylazine, wound locations on the body, and management strategies. The 3 most frequent xylazine wound-related themes were \"Mechanisms of xylazine-associated wounds\" (84 posts, 29.4%), \"Geographic region\" (67, 23.4%), and \"Location of wounds on the body\" (56, 19.6%). The analysis showed xylazine's presence in the discussions among Reddit's drug-using communities, with a notable focus on wound management and geographic trends. The term frequency-inverse document frequency analysis revealed prominent lexical markers within each theme.</p><p><strong>Conclusions: </strong>The findings suggest that social media platforms such as Reddit can serve as valuable resources for understanding emerging health issues such as xylazine-associated wounds. The study's findings highlight patterns of use, the characteristics of wounds on people who use drugs, and discussions about wound management. This study adds to a growing body of literature using social media to understand the consequences of emerging drugs on human health.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e70329"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12434632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Omission of Risk in Vitamin A-Related Dermatologic Instagram Posts: A Growing Concern in an Unregulated Digital Landscape.","authors":"Robert John Vanaria, Michael Povelaitis, Riya Khokhal, Shannon Meledathu, Claudia Green, Robin Ashinoff, Mariela Mitre","doi":"10.2196/77504","DOIUrl":"10.2196/77504","url":null,"abstract":"<p><strong>Unlabelled: </strong>We reviewed 30 of the top-viewed Instagram videos using the hashtags #retinoid and #retinol to assess reliability using the DISCERN instrument. Dermatologists produced more accurate content than laypeople, though important details such as treatment risks were often omitted. Our findings highlight the need for health professionals to balance accessibility with accuracy to provide trustworthy dermatologic information on social media.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e77504"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12434146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145056447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermal Filler Use in Patients Undergoing Chemotherapy and Radiation Therapy.","authors":"Mia Panlilio, Elizabeth Tchernogorova, Binh Minh Nguyen, Sana Khan, Leslie Torgerson","doi":"10.2196/76898","DOIUrl":"10.2196/76898","url":null,"abstract":"<p><strong>Unlabelled: </strong>Dermal fillers have gained increasing popularity for their ability to enhance facial symmetry, restore volume, and improve skin texture. However, their use in patients with cancer undergoing active chemotherapy and radiation therapy poses unique challenges, as these treatments can alter both the safety profile and efficacy of filler procedures. Chemotherapy can interfere with normal wound healing and immune responses, warranting a more cautious and individualized approach when considering dermal fillers in this population. Although rare, dermal fillers have been associated with adverse outcomes in a limited number of diseases, including cellulitis, autoimmune/inflammatory syndrome induced by adjuvants, and a possible predisposition to malignancy. Other effects include localized inflammatory, systemic hypersensitivity, and delayed granulomatous formation, and these could be more severe in patients undergoing antineoplastic therapy. Furthermore, chemotherapy is often paired with adjuvant radiation therapy in cancer treatment, making it important to note the potential changes radiation can have on the skin. More research is needed to examine the direct interactions of chemotherapy and radiation on various filler materials injected within the skin, and how these can alter one's risk of adverse effects. The lack of research on this topic further emphasizes that clinicians should thoroughly educate patients receiving chemotherapy and adjuvant radiation treatment about the heightened potential risks associated with dermal filler injections and treatment regimens should be planned accordingly to minimize any adverse events.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e76898"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Online Resources for Hidradenitis Suppurativa for Patient Use: Systematic Search and Analysis.","authors":"Emily Sheetz, Aryn A Alanizi, Joshua Edwards, Alice A Roberts","doi":"10.2196/72773","DOIUrl":"https://doi.org/10.2196/72773","url":null,"abstract":"<p><strong>Unlabelled: </strong>This research letter evaluates the quality and readability of hidradenitis suppurativa (HS) websites found on Google and Bing with the DISCERN instrument and Flesch-Kincaid Readability metrics. Comprehensive and reliable articles can lead to increased knowledge about HS and further enhance physician-patient relationships and shared decision-making. This study's aim was to identify reliable resources to help bridge knowledge gaps and support informed discussions on management and treatment options.