JMIR dermatology最新文献

{"title":"Topical Application of Tea Tree Oil for the Treatment of Verruca Vulgaris.","authors":"Deenadayalan Boopalan, Venugopal Vijayakumar, Poornima Ravi, Maheshkumar Kuppusamy","doi":"10.2196/47107","DOIUrl":"10.2196/47107","url":null,"abstract":"Deenadayalan Boopalan, MD; Venugopal Vijayakumar, PhD; Poornima Ravi, BNYS; Maheshkumar Kuppusamy, PhD 1Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, India 2Department of Yoga, Government Yoga and Naturopathy Medical College and Hospital, Chennai, India 3Department of Clinical Research, Sri Ramachandra Institute of Higher Education and Research, Chennai, India 4Department of Physiology, Government Yoga and Naturopathy Medical College and Hospital, Chennai, India","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e47107"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41142921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outreach Through Facebook: Do Patients With Atopic Dermatitis Provide Clinically Relevant Information When Recruited for Surveys on Social Media?","authors":"Anne Sofie Frølunde, Susanne Thiesen Gren, Anne Grete Frøstrup, Peter Bo Poulsen, Anne Skov Vastrup, Christian Vestergaard","doi":"10.2196/45226","DOIUrl":"10.2196/45226","url":null,"abstract":"Atopic dermatitis (AD) is a common chronic skin disease with a prevalence of up to 20% in children and up to 10% in adults [1]. There has been an increasing focus on the impact on the quality of life of the patients, family members, and caregivers [2], yet performing surveys to elucidate this is often laborious, time-consuming, and expensive. Social media has been used as a new platform for gaining insights into diseases through surveys, but for AD this has not been adequately tested. We have investigated the results obtained from a web-based survey recruiting respondents from a Facebook group hosted by the Danish Atopic Eczema Patients’ Organization (DAEPO) concerning whether it was representative of the population and if it returned relevant information on their disease.","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e45226"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41164217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychodermatological Disorders in Patients With Primary Psychiatric Conditions: Cross-Sectional Study.","authors":"Atinuke Arinola Ajani,&nbsp;Fatai Olatunde Olanrewaju,&nbsp;Olumayowa Abimbola Oninla,&nbsp;Olanrewaju Ibigbami,&nbsp;Samuel Kolawole Mosaku,&nbsp;Olaniyi Emmanuel Onayemi,&nbsp;Olayinka Olasode","doi":"10.2196/47769","DOIUrl":"10.2196/47769","url":null,"abstract":"<p><strong>Background: </strong>Psychodermatological disorders (PDs) and their associations with mental health problems are one of the most frequent research themes in dermatology outpatient settings. Surprisingly, very few studies have been conducted to evaluate PDs among patients with primary psychiatric conditions. As such, the relationship between preexisting psychiatric conditions and comorbid PDs is underrepresented in the literature.</p><p><strong>Objective: </strong>This study examined the prevalence and distribution of PDs among adults with primary psychiatric conditions and determined their association with underlying psychiatric diagnoses.</p><p><strong>Methods: </strong>We conducted a cross-sectional analysis at a tertiary health care facility in southwestern Nigeria. Comorbid PDs were identified and classified using preexisting classification systems. A bivariate analysis was conducted to determine the association between PDs and underlying psychiatric conditions. The level of statistical significance was set at P<.05.</p><p><strong>Results: </strong>The study included 107 patients with mental health disorders, of whom 64 (59.8%) were female. The mean age of the patients was 40.73 (SD 13.08) years. A total of 75 (75/107, 70%) patients had at least one comorbid PD. The prevalence of PDs was highest in patients with affective disorders (15/20, 75%) and least in those with schizophrenia (45/66, 68%). PDs associated with delusions or hallucinations and somatoform symptoms were 9 and 13 times more frequent in patients with anxiety disorders compared to those with other psychiatric conditions (P=.01; odds ratio [OR] 9.88, 95% CI 1.67-58.34 and P=.003; OR 13.13, 95% CI 2.34-73.65), respectively. In contrast, patients with schizophrenia were significantly less likely to be diagnosed with dermatoses resulting from delusions or hallucinations (P=.002; OR 0.04, 95% CI 0.00-0.75). A weak but significant negative association was also found between psychophysiological PDs and anxiety disorders (ϕ=-0.236; P=.02).</p><p><strong>Conclusions: </strong>This study provides important insights into the overwhelming burden of psychodermatological conditions in patients with mental health disorders and specific associations with underlying psychiatric diagnosis.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e47769"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10580141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41171149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Survey of Patient Demographics in Inflammatory Skin Disease Case Reports.","authors":"Ross O'Hagan,&nbsp;Stella A Caldas,&nbsp;Patrick M Brunner,&nbsp;Benjamin Ungar","doi":"10.2196/49070","DOIUrl":"10.2196/49070","url":null,"abstract":"<p><p>Case reports serve many functions in the medical literature. We explore patient demographics in case reports for common inflammatory skin diseases.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e49070"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41175487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosing the Dermatologic Blues: Systematic Review of the Rare Conundrum, Psychogenic Purpura.","authors":"Praneet K Gill,&nbsp;Amy Zeglinski-Spinney","doi":"10.2196/48153","DOIUrl":"10.2196/48153","url":null,"abstract":"<p><strong>Background: </strong>Psychogenic purpura is an idiopathic psychodermatologic condition of recurrent, painful purpura precipitated by psychological stress, predominantly affecting young females. Little consensus exists on the diagnostic guidelines for this rare condition, often resulting in costly, unnecessary, and stressful investigations as well as prolonged hospital admissions.</p><p><strong>Objective: </strong>With this first up-to-date systematic review of 134 cases of psychogenic purpura in over a decade, we aim to thoroughly investigate the diagnostic strategy and treatment regimens used in the last decade. With a sooner diagnosis, patient stress and nosocomial ecchymoses can be minimized, and treatment can be expedited.</p><p><strong>Methods: </strong>We conducted a literature review of 4 databases (PubMed, Ovid Embase, Ovid MEDLINE, and Web of Science) on October 5, 2022 that yielded 46 full-text articles, which were reviewed and extracted by 2 independent reviewers.</p><p><strong>Results: </strong>We analyzed a total of 134 cases, consisting largely of females (125/134, 93.3%) with purpura on the upper (103/134, 76.9%) or lower limbs (112/134, 83.6%). Apart from a paresthesia prodrome, patients commonly experienced headaches, malaise, and arthralgia or myalgia. Approximately 70% (95/134) of patients reported a physiological or psychological stressor or psychiatric diagnosis before the development of the purpura. Laboratory testing almost always revealed unremarkable results. The intradermal washed autoerythrocyte sensitization test was positive in 98% (42/43) of cases. Histopathology biopsy findings commonly revealed dermal erythrodiapedesis or hemorrhage (n=34) and perivascular inflammatory infiltrates (n=17). Approximately 42% (56/134) of patients received a novel psychiatric diagnosis, with depression being the most common (40/72, 56%). In both patients with and those without a novel psychiatric diagnosis, observation, counseling, treatment with antidepressants (ie, selective serotonin reuptake inhibitors), and psychotherapy (ie, cognitive behavioral therapy) prevailed in the resolution of the purpura.</p><p><strong>Conclusions: </strong>Due to the unclear etiology and infrequent presentation of this condition, it remains a diagnosis of exclusion based on clinical suspicion evaluating the presence of stressors or psychiatric comorbidities and exclusion of systemic conditions. Clinical confirmation can be sought through a positive autoerythrocyte sedimentation test, characteristic histopathology findings, and remission of purpura after psychiatric treatment.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e48153"},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10534291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10228412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Health Risks, Dermatological Manifestations, and Environmental Justice Associated With Vinyl Chloride Exposure: Narrative Review.","authors":"Rachel S Goodman,&nbsp;Lavanya Mittal,&nbsp;Eva Rawlings Parker","doi":"10.2196/48998","DOIUrl":"10.2196/48998","url":null,"abstract":"<p><strong>Background: </strong>Environmental vinyl chloride (VC) exposure may result in serious acute and chronic dermatological conditions. Because existing literature largely focuses on exposures in occupational settings, a gap persists in our understanding of the medical consequences of large-scale chemical spills.