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e72773"},"PeriodicalIF":0.0,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12373301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D total body photography, a promising innovation for early skin cancer detection: scoping review.","authors":"Fran Baete, Alyssa Laura Jakers, Nele Vande Velde, Griet Voet","doi":"10.2196/68510","DOIUrl":"https://doi.org/10.2196/68510","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Skin cancer is a global health concern due to its high and still increasing incidence and associated healthcare cost. Belgium is no exception as one in five people are diagnosed with skin cancer before the age of 75. A promising innovation, the VECTRA WB360, a three-dimensional total body photography system allows clinicians to objectively compare the totality of the skin on a macroscopic level on further appointments. The integrated lesion visualisation software allows automated detection, counts and assessment of skin lesions. And detailed comparison of individual lesions is possible through the attached digital dermatoscope.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aims to review available literature on the use of the Vectra in research and clinical settings, and to summarise the clinical utility, advantages and limitations reported for this system.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;An electronic literature search was conducted on PubMed from December 2023 - March 2024 using a combination of following search terms: 3D imaging, VECTRA WB360, melanoma, non-melanoma skin cancer, their synonyms and associated entry terms. Publications that used a device other than the Vectra WB360 were excluded, as were articles reporting on new technology without further research or without added cases. After thorough screening of the articles and removal of duplicates, 11 articles remained.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Our literature search yielded 11 relevant papers, which included 2 case studies, 6 prospective and 3 retrospective studies. According to multiple studies, the VECTRA WB360 images were of a high enough quality to allow on-screen diagnosis of some melanoma and nonmelanoma skin cancers by dermatologists. Sensitivity compared to face to face examination for melanoma is unknown. The integrated lesion visualisation software is capable of detecting and counting naevi and distinguishing melanoma from other skin lesions with high accuracy, with convolutional neural network (CNN) integration further enhancing its sensitivity and specificity. However, it is important to note that no comparison to the usual standard of care was made. Also, dermatologists achieved greater specificity and thus remained superior to machine and artificial intelligence.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;While the VECTRA 3D TBP holds substantial promise for the early detection and monitoring of skin cancer, its application cannot yet replace the expertise of trained clinicians. Although the lesion visualizer and DEXI score offer potential enhancements, they also pose risks, including a significant increase in unnecessary excisions due to lower specificity. Despite these promising results, expert overview is still recommended and superior, since there is not enough evidence yet that 3D TBP and/or AI is reliable on its own or beneficial as a support tool Given the small samples and lack of blinded trials, further studies are needed to explore an","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ChatGPT-4's Level of Dermatological Knowledge Based on Board Examination Review Questions and Bloom's Taxonomy.","authors":"Hansen Tai, Carrie Kovarik","doi":"10.2196/74085","DOIUrl":"10.2196/74085","url":null,"abstract":"<p><strong>Unlabelled: </strong>Our study demonstrated the ability of ChatGPT-4 to answer 77.5% of all sampled text-based board review type questions correctly. Questions requiring the recall of factual information were answered correctly most often, with slight decreases in correctness as higher-order thinking requirements increased. Improvements to ChatGPT's visual diagnostics capabilities will be required before it can be used reliably for clinical decision-making and visual diagnostics.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e74085"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shared Delusional Parasitosis in Two Families: Clinical Insights Into Folie à Deux and Folie à Trois.","authors":"Gökçe Işıl Kurmuş, Hanife Karataş, Elif Erdem, Süheyla Doğan Bulut, Müzeyyen Gönül, Selda Pelin Kartal","doi":"10.2196/78398","DOIUrl":"10.2196/78398","url":null,"abstract":"<p><strong>Unlabelled: </strong>Delusional parasitosis is a rare psychotic disorder characterized by individuals firmly believing that they are infested with parasites despite no medical evidence. It may be shared among close contacts-termed folie à deux when 2 individuals are affected or folie à trois when 3 individuals share the delusion. Delusional parasitosis' somatic focus often leads patients to seek dermatologists, causing delayed diagnoses and unnecessary antiparasitic treatments. Herein, we present 2 familial cases of shared delusional parasitosis. In both cases, patients exhibited the matchbox sign, presenting nonparasitic materials as \"evidence\" of infestation. Dermatological and psychiatric evaluations excluded organic causes, diagnosing primary delusional parasitosis. Treatment with antipsychotic medications led to symptom remission. Psychoeducation was critical in preventing relapse in secondary cases. Delusional parasitosis with shared delusions is often misdiagnosed, requiring dermatologists to recognize it early. A multidisciplinary approach that combines psychiatric care and psychoeducation is essential for effective management and for preventing the reinforcement of delusional beliefs.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"8 ","pages":"e78398"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}