</p><p><strong>Objective: </strong>This study aims to examine the potential dermatological manifestations of VC exposure in the context of industrial spills and other environmental disasters and to highlight the public health and justice implications of such releases.</p><p><strong>Methods: </strong>In this narrative review, relevant evidence-based, peer-reviewed scientific sources, gray literature, and media reports were identified via searches of search PubMed and Google using predetermined keyword search terms related to VC, VC spills and releases, train derailment, cutaneous disease, public health, and vulnerable and marginalized populations.</p><p><strong>Results: </strong>Contact dermatitis and frostbite may arise acutely, highlighting the importance of swift decontamination. Long-term manifestations from chronic VC exposure due to persistence in environmental reservoirs include Raynaud disease, sclerodermatous skin changes, acro-osteolysis, and cutaneous malignancies. The clinical severity of cutaneous manifestations is influenced by individual susceptibility as well as duration, intensity, and route of exposure. Additionally, chemical releases of VC more frequently impact Communities of Color and those of lower socioeconomic status, resulting in greater rates of exposure-related disease.</p><p><strong>Conclusions: </strong>With environmental release events of hazardous chemicals becoming increasingly common and because the skin has increased contact with environmental toxins relative to other organs, an urgent need exists for a greater understanding of the overall short- and long-term health impacts of large-scale, toxic exposures, underscoring the need for ongoing clinical vigilance. Dermatologists and public health officials should also aim to better understand the ways in which the disproportionate impacts of hazardous chemical exposures on lower-income and minority populations may exacerbate existing health disparities. Herein, we describe the health implications of toxic releases with particular consideration paid to marginalized and vulnerable populations. In addition to legal and regulatory frameworks, we advocate for improved public health measures, to not only mitigate the risk of environmental catastrophes in the future, but also ensure timely and effective responses to them.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e48998"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10183896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Public Interest in Mpox via Google Trends, YouTube, and TikTok.","authors":"Nicholas Comeau,&nbsp;Alyssa Abdelnour,&nbsp;Kurt Ashack","doi":"10.2196/48827","DOIUrl":"10.2196/48827","url":null,"abstract":"<p><p>Public response to the recent Mpox outbreak was analyzed using internet search trends and social media posts.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e48827"},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10168879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Global Digital Impact of Psoriasis Action Month and World Psoriasis Day: Serial Cross-Sectional Study.","authors":"Kashish Malhotra,&nbsp;Pranshul Aggarwal,&nbsp;Sakshi Malhotra,&nbsp;Kashish Goyal","doi":"10.2196/49399","DOIUrl":"10.2196/49399","url":null,"abstract":"<jats:p />","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e49399"},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10507516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10156268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prescribing Patterns of Dupilumab for Atopic Dermatitis in Adults: Retrospective, Observational Cohort Study.","authors":"Torunn E Sivesind,&nbsp;Ani Oganesyan,&nbsp;Grace Bosma,&nbsp;Camille Hochheimer,&nbsp;Lisa M Schilling,&nbsp;Robert Dellavalle","doi":"10.2196/41194","DOIUrl":"https://doi.org/10.2196/41194","url":null,"abstract":"<p><strong>Background: </strong>Atopic dermatitis (AD) is a common inflammatory disease caused by a type 2 T helper cell-mediated immune response to environmental antigens. Approximately 1 in 5 patients with AD presents with moderate to severe disease, and treatments approved by the Food and Drug Administration include emollients, topical glucocorticoids, and calcineurin inhibitors. Dupilumab, a fully human monoclonal antibody, improves AD via inhibition of interleukin-4 and interleukin-13.</p><p><strong>Objective: </strong>Our aim was to characterize the prescribing patterns of dupilumab for AD in adults at a large university-affiliated health system.</p><p><strong>Methods: </strong>A retrospective, observational cohort study was conducted using electronic data from the Observational Health Data Sciences and Informatics database, assessing data from the University of Colorado Medical Campus and its affiliates. The outcome measured was the prevalence of dupilumab prescribed for adults with AD (n=6421), between March 28, 2013, and March 28, 2021. We assessed whether the characteristics of patients who received dupilumab were different from those who did not. Each patient characteristic was assessed using a univariate logistic regression with the binary outcome of receiving or not receiving dupilumab.</p><p><strong>Results: </strong>We found a population prevalence of 5.6% (6421/114,476) for AD. In our cohort, Black patients with AD were more than twice as likely to have received dupilumab compared to White patients (odds ratio 2.352, 95% CI 1.58-3.39). Patients with a diagnosis of atopic neurodermatitis were approximately twice as likely to have received dupilumab compared to those with other diagnostic variants of AD (odds ratio 1.87, 95% CI 1.01-3.22).</p><p><strong>Conclusions: </strong>Our results demonstrate that both patient racial characteristics and specific AD diagnoses were associated with variations in dupilumab prescription patterns.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e41194"},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10262926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saliency-Enhanced Content-Based Image Retrieval for Diagnosis Support in Dermatology Consultation: Reader Study.","authors":"Mathias Gassner,&nbsp;Javier Barranco Garcia,&nbsp;Stephanie Tanadini-Lang,&nbsp;Fabio Bertoldo,&nbsp;Fabienne Fröhlich,&nbsp;Matthias Guckenberger,&nbsp;Silvia Haueis,&nbsp;Christin Pelzer,&nbsp;Mauricio Reyes,&nbsp;Patrick Schmithausen,&nbsp;Dario Simic,&nbsp;Ramon Staeger,&nbsp;Fabio Verardi,&nbsp;Nicolaus Andratschke,&nbsp;Andreas Adelmann,&nbsp;Ralph P Braun","doi":"10.2196/42129","DOIUrl":"https://doi.org/10.2196/42129","url":null,"abstract":"<p><strong>Background: </strong>Previous research studies have demonstrated that medical content image retrieval can play an important role by assisting dermatologists in skin lesion diagnosis. However, current state-of-the-art approaches have not been adopted in routine consultation, partly due to the lack of interpretability limiting trust by clinical users.</p><p><strong>Objective: </strong>This study developed a new image retrieval architecture for polarized or dermoscopic imaging guided by interpretable saliency maps. This approach provides better feature extraction, leading to better quantitative retrieval performance as well as providing interpretability for an eventual real-world implementation.</p><p><strong>Methods: </strong>Content-based image retrieval (CBIR) algorithms rely on the comparison of image features embedded by convolutional neural network (CNN) against a labeled data set. Saliency maps are computer vision-interpretable methods that highlight the most relevant regions for the prediction made by a neural network. By introducing a fine-tuning stage that includes saliency maps to guide feature extraction, the accuracy of image retrieval is optimized. We refer to this approach as saliency-enhanced CBIR (SE-CBIR). A reader study was designed at the University Hospital Zurich Dermatology Clinic to evaluate SE-CBIR's retrieval accuracy as well as the impact of the participant's confidence on the diagnosis.</p><p><strong>Results: </strong>SE-CBIR improved the retrieval accuracy by 7% (77% vs 84%) when doing single-lesion retrieval against traditional CBIR. The reader study showed an overall increase in classification accuracy of 22% (62% vs 84%) when the participant is provided with SE-CBIR retrieved images. In addition, the overall confidence in the lesion's diagnosis increased by 24%. Finally, the use of SE-CBIR as a support tool helped the participants reduce the number of nonmelanoma lesions previously diagnosed as melanoma (overdiagnosis) by 53%.</p><p><strong>Conclusions: </strong>SE-CBIR presents better retrieval accuracy compared to traditional CBIR CNN-based approaches. Furthermore, we have shown how these support tools can help dermatologists and residents improve diagnosis accuracy and confidence. Additionally, by introducing interpretable methods, we should expect increased acceptance and use of these tools in routine consultation.</p>","PeriodicalId":73553,"journal":{"name":"JMIR dermatology","volume":"6 ","pages":"e42129"},"PeriodicalIF":0.0,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10485719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10245118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}